Compound Summary

  Compound Information

TCMBANKIN000080

药名:	Deoxycholic Acid
别名:	SCHEMBL11962424; deoxycholic acid; Deoxycholicacid; deoxycholicacid; AKOS015965182; AC-20221
分子式:	C24H40O4
Smiles:	CC(CCC(=O)O)C1CCC2C1(C(CC3C2CCC4C3(CCC(C4)O)C)O)C
成分:	HBIN023356
OB_score:	40.723022
CAS_id:	83-44-3
SymMap_id:	SMIT10064;SMIT14992
TCMID_id:	23208;5160
TCMSP_id:	MOL008845
PubChem_id:	45358122

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   化合物对应的植物

植物ID	拉丁名	药用植物名	药名	来源	功能与主治	使用民族

TCMBANKHE006641	Calculus Bovis	牛黄			To restore consciousness by reducing fire and eliminating phlegm , to relieve convulsions, and to counteract toxicity./Ardent fever, coma, fright epilepsy, convulsion, febrile diseases clouded spirit, wind stroke with orifice block, acute infant fright wind, swelling pain in throat, mouth and tongue sores, welling abscess and flat abscess with clove sore.
TCMBANKHE004762	Selenarctos thibetanus, Ursus arctos	熊胆			To clear heat and resolve toxin, calm liver and brighten eyes, stanch bleeding and kill worms./Fright wind, epilepsy, convulsion due to liver heat and liver wind, swollen pain in red eyes due to liver heat, aversion to light, eye screen, swelling pain of welling abscess and sore, swelling pain from hemorrhoids.
TCMBANKHE007523	Folium Polygoni Tinctorii	蓼大青叶			To remove toxic heat, and to cause subsidence of eruptions by reducing heat in blood./Treatment of fever and eruptions in epidemic diseases, cough and asthma due to heat in the lung, inflammation of the throat, mnmps, erysipelas, carbuncle.
TCMBANKHE006546	Cephalotaxus fortunei	三尖杉			Anticancer./Carcinoma of stomach, carcinoma of rectum, carcinoma of lung, carcinoma of esophagus, lymphatic sarcoma, leukaemia.

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   植物对应的疾病

疾病ID	病名	疾病类型	MeSH	参考文献

TCMBANKDI000026	Obesity	disease	Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases	29859856
TCMBANKDI000031	Insulin Resistance	phenotype	Nutritional and Metabolic Diseases	29859856
TCMBANKDI002767	Fatty Liver Disease	disease	-	22531947
TCMBANKDI011257	Constipation	phenotype	Pathological Conditions, Signs and Symptoms	23041323
TCMBANKDI013656	Glucose tolerance test	phenotype	-	28490483
TCMBANKDI015496	Liver neoplasms	group	Digestive System Diseases; Neoplasms	28202625
TCMBANKDI016944	Gastrointestinal Neoplasms	group	Digestive System Diseases; Neoplasms	24520077

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   化合物对应的靶点

靶点ID	基因名	基因别名	描述

TCMBANKGE000168	NR3C1	GCCR; GCR; GCRST; GR; GRL	nuclear receptor subfamily 3 group C member 1
TCMBANKGE000199	ICAM1	BB2; CD54; P3.58	intercellular adhesion molecule 1
TCMBANKGE000201	ESR1	ER; ESR; ESRA; ESTRR; Era; NR3A1	estrogen receptor 1
TCMBANKGE000299	HMGCR	LDLCQ3	3-hydroxy-3-methylglutaryl-CoA reductase
TCMBANKGE000474	NCOA1	F-SRC-1; KAT13A; RIP160; SRC1; bHLHe42; bHLHe74	nuclear receptor coactivator 1
TCMBANKGE000476	NCOA2	GRIP1; KAT13C; NCoA-2; SRC2; TIF2; bHLHe75	nuclear receptor coactivator 2
TCMBANKGE000737	PGR	NR3C3; PR	progesterone receptor
TCMBANKGE000745	BAG3	BAG-3; BIS; CAIR-1; MFM6	BAG cochaperone 3
TCMBANKGE000781	LDLR	FH; FHC; FHCL1; LDLCQ2	low density lipoprotein receptor
TCMBANKGE000787	VCAM1	CD106; INCAM-100	vascular cell adhesion molecule 1
TCMBANKGE000810	BIRC2	API1; HIAP2; Hiap-2; MIHB; RNF48; c-IAP1; cIAP1	baculoviral IAP repeat containing 2
TCMBANKGE000844	CYP2E1	CPE1; CYP2E; P450-J; P450C2E	cytochrome P450 family 2 subfamily E member 1
TCMBANKGE000990	EGFR	ERBB; ERBB1; HER1; NISBD2; PIG61; mENA	epidermal growth factor receptor
TCMBANKGE001006	BAK1	BAK; BAK-LIKE; BCL2L7; CDN1	BCL2 antagonist/killer 1
TCMBANKGE001008	CYP3A4	CP33; CP34; CYP3A; CYP3A3; CYPIIIA3; CYPIIIA4; HLP; NF-25; P450C3; P450PCN1	cytochrome P450 family 3 subfamily A member 4
TCMBANKGE001018	MUC2	MLP; MUC-2; SMUC	mucin 2, oligomeric mucus/gel-forming
TCMBANKGE001073	PTGS2	COX-2; COX2; GRIPGHS; PGG/HS; PGHS-2; PHS-2; hCox-2	prostaglandin-endoperoxide synthase 2
TCMBANKGE001116	CYP7A1	CP7A; CYP7; CYPVII	cytochrome P450 family 7 subfamily A member 1
TCMBANKGE001173	MCL1	BCL2L3; EAT; MCL1-ES; MCL1L; MCL1S; Mcl-1; TM; bcl2-L-3; mcl1/EAT	MCL1 apoptosis regulator, BCL2 family member
TCMBANKGE001177	TP53	BCC7; BMFS5; LFS1; P53; TRP53	tumor protein p53
TCMBANKGE001795	PTPRG	HPTPG; PTPG; R-PTP-GAMMA; RPTPG	protein tyrosine phosphatase receptor type G
TCMBANKGE002388	NR3C2	MCR; MLR; MR; NR3C2VIT	nuclear receptor subfamily 3 group C member 2
TCMBANKGE004266	AR	AIS; AR8; DHTR; HUMARA; HYSP1; KD; NR3C4; SBMA; SMAX1; TFM	androgen receptor
TCMBANKGE009361	GPT	AAT1; ALT1; GPT1	glutamic--pyruvic transaminase