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疾病ID:TCMBANKDI024402
疾病名:Paroxysmal nocturnal hemoglobinuria
MeSH_Name:Hemic and Lymphatic Diseases
HPO_Name:Abnormality of metabolism/homeostasis; Abnormality of the genitourinary system
UMLS_Name:Disease or Syndrome
DO_Name:disease of anatomical entity
疾病类型:disease
DisGeNET_Link:C0024790
MeSH_Link:C15
HPO_Link:HP:0001939; HP:0000119
UMLS_Link:T047
DO_Link:DOID:7
HERB_ID:HBDIS001857
疾病对应的植物
| ID | 拉丁名 | 药名 | 药用植物名 | 功能与主治 | 来源 | 药用部位 | 使用民族 |
|---|
疾病对应的化合物
| 化合物ID | 化合物名 | 别名 | 分子式 | 分子质量 | Smiles |
|---|
疾病对应的靶点
| 靶点ID | 基因名 | 基因别名 | 描述 |
|---|
| TCMBANKGE013394 | ERGIC2 | CDA14; Erv41; PTX1; cd002 | ERGIC and golgi 2 |
| TCMBANKGE005143 | FCGR3B | CD16; CD16A; CD16b; FCG3; FCGR3; FCGR3A; FCR-10; FCRIII; FCRIIIb | Fc fragment of IgG receptor IIIb |
| TCMBANKGE005333 | PIGF | - | phosphatidylinositol glycan anchor biosynthesis class F |
| TCMBANKGE000785 | G6PD | G6PD1 | glucose-6-phosphate dehydrogenase |
| TCMBANKGE006559 | GYPA | CD235a; GPA; GPErik; GPSAT; HGpMiV; HGpMiXI; HGpSta(C); MN; MNS; PAS-2 | glycophorin A (MNS blood group) |
| TCMBANKGE000429 | CD36 | BDPLT10; CHDS7; FAT; GP3B; GP4; GPIV; PASIV; SCARB3 | CD36 molecule |
| TCMBANKGE014689 | CD38 | ADPRC 1; ADPRC1 | CD38 molecule |
| TCMBANKGE010577 | FCGR1A | CD64; CD64A; FCRI; IGFR1 | Fc fragment of IgG receptor Ia |
| TCMBANKGE000915 | BMPR2 | BMPR-II; BMPR3; BMR2; BRK-3; POVD1; PPH1; T-ALK | bone morphogenetic protein receptor type 2 |
| TCMBANKGE000137 | PLAU | ATF; BDPLT5; QPD; UPA; URK; u-PA | plasminogen activator, urokinase |
| TCMBANKGE009073 | PTPRC | B220; CD45; CD45R; GP180; L-CA; LCA; LY5; T200 | protein tyrosine phosphatase receptor type C |
| TCMBANKGE000369 | IFNA1 | IFL; IFN; IFN-ALPHA; IFN-alphaD; IFNA13; IFNA@; leIF D | interferon alpha 1 |
| TCMBANKGE007721 | C5 | C5D; C5a; C5b; CPAMD4; ECLZB | complement C5 |
| TCMBANKGE006173 | TFPI | EPI; LACI; TFI; TFPI1 | tissue factor pathway inhibitor |
| TCMBANKGE004616 | RBM45 | DRB1; RB-1 | RNA binding motif protein 45 |
| TCMBANKGE012222 | IFNA13 | - | interferon alpha 13 |
| TCMBANKGE014168 | ECI2 | ACBD2; DRS-1; DRS1; HCA88; PECI; dJ1013A10.3 | enoyl-CoA delta isomerase 2 |
| TCMBANKGE012202 | GPI | AMF; GNPI; NLK; PGI; PHI; SA-36; SA36 | glucose-6-phosphate isomerase |
| TCMBANKGE000368 | PLAUR | CD87; U-PAR; UPAR; URKR | plasminogen activator, urokinase receptor |
| TCMBANKGE000135 | CXCR4 | CD184; D2S201E; FB22; HM89; HSY3RR; LAP-3; LAP3; LCR1; LESTR; NPY3R; NPYR; NPYRL; NPYY3R; WHIM; WHIMS | C-X-C motif chemokine receptor 4 |
| TCMBANKGE000274 | CCL2 | GDCF-2; HC11; HSMCR30; MCAF; MCP-1; MCP1; SCYA2; SMC-CF | C-C motif chemokine ligand 2 |
| TCMBANKGE000047 | AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | AKT serine/threonine kinase 1 |
| TCMBANKGE009785 | CLYBL | CLB | citramalyl-CoA lyase |
| TCMBANKGE012111 | NEDD4L | NEDD4-2; NEDD4.2; PVNH7; RSP5; hNEDD4-2 | NEDD4 like E3 ubiquitin protein ligase |
| TCMBANKGE000134 | EPO | DBAL; ECYT5; EP; MVCD2 | erythropoietin |
| TCMBANKGE000258 | EGR1 | AT225; G0S30; KROX-24; NGFI-A; TIS8; ZIF-268; ZNF225 | early growth response 1 |
| TCMBANKGE010712 | MME | CALLA; CD10; CMT2T; NEP; SCA43; SFE | membrane metalloendopeptidase |
| TCMBANKGE006522 | HLA-C | D6S204; HLA-JY3; HLAC; HLC-C; MHC; PSORS1 | major histocompatibility complex, class I, C |
| TCMBANKGE006061 | THBD | AHUS6; BDCA3; CD141; THPH12; THRM; TM | thrombomodulin |
| TCMBANKGE000196 | FAS | ALPS1A; APO-1; APT1; CD95; FAS1; FASTM; TNFRSF6 | Fas cell surface death receptor |
| TCMBANKGE008068 | PRTN3 | ACPA; AGP7; C-ANCA; CANCA; MBN; MBT; NP-4; NP4; P29; PR-3; PR3 | proteinase 3 |
| TCMBANKGE011334 | CSF3 | C17orf33; CSF3OS; GCSF | colony stimulating factor 3 |
| TCMBANKGE002180 | CEACAM8 | CD66b; CD67; CGM6; NCA-95 | CEA cell adhesion molecule 8 |
| TCMBANKGE013197 | FCGR3A | CD16; CD16A; FCG3; FCGR3; FCGRIII; FCR-10; FCRIII; FCRIIIA; IGFR3; IMD20 | Fc fragment of IgG receptor IIIa |
| TCMBANKGE011499 | RPL6 | L6; SHUJUN-2; TAXREB107; TXREB1 | ribosomal protein L6 |
| TCMBANKGE000611 | CSF2 | CSF; GMCSF | colony stimulating factor 2 |
| TCMBANKGE001069 | MPO | - | myeloperoxidase |
| TCMBANKGE000154 | CCR2 | CC-CKR-2; CCR-2; CCR2A; CCR2B; CD192; CKR2; CKR2A; CKR2B; CMKBR2; MCP-1-R | C-C motif chemokine receptor 2 |
| TCMBANKGE009412 | C6 | - | complement C6 |
| TCMBANKGE000858 | RBPJ | AOS3; CBF-1; CBF1; IGKJRB; IGKJRB1; KBF2; RBP-J; RBP-J kappa; RBP-JK; RBPJK; RBPSUH; SUH; csl | recombination signal binding protein for immunoglobulin kappa J region |
| TCMBANKGE000078 | BRD4 | CAP; HUNK1; HUNKI; MCAP | bromodomain containing 4 |
| TCMBANKGE000890 | FUT1 | H; HH; HSC | fucosyltransferase 1 (H blood group) |
| TCMBANKGE001126 | NFE2L2 | HEBP1; IMDDHH; NRF2; Nrf-2 | nuclear factor, erythroid 2 like 2 |
| TCMBANKGE014183 | UBL4A | DX254E; DXS254E; G6PD; GDX; GET5; MDY2; TMA24; UBL4 | ubiquitin like 4A |
| TCMBANKGE006806 | FUT4 | CD15; ELFT; FCT3A; FUC-TIV; FUTIV; LeX; SSEA-1 | fucosyltransferase 4 |
| TCMBANKGE001161 | IL2 | IL-2; TCGF; lymphokine | interleukin 2 |
| TCMBANKGE009268 | CTC1 | AAF-132; AAF132; C17orf68; CRMCC; tmp494178 | CST telomere replication complex component 1 |
| TCMBANKGE005969 | THPO | MGDF; MKCSF; ML; MPLLG; THCYT1; TPO | thrombopoietin |
| TCMBANKGE002933 | CR1 | C3BR; C4BR; CD35; KN | complement C3b/C4b receptor 1 (Knops blood group) |
| TCMBANKGE011434 | THY1 | CD90; CDw90 | Thy-1 cell surface antigen |
| TCMBANKGE003789 | HLA-DQA1 | CELIAC1; DQ-A1; DQA1; HLA-DQA | major histocompatibility complex, class II, DQ alpha 1 |
| TCMBANKGE012841 | HLA-A | HLAA | major histocompatibility complex, class I, A |
| TCMBANKGE000297 | JAK2 | JTK10; THCYT3 | Janus kinase 2 |
| TCMBANKGE007385 | NRAS | ALPS4; CMNS; N-ras; NCMS; NRAS1; NS6 | NRAS proto-oncogene, GTPase |
| TCMBANKGE000346 | RPS6KA3 | CLS; HU-3; ISPK-1; MAPKAPK1B; MRX19; RSK; RSK2; S6K-alpha3; p90-RSK2; pp90RSK2 | ribosomal protein S6 kinase A3 |
| TCMBANKGE015117 | CD1D | CD1A; R3; R3G1 | CD1d molecule |
| TCMBANKGE014110 | C3 | AHUS5; ARMD9; ASP; C3a; C3b; CPAMD1; HEL-S-62p | complement C3 |
| TCMBANKGE000001 | CXCR2 | CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB | C-X-C motif chemokine receptor 2 |
| TCMBANKGE010087 | TFRC | CD71; IMD46; T9; TFR; TFR1; TR; TRFR; p90 | transferrin receptor |
| TCMBANKGE000482 | IDH1 | HEL-216; HEL-S-26; IDCD; IDH; IDP; IDPC; PICD | isocitrate dehydrogenase (NADP(+)) 1 |
| TCMBANKGE012929 | EFS | CAS3; CASS3; EFS1; EFS2; HEFS; SIN | embryonal Fyn-associated substrate |
| TCMBANKGE006400 | PLG | - | plasminogen |
| TCMBANKGE000569 | CD34 | - | CD34 molecule |
| TCMBANKGE014116 | CD55 | CHAPLE; CR; CROM; DAF; TC | CD55 molecule (Cromer blood group) |
| TCMBANKGE001188 | CXCL10 | C7; IFI10; INP10; IP-10; SCYB10; crg-2; gIP-10; mob-1 | C-X-C motif chemokine ligand 10 |
| TCMBANKGE012378 | MUL1 | C1orf166; GIDE; MAPL; MULAN; RNF218 | mitochondrial E3 ubiquitin protein ligase 1 |
| TCMBANKGE000956 | NR1H4 | BAR; FXR; HRR-1; HRR1; PFIC5; RIP14 | nuclear receptor subfamily 1 group H member 4 |
| TCMBANKGE005476 | CD160 | BY55; NK1; NK28 | CD160 molecule |
| TCMBANKGE006937 | BST1 | CD157 | bone marrow stromal cell antigen 1 |
| TCMBANKGE006344 | ADAMTS13 | ADAM-TS13; ADAMTS-13; C9orf8; VWFCP; vWF-CP | ADAM metallopeptidase with thrombospondin type 1 motif 13 |
| TCMBANKGE000403 | ATF2 | CRE-BP1; CREB-2; CREB2; HB16; TREB7 | activating transcription factor 2 |
| TCMBANKGE000424 | WT1 | AWT1; GUD; NPHS4; WAGR; WIT-2; WT33 | WT1 transcription factor |
| TCMBANKGE005422 | CD59 | 16.3A5; 1F5; EJ16; EJ30; EL32; G344; HRF-20; HRF20; MAC-IP; MACIF; MEM43; MIC11; MIN1; MIN2; MIN3; MIRL; MSK21; p18-20 | CD59 molecule (CD59 blood group) |
| TCMBANKGE000109 | ACTB | BRWS1; PS1TP5BP1 | actin beta |
| TCMBANKGE002062 | SERPINB6 | CAP; DFNB91; MSTP057; PI-6; PI6; PTI; SPI3 | serpin family B member 6 |
| TCMBANKGE014404 | HMGA2 | BABL; HMGI-C; HMGIC; LIPO; STQTL9 | high mobility group AT-hook 2 |
| TCMBANKGE005941 | FLNA | ABP-280; ABPX; CSBS; CVD1; FGS2; FLN; FLN-A; FLN1; FMD; MNS; NHBP; OPD; OPD1; OPD2; XLVD; XMVD | filamin A |
| TCMBANKGE001144 | CD14 | - | CD14 molecule |
| TCMBANKGE008667 | FLT3LG | FL; FLG3L; FLT3L | fms related receptor tyrosine kinase 3 ligand |
| TCMBANKGE002559 | CFH | AHUS1; AMBP1; ARMD4; ARMS1; CFHL3; FH; FHL1; HF; HF1; HF2; HUS | complement factor H |
| TCMBANKGE008771 | PIGM | GPI-MT-I | phosphatidylinositol glycan anchor biosynthesis class M |
| TCMBANKGE009742 | HLA-DRB1 | DRB1; HLA-DR1B; HLA-DRB; SS1 | major histocompatibility complex, class II, DR beta 1 |
| TCMBANKGE013662 | KLRK1 | CD314; D12S2489E; KLR; NKG2-D; NKG2D | killer cell lectin like receptor K1 |
| TCMBANKGE009440 | PGAP1 | Bst1; ISPD3024; MRT42; SPG67 | post-GPI attachment to proteins inositol deacylase 1 |
| TCMBANKGE010093 | GYPB | CD235b; GPB; GYP; GYPA; MNS; PAS-3; SS | glycophorin B (MNS blood group) |
| TCMBANKGE014999 | CFD | ADIPSIN; ADN; DF; PFD | complement factor D |
| TCMBANKGE009009 | CAP1 | CAP; CAP1-PEN | cyclase associated actin cytoskeleton regulatory protein 1 |
| TCMBANKGE013571 | CELSR3 | ADGRC3; CDHF11; EGFL1; FMI1; HFMI1; MEGF2; RESDA1 | cadherin EGF LAG seven-pass G-type receptor 3 |
| TCMBANKGE001823 | SORBS1 | CAP; FLAF2; R85FL; SH3D5; SH3P12; SORB1 | sorbin and SH3 domain containing 1 |
| TCMBANKGE001125 | IGF1 | IGF; IGF-I; IGFI; MGF | insulin like growth factor 1 |
| TCMBANKGE004839 | GEM | KIR | GTP binding protein overexpressed in skeletal muscle |
| TCMBANKGE012423 | PRNP | ASCR; AltPrP; CD230; CJD; GSS; KURU; PRIP; PrP; PrP27-30; PrP33-35C; PrPc; p27-30 | prion protein |
| TCMBANKGE008175 | PMS1 | HNPCC3; MLH2; PMSL1; hPMS1 | PMS1 homolog 1, mismatch repair system component |
| TCMBANKGE007709 | SERPINC1 | AT3; AT3D; ATIII; ATIII-R2; ATIII-T1; ATIII-T2; THPH7 | serpin family C member 1 |
| TCMBANKGE003143 | FES | FPS | FES proto-oncogene, tyrosine kinase |
| TCMBANKGE000551 | NOL3 | ARC; FCM; MYOCL1; MYP; NOP; NOP30 | nucleolar protein 3 |
| TCMBANKGE004302 | LNPEP | CAP; IRAP; P-LAP; PLAP | leucyl and cystinyl aminopeptidase |
| TCMBANKGE013184 | HP | BP; HP2ALPHA2; HPA1S | haptoglobin |
| TCMBANKGE006961 | F2 | PT; RPRGL2; THPH1 | coagulation factor II, thrombin |
| TCMBANKGE007836 | SELL | CD62L; LAM1; LECAM1; LEU8; LNHR; LSEL; LYAM1; PLNHR; TQ1 | selectin L |
| TCMBANKGE000008 | CD40 | Bp50; CDW40; TNFRSF5; p50 | CD40 molecule |
| TCMBANKGE011523 | HPRT1 | HGPRT; HPRT | hypoxanthine phosphoribosyltransferase 1 |
| TCMBANKGE011182 | ITGB2 | CD18; LAD; LCAMB; LFA-1; MAC-1; MF17; MFI7 | integrin subunit beta 2 |
| TCMBANKGE001590 | CRLS1 | C20orf155; CLS; CLS1; GCD10; dJ967N21.6 | cardiolipin synthase 1 |
| TCMBANKGE010481 | ATP8B1 | ATPIC; BRIC; FIC1; ICP1; PFIC; PFIC1 | ATPase phospholipid transporting 8B1 |
| TCMBANKGE005060 | CD24 | CD24A | CD24 molecule |
| TCMBANKGE009354 | PIGA | GPI3; MCAHS2; PIG-A; PNH1 | phosphatidylinositol glycan anchor biosynthesis class A |
| TCMBANKGE014518 | ARFGEF2 | BIG2; PVNH2; dJ1164I10.1 | ADP ribosylation factor guanine nucleotide exchange factor 2 |
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