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疾病ID:TCMBANKDI006257

疾病名:Biliary cirrhosis

MeSH_Name:Pathological Conditions, Signs and Symptoms; Digestive System Diseases

HPO_Name:Abnormality of the digestive system

UMLS_Name:Disease or Syndrome

DO_Name:disease of anatomical entity

疾病类型:disease

DisGeNET_Link:C0023892

MeSH_Link:C23; C06

HPO_Link:HP:0025031

UMLS_Link:T047

DO_Link:DOID:7

HERB_ID:HBDIS001767

   疾病对应的植物
ID 拉丁名 药名 药用植物名 功能与主治 来源 药用部位 使用民族
   疾病对应的化合物
化合物ID 化合物名 别名 分子式 分子质量 Smiles
TCMBANKIN000078 silymarin AC-20318; AKOS015965311; silymarin C25H22O10 482.4 g/mol COC1=C(C=CC(=C1)C2C(OC3=C(O2)C=C(C=C3)C4C(C(=O)C5=C(C=C(C=C5O4)O)O)O)CO)O
   疾病对应的靶点
靶点ID 基因名 基因别名 描述
TCMBANKGE014935 ELF1 EFTUD1; RIA1 E74 like ETS transcription factor 1
TCMBANKGE000607 CD80 B7; B7-1; B7.1; BB1; CD28LG; CD28LG1; LAB7 CD80 molecule
TCMBANKGE008366 RPS6KA4 MSK2; RSK-B; S6K-alpha-4 ribosomal protein S6 kinase A4
TCMBANKGE000250 CCL5 D17S136E; RANTES; SCYA5; SIS-delta; SISd; TCP228; eoCP C-C motif chemokine ligand 5
TCMBANKGE014824 TNFSF15 TL1; TL1A; TNLG1B; VEGI; VEGI192A TNF superfamily member 15
TCMBANKGE000070 CAV1 BSCL3; CGL3; LCCNS; MSTP085; PPH3; VIP21 caveolin 1
TCMBANKGE015178 DAG1 156DAG; A3a; AGRNR; DAG; LGMDR16; MDDGA9; MDDGC7; MDDGC9 dystroglycan 1
TCMBANKGE000053 NFKB1 CVID12; EBP-1; KBF1; NF-kB; NF-kB1; NF-kappa-B1; NF-kappaB; NF-kappabeta; NFKB-p105; NFKB-p50; NFkappaB nuclear factor kappa B subunit 1
TCMBANKGE000452 CFTR ABC35; ABCC7; CF; CFTR/MRP; MRP7; TNR-CFTR; dJ760C5.1 CF transmembrane conductance regulator
TCMBANKGE000192 CDH5 7B4; CD144 cadherin 5
TCMBANKGE006572 GNLY D2S69E; LAG-2; LAG2; NKG5; TLA519 granulysin
TCMBANKGE000395 CXCL9 CMK; Humig; MIG; SCYB9; crg-10 C-X-C motif chemokine ligand 9
TCMBANKGE000162 MMP13 CLG3; MANDP1; MDST; MMP-13 matrix metallopeptidase 13
TCMBANKGE000955 ABCC2 ABC30; CMOAT; DJS; MRP2; cMRP ATP binding cassette subfamily C member 2
TCMBANKGE008380 IRF5 SLEB10 interferon regulatory factor 5
TCMBANKGE000229 ACE2 ACEH angiotensin I converting enzyme 2
TCMBANKGE008314 IKZF3 AIO; AIOLOS; ZNFN1A3 IKAROS family zinc finger 3
TCMBANKGE013066 NUP210 GP210; POM210 nucleoporin 210
TCMBANKGE001017 IDO1 IDO; IDO-1; INDO indoleamine 2,3-dioxygenase 1
TCMBANKGE002377 CXCR5 BLR1; CD185; MDR15 C-X-C motif chemokine receptor 5
TCMBANKGE001074 ATM AT1; ATA; ATC; ATD; ATDC; ATE; TEL1; TELO1 ATM serine/threonine kinase
TCMBANKGE000266 DCTN4 DYN4; P62 dynactin subunit 4
TCMBANKGE000534 SLC51B OSTB; OSTBETA solute carrier family 51 subunit beta
TCMBANKGE000294 CDKN1A CAP20; CDKN1; CIP1; MDA-6; P21; SDI1; WAF1; p21CIP1 cyclin dependent kinase inhibitor 1A
TCMBANKGE009048 PTPN22 LYP; LYP1; LYP2; PEP; PTPN22.5; PTPN22.6; PTPN8 protein tyrosine phosphatase non-receptor type 22
TCMBANKGE000205 NOS2 HEP-NOS; INOS; NOS; NOS2A nitric oxide synthase 2
TCMBANKGE008904 SLC51A OSTA; OSTalpha solute carrier family 51 subunit alpha
TCMBANKGE000201 ESR1 ER; ESR; ESRA; ESTRR; Era; NR3A1 estrogen receptor 1
TCMBANKGE002603 RAD51B R51H2; RAD51L1; REC2 RAD51 paralog B
TCMBANKGE009475 NAB1 - NGFI-A binding protein 1
TCMBANKGE004935 FCGR2A CD32; CD32A; CDw32; FCG2; FCGR2; FCGR2A1; FcGR; IGFR2 Fc fragment of IgG receptor IIa
TCMBANKGE001184 RELA CMCU; NFKB3; p65 RELA proto-oncogene, NF-kB subunit
TCMBANKGE001066 STAT4 SLEB11 signal transducer and activator of transcription 4
TCMBANKGE000721 LOXL2 LOR; LOR2; WS9-14 lysyl oxidase like 2
TCMBANKGE014647 IL7R CD127; CDW127; IL-7R-alpha; IL7RA; ILRA interleukin 7 receptor
TCMBANKGE006914 DCDC2 DCDC2A; DFNB66; NPHP19; NSC; RU2; RU2S doublecortin domain containing 2
TCMBANKGE001107 NOS3 ECNOS; eNOS nitric oxide synthase 3
TCMBANKGE003249 KRT7 CK7; K2C7; K7; SCL keratin 7
TCMBANKGE000663 AQP4 MIWC; WCH4 aquaporin 4
TCMBANKGE001037 MMP2 CLG4; CLG4A; MMP-2; MMP-II; MONA; TBE-1 matrix metallopeptidase 2
TCMBANKGE001126 NFE2L2 HEBP1; IMDDHH; NRF2; Nrf-2 nuclear factor, erythroid 2 like 2
TCMBANKGE014996 POU2AF1 BOB1; OBF-1; OBF1; OCAB POU class 2 homeobox associating factor 1
TCMBANKGE002009 PDHX DLDBP; E3BP; OPDX; PDHXD; PDX1; proX pyruvate dehydrogenase complex component X
TCMBANKGE000199 ICAM1 BB2; CD54; P3.58 intercellular adhesion molecule 1
TCMBANKGE006445 NPHP3 CFAP31; MKS7; NPH3; RHPD; RHPD1; SLSN3 nephrocystin 3
TCMBANKGE005560 DBT BCATE2; BCKAD-E2; BCKADE2; BCOADC-E2; E2; E2B dihydrolipoamide branched chain transacylase E2
TCMBANKGE000877 ABCG2 ABC15; ABCP; BCRP; BCRP1; BMDP; CD338; CDw338; EST157481; GOUT1; MRX; MXR; MXR-1; MXR1; UAQTL1 ATP binding cassette subfamily G member 2 (Junior blood group)
TCMBANKGE001097 HIF1A HIF-1-alpha; HIF-1A; HIF-1alpha; HIF1; HIF1-ALPHA; MOP1; PASD8; bHLHe78 hypoxia inducible factor 1 subunit alpha
TCMBANKGE001178 STAT3 ADMIO; ADMIO1; APRF; HIES signal transducer and activator of transcription 3
TCMBANKGE010809 ABCB4 ABC21; GBD1; ICP3; MDR2; MDR2/3; MDR3; PFIC-3; PGY3 ATP binding cassette subfamily B member 4
TCMBANKGE000297 JAK2 JTK10; THCYT3 Janus kinase 2
TCMBANKGE004047 PDE5A CGB-PDE; CN5A; PDE5 phosphodiesterase 5A
TCMBANKGE001202 MAPK14 CSBP; CSBP1; CSBP2; CSPB1; EXIP; Mxi2; PRKM14; PRKM15; RK; SAPK2A; p38; p38ALPHA mitogen-activated protein kinase 14
TCMBANKGE011387 CYGB HGB; STAP cytoglobin
TCMBANKGE000224 AGT ANHU; SERPINA8; hFLT1 angiotensinogen
TCMBANKGE007368 GSTP1 DFN7; FAEES3; GST3; GSTP; HEL-S-22; PI glutathione S-transferase pi 1
TCMBANKGE001158 LEP LEPD; OB; OBS leptin
TCMBANKGE001311 CAV2 CAV caveolin 2
TCMBANKGE004420 CLEC16A Gop-1; KIAA0350 C-type lectin domain containing 16A
TCMBANKGE000227 BMI1 FLVI2/BMI1; PCGF4; RNF51; flvi-2/bmi-1 BMI1 proto-oncogene, polycomb ring finger
TCMBANKGE000273 LOX AAT10 lysyl oxidase
TCMBANKGE000394 CXCR3 CD182; CD183; CKR-L2; CMKAR3; GPR9; IP10-R; Mig-R; MigR C-X-C motif chemokine receptor 3
TCMBANKGE000222 EDN1 ARCND3; ET1; HDLCQ7; PPET1; QME endothelin 1
TCMBANKGE002445 GHRL MTLRP ghrelin and obestatin prepropeptide
TCMBANKGE011602 DENND1B C1ORF18; C1orf218; FAM31B DENN domain containing 1B
TCMBANKGE013771 FBXL20 Fbl2; Fbl20 F-box and leucine rich repeat protein 20
TCMBANKGE000428 SERPINA1 A1A; A1AT; AAT; PI; PI1; PRO2275; alpha1AT; nNIF serpin family A member 1
TCMBANKGE001188 CXCL10 C7; IFI10; INP10; IP-10; SCYB10; crg-2; gIP-10; mob-1 C-X-C motif chemokine ligand 10
TCMBANKGE010437 ENTPD2 CD39L1; NTPDase-2 ectonucleoside triphosphate diphosphohydrolase 2
TCMBANKGE001109 ALPP ALP; ALPI; IAP; PALP; PLAP; PLAP-1 alkaline phosphatase, placental
TCMBANKGE001011 TNFSF10 APO2L; Apo-2L; CD253; TL2; TNLG6A; TRAIL TNF superfamily member 10
TCMBANKGE002000 CTLA4 ALPS5; CD; CD152; CELIAC3; CTLA-4; GRD4; GSE; IDDM12 cytotoxic T-lymphocyte associated protein 4
TCMBANKGE001149 PPARGC1A LEM6; PGC-1(alpha); PGC-1alpha; PGC-1v; PGC1; PGC1A; PPARGC1 PPARG coactivator 1 alpha
TCMBANKGE008826 LBR C14SR; DHCR14B; LMN2R; PHA; PHASK; TDRD18 lamin B receptor
TCMBANKGE005662 ALB HSA; PRO0883; PRO0903; PRO1341 albumin
TCMBANKGE000390 ABCC4 MOAT-B; MOATB; MRP4 ATP binding cassette subfamily C member 4
TCMBANKGE009742 HLA-DRB1 DRB1; HLA-DR1B; HLA-DRB; SS1 major histocompatibility complex, class II, DR beta 1
TCMBANKGE007582 ELMO1 CED-12; CED12; ELMO-1 engulfment and cell motility 1
TCMBANKGE012101 GOT1 AST1; ASTQTL1; GIG18; cAspAT; cCAT glutamic-oxaloacetic transaminase 1
TCMBANKGE006724 REN HNFJ2 renin
TCMBANKGE010737 MMEL1 MMEL2; NEP2; NEPII; NL1; NL2; SEP membrane metalloendopeptidase like 1
TCMBANKGE000988 HGF DFNB39; F-TCF; HGFB; HPTA; SF hepatocyte growth factor
TCMBANKGE001044 RPS6KB1 PS6K; S6K; S6K-beta-1; S6K1; STK14A; p70 S6KA; p70(S6K)-alpha; p70-S6K; p70-alpha ribosomal protein S6 kinase B1
TCMBANKGE001185 PPARG CIMT1; GLM1; NR1C3; PPARG1; PPARG2; PPARG5; PPARgamma peroxisome proliferator activated receptor gamma
TCMBANKGE000007 IL12B CLMF; CLMF2; IL-12B; IMD28; IMD29; NKSF; NKSF2 interleukin 12B
TCMBANKGE000884 FN1 CIG; ED-B; FINC; FN; FNZ; GFND; GFND2; LETS; MSF; SMDCF fibronectin 1
TCMBANKGE000504 IL12A CLMF; IL-12A; NFSK; NKSF1; P35 interleukin 12A
TCMBANKGE003057 STX1A HPC-1; P35-1; STX1; SYN1A syntaxin 1A
TCMBANKGE012231 UBD FAT10; GABBR1; UBD-3 ubiquitin D
TCMBANKGE001096 TLR4 ARMD10; CD284; TLR-4; TOLL toll like receptor 4
TCMBANKGE001732 ITGAL CD11A; LFA-1; LFA1A integrin subunit alpha L
TCMBANKGE000223 KEAP1 INrf2; KLHL19 kelch like ECH associated protein 1
TCMBANKGE009263 IL12RB2 - interleukin 12 receptor subunit beta 2
TCMBANKGE002355 HAMP HEPC; HFE2B; LEAP1; PLTR hepcidin antimicrobial peptide
TCMBANKGE009775 CD3D CD3-DELTA; IMD19; T3D CD3d molecule
TCMBANKGE012621 TFF3 ITF; P1B; TFI trefoil factor 3
TCMBANKGE000330 HMOX1 HMOX1D; HO-1; HSP32; bK286B10 heme oxygenase 1
TCMBANKGE009407 TYK2 IMD35; JTK1 tyrosine kinase 2
TCMBANKGE008183 ACE ACE1; CD143; DCP; DCP1 angiotensin I converting enzyme
TCMBANKGE000172 IGFBP1 AFBP; IBP1; IGF-BP25; PP12; hIGFBP-1 insulin like growth factor binding protein 1
TCMBANKGE013286 DLAT DLTA; E2; PBC; PDC-E2; PDCE2 dihydrolipoamide S-acetyltransferase
TCMBANKGE012787 ICAM3 CD50; CDW50; ICAM-R intercellular adhesion molecule 3
TCMBANKGE011776 EIF4E AUTS19; CBP; EIF4E1; EIF4EL1; EIF4F; eIF-4E eukaryotic translation initiation factor 4E
TCMBANKGE004203 TGFBR2 AAT3; FAA3; LDS1B; LDS2; LDS2B; MFS2; RIIC; TAAD2; TBR-ii; TBRII; TGFR-2; TGFbeta-RII transforming growth factor beta receptor 2
TCMBANKGE000389 MMP3 CHDS6; MMP-3; SL-1; STMY; STMY1; STR1 matrix metallopeptidase 3
TCMBANKGE000644 TNFRSF1A CD120a; FPF; TBP1; TNF-R; TNF-R-I; TNF-R55; TNFAR; TNFR1; TNFR55; TNFR60; p55; p55-R; p60 TNF receptor superfamily member 1A
TCMBANKGE006822 HHIP HIP hedgehog interacting protein
TCMBANKGE000764 TRPV1 VR1 transient receptor potential cation channel subfamily V member 1
TCMBANKGE000712 COL1A1 CAFYD; EDSARTH1; EDSC; OI1; OI2; OI3; OI4 collagen type I alpha 1 chain
TCMBANKGE002626 SPIB SPI-B Spi-B transcription factor
TCMBANKGE000315 IL4 BCGF-1; BCGF1; BSF-1; BSF1; IL-4 interleukin 4

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