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疾病ID:TCMBANKDI022433
疾病名:Idiopathic pulmonary hypertension
MeSH_Name:Respiratory Tract Diseases; Cardiovascular Diseases
HPO_Name:-
UMLS_Name:Disease or Syndrome
DO_Name:disease of anatomical entity
疾病类型:disease
DisGeNET_Link:C0152171
MeSH_Link:C08; C14
HPO_Link:-
UMLS_Link:T047
DO_Link:DOID:7
HERB_ID:HBDIS003685
疾病对应的植物
| ID | 拉丁名 | 药名 | 药用植物名 | 功能与主治 | 来源 | 药用部位 | 使用民族 |
|---|
疾病对应的化合物
| 化合物ID | 化合物名 | 别名 | 分子式 | 分子质量 | Smiles |
|---|
疾病对应的靶点
| 靶点ID | 基因名 | 基因别名 | 描述 |
|---|
| TCMBANKGE011020 | FHL1 | FCMSU; FHL-1; FHL1A; FHL1B; FLH1A; KYOT; RBMX1A; RBMX1B; SLIM; SLIM-1; SLIM1; SLIMMER; XMPMA | four and a half LIM domains 1 |
| TCMBANKGE003913 | HBG2 | HBG-T1; TNCY | hemoglobin subunit gamma 2 |
| TCMBANKGE000473 | TRPC6 | FSGS2; TRP6 | transient receptor potential cation channel subfamily C member 6 |
| TCMBANKGE000070 | CAV1 | BSCL3; CGL3; LCCNS; MSTP085; PPH3; VIP21 | caveolin 1 |
| TCMBANKGE003804 | FGFR2 | BBDS; BEK; BFR-1; CD332; CEK3; CFD1; ECT1; JWS; K-SAM; KGFR; TK14; TK25 | fibroblast growth factor receptor 2 |
| TCMBANKGE000915 | BMPR2 | BMPR-II; BMPR3; BMR2; BRK-3; POVD1; PPH1; T-ALK | bone morphogenetic protein receptor type 2 |
| TCMBANKGE014158 | VIP | PHM27 | vasoactive intestinal peptide |
| TCMBANKGE000144 | POU5F1P3 | OCT3; OCT4; OCT4-pg3; OTF-3; OTF3; OTF3L; Oct-3; Oct-4; POU5F1; POU5F1L; POU5FLC12 | POU class 5 homeobox 1 pseudogene 3 |
| TCMBANKGE011654 | NPS | - | neuropeptide S |
| TCMBANKGE008011 | HTR2A | 5-HT2A; HTR2 | 5-hydroxytryptamine receptor 2A |
| TCMBANKGE003095 | F2RL1 | GPR11; PAR2 | F2R like trypsin receptor 1 |
| TCMBANKGE009264 | RPSA | 37LRP; 67LR; ICAS; LAMBR; LAMR1; LBP; LBP/p40; LRP; LRP/LR; NEM/1CHD4; SA; lamR; p40 | ribosomal protein SA |
| TCMBANKGE000752 | Il33 | 9230117N10Rik; Il-33; Il1f11; NF-HEV | interleukin 33 |
| TCMBANKGE004616 | RBM45 | DRB1; RB-1 | RNA binding motif protein 45 |
| TCMBANKGE011981 | PDE3B | HcGIP1; cGIPDE1 | phosphodiesterase 3B |
| TCMBANKGE003680 | ADORA2B | ADORA2 | adenosine A2b receptor |
| TCMBANKGE000229 | ACE2 | ACEH | angiotensin I converting enzyme 2 |
| TCMBANKGE003590 | SMAD9 | MADH6; MADH9; PPH2; SMAD8; SMAD8/9; SMAD8A; SMAD8B | SMAD family member 9 |
| TCMBANKGE004272 | DVL2 | - | dishevelled segment polarity protein 2 |
| TCMBANKGE003904 | VTN | V75; VN; VNT | vitronectin |
| TCMBANKGE001146 | SNAI1 | SLUGH2; SNA; SNAH; SNAIL; SNAIL1; dJ710H13.1 | snail family transcriptional repressor 1 |
| TCMBANKGE000274 | CCL2 | GDCF-2; HC11; HSMCR30; MCAF; MCP-1; MCP1; SCYA2; SMC-CF | C-C motif chemokine ligand 2 |
| TCMBANKGE000723 | FOSL2 | FRA2 | FOS like 2, AP-1 transcription factor subunit |
| TCMBANKGE009021 | HLA-DQB1 | CELIAC1; HLA-DQB; IDDM1 | major histocompatibility complex, class II, DQ beta 1 |
| TCMBANKGE000230 | ADIPOQ | ACDC; ACRP30; ADIPQTL1; ADPN; APM-1; APM1; GBP28 | adiponectin, C1Q and collagen domain containing |
| TCMBANKGE009024 | SLC52A1 | GPCR42; GPR172B; PAR2; RBFVD; RFT1; RFVT1; hRFT1; huPAR-2 | solute carrier family 52 member 1 |
| TCMBANKGE000304 | KCNA5 | ATFB7; HCK1; HK2; HPCN1; KV1.5; PCN1 | potassium voltage-gated channel subfamily A member 5 |
| TCMBANKGE006649 | ANO1 | DOG1; ORAOV2; TAOS2; TMEM16A | anoctamin 1 |
| TCMBANKGE000015 | ADORA2A | A2aR; ADORA2; RDC8 | adenosine A2a receptor |
| TCMBANKGE000298 | SOD1 | ALS; ALS1; HEL-S-44; IPOA; SOD; STAHP; hSod1; homodimer | superoxide dismutase 1 |
| TCMBANKGE000872 | IGF1R | CD221; IGFIR; IGFR; JTK13 | insulin like growth factor 1 receptor |
| TCMBANKGE000882 | SERPINE1 | PAI; PAI-1; PAI1; PLANH1 | serpin family E member 1 |
| TCMBANKGE000960 | STAT5A | MGF; STAT5 | signal transducer and activator of transcription 5A |
| TCMBANKGE001844 | TGFBR3 | BGCAN; betaglycan | transforming growth factor beta receptor 3 |
| TCMBANKGE010320 | BMPR1B | ALK-6; ALK6; AMDD; BDA1D; BDA2; CDw293 | bone morphogenetic protein receptor type 1B |
| TCMBANKGE011827 | KCNK3 | K2p3.1; OAT1; PPH4; TASK; TASK-1; TASK1; TBAK1 | potassium two pore domain channel subfamily K member 3 |
| TCMBANKGE001142 | CHDH | - | choline dehydrogenase |
| TCMBANKGE000321 | NOX4 | KOX; KOX-1; RENOX | NADPH oxidase 4 |
| TCMBANKGE006922 | YWHAB | GW128; HEL-S-1; HS1; KCIP-1; YWHAA | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta |
| TCMBANKGE013523 | ENG | END; HHT1; ORW1 | endoglin |
| TCMBANKGE011364 | GDF15 | GDF-15; MIC-1; MIC1; NAG-1; PDF; PLAB; PTGFB | growth differentiation factor 15 |
| TCMBANKGE013170 | ELANE | ELA2; GE; HLE; HNE; NE; PMN-E; SCN1 | elastase, neutrophil expressed |
| TCMBANKGE000536 | EDNRB | ABCDS; ET-B; ET-BR; ETB; ETB1; ETBR; ETRB; HSCR; HSCR2; WS4A | endothelin receptor type B |
| TCMBANKGE006224 | PTGIR | IP; PRIPR | prostaglandin I2 receptor |
| TCMBANKGE001107 | NOS3 | ECNOS; eNOS | nitric oxide synthase 3 |
| TCMBANKGE006255 | SP1 | - | Sp1 transcription factor |
| TCMBANKGE006309 | KCNMB1 | BKbeta1; K(VCA)beta; SLO-BETA; hbeta1; hslo-beta; k(VCA)beta-1; slo-beta-1 | potassium calcium-activated channel subfamily M regulatory beta subunit 1 |
| TCMBANKGE013582 | SOD3 | EC-SOD | superoxide dismutase 3 |
| TCMBANKGE000769 | EIF2AK4 | GCN2; PVOD2 | eukaryotic translation initiation factor 2 alpha kinase 4 |
| TCMBANKGE010442 | SETD2 | HBP231; HIF-1; HIP-1; HSPC069; HYPB; KMT3A; LLS; SET2; p231HBP | SET domain containing 2, histone lysine methyltransferase |
| TCMBANKGE014640 | TIMP4 | TIMP-4 | TIMP metallopeptidase inhibitor 4 |
| TCMBANKGE004597 | ATL3 | HSN1F | atlastin GTPase 3 |
| TCMBANKGE000199 | ICAM1 | BB2; CD54; P3.58 | intercellular adhesion molecule 1 |
| TCMBANKGE000479 | TIMP1 | CLGI; EPA; EPO; HCI; TIMP; TIMP-1 | TIMP metallopeptidase inhibitor 1 |
| TCMBANKGE013868 | DYM | DMC; SMC | dymeclin |
| TCMBANKGE014529 | ENO1 | ENO1L1; HEL-S-17; MPB1; NNE; PPH | enolase 1 |
| TCMBANKGE001097 | HIF1A | HIF-1-alpha; HIF-1A; HIF-1alpha; HIF1; HIF1-ALPHA; MOP1; PASD8; bHLHe78 | hypoxia inducible factor 1 subunit alpha |
| TCMBANKGE005014 | FGL2 | T49; pT49 | fibrinogen like 2 |
| TCMBANKGE014582 | CLIC4 | CLIC4L; H1; MTCLIC; huH1; p64H1 | chloride intracellular channel 4 |
| TCMBANKGE004047 | PDE5A | CGB-PDE; CN5A; PDE5 | phosphodiesterase 5A |
| TCMBANKGE000318 | HMGB1 | HMG-1; HMG1; HMG3; SBP-1 | high mobility group box 1 |
| TCMBANKGE014851 | TRPC3 | SCA41; TRP3 | transient receptor potential cation channel subfamily C member 3 |
| TCMBANKGE000999 | FOXM1 | FKHL16; FOXM1A; FOXM1B; FOXM1C; HFH-11; HFH11; HNF-3; INS-1; MPHOSPH2; MPP-2; MPP2; PIG29; TRIDENT | forkhead box M1 |
| TCMBANKGE000224 | AGT | ANHU; SERPINA8; hFLT1 | angiotensinogen |
| TCMBANKGE004266 | AR | AIS; AR8; DHTR; HUMARA; HYSP1; KD; NR3C4; SBMA; SMAX1; TFM | androgen receptor |
| TCMBANKGE001113 | ACTA2 | ACTSA | actin alpha 2, smooth muscle |
| TCMBANKGE000765 | TRPM7 | ALSPDC; CHAK; CHAK1; LTRPC7; LTrpC-7; TRP-PLIK | transient receptor potential cation channel subfamily M member 7 |
| TCMBANKGE001154 | CREB1 | CREB; CREB-1 | cAMP responsive element binding protein 1 |
| TCMBANKGE001007 | NR1I2 | BXR; ONR1; PAR; PAR1; PAR2; PARq; PRR; PXR; SAR; SXR | nuclear receptor subfamily 1 group I member 2 |
| TCMBANKGE001088 | SMAD4 | DPC4; JIP; MADH4; MYHRS | SMAD family member 4 |
| TCMBANKGE000273 | LOX | AAT10 | lysyl oxidase |
| TCMBANKGE006400 | PLG | - | plasminogen |
| TCMBANKGE000222 | EDN1 | ARCND3; ET1; HDLCQ7; PPET1; QME | endothelin 1 |
| TCMBANKGE000257 | FLT1 | FLT; FLT-1; VEGFR-1; VEGFR1 | fms related receptor tyrosine kinase 1 |
| TCMBANKGE005666 | DCN | CSCD; DSPG2; PG40; PGII; PGS2; SLRR1B | decorin |
| TCMBANKGE000652 | STAT5B | STAT5 | signal transducer and activator of transcription 5B |
| TCMBANKGE009342 | F10 | FX; FXA | coagulation factor X |
| TCMBANKGE004421 | KNG1 | BDK; BK; HMWK; KNG | kininogen 1 |
| TCMBANKGE000428 | SERPINA1 | A1A; A1AT; AAT; PI; PI1; PRO2275; alpha1AT; nNIF | serpin family A member 1 |
| TCMBANKGE012736 | CA9 | CAIX; MN | carbonic anhydrase 9 |
| TCMBANKGE000956 | NR1H4 | BAR; FXR; HRR-1; HRR1; PFIC5; RIP14 | nuclear receptor subfamily 1 group H member 4 |
| TCMBANKGE011074 | RNPEP | AP-B; APB | arginyl aminopeptidase |
| TCMBANKGE011407 | PDGFA | PDGF-A; PDGF1 | platelet derived growth factor subunit A |
| TCMBANKGE006344 | ADAMTS13 | ADAM-TS13; ADAMTS-13; C9orf8; VWFCP; vWF-CP | ADAM metallopeptidase with thrombospondin type 1 motif 13 |
| TCMBANKGE000109 | ACTB | BRWS1; PS1TP5BP1 | actin beta |
| TCMBANKGE000860 | LGALS3 | CBP35; GAL3; GALBP; GALIG; L31; LGALS2; MAC2 | galectin 3 |
| TCMBANKGE000622 | SLPI | ALK1; ALP; BLPI; HUSI; HUSI-I; MPI; WAP4; WFDC4 | secretory leukocyte peptidase inhibitor |
| TCMBANKGE000795 | POU5F1 | OCT3; OCT4; OTF-3; OTF3; OTF4; Oct-3; Oct-4 | POU class 5 homeobox 1 |
| TCMBANKGE008240 | MSH2 | COCA1; FCC1; HNPCC; HNPCC1; LCFS2; hMSH2 | mutS homolog 2 |
| TCMBANKGE001149 | PPARGC1A | LEM6; PGC-1(alpha); PGC-1alpha; PGC-1v; PGC1; PGC1A; PPARGC1 | PPARG coactivator 1 alpha |
| TCMBANKGE003053 | HTR2B | 5-HT(2B); 5-HT-2B; 5-HT2B | 5-hydroxytryptamine receptor 2B |
| TCMBANKGE010969 | LRP1 | A2MR; APOER; APR; CD91; IGFBP-3R; IGFBP3R; IGFBP3R1; KPA; LRP; LRP1A; TGFBR5 | LDL receptor related protein 1 |
| TCMBANKGE011235 | SLC8A1 | NCX1 | solute carrier family 8 member A1 |
| TCMBANKGE002559 | CFH | AHUS1; AMBP1; ARMD4; ARMS1; CFHL3; FH; FHL1; HF; HF1; HF2; HUS | complement factor H |
| TCMBANKGE003082 | HDAC3 | HD3; KDAC3; RPD3; RPD3-2 | histone deacetylase 3 |
| TCMBANKGE009742 | HLA-DRB1 | DRB1; HLA-DR1B; HLA-DRB; SS1 | major histocompatibility complex, class II, DR beta 1 |
| TCMBANKGE000251 | FGF2 | BFGF; FGF-2; FGFB; HBGF-2 | fibroblast growth factor 2 |
| TCMBANKGE006724 | REN | HNFJ2 | renin |
| TCMBANKGE007252 | IL22 | IL-21; IL-22; IL-D110; IL-TIF; ILTIF; TIFIL-23; TIFa; zcyto18 | interleukin 22 |
| TCMBANKGE001185 | PPARG | CIMT1; GLM1; NR1C3; PPARG1; PPARG2; PPARG5; PPARgamma | peroxisome proliferator activated receptor gamma |
| TCMBANKGE000884 | FN1 | CIG; ED-B; FINC; FN; FNZ; GFND; GFND2; LETS; MSF; SMDCF | fibronectin 1 |
| TCMBANKGE000885 | SPP1 | BNSP; BSPI; ETA-1; OPN | secreted phosphoprotein 1 |
| TCMBANKGE012402 | NTRK1 | MTC; TRK; TRK1; TRKA; Trk-A; p140-TrkA | neurotrophic receptor tyrosine kinase 1 |
| TCMBANKGE000977 | SMAD1 | BSP-1; BSP1; JV4-1; JV41; MADH1; MADR1 | SMAD family member 1 |
| TCMBANKGE001201 | MAPK3 | ERK-1; ERK1; ERT2; HS44KDAP; HUMKER1A; P44ERK1; P44MAPK; PRKM3; p44-ERK1; p44-MAPK | mitogen-activated protein kinase 3 |
| TCMBANKGE000749 | ALOX5 | 5-LO; 5-LOX; 5LPG; LOG5 | arachidonate 5-lipoxygenase |
| TCMBANKGE005223 | TOPBP1 | Dpb11; TOP2BP1 | DNA topoisomerase II binding protein 1 |
| TCMBANKGE002029 | EPAS1 | ECYT4; HIF2A; HLF; MOP2; PASD2; bHLHe73 | endothelial PAS domain protein 1 |
| TCMBANKGE012330 | LIMK1 | LIMK; LIMK-1 | LIM domain kinase 1 |
| TCMBANKGE001108 | BMP2 | BDA2; BMP2A; SSFSC | bone morphogenetic protein 2 |
| TCMBANKGE007547 | BRD2 | BRD2-IT1; D6S113E; FSH; FSRG1; NAT; O27.1.1; RING3; RNF3 | bromodomain containing 2 |
| TCMBANKGE000387 | CTBP1 | BARS; HADDTS | C-terminal binding protein 1 |
| TCMBANKGE000735 | VDAC1 | PORIN; VDAC-1 | voltage dependent anion channel 1 |
| TCMBANKGE008183 | ACE | ACE1; CD143; DCP; DCP1 | angiotensin I converting enzyme |
| TCMBANKGE003597 | SFXN1 | SLC56A1; TCC | sideroflexin 1 |
| TCMBANKGE013473 | F2R | CF2R; HTR; PAR-1; PAR1; TR | coagulation factor II thrombin receptor |
| TCMBANKGE005257 | TK1 | TK2 | thymidine kinase 1 |
| TCMBANKGE003625 | SLC6A4 | 5-HTT; 5-HTTLPR; 5HTT; HTT; OCD1; SERT; SERT1; hSERT | solute carrier family 6 member 4 |
| TCMBANKGE004203 | TGFBR2 | AAT3; FAA3; LDS1B; LDS2; LDS2B; MFS2; RIIC; TAAD2; TBR-ii; TBRII; TGFR-2; TGFbeta-RII | transforming growth factor beta receptor 2 |
| TCMBANKGE001183 | TRPV4 | BCYM3; CMT2C; HMSN2C; OTRPC4; SMAL; SPSMA; SSQTL1; TRP12; VRL2; VROAC | transient receptor potential cation channel subfamily V member 4 |
| TCMBANKGE000236 | BDNF | ANON2; BULN2 | brain derived neurotrophic factor |
| TCMBANKGE001508 | TNFSF4 | CD134L; CD252; GP34; OX-40L; OX4OL; TNLG2B; TXGP1 | TNF superfamily member 4 |
| TCMBANKGE006733 | PVR | CD155; HVED; NECL5; Necl-5; PVS; TAGE4 | PVR cell adhesion molecule |
| TCMBANKGE003539 | PAH | PH; PKU; PKU1 | phenylalanine hydroxylase |
| TCMBANKGE005519 | ENTPD1 | ATPDase; CD39; NTPDase-1; SPG64 | ectonucleoside triphosphate diphosphohydrolase 1 |
| TCMBANKGE006823 | HOXA5 | HOX1; HOX1.3; HOX1C | homeobox A5 |
| TCMBANKGE000771 | TWIST1 | ACS3; BPES2; BPES3; CRS; CRS1; CSO; SCS; SWCOS; TWIST; bHLHa38 | twist family bHLH transcription factor 1 |
| TCMBANKGE013185 | DYNLT1 | CW-1; TCTEL1; tctex-1 | dynein light chain Tctex-type 1 |
| TCMBANKGE000281 | SNAI2 | SLUG; SLUGH; SLUGH1; SNAIL2; WS2D | snail family transcriptional repressor 2 |
| TCMBANKGE006750 | IL21 | CVID11; IL-21; Za11 | interleukin 21 |
| TCMBANKGE002174 | TRPC1 | HTRP-1; TRP1 | transient receptor potential cation channel subfamily C member 1 |
| TCMBANKGE000143 | POU5F1P4 | OCT3; OCT4; OTF-3; OTF3; Oct-3; Oct-4; Oct4-pg4; POU5F1; POU5FLC1 | POU class 5 homeobox 1 pseudogene 4 |
| TCMBANKGE000764 | TRPV1 | VR1 | transient receptor potential cation channel subfamily V member 1 |
| TCMBANKGE000902 | HAS2 | - | hyaluronan synthase 2 |
| TCMBANKGE010841 | ACVRL1 | ACVRLK1; ALK-1; ALK1; HHT; HHT2; ORW2; SKR3; TSR-I | activin A receptor like type 1 |
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Dai SX Lab