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疾病ID:TCMBANKDI026823
疾病名:Amyotrophic Lateral Sclerosis, Sporadic
MeSH_Name:Nutritional and Metabolic Diseases; Nervous System Diseases
HPO_Name:-
UMLS_Name:Disease or Syndrome
DO_Name:genetic disease; disease of anatomical entity
疾病类型:disease
DisGeNET_Link:C1862941
MeSH_Link:C18; C10
HPO_Link:-
UMLS_Link:T047
DO_Link:DOID:630; DOID:7
HERB_ID:-
疾病对应的植物
| ID | 拉丁名 | 药名 | 药用植物名 | 功能与主治 | 来源 | 药用部位 | 使用民族 |
|---|
疾病对应的化合物
| 化合物ID | 化合物名 | 别名 | 分子式 | 分子质量 | Smiles |
|---|
疾病对应的靶点
| 靶点ID | 基因名 | 基因别名 | 描述 |
|---|
| TCMBANKGE009495 | MASP1 | 3MC1; CRARF; CRARF1; MAP1; MASP; MASP3; MAp44; PRSS5; RaRF | mannan binding lectin serine peptidase 1 |
| TCMBANKGE002265 | TIAM1 | TIAM-1 | TIAM Rac1 associated GEF 1 |
| TCMBANKGE004288 | KIFAP3 | FLA3; KAP-1; KAP-3; KAP3; SMAP; Smg-GDS; dJ190I16.1 | kinesin associated protein 3 |
| TCMBANKGE000781 | LDLR | FH; FHC; FHCL1; LDLCQ2 | low density lipoprotein receptor |
| TCMBANKGE004944 | DCTN1 | DAP-150; DP-150; P135 | dynactin subunit 1 |
| TCMBANKGE002494 | PENK | PE; PENK-A | proenkephalin |
| TCMBANKGE002641 | SLC30A3 | ZNT3 | solute carrier family 30 member 3 |
| TCMBANKGE008862 | KIF3C | - | kinesin family member 3C |
| TCMBANKGE006517 | SLC1A2 | EAAT2; EIEE41; GLT-1; HBGT | solute carrier family 1 member 2 |
| TCMBANKGE005402 | CST3 | ARMD11; HEL-S-2 | cystatin C |
| TCMBANKGE001197 | FOS | AP-1; C-FOS; p55 | Fos proto-oncogene, AP-1 transcription factor subunit |
| TCMBANKGE000096 | TBK1 | FTDALS4; IIAE8; NAK; T2K | TANK binding kinase 1 |
| TCMBANKGE011420 | INPP4B | - | inositol polyphosphate-4-phosphatase type II B |
| TCMBANKGE002926 | SNCG | BCSG1; SR | synuclein gamma |
| TCMBANKGE012887 | ANK3 | ANKYRIN-G; MRT37 | ankyrin 3 |
| TCMBANKGE010385 | CNTN4 | AXCAM; BIG-2 | contactin 4 |
| TCMBANKGE001076 | SOD2 | GClnc1; IPO-B; IPOB; MNSOD; MVCD6; Mn-SOD | superoxide dismutase 2 |
| TCMBANKGE001053 | ABCG1 | ABC8; WHITE1 | ATP binding cassette subfamily G member 1 |
| TCMBANKGE008622 | WNT7A | Wnt-7a | Wnt family member 7A |
| TCMBANKGE013383 | VCP | CDC48; TERA; p97 | valosin containing protein |
| TCMBANKGE008653 | GDI1 | 1A; GDIL; MRX41; MRX48; OPHN2; RABGD1A; RABGDIA; XAP-4 | GDP dissociation inhibitor 1 |
| TCMBANKGE000311 | JUND | AP-1 | JunD proto-oncogene, AP-1 transcription factor subunit |
| TCMBANKGE007365 | IGFALS | ACLSD; ALS | insulin like growth factor binding protein acid labile subunit |
| TCMBANKGE002546 | PFN1 | ALS18 | profilin 1 |
| TCMBANKGE013143 | C1QB | - | complement C1q B chain |
| TCMBANKGE000526 | ATXN1 | ATX1; D6S504E; SCA1 | ataxin 1 |
| TCMBANKGE003479 | NEFH | CMT2CC; NFH | neurofilament heavy |
| TCMBANKGE001146 | SNAI1 | SLUGH2; SNA; SNAH; SNAIL; SNAIL1; dJ710H13.1 | snail family transcriptional repressor 1 |
| TCMBANKGE000265 | SQSTM1 | A170; DMRV; FTDALS3; NADGP; OSIL; PDB3; ZIP3; p60; p62; p62B | sequestosome 1 |
| TCMBANKGE014385 | CHRNA4 | BFNC; EBN; EBN1; NACHR; NACHRA4; NACRA4 | cholinergic receptor nicotinic alpha 4 subunit |
| TCMBANKGE001165 | XIAP | API3; BIRC4; IAP-3; ILP1; MIHA; XLP2; hIAP-3; hIAP3 | X-linked inhibitor of apoptosis |
| TCMBANKGE011798 | ADGRD1 | GPR133; PGR25 | adhesion G protein-coupled receptor D1 |
| TCMBANKGE000756 | BSG | 5F7; CD147; EMMPRIN; EMPRIN; OK; SLC7A11; TCSF | basigin (Ok blood group) |
| TCMBANKGE003601 | CD7 | GP40; LEU-9; TP41; Tp40 | CD7 molecule |
| TCMBANKGE011747 | MATR3 | ALS21; MPD2; VCPDM | matrin 3 |
| TCMBANKGE008888 | CHI3L1 | ASRT7; CGP-39; GP-39; GP39; HC-gp39; HCGP-3P; YK-40; YKL-40; YKL40; YYL-40; hCGP-39 | chitinase 3 like 1 |
| TCMBANKGE000134 | EPO | DBAL; ECYT5; EP; MVCD2 | erythropoietin |
| TCMBANKGE005417 | COASY | DPCK; NBIA6; NBP; PCH12; PPAT; UKR1; pOV-2 | Coenzyme A synthase |
| TCMBANKGE013655 | SLC33A1 | ACATN; AT-1; AT1; CCHLND; SPG42 | solute carrier family 33 member 1 |
| TCMBANKGE000298 | SOD1 | ALS; ALS1; HEL-S-44; IPOA; SOD; STAHP; hSod1; homodimer | superoxide dismutase 1 |
| TCMBANKGE014894 | NDRG2 | SYLD | NDRG family member 2 |
| TCMBANKGE011516 | SLC30A6 | MST103; MSTP103; ZNT6 | solute carrier family 30 member 6 |
| TCMBANKGE006434 | GBX2 | - | gastrulation brain homeobox 2 |
| TCMBANKGE010777 | DISC1 | C1orf136; SCZD9 | DISC1 scaffold protein |
| TCMBANKGE004842 | SRRM2 | 300-KD; CWF21; Cwc21; HSPC075; SRL300; SRm300 | serine/arginine repetitive matrix 2 |
| TCMBANKGE002024 | PSD3 | EFA6D; EFA6R; HCA67 | pleckstrin and Sec7 domain containing 3 |
| TCMBANKGE012920 | EPHA3 | EK4; ETK; ETK1; HEK; HEK4; TYRO4 | EPH receptor A3 |
| TCMBANKGE008921 | RXRA | NR2B1 | retinoid X receptor alpha |
| TCMBANKGE000364 | SMN1 | BCD541; GEMIN1; SMA; SMA1; SMA2; SMA3; SMA4; SMA@; SMN; SMNT; T-BCD541; TDRD16A | survival of motor neuron 1, telomeric |
| TCMBANKGE002022 | XRCC1 | RCC; SCAR26 | X-ray repair cross complementing 1 |
| TCMBANKGE014050 | GABRA1 | ECA4; EIEE19; EJM; EJM5 | gamma-aminobutyric acid type A receptor subunit alpha1 |
| TCMBANKGE000538 | CYP27A1 | CP27; CTX; CYP27 | cytochrome P450 family 27 subfamily A member 1 |
| TCMBANKGE013296 | UNC13A | Munc13-1 | unc-13 homolog A |
| TCMBANKGE012465 | FTO | ALKBH9; BMIQ14; GDFD | FTO alpha-ketoglutarate dependent dioxygenase |
| TCMBANKGE000589 | CD68 | GP110; LAMP4; SCARD1 | CD68 molecule |
| TCMBANKGE007141 | MTHFR | - | methylenetetrahydrofolate reductase |
| TCMBANKGE010035 | SLC25A12 | AGC1; ARALAR; EIEE39 | solute carrier family 25 member 12 |
| TCMBANKGE004254 | CSNK1E | CKIe; CKIepsilon; HCKIE | casein kinase 1 epsilon |
| TCMBANKGE009688 | MT1A | MT-1A; MT-IA; MT1; MT1S; MTC | metallothionein 1A |
| TCMBANKGE000271 | APOE | AD2; APO-E; ApoE4; LDLCQ5; LPG | apolipoprotein E |
| TCMBANKGE000017 | MAPT | DDPAC; FTDP-17; MAPTL; MSTD; MTBT1; MTBT2; PPND; PPP1R103; TAU | microtubule associated protein tau |
| TCMBANKGE007154 | KPNB1 | IMB1; IPO1; IPOB; Impnb; NTF97 | karyopherin subunit beta 1 |
| TCMBANKGE000842 | SLC18A2 | PKDYS2; SVAT; SVMT; VAT2; VMAT2 | solute carrier family 18 member A2 |
| TCMBANKGE000563 | CLU | AAG4; APO-J; APOJ; CLI; CLU1; CLU2; KUB1; NA1/NA2; SGP-2; SGP2; SP-40; TRPM-2; TRPM2 | clusterin |
| TCMBANKGE005229 | DPP6 | DPL1; DPPX; MRD33; VF2 | dipeptidyl peptidase like 6 |
| TCMBANKGE001680 | OLFM4 | GC1; GW112; OLM4; OlfD; UNQ362; bA209J19.1; hGC-1; hOLfD | olfactomedin 4 |
| TCMBANKGE003746 | CREBBP | CBP; KAT3A; MKHK1; RSTS; RSTS1 | CREB binding protein |
| TCMBANKGE002544 | IDI1 | IPP1; IPPI1 | isopentenyl-diphosphate delta isomerase 1 |
| TCMBANKGE013760 | SERPINA3 | AACT; ACT; GIG24; GIG25 | serpin family A member 3 |
| TCMBANKGE001169 | BCL2L1 | BCL-XL/S; BCL2L; BCLX; Bcl-X; PPP1R52 | BCL2 like 1 |
| TCMBANKGE010663 | MT1E | MT-1E; MT-IE; MT1; MTD | metallothionein 1E |
| TCMBANKGE012936 | MOBP | - | myelin associated oligodendrocyte basic protein |
| TCMBANKGE000280 | VIM | - | vimentin |
| TCMBANKGE009489 | ARHGEF28 | RGNEF; RIP2; p190RHOGEF | Rho guanine nucleotide exchange factor 28 |
| TCMBANKGE000436 | ERBB4 | ALS19; HER4; p180erbB4 | erb-b2 receptor tyrosine kinase 4 |
| TCMBANKGE002600 | FUS | ALS6; ETM4; FUS1; HNRNPP2; POMP75; TLS | FUS RNA binding protein |
| TCMBANKGE002043 | CTNND2 | GT24; NPRAP | catenin delta 2 |
| TCMBANKGE000221 | GRIA2 | GLUR2; GLURB; GluA2; GluR-K2; HBGR2; gluR-2; gluR-B | glutamate ionotropic receptor AMPA type subunit 2 |
| TCMBANKGE005851 | ALS2 | ALS2CR6; ALSJ; IAHSP; PLSJ | alsin Rho guanine nucleotide exchange factor ALS2 |
| TCMBANKGE012252 | OPCML | IGLON1; OBCAM; OPCM | opioid binding protein/cell adhesion molecule like |
| TCMBANKGE013334 | PON3 | - | paraoxonase 3 |
| TCMBANKGE003650 | METTL21A | FAM119A; HCA557b; HSPA-KMT | methyltransferase like 21A |
| TCMBANKGE001176 | CAT | - | catalase |
| TCMBANKGE010021 | CHGB | SCG1 | chromogranin B |
| TCMBANKGE005615 | HNRNPA3 | 2610510D13Rik; D10S102; FBRNP; HNRPA3 | heterogeneous nuclear ribonucleoprotein A3 |
| TCMBANKGE000758 | HSF1 | HSTF1 | heat shock transcription factor 1 |
| TCMBANKGE000889 | HFE | HFE1; HH; HLA-H; MVCD7; TFQTL2 | homeostatic iron regulator |
| TCMBANKGE014391 | SUGP1 | F23858; RBP; SF4 | SURP and G-patch domain containing 1 |
| TCMBANKGE000934 | GFAP | ALXDRD | glial fibrillary acidic protein |
| TCMBANKGE013409 | GSR | GR; GSRD; HEL-75; HEL-S-122m | glutathione-disulfide reductase |
| TCMBANKGE011407 | PDGFA | PDGF-A; PDGF1 | platelet derived growth factor subunit A |
| TCMBANKGE002751 | TMEM106B | HLD16 | transmembrane protein 106B |
| TCMBANKGE008019 | INA | NEF5; NF-66; TXBP-1 | internexin neuronal intermediate filament protein alpha |
| TCMBANKGE006553 | PON1 | ESA; MVCD5; PON | paraoxonase 1 |
| TCMBANKGE006216 | SETX | ALS4; AOA2; SCAN2; SCAR1; Sen1; bA479K20.2 | senataxin |
| TCMBANKGE008323 | NRXN3 | C14orf60 | neurexin 3 |
| TCMBANKGE010825 | NUP98 | ADIR2; NUP196; NUP96; Nup98-96 | nucleoporin 98 and 96 precursor |
| TCMBANKGE000729 | CASP1 | ICE; IL1BC; P45 | caspase 1 |
| TCMBANKGE001978 | GRM2 | GLUR2; GPRC1B; MGLUR2; mGlu2 | glutamate metabotropic receptor 2 |
| TCMBANKGE005037 | CALB2 | CAB29; CAL2; CR | calbindin 2 |
| TCMBANKGE010609 | UBQLN2 | ALS15; CHAP1; DSK2; HRIHFB2157; N4BP4; PLIC2 | ubiquilin 2 |
| TCMBANKGE000469 | CTSD | CLN10; CPSD; HEL-S-130P | cathepsin D |
| TCMBANKGE010270 | APEX1 | APE; APE1; APEN; APEX; APX; HAP1; REF1 | apurinic/apyrimidinic endodeoxyribonuclease 1 |
| TCMBANKGE000714 | SHC1 | SHC; SHCA | SHC adaptor protein 1 |
| TCMBANKGE012459 | PON2 | - | paraoxonase 2 |
| TCMBANKGE004986 | ANG | ALS9; HEL168; RAA1; RNASE4; RNASE5 | angiogenin |
| TCMBANKGE010859 | FMO1 | - | flavin containing dimethylaniline monoxygenase 1 |
| TCMBANKGE000988 | HGF | DFNB39; F-TCF; HGFB; HPTA; SF | hepatocyte growth factor |
| TCMBANKGE000240 | IL17A | CTLA-8; CTLA8; IL-17; IL-17A; IL17 | interleukin 17A |
| TCMBANKGE001200 | STMN1 | C1orf215; LAP18; Lag; OP18; PP17; PP19; PR22; SMN | stathmin 1 |
| TCMBANKGE003474 | GSX2 | DMJDS2; GSH2 | GS homeobox 2 |
| TCMBANKGE002728 | CNTF | HCNTF | ciliary neurotrophic factor |
| TCMBANKGE010583 | SMN2 | BCD541; C-BCD541; GEMIN1; SMNC; TDRD16B | survival of motor neuron 2, centromeric |
| TCMBANKGE003188 | P4HB | CLCRP1; DSI; ERBA2L; GIT; P4Hbeta; PDI; PDIA1; PHDB; PO4DB; PO4HB; PROHB | prolyl 4-hydroxylase subunit beta |
| TCMBANKGE006163 | ITPR2 | ANHD; CFAP48; INSP3R2; IP3R2 | inositol 1,4,5-trisphosphate receptor type 2 |
| TCMBANKGE011614 | IDI2 | IPPI2 | isopentenyl-diphosphate delta isomerase 2 |
| TCMBANKGE000828 | TREM2 | PLOSL2; TREM-2; Trem2a; Trem2b; Trem2c | triggering receptor expressed on myeloid cells 2 |
| TCMBANKGE011954 | TARDBP | ALS10; TDP-43 | TAR DNA binding protein |
| TCMBANKGE008393 | GRN | CLN11; GEP; GP88; PCDGF; PEPI; PGRN | granulin precursor |
| TCMBANKGE014814 | VPS54 | HCC8; PPP1R164; SLP-8p; VPS54L; WR; hVps54L | VPS54 subunit of GARP complex |
| TCMBANKGE010695 | ADARB1 | ADAR2; DRABA2; DRADA2; NEDHYMS; RED1 | adenosine deaminase RNA specific B1 |
| TCMBANKGE003016 | TLE3 | ESG; ESG3; GRG3; HsT18976 | TLE family member 3, transcriptional corepressor |
| TCMBANKGE008830 | JAK3 | JAK-3; JAK3_HUMAN; JAKL; L-JAK; LJAK | Janus kinase 3 |
| TCMBANKGE013936 | FGF6 | HBGF-6; HST2 | fibroblast growth factor 6 |
| TCMBANKGE001223 | SLC17A5 | AST; ISSD; NSD; SD; SIALIN; SIASD; SLD | solute carrier family 17 member 5 |
| TCMBANKGE014586 | CHRNG | ACHRG | cholinergic receptor nicotinic gamma subunit |
| TCMBANKGE002978 | RTN4R | NGR; NOGOR | reticulon 4 receptor |
| TCMBANKGE006831 | SLC9A9 | AUTS16; NHE9 | solute carrier family 9 member A9 |
| TCMBANKGE004382 | DNAAF1 | CILD13; DAU1; LRRC50; ODA7; swt | dynein axonemal assembly factor 1 |
| TCMBANKGE005214 | CCNF | FBX1; FBXO1 | cyclin F |
| TCMBANKGE004007 | CLVS1 | C6orf212L; CRALBPL; RLBP1L1 | clavesin 1 |
| TCMBANKGE000236 | BDNF | ANON2; BULN2 | brain derived neurotrophic factor |
| TCMBANKGE002661 | FGGY | - | FGGY carbohydrate kinase domain containing |
| TCMBANKGE013956 | DYNC1H1 | CMT2O; DHC1; DHC1a; DNCH1; DNCL; DNECL; DYHC; Dnchc1; HL-3; SMALED1; p22 | dynein cytoplasmic 1 heavy chain 1 |
| TCMBANKGE010103 | OPTN | ALS12; FIP2; GLC1E; HIP7; HYPL; NRP; TFIIIA-INTP | optineurin |
| TCMBANKGE008635 | SIX2 | - | SIX homeobox 2 |
| TCMBANKGE007674 | MAK16 | MAK16L; RBM13 | MAK16 homolog |
| TCMBANKGE006511 | PTBP1 | HNRNP-I; HNRNPI; HNRPI; PTB; PTB-1; PTB-T; PTB2; PTB3; PTB4; pPTB | polypyrimidine tract binding protein 1 |
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Dai SX Lab