Compound Summary


  Compound Information

药名:

Chelerythrine

别名:

34316-15-9 (Parent); CHEMBL1971693; 6471-86-9; Toddaline hydroxide; chelerythrine; [1,6-c]phenanthridinium, 1,2-dimethoxy-12-methyl-, hydroxide; SCHEMBL288916; UNII-65ML87R6OI; Chelerythrine aurichloride; AC1NS0S9; NSC76023; 1,2-dimethoxy-12-methyl-[1,3]benzodioxolo[5,6-c]phenanthridin-12-ium hydroxide; Toddalin hydroxide; Chelerythrinium hydroxide; NSC-76023; Chelerythrine, compd. with gold chloride (AuCl3); (1,3)Benzodioxolo(5,6-c)phenanthridinium, 1,2-dimethoxy-12-methyl-, hydroxide (9CI); Chelerythrine hydroxide; Helleritrine hydroxide; NSC 76023; 65ML87R6OI; 478-03-5

分子式:

C21H19NO5

Smiles:

C[N+]1=C2C(=C3C=CC(=C(C3=C1)OC)OC)C=CC4=CC5=C(C=C42)OCO5.[OH-]

成分:

HBIN020270

OB_score:

34.183773

SymMap_id:

SMIT04866;SMIT14630

TCMID_id:

3498

TCMSP_id:

MOL002666

PubChem_id:

5351594


   化合物对应的植物
植物ID 拉丁名 药用植物名 药名 来源 功能与主治 使用民族
TCMBANKHE003755 Radix Ampelopsis 白蔹 To remove toxic heat, to cure carbuncles, and to reduce nodules./Swelling toxin of sore and welling abscess, burns and scalds, scrofula, damp sore, warm malaria, frightepilepsy, blood dysentery, intestinal wind, hemorrhoids and fistulas, leukorrhea, knocks and falls, bleeding due to external injury.
TCMBANKHE003901 Argemone mexicana 蓟罂粟 To effuse sweat and disinhibit water, clear heat and resolve toxin, relieve pain and itch./Common cold without sweating, jaundice, strangury, edema, eyelid laceration, mounting qi , scab and lai, syphilis.
TCMBANKHE004459 Fructus Lycii 枸杞子 To benefit the liver and the kidney, to replenish vital essence and to improve eyesight./Lassitude in lumbus and knees, emission, dizziness and dim vision, lung disease with cough, diabetes mellitus.
TCMBANKHE004901 Dicentra spectabilis 荷包牡丹根 To dispel wind, quicken blood, settle pain./Incised wound, sore toxin, stomachache.
TCMBANKHE005000 Pericarpium Zanthoxyli 花椒 To warm the spleen and the stomach and relieve pain, to kill worms, and to relieve itching./Spleen-stomach vacuity cold, cold pain in stomach duct and abdomen, vomiting, diarrhea, abdominal pain and vomiting due to roundworm.
TCMBANKHE007245 Hylomecon japonica 荷青花 To dispel wind and free network vessels, dissipate stasis and disperse swelling./Wind-damp impediment pain, knocks and falls.
TCMBANKHE008052 Corydalis incisa 紫花鱼灯草 To resolve toxin and kill worms, relieve pain./Toxin swelling of sores, scab and lai, intractable lichen, eczema, poisonous snake bite.
TCMBANKHE006371 白屈菜 Pain in sensory nerve endings, pain from ulcer in digestive tract, stomachache, abdominal pain, enteritis, dysentery, chronic bronchitis, pertussis, cough, jaundice, edema, ascites, scab and lichen with swelling of sores, snake or insect bites.
TCMBANKHE006958 Papaver commutatum [Syn. Papaver rhoeas ] 丽春花 To suppress cough, settle pain, check diarrhea./Cough, migraine, abdominal pain, dysentery.
TCMBANKHE008360 Hypecoum leptocarpum 细果角茴香 To clear heat and resolve toxin, cool blood./Common cold with fever, headache, throat pain, red eyes with gall, pain in joints, pneumonia, hepatitis, cholecystitis, blood ejection, spontaneous external bleeding, hematochezia.
TCMBANKHE007829 Pericarpium Zanthoxyli 花椒 To warm the spleen and the stomach and relieve pain, to kill worms, and to relieve itching./Spleen-stomach vacuity cold, cold pain in stomach duct and abdomen, vomiting, diarrhea, abdominal pain and vomiting due to roundworm.
TCMBANKHE004238/YEM-1014 Phellodendron amurense;Cortex Phellodendri|Phellodendron chinense Schneid var.glabriusculum Schneid. 黄柏|秃叶黄蘗 广西黄柏 云南民族药物志:第五卷 1. To clear heat and dry dampness; 2. To reduce fire and release toxins/Damp-heat dysentery, tuberculosis, epidemic meningitis, acute conjunctivitis, trachoma, fever, abdominal pain, diarrhea, suppurative hematochezia, tenesmus, jaundice, yellow thick foul leukorrhagia, swelling pain in knees and feet, urinary tract infection, boil, sore, ulcer, eczema, mouth sore, hemorrhoids, burns, scalds, exuberance of fire with tidal fever, tidal fever with night sweat, emission. 瑶族/壮族
TCMBANKHE006216/YEM-234 Macleaya cordata|Macleaya cordata (Willd.)R. Br. 博落回 博落回 云南民族药物志:第二卷 To dispel wind, dissipate stasis, resolve toxin, relieve pain, kill worms./Ulcer of uterine cervix, carcinoma of uterine cervix, carcinoma of thyroid, swollen welling abscess and clove sores, ulcer of lower limb, hemorrhoids, eczema, snake or insect bites, painful swelling from knocks and falls, pain in joints due to rheumatalgia, decayed toothache, intractable lichen, trichomoniasis, brandy nose. 阿昌族/傣族/德昂族/景颇族/傈僳族/苗族/纳西族
TCMBANKHE005663/YNS-73/YEM-663 Toddalia asiatica|Toddalia asiatica (L.) Lam.|Toddalia asiatica(L.)Lam. 飞龙掌血 飞龙掌血茎|飞龙掌血 云南药材标准:第四册|云南民族药物志:第四卷 活血止痛,祛风散寒。用于胃脘疼痛;腰痛,寒湿痹痛,跌倒损伤;皮肤瘙痒|To dispel wind and relieve pain, stanch bleeding and dissipate stasis./Wind-damp Pain, stomachache, knocks and falls, blood ejection, spontaneous external bleeding, knife wound, amenorrhea, dysmenorrhea. 阿昌族/布依族/傣族/德昂族/哈尼族/基诺族/景颇族/拉祜族/傈僳族/苗族/佤族/瑶族/彝族/壮族

   植物对应的疾病
疾病ID 病名 疾病类型 MeSH 参考文献
TCMBANKDI000088 Lung Neoplasms group Neoplasms; Respiratory Tract Diseases 28288416

   化合物对应的靶点
靶点ID 基因名 基因别名 描述
TCMBANKGE000727 MAP1LC3A ATG8E; LC3; LC3A; MAP1ALC3; MAP1BLC3 microtubule associated protein 1 light chain 3 alpha
TCMBANKGE001198 BECN1 ATG6; VPS30; beclin1 beclin 1