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疾病ID:TCMBANKDI026758
疾病名:Muscular Atrophy
MeSH_Name:Pathological Conditions, Signs and Symptoms; Nervous System Diseases
HPO_Name:-
UMLS_Name:Pathologic Function
DO_Name:disease of anatomical entity
疾病类型:phenotype
DisGeNET_Link:C0026846
MeSH_Link:C23; C10
HPO_Link:-
UMLS_Link:T046
DO_Link:DOID:7
HERB_ID:-
疾病对应的植物
| ID | 拉丁名 | 药名 | 药用植物名 | 功能与主治 | 来源 | 药用部位 | 使用民族 |
|---|
疾病对应的化合物
| 化合物ID | 化合物名 | 别名 | 分子式 | 分子质量 | Smiles |
|---|
| TCMBANKIN036829 | ursolic acid | ursolicacid; U6753_SIGMA; AIDS-039057; AKOS022168209; Urs-12-en-28-oic acid, 3beta-hydroxy- (8CI); 77-52-1; s2370; 3beta-Hydroxyurs-12-en-28-oic acid; SMR000445681; NSC4060; MLS000728569; Ursolic acid; TOS-BB-0966; 3beta-Hydroxy-12-ursen-28-ic acid; (1S,2R,4R,6aS,6bR,8aR,10S,12aR,12bR,14bR)-10-hydroxy-1,2,6a,6b,9,9,12a-heptamethyl-2,3,4,4a,5,6,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-octadecahydro-1H-picene-4-carboxylic acid; ursolic acid ; BSPBio_000018; NSC 167406; H719; 89797_FLUKA; EINECS 201-034-0; Prunol; BPBio1_000020; (1S,2R,4aS,6aR,6aS,6bR,8aR,10S,12aR,14bS)-10-hydroxy-1,2,6a,6b,9,9,12a-heptamethyl-2,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydro-1H-picene-4a-carboxylic acid; AI3-03109; CHEBI:9908; ST056289; Ursolicacid; AC-8029; Urs-12-en-28-oic acid, 3-hydroxy-, (3beta)-; Ursolic acid (Malol); CCRIS 7123; BC216337; Urson; (3beta)-3-Hydroxyurs-12-en-28-oic acid; Prestwick3_000089; Malol; C08988; AKOS015965499; SCHEMBL1699371; MolPort-016-633-342; 209545-05-1; AS-13246; AIDS039057; NSC 4060 | C30H48O3 | 456.7 | CC1CCC2(CCC3(C(=CCC4C3(CCC5C4(CCC(C5(C)C)O)C)C)C2C1C)C)C(=O)[O-] |
疾病对应的靶点
| 靶点ID | 基因名 | 基因别名 | 描述 |
|---|
| TCMBANKGE000760 | WWTR1 | TAZ | WW domain containing transcription regulator 1 |
| TCMBANKGE011020 | FHL1 | FCMSU; FHL-1; FHL1A; FHL1B; FLH1A; KYOT; RBMX1A; RBMX1B; SLIM; SLIM-1; SLIM1; SLIMMER; XMPMA | four and a half LIM domains 1 |
| TCMBANKGE015178 | DAG1 | 156DAG; A3a; AGRNR; DAG; LGMDR16; MDDGA9; MDDGC7; MDDGC9 | dystroglycan 1 |
| TCMBANKGE003153 | DMD | BMD; CMD3B; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272; MRX85 | dystrophin |
| TCMBANKGE000338 | CHUK | IKBKA; IKK-alpha; IKK1; IKKA; NFKBIKA; TCF16 | component of inhibitor of nuclear factor kappa B kinase complex |
| TCMBANKGE000697 | APAF1 | APAF-1; CED4 | apoptotic peptidase activating factor 1 |
| TCMBANKGE000047 | AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | AKT serine/threonine kinase 1 |
| TCMBANKGE001028 | HSP90AB1 | D6S182; HSP84; HSP90B; HSPC2; HSPCB | heat shock protein 90 alpha family class B member 1 |
| TCMBANKGE000174 | MSTN | GDF8; MSLHP | myostatin |
| TCMBANKGE000298 | SOD1 | ALS; ALS1; HEL-S-44; IPOA; SOD; STAHP; hSod1; homodimer | superoxide dismutase 1 |
| TCMBANKGE000882 | SERPINE1 | PAI; PAI-1; PAI1; PLANH1 | serpin family E member 1 |
| TCMBANKGE000168 | NR3C1 | GCCR; GCR; GCRST; GR; GRL | nuclear receptor subfamily 3 group C member 1 |
| TCMBANKGE014939 | MYOT | LGMD1; LGMD1A; MFM3; TTID; TTOD | myotilin |
| TCMBANKGE000629 | FBXO32 | Fbx32; MAFbx | F-box protein 32 |
| TCMBANKGE000364 | SMN1 | BCD541; GEMIN1; SMA; SMA1; SMA2; SMA3; SMA4; SMA@; SMN; SMNT; T-BCD541; TDRD16A | survival of motor neuron 1, telomeric |
| TCMBANKGE000121 | KCNH2 | ERG-1; ERG1; H-ERG; HERG; HERG1; Kv11.1; LQT2; SQT1 | potassium voltage-gated channel subfamily H member 2 |
| TCMBANKGE010457 | MUSK | CMS9; FADS; FADS1 | muscle associated receptor tyrosine kinase |
| TCMBANKGE000246 | FOXO1 | FKH1; FKHR; FOXO1A | forkhead box O1 |
| TCMBANKGE010497 | CITED2 | ASD8; MRG-1; MRG1; P35SRJ; VSD2 | Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2 |
| TCMBANKGE002339 | GHR | GHBP; GHIP | growth hormone receptor |
| TCMBANKGE008070 | TTPA | ATTP; AVED; TTP1; alphaTTP | alpha tocopherol transfer protein |
| TCMBANKGE004266 | AR | AIS; AR8; DHTR; HUMARA; HYSP1; KD; NR3C4; SBMA; SMAX1; TFM | androgen receptor |
| TCMBANKGE011129 | GH1 | GH; GH-N; GHB5; GHN; IGHD1A; IGHD1B; IGHD2; hGH-N | growth hormone 1 |
| TCMBANKGE001106 | MTOR | FRAP; FRAP1; FRAP2; RAFT1; RAPT1; SKS | mechanistic target of rapamycin kinase |
| TCMBANKGE010087 | TFRC | CD71; IMD46; T9; TFR; TFR1; TR; TRFR; p90 | transferrin receptor |
| TCMBANKGE000758 | HSF1 | HSTF1 | heat shock transcription factor 1 |
| TCMBANKGE009274 | TGIF1 | HPE4; TGIF | TGFB induced factor homeobox 1 |
| TCMBANKGE005646 | NEDD4 | NEDD4-1; RPF1 | NEDD4 E3 ubiquitin protein ligase |
| TCMBANKGE000666 | RELB | I-REL; IMD53; IREL; REL-B | RELB proto-oncogene, NF-kB subunit |
| TCMBANKGE003269 | ENDOG | - | endonuclease G |
| TCMBANKGE001654 | SGCA | 50DAG; ADL; DAG2; DMDA2; LGMD2D; LGMDR3; SCARMD1; adhalin | sarcoglycan alpha |
| TCMBANKGE001686 | CTSL | CATL; CTSL1; MEP | cathepsin L |
| TCMBANKGE000630 | TRIM63 | IRF; MURF1; MURF2; RNF28; SMRZ | tripartite motif containing 63 |
| TCMBANKGE001044 | RPS6KB1 | PS6K; S6K; S6K-beta-1; S6K1; STK14A; p70 S6KA; p70(S6K)-alpha; p70-S6K; p70-alpha | ribosomal protein S6 kinase B1 |
| TCMBANKGE000286 | GSK3B | - | glycogen synthase kinase 3 beta |
| TCMBANKGE000807 | NAIP | BIRC1; NLRB1; psiNAIP | NLR family apoptosis inhibitory protein |
| TCMBANKGE001125 | IGF1 | IGF; IGF-I; IGFI; MGF | insulin like growth factor 1 |
| TCMBANKGE007850 | CFL1 | CFL; HEL-S-15; cofilin | cofilin 1 |
| TCMBANKGE008225 | COL1A2 | EDSARTH2; EDSCV; OI4 | collagen type I alpha 2 chain |
| TCMBANKGE004337 | AMPD1 | MAD; MADA; MMDD | adenosine monophosphate deaminase 1 |
| TCMBANKGE007976 | CBLB | Cbl-b; Nbla00127; RNF56 | Cbl proto-oncogene B |
| TCMBANKGE000933 | IKBKB | IKK-beta; IKK2; IKKB; IMD15; IMD15A; IMD15B; NFKBIKB | inhibitor of nuclear factor kappa B kinase subunit beta |
| TCMBANKGE012559 | CRHR2 | CRF-RB; CRF2; CRFR2; HM-CRF | corticotropin releasing hormone receptor 2 |
| TCMBANKGE013476 | MTMR4 | FYVE-DSP2; ZFYVE11 | myotubularin related protein 4 |
| TCMBANKGE000459 | PRKAR1A | ACRDYS1; ADOHR; CAR; CNC; CNC1; PKR1; PPNAD1; PRKAR1; TSE1 | protein kinase cAMP-dependent type I regulatory subunit alpha |
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Dai SX Lab