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疾病ID:TCMBANKDI029712
疾病名:Malignant neoplasm of large intestine
MeSH_Name:Digestive System Diseases; Neoplasms
HPO_Name:-
UMLS_Name:Neoplastic Process
DO_Name:disease of anatomical entity; disease of cellular proliferation
疾病类型:disease
DisGeNET_Link:C0346629
MeSH_Link:C06; C04
HPO_Link:-
UMLS_Link:T191
DO_Link:DOID:7; DOID:14566
HERB_ID:-
疾病对应的植物
| ID | 拉丁名 | 药名 | 药用植物名 | 功能与主治 | 来源 | 药用部位 | 使用民族 |
|---|
疾病对应的化合物
| 化合物ID | 化合物名 | 别名 | 分子式 | 分子质量 | Smiles |
|---|
疾病对应的靶点
| 靶点ID | 基因名 | 基因别名 | 描述 |
|---|
| TCMBANKGE003294 | TDP2 | AD022; EAP2; EAPII; TTRAP; dJ30M3.3; hTDP2 | tyrosyl-DNA phosphodiesterase 2 |
| TCMBANKGE000473 | TRPC6 | FSGS2; TRP6 | transient receptor potential cation channel subfamily C member 6 |
| TCMBANKGE001180 | SMAD3 | HSPC193; HsT17436; JV15-2; LDS1C; LDS3; MADH3 | SMAD family member 3 |
| TCMBANKGE000376 | CRTC3 | TORC-3; TORC3 | CREB regulated transcription coactivator 3 |
| TCMBANKGE003621 | ACTRT3 | ARP-T3; ARPM1 | actin related protein T3 |
| TCMBANKGE007792 | EPHA5 | CEK7; EHK-1; EHK1; EK7; HEK7; TYRO4 | EPH receptor A5 |
| TCMBANKGE014583 | RTEL1 | C20orf41; DKCA4; DKCB5; NHL; PFBMFT3; RTEL | regulator of telomere elongation helicase 1 |
| TCMBANKGE003804 | FGFR2 | BBDS; BEK; BFR-1; CD332; CEK3; CFD1; ECT1; JWS; K-SAM; KGFR; TK14; TK25 | fibroblast growth factor receptor 2 |
| TCMBANKGE006357 | FEN1 | FEN-1; MF1; RAD2 | flap structure-specific endonuclease 1 |
| TCMBANKGE002185 | BMP5 | - | bone morphogenetic protein 5 |
| TCMBANKGE006813 | TET2 | KIAA1546; MDS | tet methylcytosine dioxygenase 2 |
| TCMBANKGE000742 | SMAD7 | CRCS3; MADH7; MADH8 | SMAD family member 7 |
| TCMBANKGE007713 | LPAR1 | EDG2; GPR26; Gpcr26; LPA1; Mrec1.3; VZG1; edg-2; rec.1.3; vzg-1 | lysophosphatidic acid receptor 1 |
| TCMBANKGE005737 | MYNN | OSZF; SBBIZ1; ZBTB31; ZNF902 | myoneurin |
| TCMBANKGE010781 | BRCA2 | BRCC2; BROVCA2; FACD; FAD; FAD1; FANCD; FANCD1; GLM3; PNCA2; XRCC11 | BRCA2 DNA repair associated |
| TCMBANKGE009712 | TOX2 | C20orf100; GCX-1; GCX1; dJ1108D11.2; dJ495O3.1 | TOX high mobility group box family member 2 |
| TCMBANKGE003205 | WWOX | D16S432E; EIEE28; FOR; FRA16D; HHCMA56; PRO0128; SCAR12; SDR41C1; WOX1 | WW domain containing oxidoreductase |
| TCMBANKGE010717 | TUBA1C | TUBA6; bcm948 | tubulin alpha 1c |
| TCMBANKGE003924 | CCND2 | KIAK0002; MPPH3 | cyclin D2 |
| TCMBANKGE011565 | PPP1R21 | CCDC128; KLRAQ1 | protein phosphatase 1 regulatory subunit 21 |
| TCMBANKGE000962 | TFEB | ALPHATFEB; BHLHE35; TCFEB | transcription factor EB |
| TCMBANKGE003590 | SMAD9 | MADH6; MADH9; PPH2; SMAD8; SMAD8/9; SMAD8A; SMAD8B | SMAD family member 9 |
| TCMBANKGE009355 | ACOXL | - | acyl-CoA oxidase like |
| TCMBANKGE008180 | PREX1 | P-REX1 | phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1 |
| TCMBANKGE007397 | SH2B3 | IDDM20; LNK | SH2B adaptor protein 3 |
| TCMBANKGE000653 | TCF7L2 | TCF-4; TCF4 | transcription factor 7 like 2 |
| TCMBANKGE004515 | NXN | NRX; RRS2; TRG-4 | nucleoredoxin |
| TCMBANKGE005950 | FRY | 13CDNA73; 214K23.2; C13orf14; CG003; bA207N4.2; bA37E23.1 | FRY microtubule binding protein |
| TCMBANKGE001003 | LRIG1 | LIG-1; LIG1 | leucine rich repeats and immunoglobulin like domains 1 |
| TCMBANKGE004413 | EFCAB2 | CFAP200; DRC8 | EF-hand calcium binding domain 2 |
| TCMBANKGE005610 | MYO16 | MYAP3; MYR8; Myo16b; NYAP3; PPP1R107 | myosin XVI |
| TCMBANKGE001147 | CDH1 | Arc-1; BCDS1; CD324; CDHE; ECAD; LCAM; UVO | cadherin 1 |
| TCMBANKGE006149 | ZMIZ1 | MIZ; NEDDFSA; RAI17; TRAFIP10; ZIMP10 | zinc finger MIZ-type containing 1 |
| TCMBANKGE008132 | TMBIM1 | LFG3; MST100; MSTP100; PP1201; RECS1 | transmembrane BAX inhibitor motif containing 1 |
| TCMBANKGE000404 | ZFYVE9 | MADHIP; NSP; PPP1R173; SARA; SMADIP | zinc finger FYVE-type containing 9 |
| TCMBANKGE013806 | LAMA5 | - | laminin subunit alpha 5 |
| TCMBANKGE014664 | LIMA1 | EPLIN; LDLCQ8; SREBP3 | LIM domain and actin binding 1 |
| TCMBANKGE002603 | RAD51B | R51H2; RAD51L1; REC2 | RAD51 paralog B |
| TCMBANKGE012576 | SYMPK | SPK; SYM | symplekin |
| TCMBANKGE000986 | ERBB2 | CD340; HER-2; HER-2/neu; HER2; MLN 19; NEU; NGL; TKR1 | erb-b2 receptor tyrosine kinase 2 |
| TCMBANKGE012010 | LAMC1 | LAMB2 | laminin subunit gamma 1 |
| TCMBANKGE006608 | TMTC1 | ARG99; OLF; TMTC1A | transmembrane O-mannosyltransferase targeting cadherins 1 |
| TCMBANKGE013099 | SMAD6 | AOVD2; HsT17432; MADH6; MADH7 | SMAD family member 6 |
| TCMBANKGE005199 | NEK10 | CILD44 | NIMA related kinase 10 |
| TCMBANKGE011035 | DIP2B | - | disco interacting protein 2 homolog B |
| TCMBANKGE001037 | MMP2 | CLG4; CLG4A; MMP-2; MMP-II; MONA; TBE-1 | matrix metallopeptidase 2 |
| TCMBANKGE000645 | PIGU | CDC91L1; GAB1; GPIBD21; NEDBSS | phosphatidylinositol glycan anchor biosynthesis class U |
| TCMBANKGE007442 | NOTCH4 | INT3 | notch receptor 4 |
| TCMBANKGE009568 | SBF2 | CMT4B2; DENND7B; MTMR13 | SET binding factor 2 |
| TCMBANKGE014460 | RTEL1-TNFRSF6B | - | RTEL1-TNFRSF6B readthrough (NMD candidate) |
| TCMBANKGE011340 | ATF1 | EWS-ATF1; FUS/ATF-1; TREB36 | activating transcription factor 1 |
| TCMBANKGE004471 | RTN4 | ASY; NI220/250; NOGO; NSP; NSP-CL; Nbla00271; Nbla10545; RTN-X; RTN4-A; RTN4-B1; RTN4-B2; RTN4-C | reticulon 4 |
| TCMBANKGE003415 | GATA3 | HDR; HDRS | GATA binding protein 3 |
| TCMBANKGE003185 | HERC2 | D15F37S1; MRT38; SHEP1; jdf2; p528 | HECT and RLD domain containing E3 ubiquitin protein ligase 2 |
| TCMBANKGE000523 | BMP4 | BMP2B; BMP2B1; MCOPS6; OFC11; ZYME | bone morphogenetic protein 4 |
| TCMBANKGE008721 | SLCO2A1 | MATR1; OATP2A1; PGT; PHOAR2; SLC21A2 | solute carrier organic anion transporter family member 2A1 |
| TCMBANKGE002745 | TANC1 | ROLSB; TANC | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 |
| TCMBANKGE014340 | MACF1 | ABP620; ACF7; LIS9; MACF; OFC4 | microtubule actin crosslinking factor 1 |
| TCMBANKGE006345 | GREM1 | C15DUPq; CKTSF1B1; CRAC1; CRCS4; DAND2; DRM; DUP15q; GREMLIN; HMPS; HMPS1; IHG-2; MPSH; PIG2 | gremlin 1, DAN family BMP antagonist |
| TCMBANKGE013548 | SLC6A18 | Xtrp2 | solute carrier family 6 member 18 |
| TCMBANKGE000222 | EDN1 | ARCND3; ET1; HDLCQ7; PPET1; QME | endothelin 1 |
| TCMBANKGE005965 | CBLN2 | - | cerebellin 2 precursor |
| TCMBANKGE003989 | FMN1 | FMN; LD | formin 1 |
| TCMBANKGE000910 | SLC22A3 | EMT; EMTH; OCT3 | solute carrier family 22 member 3 |
| TCMBANKGE003732 | ERAP1 | A-LAP; ALAP; APPILS; ARTS-1; ARTS1; ERAAP; ERAAP1; PILS-AP; PILSAP | endoplasmic reticulum aminopeptidase 1 |
| TCMBANKGE003202 | DOCK3 | MOCA; NEDIDHA; PBP | dedicator of cytokinesis 3 |
| TCMBANKGE011054 | KCNIP4 | CALP; KCHIP4 | potassium voltage-gated channel interacting protein 4 |
| TCMBANKGE015031 | MZF1 | MZF-1; MZF1B; ZFP98; ZNF42; ZSCAN6 | myeloid zinc finger 1 |
| TCMBANKGE010414 | SPSB2 | GRCC9; SSB2 | splA/ryanodine receptor domain and SOCS box containing 2 |
| TCMBANKGE003855 | ZBTB20 | DPZF; HOF; ODA-8S; PRIMS; ZNF288 | zinc finger and BTB domain containing 20 |
| TCMBANKGE002245 | VTI1A | MMDS3; MVti1; VTI1RP2; Vti1-rp2 | vesicle transport through interaction with t-SNAREs 1A |
| TCMBANKGE009400 | GNAS | AHO; C20orf45; GNAS1; GPSA; GSA; GSP; NESP; PITA3; POH; SCG6; SgVI | GNAS complex locus |
| TCMBANKGE011619 | RTN1 | NSP | reticulon 1 |
| TCMBANKGE008722 | APC | BTPS2; DESMD; DP2; DP2.5; DP3; GS; PPP1R46 | APC regulator of WNT signaling pathway |
| TCMBANKGE006330 | ACTR1B | ARP1B; CTRN2; PC3 | actin related protein 1B |
| TCMBANKGE010969 | LRP1 | A2MR; APOER; APR; CD91; IGFBP-3R; IGFBP3R; IGFBP3R1; KPA; LRP; LRP1A; TGFBR5 | LDL receptor related protein 1 |
| TCMBANKGE007289 | CHD1 | CHD-1; PILBOS | chromodomain helicase DNA binding protein 1 |
| TCMBANKGE015038 | KRT8 | CARD2; CK-8; CK8; CYK8; K2C8; K8; KO | keratin 8 |
| TCMBANKGE002712 | POLD3 | P66; P68; PPP1R128 | DNA polymerase delta 3, accessory subunit |
| TCMBANKGE008123 | RNF4 | RES4-26; SLX5; SNURF | ring finger protein 4 |
| TCMBANKGE011634 | CDH3 | CDHP; HJMD; PCAD | cadherin 3 |
| TCMBANKGE011416 | CABLES2 | C20orf150; dJ908M14.2; ik3-2 | Cdk5 and Abl enzyme substrate 2 |
| TCMBANKGE006183 | SCAF8 | RBM16 | SR-related CTD associated factor 8 |
| TCMBANKGE005041 | CUBN | IFCR; IGS; IGS1; MGA1; gp280 | cubilin |
| TCMBANKGE012048 | HLA-B | AS; B-4901; HLAB | major histocompatibility complex, class I, B |
| TCMBANKGE011805 | KCNH1 | EAG; EAG1; Kv10.1; TMBTS; ZLS1; h-eag; hEAG; hEAG1 | potassium voltage-gated channel subfamily H member 1 |
| TCMBANKGE002440 | TBX3 | TBX3-ISO; UMS; XHL | T-box transcription factor 3 |
| TCMBANKGE004383 | PNKD | BRP17; DYT8; FKSG19; FPD1; KIPP1184; MR-1; MR-1S; MR1; PDC; PKND1; PNKD1; R1; TAHCCP2 | PNKD metallo-beta-lactamase domain containing |
| TCMBANKGE001045 | CCND1 | BCL1; D11S287E; PRAD1; U21B31 | cyclin D1 |
| TCMBANKGE000276 | NOS1 | IHPS1; N-NOS; NC-NOS; NOS; bNOS; nNOS | nitric oxide synthase 1 |
| TCMBANKGE005465 | FAM193A | C4orf8; RES4-22 | family with sequence similarity 193 member A |
| TCMBANKGE012900 | KLF5 | BTEB2; CKLF; IKLF | Kruppel like factor 5 |
| TCMBANKGE000931 | CYP17A1 | CPT7; CYP17; P450C17; S17AH | cytochrome P450 family 17 subfamily A member 1 |
| TCMBANKGE011135 | ZNF827 | - | zinc finger protein 827 |
| TCMBANKGE003972 | SPECC1 | CYTSB; HCMOGT-1; HCMOGT1; NSP | sperm antigen with calponin homology and coiled-coil domains 1 |
| TCMBANKGE010931 | HSPA12A | - | heat shock protein family A (Hsp70) member 12A |
| TCMBANKGE008732 | RNGTT | CAP1A; HCE; HCE1; hCAP | RNA guanylyltransferase and 5'-phosphatase |
| TCMBANKGE004338 | CLEC3A | CLECSF1 | C-type lectin domain family 3 member A |
| TCMBANKGE004792 | BICC1 | BICC; CYSRD | BicC family RNA binding protein 1 |
| TCMBANKGE005740 | TNS3 | TEM6; TENS1 | tensin 3 |
| TCMBANKGE002115 | HLA-F | CDA12; HLA-5.4; HLA-CDA12; HLAF | major histocompatibility complex, class I, F |
| TCMBANKGE013392 | BOC | CDON2 | BOC cell adhesion associated, oncogene regulated |
| TCMBANKGE001420 | SLC22A16 | CT2; FLIPT2; HEL-S-18; OAT6; OCT6; OKB1; dJ261K5.1 | solute carrier family 22 member 16 |
| TCMBANKGE002171 | RALY | HNRPCL2; P542 | RALY heterogeneous nuclear ribonucleoprotein |
| TCMBANKGE011627 | COL4A2 | BSVD2; ICH; POREN2 | collagen type IV alpha 2 chain |
| TCMBANKGE012034 | FADS2 | D6D; DES6; FADSD6; LLCDL2; SLL0262; TU13 | fatty acid desaturase 2 |
| TCMBANKGE012872 | BABAM1 | C19orf62; HSPC142; MERIT40; NBA1 | BRISC and BRCA1 A complex member 1 |
| TCMBANKGE006822 | HHIP | HIP | hedgehog interacting protein |
| TCMBANKGE009752 | BTBD9 | dJ322I12.1 | BTB domain containing 9 |
| TCMBANKGE009893 | GNG12 | - | G protein subunit gamma 12 |
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Dai SX Lab