Compound Summary

  Compound Information

TCMBANKIN000078

药名:	silymarin
别名:	AC-20318; AKOS015965311; silymarin
分子式:	C25H22O10
Smiles:	COC1=C(C=CC(=C1)C2C(OC3=C(O2)C=C(C=C3)C4C(C(=O)C5=C(C=C(C=C5O4)O)O)O)CO)O
成分:	HBIN044040
SymMap_id:	SMIT18310
TCMID_id:	23141
PubChem_id:	24832061

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   化合物对应的植物

植物ID	拉丁名	药用植物名	药名	来源	功能与主治	使用民族

TCMBANKHE001911	Herba Acalyphae	铁苋菜			1. Treatment of diarrhea and dysentery of darnpness-heat type. Recently, also for amebic dysentery and typhoid fever. 2. Treatment of hemoptysis, hematemesis, hemafecia, metrorrhagia, etc. 3. Treatment of dyspneic cough of lung-heat type./1. Bacteriostatic. 2. Astringent and protective on intestinal mucosa. 3. Antiasthmatic.
TCMBANKHE001959		白花水飞蓟
TCMBANKHE006366	Radix Moghaniae Philippinensis	千斤拔
TCMBANKHE006357		水飞蓟			Acute hepatitis, chronic hepatitis, cirrhosis, fatty liver, gallstones, cholangitis.
TCMBANKHE001493/XU-632	Folium Pini|Pinus massoniana	松针|马尾松		吉林省白山市抚松县	1. To tranquilize the mind. For palpitation, insomnia, amnesia. Recently used for neurasthenia, chronic Keshan disease, hypertension, coronary heart diseases and cor pulmonale. 2. External use for depriving dampness, killing parasite and alleviate itching. For exudative dermatitis, scabies and tinea./1. To tranquilize the mind. For palpitation, insomnia, amnesia. Recently used for neurasthenia, chronic Keshan disease, hypertension, coronary heart diseases and cor pulmonale. 2. External use for depriving dampness, killing parasite and alleviate itching

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   植物对应的疾病

疾病ID	病名	疾病类型	MeSH	参考文献

TCMBANKDI000019	Parkinson Disease	disease	Nervous System Diseases	20964710
TCMBANKDI000026	Obesity	disease	Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases	28625483
TCMBANKDI000081	Diabetes Mellitus, Experimental	disease	Nutritional and Metabolic Diseases; Endocrine System Diseases	20578796
TCMBANKDI000085	Inflammation	phenotype	Pathological Conditions, Signs and Symptoms	20578796
TCMBANKDI002231	Cholestasis	disease	Digestive System Diseases	24819445
TCMBANKDI006257	Biliary cirrhosis	disease	Pathological Conditions, Signs and Symptoms; Digestive System Diseases	24819445
TCMBANKDI012770	Altitude Sickness	phenotype	Respiratory Tract Diseases	27105952
TCMBANKDI013453	Proteinuria	phenotype	Pathological Conditions, Signs and Symptoms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases	22770926
TCMBANKDI023555	Hypoxia	phenotype	Pathological Conditions, Signs and Symptoms	27105952

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   化合物对应的靶点

靶点ID	基因名	基因别名	描述

TCMBANKGE000051	IL1B	IL-1; IL1-BETA; IL1F2; IL1beta	interleukin 1 beta
TCMBANKGE000052	TNF	DIF; TNF-alpha; TNFA; TNFSF2; TNLG1F	tumor necrosis factor
TCMBANKGE000199	ICAM1	BB2; CD54; P3.58	intercellular adhesion molecule 1
TCMBANKGE000204	CXCL8	GCP-1; GCP1; IL8; LECT; LUCT; LYNAP; MDNCF; MONAP; NAF; NAP-1; NAP1; SCYB8	C-X-C motif chemokine ligand 8
TCMBANKGE000298	SOD1	ALS; ALS1; HEL-S-44; IPOA; SOD; STAHP; hSod1; homodimer	superoxide dismutase 1
TCMBANKGE000315	IL4	BCGF-1; BCGF1; BSF-1; BSF1; IL-4	interleukin 4
TCMBANKGE000360	CCNA2	CCN1; CCNA	cyclin A2
TCMBANKGE000697	APAF1	APAF-1; CED4	apoptotic peptidase activating factor 1
TCMBANKGE000788	SELE	CD62E; ELAM; ELAM1; ESEL; LECAM2	selectin E
TCMBANKGE000921	CCNB1	CCNB	cyclin B1
TCMBANKGE001008	CYP3A4	CP33; CP34; CYP3A; CYP3A3; CYPIIIA3; CYPIIIA4; HLP; NF-25; P450C3; P450PCN1	cytochrome P450 family 3 subfamily A member 4
TCMBANKGE001013	BIRC5	API4; EPR-1	baculoviral IAP repeat containing 5
TCMBANKGE001045	CCND1	BCL1; D11S287E; PRAD1; U21B31	cyclin D1
TCMBANKGE001069	MPO	-	myeloperoxidase
TCMBANKGE001073	PTGS2	COX-2; COX2; GRIPGHS; PGG/HS; PGHS-2; PHS-2; hCox-2	prostaglandin-endoperoxide synthase 2
TCMBANKGE001085	MAPK8	JNK; JNK-46; JNK1; JNK1A2; JNK21B1/2; PRKM8; SAPK1; SAPK1c	mitogen-activated protein kinase 8
TCMBANKGE001132	BAX	BCL2L4	BCL2 associated X, apoptosis regulator
TCMBANKGE001148	VEGFA	MVCD1; VEGF; VPF	vascular endothelial growth factor A
TCMBANKGE001156	CASP3	CPP32; CPP32B; SCA-1	caspase 3
TCMBANKGE001161	IL2	IL-2; TCGF; lymphokine	interleukin 2
TCMBANKGE001166	BCL2	Bcl-2; PPP1R50	BCL2 apoptosis regulator
TCMBANKGE001169	BCL2L1	BCL-XL/S; BCL2L; BCLX; Bcl-X; PPP1R52	BCL2 like 1
TCMBANKGE001176	CAT	-	catalase
TCMBANKGE001182	SIRT1	SIR2; SIR2L1; SIR2alpha	sirtuin 1
TCMBANKGE001184	RELA	CMCU; NFKB3; p65	RELA proto-oncogene, NF-kB subunit
TCMBANKGE003210	POLD1	CDC2; CRCS10; MDPL; POLD	DNA polymerase delta 1, catalytic subunit
TCMBANKGE004731	ABCB5	ABCB5alpha; ABCB5beta; EST422562	ATP binding cassette subfamily B member 5
TCMBANKGE006248	FCER2	BLAST-2; CD23; CD23A; CLEC4J; FCE2; IGEBF	Fc fragment of IgE receptor II
TCMBANKGE006368	UGT1A1	BILIQTL1; GNT1; HUG-BR1; UDPGT; UDPGT 1-1; UGT1; UGT1A	UDP glucuronosyltransferase family 1 member A1
TCMBANKGE008786	CRAT	CAT; CAT1; NBIA8	carnitine O-acetyltransferase
TCMBANKGE009361	GPT	AAT1; ALT1; GPT1	glutamic--pyruvic transaminase
TCMBANKGE012906	PCDHAC2	PCDH-ALPHA-C2	protocadherin alpha subfamily C, 2
TCMBANKGE012983	CSNK1A1	CK1; CK1a; CKIa; HEL-S-77p; HLCDGP1; PRO2975	casein kinase 1 alpha 1