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疾病ID:TCMBANKDI028619
疾病名:Leukocyte adhesion deficiency type 1
MeSH_Name:Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Immune System Diseases
HPO_Name:-
UMLS_Name:Disease or Syndrome
DO_Name:genetic disease; disease of anatomical entity
疾病类型:disease
DisGeNET_Link:C0398738
MeSH_Link:C16; C20
HPO_Link:-
UMLS_Link:T047
DO_Link:DOID:630; DOID:7
HERB_ID:-
疾病对应的植物
| ID | 拉丁名 | 药名 | 药用植物名 | 功能与主治 | 来源 | 药用部位 | 使用民族 |
|---|
疾病对应的化合物
| 化合物ID | 化合物名 | 别名 | 分子式 | 分子质量 | Smiles |
|---|
疾病对应的靶点
| 靶点ID | 基因名 | 基因别名 | 描述 |
|---|
| TCMBANKGE007370 | WWC1 | HBEBP3; HBEBP36; KIBRA; MEMRYQTL; PPP1R168 | WW and C2 domain containing 1 |
| TCMBANKGE010435 | COL17A1 | BA16H23.2; BP180; BPA-2; BPAG2; ERED; LAD-1 | collagen type XVII alpha 1 chain |
| TCMBANKGE001933 | FERMT3 | KIND3; MIG-2; MIG2B; UNC112C; URP2; URP2SF | fermitin family member 3 |
| TCMBANKGE011670 | ATP2C1 | ATP2C1A; BCPM; HHD; PMR1; SPCA1; hSPCA1 | ATPase secretory pathway Ca2+ transporting 1 |
| TCMBANKGE006975 | THBS1 | THBS; THBS-1; TSP; TSP-1; TSP1 | thrombospondin 1 |
| TCMBANKGE007029 | RABGEF1 | RABEX5; RAP1; rabex-5 | RAB guanine nucleotide exchange factor 1 |
| TCMBANKGE000171 | DNMT1 | ADCADN; AIM; CXXC9; DNMT; HSN1E; MCMT; m.HsaI | DNA methyltransferase 1 |
| TCMBANKGE000896 | SFRP1 | FRP; FRP-1; FRP1; FrzA; SARP2 | secreted frizzled related protein 1 |
| TCMBANKGE007041 | RAC2 | EN-7; Gx; HSPC022; p21-Rac2 | Rac family small GTPase 2 |
| TCMBANKGE000433 | IL37 | FIL1; FIL1(ZETA); FIL1Z; IL-1F7; IL-1H; IL-1H4; IL-1RP1; IL-37; IL1F7; IL1H4; IL1RP1 | interleukin 37 |
| TCMBANKGE000440 | HDAC1 | GON-10; HD1; KDAC1; RPD3; RPD3L1 | histone deacetylase 1 |
| TCMBANKGE011178 | COL4A5 | ASLN; ATS; ATS1; CA54 | collagen type IV alpha 5 chain |
| TCMBANKGE011702 | TNFRSF8 | CD30; D1S166E; Ki-1 | TNF receptor superfamily member 8 |
| TCMBANKGE000047 | AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | AKT serine/threonine kinase 1 |
| TCMBANKGE001013 | BIRC5 | API4; EPR-1 | baculoviral IAP repeat containing 5 |
| TCMBANKGE007678 | TUG1 | LINC00080; NCRNA00080; TI-227H | taurine up-regulated 1 |
| TCMBANKGE000305 | PIK3CD | APDS; IMD14; P110DELTA; PI3K; p110D | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta |
| TCMBANKGE001203 | MAPK1 | ERK; ERK-2; ERK2; ERT1; MAPK2; P42MAPK; PRKM1; PRKM2; p38; p40; p41; p41mapk; p42-MAPK | mitogen-activated protein kinase 1 |
| TCMBANKGE000477 | EZH2 | ENX-1; ENX1; EZH2b; KMT6; KMT6A; WVS; WVS2 | enhancer of zeste 2 polycomb repressive complex 2 subunit |
| TCMBANKGE001257 | RET | CDHF12; CDHR16; HSCR1; MEN2A; MEN2B; MTC1; PTC; RET-ELE1 | ret proto-oncogene |
| TCMBANKGE008994 | LAD1 | LadA | ladinin 1 |
| TCMBANKGE006832 | IGHG3 | IgG3 | immunoglobulin heavy constant gamma 3 (G3m marker) |
| TCMBANKGE001153 | EPHB2 | BDPLT22; CAPB; DRT; EK5; EPHT3; ERK; Hek5; PCBC; Tyro5 | EPH receptor B2 |
| TCMBANKGE006255 | SP1 | - | Sp1 transcription factor |
| TCMBANKGE005311 | DLC1 | ARHGAP7; HP; STARD12; p122-RhoGAP | DLC1 Rho GTPase activating protein |
| TCMBANKGE011668 | RAP1A | C21KG; G-22K; KREV-1; KREV1; RAP1; SMGP21 | RAP1A, member of RAS oncogene family |
| TCMBANKGE010148 | CKAP2L | - | cytoskeleton associated protein 2 like |
| TCMBANKGE000204 | CXCL8 | GCP-1; GCP1; IL8; LECT; LUCT; LYNAP; MDNCF; MONAP; NAF; NAP-1; NAP1; SCYB8 | C-X-C motif chemokine ligand 8 |
| TCMBANKGE000231 | MAP2K1 | CFC3; MAPKK1; MEK1; MKK1; PRKMK1 | mitogen-activated protein kinase kinase 1 |
| TCMBANKGE008838 | GOLM1 | C9orf155; GOLPH2; GP73; HEL46; PSEC0257; bA379P1.3 | golgi membrane protein 1 |
| TCMBANKGE001182 | SIRT1 | SIR2; SIR2L1; SIR2alpha | sirtuin 1 |
| TCMBANKGE000280 | VIM | - | vimentin |
| TCMBANKGE000587 | ITGAM | CD11B; CR3A; MAC-1; MAC1A; MO1A; SLEB6 | integrin subunit alpha M |
| TCMBANKGE001030 | NOTCH1 | AOS5; AOVD1; TAN1; hN1 | notch receptor 1 |
| TCMBANKGE000307 | PIK3CB | P110BETA; PI3K; PI3KBETA; PIK3C1 | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta |
| TCMBANKGE012411 | DDX3X | CAP-Rf; DBX; DDX14; DDX3; HLP2; MRX102; MRXSSB | DEAD-box helicase 3 X-linked |
| TCMBANKGE004346 | TERF2IP | DRIP5; RAP1 | TERF2 interacting protein |
| TCMBANKGE000787 | VCAM1 | CD106; INCAM-100 | vascular cell adhesion molecule 1 |
| TCMBANKGE008945 | TEAD4 | EFTR-2; RTEF1; TCF13L1; TEF-3; TEF3; TEFR-1; hRTEF-1B | TEA domain transcription factor 4 |
| TCMBANKGE003758 | SLC2A10 | ATORS; ATS; GLUT10 | solute carrier family 2 member 10 |
| TCMBANKGE001160 | CD274 | B7-H; B7H1; PD-L1; PDCD1L1; PDCD1LG1; PDL1; hPD-L1 | CD274 molecule |
| TCMBANKGE014404 | HMGA2 | BABL; HMGI-C; HMGIC; LIPO; STQTL9 | high mobility group AT-hook 2 |
| TCMBANKGE000729 | CASP1 | ICE; IL1BC; P45 | caspase 1 |
| TCMBANKGE011497 | SOX5 | L-SOX5; L-SOX5B; L-SOX5F; LAMSHF | SRY-box transcription factor 5 |
| TCMBANKGE001012 | FOXP3 | AIID; DIETER; IPEX; JM2; PIDX; XPID | forkhead box P3 |
| TCMBANKGE013662 | KLRK1 | CD314; D12S2489E; KLR; NKG2-D; NKG2D | killer cell lectin like receptor K1 |
| TCMBANKGE000251 | FGF2 | BFGF; FGF-2; FGFB; HBGF-2 | fibroblast growth factor 2 |
| TCMBANKGE000988 | HGF | DFNB39; F-TCF; HGFB; HPTA; SF | hepatocyte growth factor |
| TCMBANKGE001056 | KRAS | C-K-RAS; C-K-RAS; CFC2; K-RAS2A; K-RAS2B; K-RAS4A; K-RAS4B; K-Ras; K-Ras 2; KI-RAS; KRAS1; KRAS2; NS; NS3; OES; RALD; RASK2; c-Ki-ras; c-Ki-ras2 | KRAS proto-oncogene, GTPase |
| TCMBANKGE000646 | DECR1 | DECR; NADPH; SDR18C1 | 2,4-dienoyl-CoA reductase 1 |
| TCMBANKGE000240 | IL17A | CTLA-8; CTLA8; IL-17; IL-17A; IL17 | interleukin 17A |
| TCMBANKGE009492 | HOXA10 | HOX1; HOX1.8; HOX1H; PL | homeobox A10 |
| TCMBANKGE001732 | ITGAL | CD11A; LFA-1; LFA1A | integrin subunit alpha L |
| TCMBANKGE001102 | MIR21 | MIRN21; hsa-mir-21; miR-21; miRNA21 | microRNA 21 |
| TCMBANKGE000373 | ATG12 | APG12; APG12L; FBR93; HAPG12 | autophagy related 12 |
| TCMBANKGE012571 | MTSS1 | MIM; MIMA; MIMB | MTSS I-BAR domain containing 1 |
| TCMBANKGE000786 | MIR200A | MIRN200A; mir-200a | microRNA 200a |
| TCMBANKGE000397 | AXL | ARK; JTK11; Tyro7; UFO | AXL receptor tyrosine kinase |
| TCMBANKGE001027 | STK11 | LKB1; PJS; hLKB1 | serine/threonine kinase 11 |
| TCMBANKGE000306 | PIK3CG | PI3CG; PI3K; PI3Kgamma; PIK3; p110gamma; p120-PI3K | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma |
| TCMBANKGE000979 | KDR | CD309; FLK1; VEGFR; VEGFR2 | kinase insert domain receptor |
| TCMBANKGE000771 | TWIST1 | ACS3; BPES2; BPES3; CRS; CRS1; CSO; SCS; SWCOS; TWIST; bHLHa38 | twist family bHLH transcription factor 1 |
| TCMBANKGE011182 | ITGB2 | CD18; LAD; LCAMB; LFA-1; MAC-1; MF17; MFI7 | integrin subunit beta 2 |
| TCMBANKGE004600 | WNT5B | - | Wnt family member 5B |
| TCMBANKGE011315 | SKAP2 | PRAP; RA70; SAPS; SCAP2; SKAP-HOM; SKAP55R | src kinase associated phosphoprotein 2 |
| TCMBANKGE003918 | E2F3 | E2F-3 | E2F transcription factor 3 |
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Dai SX Lab