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疾病ID:TCMBANKDI023904
疾病名:Macular degeneration
MeSH_Name:Pathological Conditions, Signs and Symptoms; Eye Diseases; Nervous System Diseases
HPO_Name:Abnormality of the eye
UMLS_Name:Disease or Syndrome
DO_Name:disease of anatomical entity
疾病类型:disease
DisGeNET_Link:C0024437
MeSH_Link:C23; C11; C10
HPO_Link:HP:0000478
UMLS_Link:T047
DO_Link:DOID:7
HERB_ID:-
疾病对应的植物
| ID | 拉丁名 | 药名 | 药用植物名 | 功能与主治 | 来源 | 药用部位 | 使用民族 |
|---|
疾病对应的化合物
| 化合物ID | 化合物名 | 别名 | 分子式 | 分子质量 | Smiles |
|---|
| TCMBANKIN036789 | salvianolic acid a | 4CN-1253; AC-20308; 3-(3,4-dihydroxyphenyl)-2-[(E)-3-[2-[(E)-2-(3,4-dihydroxyphenyl)vinyl]-3,4-dihydroxy-phenyl]prop-2-enoyl]oxy-propanoic acid; SCHEMBL10041475; (2R)-3-(3,4-dihydroxyphenyl)-2-[(E)-3-[2-[(E)-2-(3,4-dihydroxyphenyl)ethenyl]-3,4-dihydroxyphenyl]prop-2-enoyl]oxypropanoic acid; 2-(3,4-Dihydroxystyryl)-3,4-dihydroxycinnamic acid alpha-carboxy-3,4-dihydroxyphenethyl ester; Benzenepropanoic acid, a-[[(2E)-3-[2-[(E)-2-(3,4-dihydroxyphenyl)ethenyl]-3,4-dihydroxyphenyl]-1-oxo-2-propenyl]oxy]-3,4-dihydroxy-; Dimethyl methyldopa HCL; Salvianolicacid A; (2R)-3-(3,4-dihydroxyphenyl)-2-[(E)-3-[2-[(E)-2-(3,4-dihydroxyphenyl)vinyl]-3,4-dihydroxy-phenyl]prop-2-enoyl]oxy-propanoic acid; AKOS015965219; 3-(3,4-dihydroxyphenyl)-2-[(E)-3-[2-[(E)-2-(3,4-dihydroxyphenyl)ethenyl]-3,4-dihydroxyphenyl]prop-2-enoyl]oxypropanoic acid; (2R)-3-(3,4-dihydroxyphenyl)-2-[(E)-3-[2-[(E)-2-(3,4-dihydroxyphenyl)vinyl]-3,4-dihydroxy-phenyl]acryloyl]oxy-propionic acid; AC1O1L81; Benzenepropanoic acid, alpha-((3-(2-(2-(3,4-dihydroxyphenyl)ethenyl)-3,4-dihydroxyphenyl)-1-oxo-2-propenyl)oxy)-3,4-dihydroxy-, (R-(E,E))-; BC216311; Salvianolic acid A; 96574-01-5; (2R)-3-(3,4-dihydroxyphenyl)-2-[(E)-3-[2-[(E)-2-(3,4-dihydroxyphenyl)vinyl]-3,4-dihydroxyphenyl]-1-oxoprop-2-enoxy]propanoic acid; (2R)-3-(3,4-dihydroxyphenyl)-2-[(E)-3-[2-[(E)-2-(3,4-dihydroxyphenyl)ethenyl]-3,4-dihydroxy-phenyl]prop-2-enoyl]oxy-propanoic acid; salvianolicacid a; C10492 | C26H22O10 | 494.45 | C1=CC(=C(C=C1CC(C(=O)O)OC(=O)C=CC2=C(C(=C(C=C2)O)O)C=CC3=CC(=C(C=C3)O)O)O)O |
疾病对应的靶点
| 靶点ID | 基因名 | 基因别名 | 描述 |
|---|
| TCMBANKGE002851 | MFRP | CTRP5; MCOP5; NNO2; RD6 | membrane frizzled-related protein |
| TCMBANKGE000429 | CD36 | BDPLT10; CHDS7; FAT; GP3B; GP4; GPIV; PASIV; SCARB3 | CD36 molecule |
| TCMBANKGE001753 | GPX3 | GPx-P; GSHPx-3; GSHPx-P | glutathione peroxidase 3 |
| TCMBANKGE007247 | BBS10 | C12orf58 | Bardet-Biedl syndrome 10 |
| TCMBANKGE013987 | CNGA3 | ACHM2; CCNC1; CCNCa; CCNCalpha; CNCG3; CNG3 | cyclic nucleotide gated channel subunit alpha 3 |
| TCMBANKGE013299 | F3 | CD142; TF; TFA | coagulation factor III, tissue factor |
| TCMBANKGE005715 | AFG3L2 | SCA28; SPAX5 | AFG3 like matrix AAA peptidase subunit 2 |
| TCMBANKGE013293 | ELOVL4 | ADMD; CT118; ISQMR; SCA34; STGD2; STGD3 | ELOVL fatty acid elongase 4 |
| TCMBANKGE000435 | PROM1 | AC133; CD133; CORD12; MCDR2; MSTP061; PROML1; RP41; STGD4 | prominin 1 |
| TCMBANKGE010572 | TST | RDS | thiosulfate sulfurtransferase |
| TCMBANKGE003252 | HTRA1 | ARMD7; CADASIL2; CARASIL; HtrA; L56; ORF480; PRSS11 | HtrA serine peptidase 1 |
| TCMBANKGE000565 | CX3CR1 | CCRL1; CMKBRL1; CMKDR1; GPR13; GPRV28; V28 | C-X3-C motif chemokine receptor 1 |
| TCMBANKGE012642 | COL18A1 | GLCC; KNO; KNO1; KS | collagen type XVIII alpha 1 chain |
| TCMBANKGE001038 | SERPINF1 | EPC-1; OI12; OI6; PEDF; PIG35 | serpin family F member 1 |
| TCMBANKGE011996 | LRRTM4 | - | leucine rich repeat transmembrane neuronal 4 |
| TCMBANKGE001034 | TLR2 | CD282; TIL4 | toll like receptor 2 |
| TCMBANKGE001037 | MMP2 | CLG4; CLG4A; MMP-2; MMP-II; MONA; TBE-1 | matrix metallopeptidase 2 |
| TCMBANKGE006708 | RPGR | COD1; CORDX1; CRD; PCDX; RP15; RP3; XLRP3; orf15 | retinitis pigmentosa GTPase regulator |
| TCMBANKGE014061 | PRPF31 | NY-BR-99; PRP31; RP11; SNRNP61 | pre-mRNA processing factor 31 |
| TCMBANKGE008070 | TTPA | ATTP; AVED; TTP1; alphaTTP | alpha tocopherol transfer protein |
| TCMBANKGE004562 | CP | CP-2 | ceruloplasmin |
| TCMBANKGE006147 | EFEMP1 | DHRD; DRAD; FBLN3; FBNL; FIBL-3; MLVT; MTLV; S1-5 | EGF containing fibulin extracellular matrix protein 1 |
| TCMBANKGE008696 | IMPDH1 | IMPD; IMPD1; IMPDH-I; LCA11; RP10; sWSS2608 | inosine monophosphate dehydrogenase 1 |
| TCMBANKGE003323 | TUBB6 | FPVEPD; HsT1601; TUBB-5 | tubulin beta 6 class V |
| TCMBANKGE010690 | PLXNA2 | OCT; PLXN2 | plexin A2 |
| TCMBANKGE000407 | DYRK1A | DYRK; DYRK1; HP86; MNB; MNBH; MRD7 | dual specificity tyrosine phosphorylation regulated kinase 1A |
| TCMBANKGE015024 | ABCA4 | ABC10; ABCR; ARMD2; CORD3; FFM; RMP; RP19; STGD; STGD1 | ATP binding cassette subfamily A member 4 |
| TCMBANKGE006946 | C1QTNF5 | CTRP5; MFRP | C1q and TNF related 5 |
| TCMBANKGE002559 | CFH | AHUS1; AMBP1; ARMD4; ARMS1; CFHL3; FH; FHL1; HF; HF1; HF2; HUS | complement factor H |
| TCMBANKGE006236 | E2F2 | E2F-2 | E2F transcription factor 2 |
| TCMBANKGE013106 | TIMP3 | HSMRK222; K222; K222TA2; SFD | TIMP metallopeptidase inhibitor 3 |
| TCMBANKGE002360 | CDHR1 | CORD15; PCDH21; PRCAD; RP65 | cadherin related family member 1 |
| TCMBANKGE002997 | RPE | RPE2-1 | ribulose-5-phosphate-3-epimerase |
| TCMBANKGE013837 | CNGB3 | ACHM1 | cyclic nucleotide gated channel subunit beta 3 |
| TCMBANKGE000541 | CRYAB | CMD1II; CRYA2; CTPP2; CTRCT16; HEL-S-101; HSPB5; MFM2 | crystallin alpha B |
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Dai SX Lab