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靶点ID:TCMBANKGE000727

靶点别名:ATG8E; LC3; LC3A; MAP1ALC3; MAP1BLC3

靶点描述:microtubule associated protein 1 light chain 3 alpha

染色体:20

染色体位置:20q11.22

靶点类型:protein-coding

HERB_ID:-

HGNC_Link:6838

OMIM_Link:601242

Ensembl_Link:ENSG00000101460

靶点对应的植物

ID	拉丁名	药名	药用植物名	功能与主治	来源	药用部位	使用民族

TCMBANKHE003732	Ganoderma Lucidum seu Japonicum		灵芝(赤芝）	Hyperlipemia, coronary heart disease, angina pectoris, septicemia, carcinoma, hepatitis, vacuity taxation, palpitation, insomnia, dizziness, fatigue hypodynamia, enduring cough and asthma, chronic bronchitis, silicosis.		dried sporocarp

靶点对应的化合物

化合物ID	化合物名	别名	分子式	分子质量	Smiles

TCMBANKIN000047	Chelerythrine	34316-15-9 (Parent); CHEMBL1971693; 6471-86-9; Toddaline hydroxide; chelerythrine; [1,6-c]phenanthridinium, 1,2-dimethoxy-12-methyl-, hydroxide; SCHEMBL288916; UNII-65ML87R6OI; Chelerythrine aurichloride; AC1NS0S9; NSC76023; 1,2-dimethoxy-12-methyl-[1,3]benzodioxolo[5,6-c]phenanthridin-12-ium hydroxide; Toddalin hydroxide; Chelerythrinium hydroxide; NSC-76023; Chelerythrine, compd. with gold chloride (AuCl3); (1,3)Benzodioxolo(5,6-c)phenanthridinium, 1,2-dimethoxy-12-methyl-, hydroxide (9CI); Chelerythrine hydroxide; Helleritrine hydroxide; NSC 76023; 65ML87R6OI; 478-03-5	C21H19NO5	365.4 g/mol	C[N+]1=C2C(=C3C=CC(=C(C3=C1)OC)OC)C=CC4=CC5=C(C=C42)OCO5.[OH-]
TCMBANKIN000065	dioscin	LMST01080053; C08897; 3-O-(Rhaa1-4(Rhaa1-2)Glcb)-(25R)-spirost-5-en-3beta-ol; dioscin ; 19057-60-4; Dioscin	C45H72O16	869.04	CC1CCC2(C(C3C(O2)CC4C3(CCC5C4CC=C6C5(CCC(C6)OC7C(C(C(C(O7)CO)OC8C(C(C(C(O8)C)O)O)O)O)OC9C(C(C(C(O9)C)O)O)O)C)C)C)OC1
TCMBANKIN000085	CUCURBITACIN I	JSI-124; cucurbitacin i	C14H9NO2	223.23	CC1(C2=CCC3C4(CC(C(C4(CC(=O)C3(C2C=C(C1=O)O)C)C)C(C)(C(=O)C=CC(C)(C)O)O)O)C)C
TCMBANKIN057931	DMR	CHEBI:30796; 02300_FLUKA; Malic acid, L(+)-; L(+)-Malic acid; C00497; InChI=1/C4H6O5/c5-2(4(8)9)1-3(6)7/h2,5H,1H2,(H,6,7)(H,8,9; butanedioic acid, 2-hydroxy-; (R)-()-2-Hydroxysuccinic acid; (2R)-2-hydroxysuccinic acid; D-()-Malic acid; D-Hydroxybutanedioic acid; EINECS 211-262-2; (R)-malic acid; Malic acid D-(+)-form; 2-HYDROXY-SUCCINIC ACID; MLS000069520; (2R)-2-hydroxybutanedioic acid; 46940U_SUPELCO; SMR000058580; (+)-D-malic acid; Malic acid, D-; R-malic acid; D- malic acid	C4H6O5	134.09 g/mol	C(C(C(=O)O)O)C(=O)O
TCMBANKIN059258	dihydrocapsacine	Dihydrocapsaicin; CHEBI:46932; Nonanamide, 8-methyl-N-vanillyl-; ZINC02522581; A813700; M1022_SIGMA; N-[(4-Hydroxy-3-methoxy-phenyl)methyl]-8-methyl-nonanamide; N-(4-hydroxy-3-methoxybenzyl)-8-methylnonanamide; N-[(3-methoxy-4-oxidanyl-cyclohexa-2,4-dien-1-yl)methyl]-8-methyl-non-6-enamide; NCGC00094119-02; TNP00314; ST057532; dihydrocapsaicin; 19408-84-5; 6,7-Dihydrocapsaicin; EU-0100782; NCGC00015645-01; N-(4-hydroxy-3-methoxy-benzyl)-8-methyl-pelargonamide; N-[(4-hydroxy-3-methoxy-1-cyclohexa-2,4-dienyl)methyl]-8-methyl-6-nonenamide; 8-Methyl-N-vanillylnonanamide; N-((4-Hydroxy-3-methoxyphenyl)methyl)-8-methylnonanamide; BRN 2815150; Dihydrocapsacine; Nonanamide, N-((4-hydroxy-3-methoxyphenyl)methyl)-8-methyl- (9CI); Lopac0_000782; N-[(4-hydroxy-3-methoxyphenyl)methyl]-8-methylnonanamide; NCGC00015645-02; Lopac-M-1022; CCRIS 1589	C18H29NO3	307.4 g/mol	CC(C)CCCCCCC(=O)NCC1=CC(=C(C=C1)O)OC
TCMBANKIN059675	rottlerin		C30H28O8	516.5 g/mol	CC1=C(C(=C(C(=C1O)C(=O)C)O)CC2=C(C(=C3C(=C2O)C=CC(O3)(C)C)C(=O)C=CC4=CC=CC=C4)O)O
TCMBANKIN060497	dioscin		C45H72O16	869.04	CC1CCC2(C(C3C(O2)CC4C3(CCC5C4CC=C6C5(CCC(C6)OC7C(C(C(C(O7)CO)OC8C(C(C(C(O8)C)O)O)O)O)OC9C(C(C(C(O9)C)O)O)O)C)C)C)OC1

靶点对应的疾病

疾病ID	疾病名	MeSH名	HPO名	UMLS名	疾病类型

TCMBANKDI000002		Pathological Conditions, Signs and Symptoms; Nervous System Diseases	Abnormality of the nervous system	Sign or Symptom	phenotype
TCMBANKDI000054		Nervous System Diseases; Mental Disorders	Abnormality of the nervous system	Disease or Syndrome	disease
TCMBANKDI000076		Neoplasms	-	Neoplastic Process	group
TCMBANKDI000891		Neoplasms; Respiratory Tract Diseases	Neoplasm; Abnormality of the respiratory system	Neoplastic Process	disease
TCMBANKDI003248		Nutritional and Metabolic Diseases; Endocrine System Diseases	Abnormality of metabolism/homeostasis; Abnormality of the endocrine system	Disease or Syndrome	disease
TCMBANKDI003733		Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Cardiovascular Diseases	Abnormality of the nervous system; Abnormality of blood and blood-forming tissues; Abnormality of the cardiovascular system	Pathologic Function	phenotype
TCMBANKDI006641		Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases	-	Pathologic Function	phenotype
TCMBANKDI007782		Neoplasms	-	Neoplastic Process	disease
TCMBANKDI008154		Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases	-	Neoplastic Process	disease
TCMBANKDI012119		Pathological Conditions, Signs and Symptoms	Abnormality of the nervous system	Cell or Molecular Dysfunction	phenotype
TCMBANKDI017024		Neoplasms; Respiratory Tract Diseases	-	Neoplastic Process	disease
TCMBANKDI023938		Neoplasms	-	Neoplastic Process	disease
TCMBANKDI024535		Neoplasms; Respiratory Tract Diseases	Neoplasm; Abnormality of the respiratory system	Neoplastic Process	disease
TCMBANKDI025420		Digestive System Diseases; Neoplasms	Abnormality of the digestive system; Neoplasm	Neoplastic Process	disease
TCMBANKDI026360		Infections	-	Disease or Syndrome	disease
TCMBANKDI027026		Neoplasms; Skin and Connective Tissue Diseases	-	Neoplastic Process	disease
TCMBANKDI031189		Neoplasms	Neoplasm; Abnormality of the respiratory system	Neoplastic Process	disease