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疾病ID:TCMBANKDI021278
疾病名:Severe myopia
MeSH_Name:Eye Diseases
HPO_Name:Abnormality of the eye
UMLS_Name:Disease or Syndrome
DO_Name:-
疾病类型:disease
DisGeNET_Link:C0271183
MeSH_Link:C11
HPO_Link:HP:0000478
UMLS_Link:T047
DO_Link:-
HERB_ID:-
疾病对应的植物
| ID | 拉丁名 | 药名 | 药用植物名 | 功能与主治 | 来源 | 药用部位 | 使用民族 |
|---|
疾病对应的化合物
| 化合物ID | 化合物名 | 别名 | 分子式 | 分子质量 | Smiles |
|---|
疾病对应的靶点
| 靶点ID | 基因名 | 基因别名 | 描述 |
|---|
| TCMBANKGE002851 | MFRP | CTRP5; MCOP5; NNO2; RD6 | membrane frizzled-related protein |
| TCMBANKGE002250 | GJD2 | CX36; GJA9 | gap junction protein delta 2 |
| TCMBANKGE006401 | ATP6V1A | ARCL2D; ATP6A1; ATP6V1A1; HO68; IECEE3; VA68; VPP2; Vma1 | ATPase H+ transporting V1 subunit A |
| TCMBANKGE013729 | OPN1LW | CBBM; CBP; COD5; RCP; ROP | opsin 1, long wave sensitive |
| TCMBANKGE007677 | UHRF1BP1L | SHIP164 | UHRF1 binding protein 1 like |
| TCMBANKGE011281 | P4HA2 | MYP25 | prolyl 4-hydroxylase subunit alpha 2 |
| TCMBANKGE013782 | LTBP2 | C14orf141; GLC3D; LTBP3; MSPKA; MSTP031; WMS3 | latent transforming growth factor beta binding protein 2 |
| TCMBANKGE014158 | VIP | PHM27 | vasoactive intestinal peptide |
| TCMBANKGE012837 | ATP6V1E1 | ARCL2C; ATP6E; ATP6E2; ATP6V1E; P31; Vma4 | ATPase H+ transporting V1 subunit E1 |
| TCMBANKGE001104 | TGFB2 | G-TSF; LDS4; TGF-beta2 | transforming growth factor beta 2 |
| TCMBANKGE001197 | FOS | AP-1; C-FOS; p55 | Fos proto-oncogene, AP-1 transcription factor subunit |
| TCMBANKGE008065 | COL11A1 | CO11A1; COLL6; DFNA37; STL2 | collagen type XI alpha 1 chain |
| TCMBANKGE003359 | TBC1D24 | DFNA65; DFNB86; DOORS; EIEE16; EPRPDC; FIME; TLDC6 | TBC1 domain family member 24 |
| TCMBANKGE014680 | PLK3 | CNK; FNK; PLK-3; PRK | polo like kinase 3 |
| TCMBANKGE000313 | JUN | AP-1; AP1; c-Jun; cJUN; p39 | Jun proto-oncogene, AP-1 transcription factor subunit |
| TCMBANKGE014420 | GNB3 | CSNB1H | G protein subunit beta 3 |
| TCMBANKGE009966 | ACAN | AGC1; AGCAN; CSPG1; CSPGCP; MSK16; SEDK; SSOAOD | aggrecan |
| TCMBANKGE011890 | CABP4 | CRSD; CSNB2B | calcium binding protein 4 |
| TCMBANKGE008550 | RRH | - | retinal pigment epithelium-derived rhodopsin homolog |
| TCMBANKGE002561 | COL9A2 | DJ39G22.4; EDM2; MED; STL5 | collagen type IX alpha 2 chain |
| TCMBANKGE008187 | SNTB1 | 59-DAP; A1B; BSYN2; DAPA1B; SNT2; SNT2B1; TIP-43 | syntrophin beta 1 |
| TCMBANKGE000871 | IGFBP3 | BP-53; IBP3 | insulin like growth factor binding protein 3 |
| TCMBANKGE004460 | RASGRF1 | CDC25; CDC25L; GNRP; GRF1; GRF55; H-GRF55; PP13187; ras-GRF1 | Ras protein specific guanine nucleotide releasing factor 1 |
| TCMBANKGE010745 | PRELP | MST161; MSTP161; SLRR2A | proline and arginine rich end leucine rich repeat protein |
| TCMBANKGE009871 | GRM6 | CSNB1B; GPRC1F; MGLUR6; mGlu6 | glutamate metabotropic receptor 6 |
| TCMBANKGE001915 | INS-IGF2 | INSIGF | INS-IGF2 readthrough |
| TCMBANKGE000435 | PROM1 | AC133; CD133; CORD12; MCDR2; MSTP061; PROML1; RP41; STGD4 | prominin 1 |
| TCMBANKGE005031 | RIN2 | MACS; RASSF4 | Ras and Rab interactor 2 |
| TCMBANKGE014699 | COL9A1 | DJ149L1.1.2; EDM6; MED; STL4 | collagen type IX alpha 1 chain |
| TCMBANKGE013160 | LAMA1 | LAMA; PTBHS; S-LAM-alpha | laminin subunit alpha 1 |
| TCMBANKGE003495 | ZNRF3 | BK747E2.3; RNF203 | zinc and ring finger 3 |
| TCMBANKGE005933 | LUM | LDC; SLRR2D | lumican |
| TCMBANKGE000568 | MET | AUTS9; DFNB97; HGFR; RCCP2; c-Met | MET proto-oncogene, receptor tyrosine kinase |
| TCMBANKGE000015 | ADORA2A | A2aR; ADORA2; RDC8 | adenosine A2a receptor |
| TCMBANKGE000258 | EGR1 | AT225; G0S30; KROX-24; NGFI-A; TIS8; ZIF-268; ZNF225 | early growth response 1 |
| TCMBANKGE000872 | IGF1R | CD221; IGFIR; IGFR; JTK13 | insulin like growth factor 1 receptor |
| TCMBANKGE012557 | SLC39A5 | LZT-Hs7; MYP24; ZIP5 | solute carrier family 39 member 5 |
| TCMBANKGE012642 | COL18A1 | GLCC; KNO; KNO1; KS | collagen type XVIII alpha 1 chain |
| TCMBANKGE000201 | ESR1 | ER; ESR; ESRA; ESTRR; Era; NR3A1 | estrogen receptor 1 |
| TCMBANKGE001038 | SERPINF1 | EPC-1; OI12; OI6; PEDF; PIG35 | serpin family F member 1 |
| TCMBANKGE004092 | GGCT | C7orf24; CRF21; GCTG; GGC | gamma-glutamylcyclotransferase |
| TCMBANKGE012756 | SLC19A1 | CHMD; FOLT; IFC-1; IFC1; REFC; RFC; RFC1; RFT-1; hRFC; hSLC19A1 | solute carrier family 19 member 1 |
| TCMBANKGE006337 | GRK1 | GPRK1; RHOK; RK | G protein-coupled receptor kinase 1 |
| TCMBANKGE014353 | ERBB3 | ErbB-3; FERLK; HER3; LCCS2; MDA-BF-1; c-erbB-3; c-erbB3; erbB3-S; p180-ErbB3; p45-sErbB3; p85-sErbB3 | erb-b2 receptor tyrosine kinase 3 |
| TCMBANKGE012664 | OPTC | OPT | opticin |
| TCMBANKGE004955 | CCDC102B | ACY1L; AN; C18orf14; HsT1731 | coiled-coil domain containing 102B |
| TCMBANKGE012594 | RHO | CSNBAD1; OPN2; RP4 | rhodopsin |
| TCMBANKGE000462 | ARR3 | ARRX; MYP26; cArr | arrestin 3 |
| TCMBANKGE005267 | SETD1A | EPEDD; KMT2F; Set1; Set1A | SET domain containing 1A, histone lysine methyltransferase |
| TCMBANKGE001037 | MMP2 | CLG4; CLG4A; MMP-2; MMP-II; MONA; TBE-1 | matrix metallopeptidase 2 |
| TCMBANKGE010044 | CREBZF | SMILE; ZF | CREB/ATF bZIP transcription factor |
| TCMBANKGE008796 | HSD17B6 | HSE; RODH; SDR9C6 | hydroxysteroid 17-beta dehydrogenase 6 |
| TCMBANKGE006708 | RPGR | COD1; CORDX1; CRD; PCDX; RP15; RP3; XLRP3; orf15 | retinitis pigmentosa GTPase regulator |
| TCMBANKGE000160 | COL2A1 | ANFH; AOM; COL11A3; SEDC; STL1 | collagen type II alpha 1 chain |
| TCMBANKGE005922 | LPIN2 | - | lipin 2 |
| TCMBANKGE011001 | KERA | CNA2; KTN; SLRR2B | keratocan |
| TCMBANKGE013042 | MIPEP | COXPD31; HMIP; MIP | mitochondrial intermediate peptidase |
| TCMBANKGE012219 | CACNA2D4 | RCD4 | calcium voltage-gated channel auxiliary subunit alpha2delta 4 |
| TCMBANKGE012655 | CLDN19 | HOMG5 | claudin 19 |
| TCMBANKGE000479 | TIMP1 | CLGI; EPA; EPO; HCI; TIMP; TIMP-1 | TIMP metallopeptidase inhibitor 1 |
| TCMBANKGE013496 | BMP2K | BIKE; HRIHFB2017 | BMP2 inducible kinase |
| TCMBANKGE007866 | SAG | RP47; S-AG | S-antigen visual arrestin |
| TCMBANKGE008429 | CACNA1F | AIED; COD3; COD4; CORDX; CORDX3; CSNB2; CSNB2A; CSNBX2; Cav1.4; Cav1.4alpha1; JM8; JMC8; OA2 | calcium voltage-gated channel subunit alpha1 F |
| TCMBANKGE003228 | LRP2 | DBS; GP330; LRP-2 | LDL receptor related protein 2 |
| TCMBANKGE001482 | TNKS | ARTD5; PARP-5a; PARP5A; PARPL; TIN1; TINF1; TNKS1; pART5 | tankyrase |
| TCMBANKGE004724 | FBN1 | ACMICD; ECTOL1; FBN; GPHYSD2; MASS; MFLS; MFS1; OCTD; SGS; SSKS; WMS; WMS2 | fibrillin 1 |
| TCMBANKGE002043 | CTNND2 | GT24; NPRAP | catenin delta 2 |
| TCMBANKGE001687 | PDE6B | CSNB3; CSNBAD2; GMP-PDEbeta; PDEB; RP40; rd1 | phosphodiesterase 6B |
| TCMBANKGE007504 | HSD3B1 | 3BETAHSD; HSD3B; HSDB3; HSDB3A; SDR11E1 | hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 |
| TCMBANKGE005666 | DCN | CSCD; DSPG2; PG40; PGII; PGS2; SLRR1B | decorin |
| TCMBANKGE001697 | MMP1 | CLG; CLGN | matrix metallopeptidase 1 |
| TCMBANKGE000200 | CYP1B1 | ASGD6; CP1B; CYPIB1; GLC3A; P4501B1 | cytochrome P450 family 1 subfamily B member 1 |
| TCMBANKGE005782 | NDP | EVR2; FEVR; ND | norrin cystine knot growth factor NDP |
| TCMBANKGE014926 | RSPO1 | CRISTIN3; RSPO | R-spondin 1 |
| TCMBANKGE009274 | TGIF1 | HPE4; TGIF | TGFB induced factor homeobox 1 |
| TCMBANKGE005132 | GRM8 | GLUR8; GPRC1H; MGLUR8; mGlu8 | glutamate metabotropic receptor 8 |
| TCMBANKGE001477 | RDH8 | PRRDH; SDR28C2 | retinol dehydrogenase 8 |
| TCMBANKGE010690 | PLXNA2 | OCT; PLXN2 | plexin A2 |
| TCMBANKGE005013 | CRYBA4 | CTRCT23; CYRBA4; MCOPCT4 | crystallin beta A4 |
| TCMBANKGE002680 | SCO2 | CEMCOX1; ECGF1; Gliostatin; MYP6; PD-ECGF; SCO1L; TP; TYMP; TdRPase | synthesis of cytochrome C oxidase 2 |
| TCMBANKGE007470 | SLC24A1 | CSNB1D; HsT17412; NCKX; NCKX1; RODX | solute carrier family 24 member 1 |
| TCMBANKGE007894 | CRIPT | HSPC139; SSMDF | CXXC repeat containing interactor of PDZ3 domain |
| TCMBANKGE012548 | FMOD | FM; SLRR2E | fibromodulin |
| TCMBANKGE010312 | EPYC | DSPG3; PGLB; Pg-Lb; SLRR3B | epiphycan |
| TCMBANKGE000643 | TTR | ATTR; CTS; CTS1; HEL111; HsT2651; PALB; TBPA | transthyretin |
| TCMBANKGE007130 | BCOR | ANOP2; MAA2; MCOPS2 | BCL6 corepressor |
| TCMBANKGE004120 | IRX5 | HMMS; IRX-2a; IRXB2 | iroquois homeobox 5 |
| TCMBANKGE012213 | TRPM1 | CSNB1C; LTRPC1; MLSN1 | transient receptor potential cation channel subfamily M member 1 |
| TCMBANKGE009062 | GZF1 | JLSM; ZBTB23; ZNF336 | GDNF inducible zinc finger protein 1 |
| TCMBANKGE000251 | FGF2 | BFGF; FGF-2; FGFB; HBGF-2 | fibroblast growth factor 2 |
| TCMBANKGE000988 | HGF | DFNB39; F-TCF; HGFB; HPTA; SF | hepatocyte growth factor |
| TCMBANKGE000198 | KCNMA1 | BKTM; CADEDS; IEG16; KCa1.1; LIWAS; MaxiK; PNKD3; SAKCA; SLO; SLO-ALPHA; SLO1; bA205K10.1; hSlo; mSLO1 | potassium calcium-activated channel subfamily M alpha 1 |
| TCMBANKGE001125 | IGF1 | IGF; IGF-I; IGFI; MGF | insulin like growth factor 1 |
| TCMBANKGE000419 | SMS | MRSR; SPMSY; SRS; SpS | spermine synthase |
| TCMBANKGE001134 | IRS1 | HIRS-1 | insulin receptor substrate 1 |
| TCMBANKGE007543 | INSR | CD220; HHF5 | insulin receptor |
| TCMBANKGE002679 | LAMA2 | LAMM; MDC1A | laminin subunit alpha 2 |
| TCMBANKGE013106 | TIMP3 | HSMRK222; K222; K222TA2; SFD | TIMP metallopeptidase inhibitor 3 |
| TCMBANKGE005728 | BBS12 | C4orf24 | Bardet-Biedl syndrome 12 |
| TCMBANKGE013790 | BPTF | FAC1; FALZ; NEDDFL; NURF301 | bromodomain PHD finger transcription factor |
| TCMBANKGE000186 | IGF2 | C11orf43; GRDF; IGF-II; PP9974 | insulin like growth factor 2 |
| TCMBANKGE009459 | TMTC3 | LIS8; SMILE | transmembrane O-mannosyltransferase targeting cadherins 3 |
| TCMBANKGE001108 | BMP2 | BDA2; BMP2A; SSFSC | bone morphogenetic protein 2 |
| TCMBANKGE004977 | VIPR2 | C16DUPq36.3; DUP7q36.3; PACAP-R-3; PACAP-R3; VIP-R-2; VPAC2; VPAC2R; VPCAP2R | vasoactive intestinal peptide receptor 2 |
| TCMBANKGE007328 | PAX6 | AN; AN1; AN2; ASGD5; D11S812E; FVH1; MGDA; WAGR | paired box 6 |
| TCMBANKGE005300 | PLOD1 | EDS6; EDSKCL1; LH; LH1; LLH; PLOD | procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 |
| TCMBANKGE007036 | KCNQ5 | Kv7.5; MRD46 | potassium voltage-gated channel subfamily Q member 5 |
| TCMBANKGE002997 | RPE | RPE2-1 | ribulose-5-phosphate-3-epimerase |
| TCMBANKGE004792 | BICC1 | BICC; CYSRD | BicC family RNA binding protein 1 |
| TCMBANKGE003929 | ADH7 | ADH4 | alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide |
| TCMBANKGE004607 | RAB28 | CORD18 | RAB28, member RAS oncogene family |
| TCMBANKGE000172 | IGFBP1 | AFBP; IBP1; IGF-BP25; PP12; hIGFBP-1 | insulin like growth factor binding protein 1 |
| TCMBANKGE012031 | RAB8A | MEL; RAB8 | RAB8A, member RAS oncogene family |
| TCMBANKGE012224 | VDR | NR1I1; PPP1R163 | vitamin D receptor |
| TCMBANKGE008399 | RPL41 | L41 | ribosomal protein L41 |
| TCMBANKGE010186 | RARB | HAP; MCOPS12; NR1B2; RARbeta1; RRB2 | retinoic acid receptor beta |
| TCMBANKGE000389 | MMP3 | CHDS6; MMP-3; SL-1; STMY; STMY1; STR1 | matrix metallopeptidase 3 |
| TCMBANKGE006320 | IGFBP4 | BP-4; HT29-IGFBP; IBP4; IGFBP-4 | insulin like growth factor binding protein 4 |
| TCMBANKGE005266 | ZNF469 | BCS; BCS1; Zfp469 | zinc finger protein 469 |
| TCMBANKGE010558 | NYX | CLRP; CSNB1; CSNB1A; CSNB4; NBM1 | nyctalopin |
| TCMBANKGE000414 | CYP19A1 | ARO; ARO1; CPV1; CYAR; CYP19; CYPXIX; P-450AROM | cytochrome P450 family 19 subfamily A member 1 |
| TCMBANKGE013837 | CNGB3 | ACHM1 | cyclic nucleotide gated channel subunit beta 3 |
| TCMBANKGE000147 | OPA1 | BERHS; MGM1; MTDPS14; NPG; NTG; largeG | OPA1 mitochondrial dynamin like GTPase |
| TCMBANKGE005708 | AMIGO2 | ALI1; AMIGO-2; DEGA | adhesion molecule with Ig like domain 2 |
| TCMBANKGE012302 | PRDM5 | BCS2; PFM2 | PR/SET domain 5 |
| TCMBANKGE014626 | FGF10 | - | fibroblast growth factor 10 |
| TCMBANKGE006197 | AMD1 | ADOMETDC; AMD; SAMDC | adenosylmethionine decarboxylase 1 |
| TCMBANKGE005535 | CHRM1 | HM1; M1; M1R | cholinergic receptor muscarinic 1 |
| TCMBANKGE000541 | CRYAB | CMD1II; CRYA2; CTPP2; CTRCT16; HEL-S-101; HSPB5; MFM2 | crystallin alpha B |
| TCMBANKGE007827 | ZNF644 | BM-005; MYP21; NatF; ZEP-2 | zinc finger protein 644 |
| TCMBANKGE007151 | TIMP2 | CSC-21K; DDC8 | TIMP metallopeptidase inhibitor 2 |
| TCMBANKGE000712 | COL1A1 | CAFYD; EDSARTH1; EDSC; OI1; OI2; OI3; OI4 | collagen type I alpha 1 chain |
| TCMBANKGE001986 | PTPRR | EC-PTP; PCPTP1; PTP-SL; PTPBR7; PTPRQ | protein tyrosine phosphatase receptor type R |
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Dai SX Lab