Compound Summary
Compound Information
药名: | dehydrocostus lactone |
别名: | dehydrocostuslactone; Azuleno[4,5-b]furan-2(3H)-one,decahydro-3,6,9-tris(methylene)-, (3aS,6aR,9aR,9bS)-; SCHEMBL699070; (3aS,6aR,9aR,9bS)-decahydro-3,6,9-tris(methylene)azuleno[4,5-b]furan-2(3H)-one; (3aR,6aS,9aS,9bR)-3,6,9-tris(methylidene)octahydroazuleno[4,5-b]furan-2,8(3H,4H)-dione; (3aS,6aR,9aR,9bS)-3,6,9-trimethylene-3a,4,5,6a,7,8,9a,9b-octahydroazuleno[5,4-d]furan-2-one; Dehydro-costus lactone (6CI,7CI); CHEMBL88985; Dehydrocostus-Lactone; 71TRF5K040; AN-45158; (3aR,6aS,9aS,9bR)-3,6,9-tris(methylene)octahydroazuleno[4,5-b]furan-2,8(3H,4H)-dione; Guaia-4(15),10(14),11(13)-trien-12-oic acid, 6alpha-hydroxy-, gamma-lactone; I07-0243; CTK5D9685; Dehydrocostus lactone; UNII-71TRF5K040; C09387; AKOS015896789; (3aS,6aR,9aR,9bS)-Decahydro-3,6,9-tris(methylene)-azuleno[4,5-b]furan-2(3H)-one; [3aS-(3aalpha,6aalpha,9aalpha,9bbeta)]-Decahydro-3,6,9-tris(methylene)-azuleno[4,5-b]furan-2(3H)-one; (3aS,6aR,9aR,9bS)-3,6,9-trimethylene-3a,4,5,6a,7,8,9a,9b-octahydroazuleno[4,5-b]furan-2-one; (3aS,6aR,9aR,9bS)-3,6,9-trimethylidene-3a,4,5,6a,7,8,9a,9b-octahydroazuleno[5,4-d]furan-2-one; CS-3636; MCULE-3657815830; SC-19761; ZB015154; (-)-Dehydrocostus lactone; Dehydrocostus lactone; Epiligulyl oxide; Dehydrocostus lactone, >=98% (HPLC); 477-43-0; (3as,6ar,9ar,9bs)-3,6,9-trimethylidenedecahydroazuleno[4,5-b]furan-2(3h)-one; ZINC898477; HY-N0591; 299D482; (3aS,6aR,9aR,9bS)-3,6,9-trimethylidene-3a,4,5,6a,7,8,9a,9b-octahydroazuleno[4,5-b]furan-2-one; CCG-208469; Azuleno(4,5-b)furan-2(3H)-one, decahydro-3,6,9-tris(methylene)-, (3aS-(3aalpha,6aalpha,9aalpha,9bbeta))-; AIDS-070708; AC1L2JE2; Azuleno(4,5-b)furan-2(3H)-one, decahydro-3,6,9-tris(methylene)-, (3aS-(3a.alpha.,6a.alpha.,9a.alpha.,9b.beta.))-; (3aS,6aR,9aR,9bS)-3,6,9-Trimethylenedecahydroazuleno[4,5-b]furan-2(9bH)-one; Dehydrocostus lactone, analytical standard; D5366; AC1Q69K0; (-)-dehydrocostuslactone; (-)-dehydrocostus lactone; FT-0082396; Azuleno[4,5-b]furan-2(3H)-one,decahydro-3,6,9-tris(methylene)-; CHEBI:244418; EBD10311; NP-009694; BDBM50370831; AIDS070708; 74299-48-2; MolPort-006-822-624 |
分子式: | C15H18O2 |
Smiles: | C=C1CCC2C(C3C1CCC3=C)OC(=O)C2=C |
成分: | HBIN023000 |
OB_score: | 58.567947 |
CAS_id: | 477-43-0 |
SymMap_id: | SMIT00368;SMIT14944 |
TCMID_id: | 23199;4890 |
TCMSP_id: | MOL001298 |
PubChem_id: | 73174 |
化合物对应的植物
| 植物ID | 拉丁名 | 药用植物名 | 药名 | 来源 | 功能与主治 | 使用民族 |
|---|
| TCMBANKHE003148 | 天山雪莲 | |||||
| TCMBANKHE004356 | Laurus nobilis | 月桂叶 | To fortify stomach and rectify qi ./Distending pain in stomach duct and abdomen, knocks and falls, scab and lichen. | |||
| TCMBANKHE004376 | Pericarpium Grati | 石榴皮 | To check diarrhea, arrest bleeding and repel worms./Chronic diarrhea, chronic dysentery, hematochezia, prolapse of rectum, flooding and spotting, leukorrhea, abdominal pain due to worm accumulation. | |||
| TCMBANKHE004522 | Rhizoma Corydalis | 延胡索 | 1. To invigorate blood and promote qi circulation; 2. To stop pain/Chest and rib-side pain, pain in stomach duct and abdomen, neuralgia, gastrointestinal spasm, amenorrhea and dysmenorrhea, postpartum stasis stagnation abdominal pain, painful swelling from knocks and falls. | |||
| TCMBANKHE004907 | 连钱草 | Treatment of acute urinary infection, urolithiasis, acute jaundice, painful swelling in sores and carbuncies, traumatic injuries. | ||||
| TCMBANKHE007615 | Rhizoma Sparganii | 三棱 | To eliminate blood stasis with strong effect, promote the flow of qi, remove the retention of undigested food, and relieve pain./Concretion conglomeration accumulation and gathering, qi-blood stagnation, pain in heart and abdomen, distending pain in rib-side, amenorrhea, postpartum blood stasis abdominal pain, knocks and falls, swelling of sores. | |||
| TCMBANKHE007831 | Vladimiria denticulata | 越西木香 | To rectify qi , relieve pain./Pain in stomach duct and rib-side, diarrhea, dysentery, indigestion. | |||
| TCMBANKHE005842 | Vladimiria souliei [Syn. Jurinea souliei] | 川木香 | To move qi and relieve pain./Distending pain in stomach duct, rumbling intestines and diarrhea, tenesmus, liver gallbladder pain. | |||
| TCMBANKHE008503 | Radix Sophorae flavescentis | 苦参 | To remove heat and damp, to kill parasites, and to cause diuresis./Arrhythmia, otitis media, acute conjunctivitis, chronic conjunctivitis, trichomoniasis, septicemia, edema, damp-heat diarrhea, intestinal wind bleeding, acute jaundice, inhibited urination, vaginal discharge, pudendal itch, scab and lichen, leprosy, itchy skin, eczema, damp toxin sore, suppurative nest sore. | |||
| TCMBANKHE007295 | Radix Aucklandiae | 木香 | To relieve pain by promoting the flow of qi, and to improve digestion by reinforcing the spleen function. /Distending pain in chest and stomach duct, diarrhea and tenesmus, non-digestion of food accumu lation, no thought of food and drink. | |||
| TCMBANKHE006664/YNS-181/XU-60/XU-236 | Fructus Arctii lappae|Arctium lappa L.|Arctium lappa | 牛蒡子;大力子|牛蒡 | 牛蒡根 | 云南药材标准：第二册|西藏昌都市洛隆县 | 祛风清热，解毒消肿，力气通便。用于咽喉肿痛，牙龈肿痛，咳嗽痰稠，腹胀便秘，消渴；黄白带下，干血痨，产后少乳，风毒面肿，大头风，疮疡肿痛|To dispel wind-heat and relieve cough, to promote eruption, to counteract toxicity, and to soothe sore throat;Treament of cough and expectroation in influenza or upper respiratory infection, measles, rubella, sore throat, mumps, erysipelas, carbuncles and sores./Wind-heat common cold, cough with profuse phlegm, measles papules, wind papules, swelling pain in throat, epidemic parotitis;1. Its extract exerts a significant and prolonged effect of lowering blood sugar in rats.2. Mildly diuretic and laxative.3. An active component, arctiin, can induce tonic convulsion, feeble respiration and eventually paralysis in frogs, mice and rabbits. erysipelas, swollen welling abscess and sore toxin. |
植物对应的疾病
| 疾病ID | 病名 | 疾病类型 | MeSH | 参考文献 |
|---|
| TCMBANKDI000013 | Bone Resorption | phenotype | Musculoskeletal Diseases | 31145860 |
化合物对应的靶点
| 靶点ID | 基因名 | 基因别名 | 描述 |
|---|
| TCMBANKGE000205 | NOS2 | HEP-NOS; INOS; NOS; NOS2A | nitric oxide synthase 2 |
| TCMBANKGE000221 | GRIA2 | GLUR2; GLURB; GluA2; GluR-K2; HBGR2; gluR-2; gluR-B | glutamate ionotropic receptor AMPA type subunit 2 |
| TCMBANKGE000241 | CASP8 | ALPS2B; CAP4; Casp-8; FLICE; MACH; MCH5 | caspase 8 |
| TCMBANKGE000715 | BID | FP497 | BH3 interacting domain death agonist |
| TCMBANKGE000766 | ACHE | ACEE; ARACHE; N-ACHE; YT | acetylcholinesterase (Cartwright blood group) |
| TCMBANKGE000813 | DPP4 | ADABP; ADCP2; CD26; DPPIV; TP103 | dipeptidyl peptidase 4 |
| TCMBANKGE000965 | CHRNA7 | CHRNA7-2; NACHRA7 | cholinergic receptor nicotinic alpha 7 subunit |
| TCMBANKGE001006 | BAK1 | BAK; BAK-LIKE; BCL2L7; CDN1 | BCL2 antagonist/killer 1 |
| TCMBANKGE001131 | CASP9 | APAF-3; APAF3; ICE-LAP6; MCH6; PPP1R56 | caspase 9 |
| TCMBANKGE001132 | BAX | BCL2L4 | BCL2 associated X, apoptosis regulator |
| TCMBANKGE001155 | CASP7 | CASP-7; CMH-1; ICE-LAP3; LICE2; MCH3 | caspase 7 |
| TCMBANKGE001156 | CASP3 | CPP32; CPP32B; SCA-1 | caspase 3 |
| TCMBANKGE001169 | BCL2L1 | BCL-XL/S; BCL2L; BCLX; Bcl-X; PPP1R52 | BCL2 like 1 |
| TCMBANKGE010767 | BMF | - | Bcl2 modifying factor |
| TCMBANKGE011079 | PRSS1 | TRP1; TRY1; TRY4; TRYP1 | serine protease 1 |
| TCMBANKGE013810 | BOK | BCL2L9; BOKL | BCL2 family apoptosis regulator BOK |
| TCMBANKGE014050 | GABRA1 | ECA4; EIEE19; EJM; EJM5 | gamma-aminobutyric acid type A receptor subunit alpha1 |
| TCMBANKGE014363 | BIK | BIP1; BP4; NBK | BCL2 interacting killer |
| TCMBANKGE014941 | DPEP1 | MBD1; MDP; RDP | dipeptidase 1 |
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