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疾病ID:TCMBANKDI019452
疾病名:Hyperlipidemia, Familial Combined
MeSH_Name:Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases
HPO_Name:Abnormality of metabolism/homeostasis
UMLS_Name:Disease or Syndrome
DO_Name:disease of metabolism; genetic disease
疾病类型:disease
DisGeNET_Link:C0020474
MeSH_Link:C16; C18
HPO_Link:HP:0001939
UMLS_Link:T047
DO_Link:DOID:0014667; DOID:630
HERB_ID:HBDIS001437
疾病对应的植物
| ID | 拉丁名 | 药名 | 药用植物名 | 功能与主治 | 来源 | 药用部位 | 使用民族 |
|---|
疾病对应的化合物
| 化合物ID | 化合物名 | 别名 | 分子式 | 分子质量 | Smiles |
|---|
疾病对应的靶点
| 靶点ID | 基因名 | 基因别名 | 描述 |
|---|
| TCMBANKGE010971 | FABP2 | FABPI; I-FABP | fatty acid binding protein 2 |
| TCMBANKGE000288 | ATF6 | ACHM7; ATF6A | activating transcription factor 6 |
| TCMBANKGE000781 | LDLR | FH; FHC; FHCL1; LDLCQ2 | low density lipoprotein receptor |
| TCMBANKGE004505 | OSBPL9 | ORP-9; ORP9 | oxysterol binding protein like 9 |
| TCMBANKGE014003 | IGFBP2 | IBP2; IGF-BP53 | insulin like growth factor binding protein 2 |
| TCMBANKGE000429 | CD36 | BDPLT10; CHDS7; FAT; GP3B; GP4; GPIV; PASIV; SCARB3 | CD36 molecule |
| TCMBANKGE000260 | APOB | FCHL2; FLDB; LDLCQ4; apoB-100; apoB-48 | apolipoprotein B |
| TCMBANKGE012703 | LIPC | HDLCQ12; HL; HTGL; LIPH | lipase C, hepatic type |
| TCMBANKGE010104 | LYPLA2 | APT-2; APT2; DJ886K2.4 | lysophospholipase 2 |
| TCMBANKGE011588 | HNF4A | FRTS4; HNF4; HNF4a7; HNF4a8; HNF4a9; HNF4alpha; MODY; MODY1; NR2A1; NR2A21; TCF; TCF14 | hepatocyte nuclear factor 4 alpha |
| TCMBANKGE000539 | FAT1 | CDHF7; CDHR8; FAT; ME5; hFat1 | FAT atypical cadherin 1 |
| TCMBANKGE013080 | MLXIPL | CHREBP; MIO; MLX; MONDOB; WBSCR14; WS-bHLH; bHLHd14 | MLX interacting protein like |
| TCMBANKGE007174 | FADS3 | CYB5RP; LLCDL3 | fatty acid desaturase 3 |
| TCMBANKGE000832 | ABCG8 | GBD4; STSL; STSL1 | ATP binding cassette subfamily G member 8 |
| TCMBANKGE000833 | ABCG5 | STSL; STSL2 | ATP binding cassette subfamily G member 5 |
| TCMBANKGE006134 | ADD1 | ADDA | adducin 1 |
| TCMBANKGE012649 | APOA2 | Apo-AII; ApoA-II; apoAII | apolipoprotein A2 |
| TCMBANKGE000653 | TCF7L2 | TCF-4; TCF4 | transcription factor 7 like 2 |
| TCMBANKGE004039 | SIGLEC7 | AIRM1; CD328; CDw328; D-siglec; QA79; SIGLEC-7; SIGLEC19P; SIGLECP2; p75; p75/AIRM1 | sialic acid binding Ig like lectin 7 |
| TCMBANKGE008857 | LPL | HDLCQ11; LIPD | lipoprotein lipase |
| TCMBANKGE000230 | ADIPOQ | ACDC; ACRP30; ADIPQTL1; ADPN; APM-1; APM1; GBP28 | adiponectin, C1Q and collagen domain containing |
| TCMBANKGE014338 | IL2RB | CD122; IL15RB; IMD63; P70-75 | interleukin 2 receptor subunit beta |
| TCMBANKGE000258 | EGR1 | AT225; G0S30; KROX-24; NGFI-A; TIS8; ZIF-268; ZNF225 | early growth response 1 |
| TCMBANKGE000882 | SERPINE1 | PAI; PAI-1; PAI1; PLANH1 | serpin family E member 1 |
| TCMBANKGE000692 | PNPLA2 | 1110001C14Rik; ATGL; FP17548; PEDF-R; TTS-2.2; TTS2; iPLA2zeta | patatin like phospholipase domain containing 2 |
| TCMBANKGE006461 | CUX1 | CASP; CDP; CDP/Cut; CDP1; COY1; CUTL1; CUX; Clox; Cux/CDP; GDDI; GOLIM6; Nbla10317; p100; p110; p200; p75 | cut like homeobox 1 |
| TCMBANKGE007077 | PSIP1 | DFS70; LEDGF; PAIP; PSIP2; p52; p75 | PC4 and SFRS1 interacting protein 1 |
| TCMBANKGE013290 | OSBPL10 | ORP10; OSBP9 | oxysterol binding protein like 10 |
| TCMBANKGE009570 | LPA | AK38; APOA; LP | lipoprotein(a) |
| TCMBANKGE000271 | APOE | AD2; APO-E; ApoE4; LDLCQ5; LPG | apolipoprotein E |
| TCMBANKGE005082 | APOA1 | HPALP2; apo(a) | apolipoprotein A1 |
| TCMBANKGE014837 | LEPR | CD295; LEP-R; LEPRD; OB-R; OBR | leptin receptor |
| TCMBANKGE001138 | LIPE | AOMS4; FPLD6; HSL; LHS | lipase E, hormone sensitive type |
| TCMBANKGE000792 | FASLG | ALPS1B; APT1LG1; APTL; CD178; CD95-L; CD95L; FASL; TNFSF6; TNLG1A | Fas ligand |
| TCMBANKGE014110 | C3 | AHUS5; ARMD9; ASP; C3a; C3b; CPAMD1; HEL-S-62p | complement C3 |
| TCMBANKGE009368 | USF1 | FCHL; FCHL1; HYPLIP1; MLTF; MLTFI; UEF; bHLHb11 | upstream transcription factor 1 |
| TCMBANKGE013504 | RXRG | NR2B3; RXRC | retinoid X receptor gamma |
| TCMBANKGE000224 | AGT | ANHU; SERPINA8; hFLT1 | angiotensinogen |
| TCMBANKGE004266 | AR | AIS; AR8; DHTR; HUMARA; HYSP1; KD; NR3C4; SBMA; SMAX1; TFM | androgen receptor |
| TCMBANKGE000163 | TNFRSF1B | CD120b; TBPII; TNF-R-II; TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80; p75; p75TNFR | TNF receptor superfamily member 1B |
| TCMBANKGE001158 | LEP | LEPD; OB; OBS | leptin |
| TCMBANKGE001141 | PPARA | NR1C1; PPAR; PPARalpha; hPPAR | peroxisome proliferator activated receptor alpha |
| TCMBANKGE006400 | PLG | - | plasminogen |
| TCMBANKGE010775 | PCDH15 | CDHR15; DFNB23; USH1F | protocadherin related 15 |
| TCMBANKGE009274 | TGIF1 | HPE4; TGIF | TGFB induced factor homeobox 1 |
| TCMBANKGE011621 | APOA5 | APOAV; RAP3 | apolipoprotein A5 |
| TCMBANKGE005422 | CD59 | 16.3A5; 1F5; EJ16; EJ30; EL32; G344; HRF-20; HRF20; MAC-IP; MACIF; MEM43; MIC11; MIN1; MIN2; MIN3; MIRL; MSK21; p18-20 | CD59 molecule (CD59 blood group) |
| TCMBANKGE011547 | APOC3 | APOCIII | apolipoprotein C3 |
| TCMBANKGE006553 | PON1 | ESA; MVCD5; PON | paraoxonase 1 |
| TCMBANKGE009874 | CDKN2B | CDK4I; INK4B; MTS2; P15; TP15; p15INK4b | cyclin dependent kinase inhibitor 2B |
| TCMBANKGE000299 | HMGCR | LDLCQ3 | 3-hydroxy-3-methylglutaryl-CoA reductase |
| TCMBANKGE005662 | ALB | HSA; PRO0883; PRO0903; PRO1341 | albumin |
| TCMBANKGE009361 | GPT | AAT1; ALT1; GPT1 | glutamic--pyruvic transaminase |
| TCMBANKGE003272 | TCF3 | AGM8; E2A; E47; ITF1; TCF-3; VDIR; bHLHb21; p75 | transcription factor 3 |
| TCMBANKGE000214 | SCD | FADS5; MSTP008; SCD1; SCDOS; hSCD1 | stearoyl-CoA desaturase |
| TCMBANKGE012634 | CRABP2 | CRABP-II; RBP6 | cellular retinoic acid binding protein 2 |
| TCMBANKGE001185 | PPARG | CIMT1; GLM1; NR1C3; PPARG1; PPARG2; PPARG5; PPARgamma | peroxisome proliferator activated receptor gamma |
| TCMBANKGE015070 | HCLS1 | CTTNL; HS1; lckBP1; p75 | hematopoietic cell-specific Lyn substrate 1 |
| TCMBANKGE000884 | FN1 | CIG; ED-B; FINC; FN; FNZ; GFND; GFND2; LETS; MSF; SMDCF | fibronectin 1 |
| TCMBANKGE012726 | MTTP | ABL; MTP | microsomal triglyceride transfer protein |
| TCMBANKGE001134 | IRS1 | HIRS-1 | insulin receptor substrate 1 |
| TCMBANKGE014176 | ANGPT2 | AGPT2; ANG2 | angiopoietin 2 |
| TCMBANKGE006417 | DLX4 | BP1; DLX7; DLX8; DLX9; OFC15 | distal-less homeobox 4 |
| TCMBANKGE001070 | UCP1 | SLC25A7; UCP | uncoupling protein 1 |
| TCMBANKGE001054 | ABCA1 | ABC-1; ABC1; CERP; HDLCQTL13; HDLDT1; HPALP1; TGD | ATP binding cassette subfamily A member 1 |
| TCMBANKGE001116 | CYP7A1 | CP7A; CYP7; CYPVII | cytochrome P450 family 7 subfamily A member 1 |
| TCMBANKGE010787 | CHIT1 | CHI3; CHIT; CHITD | chitinase 1 |
| TCMBANKGE005793 | VLDLR | CAMRQ1; CARMQ1; CHRMQ1; VLDL-R; VLDLRCH | very low density lipoprotein receptor |
| TCMBANKGE000584 | TXNIP | ARRDC6; EST01027; HHCPA78; THIF; VDUP1 | thioredoxin interacting protein |
| TCMBANKGE000326 | SELP | CD62; CD62P; GMP140; GRMP; LECAM3; PADGEM; PSEL | selectin P |
| TCMBANKGE000644 | TNFRSF1A | CD120a; FPF; TBP1; TNF-R; TNF-R-I; TNF-R55; TNFAR; TNFR1; TNFR55; TNFR60; p55; p55-R; p60 | TNF receptor superfamily member 1A |
| TCMBANKGE000783 | PCSK9 | FH3; FHCL3; HCHOLA3; LDLCQ1; NARC-1; NARC1; PC9 | proprotein convertase subtilisin/kexin type 9 |
| TCMBANKGE004455 | APOA4 | - | apolipoprotein A4 |
| TCMBANKGE009580 | SERPINB2 | HsT1201; PAI; PAI-2; PAI2; PLANH2 | serpin family B member 2 |
| TCMBANKGE000203 | KHSRP | FBP2; FUBP2; KSRP; p75 | KH-type splicing regulatory protein |
| TCMBANKGE000140 | EIF4EBP1 | 4E-BP1; 4EBP1; BP-1; PHAS-I | eukaryotic translation initiation factor 4E binding protein 1 |
| TCMBANKGE007202 | CETP | BPIFF; HDLCQ10 | cholesteryl ester transfer protein |
| TCMBANKGE004930 | LCAT | - | lecithin-cholesterol acyltransferase |
滇IICP备16009434号-1 |
Dai SX Lab