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TCMBANKDI000013

疾病ID:TCMBANKDI000013

疾病名:Bone Resorption

MeSH_Name:Musculoskeletal Diseases

HPO_Name:-

UMLS_Name:Organ or Tissue Function

DO_Name:disease of anatomical entity

疾病类型:phenotype

DisGeNET_Link:C0005974

MeSH_Link:C05

HPO_Link:-

UMLS_Link:T042

DO_Link:DOID:7

HERB_ID:-

疾病对应的植物

ID	拉丁名	药名	药用植物名	功能与主治	来源	药用部位	使用民族

TCMBANKHE003718	Flos Chrysanthemi		菊花	To dispel wind-heat, to subdue hyperactivity of the liver, and improve eyesight./Angina pectoris, hypertension, externally contracted wind-heat, wind warmth, fever and headache, dizziness, common cold, red eyes, red eyes with gall, swelling toxin of clove sore.		capitulum
TCMBANKHE005793	Flos Chrysanthemi		菊花	To dispel wind-heat, to subdue hyperactivity of the liver, and improve eyesight./Angina pectoris, hypertension, externally contracted wind-heat, wind warmth, fever and headache, dizziness, common cold, red eyes, red eyes with gall, swelling toxin of clove sore.		capitulum

疾病对应的化合物

化合物ID	化合物名	别名	分子式	分子质量	Smiles

TCMBANKIN000081	dehydrocostus lactone	dehydrocostuslactone; Azuleno[4,5-b]furan-2(3H)-one,decahydro-3,6,9-tris(methylene)-, (3aS,6aR,9aR,9bS)-; SCHEMBL699070; (3aS,6aR,9aR,9bS)-decahydro-3,6,9-tris(methylene)azuleno[4,5-b]furan-2(3H)-one; (3aR,6aS,9aS,9bR)-3,6,9-tris(methylidene)octahydroazuleno[4,5-b]furan-2,8(3H,4H)-dione; (3aS,6aR,9aR,9bS)-3,6,9-trimethylene-3a,4,5,6a,7,8,9a,9b-octahydroazuleno[5,4-d]furan-2-one; Dehydro-costus lactone (6CI,7CI); CHEMBL88985; Dehydrocostus-Lactone; 71TRF5K040; AN-45158; (3aR,6aS,9aS,9bR)-3,6,9-tris(methylene)octahydroazuleno[4,5-b]furan-2,8(3H,4H)-dione; Guaia-4(15),10(14),11(13)-trien-12-oic acid, 6alpha-hydroxy-, gamma-lactone; I07-0243; CTK5D9685; Dehydrocostus lactone; UNII-71TRF5K040; C09387; AKOS015896789; (3aS,6aR,9aR,9bS)-Decahydro-3,6,9-tris(methylene)-azuleno[4,5-b]furan-2(3H)-one; [3aS-(3aalpha,6aalpha,9aalpha,9bbeta)]-Decahydro-3,6,9-tris(methylene)-azuleno[4,5-b]furan-2(3H)-one; (3aS,6aR,9aR,9bS)-3,6,9-trimethylene-3a,4,5,6a,7,8,9a,9b-octahydroazuleno[4,5-b]furan-2-one; (3aS,6aR,9aR,9bS)-3,6,9-trimethylidene-3a,4,5,6a,7,8,9a,9b-octahydroazuleno[5,4-d]furan-2-one; CS-3636; MCULE-3657815830; SC-19761; ZB015154; (-)-Dehydrocostus lactone; Dehydrocostus lactone; Epiligulyl oxide; Dehydrocostus lactone, >=98% (HPLC); 477-43-0; (3as,6ar,9ar,9bs)-3,6,9-trimethylidenedecahydroazuleno[4,5-b]furan-2(3h)-one; ZINC898477; HY-N0591; 299D482; (3aS,6aR,9aR,9bS)-3,6,9-trimethylidene-3a,4,5,6a,7,8,9a,9b-octahydroazuleno[4,5-b]furan-2-one; CCG-208469; Azuleno(4,5-b)furan-2(3H)-one, decahydro-3,6,9-tris(methylene)-, (3aS-(3aalpha,6aalpha,9aalpha,9bbeta))-; AIDS-070708; AC1L2JE2; Azuleno(4,5-b)furan-2(3H)-one, decahydro-3,6,9-tris(methylene)-, (3aS-(3a.alpha.,6a.alpha.,9a.alpha.,9b.beta.))-; (3aS,6aR,9aR,9bS)-3,6,9-Trimethylenedecahydroazuleno[4,5-b]furan-2(9bH)-one; Dehydrocostus lactone, analytical standard; D5366; AC1Q69K0; (-)-dehydrocostuslactone; (-)-dehydrocostus lactone; FT-0082396; Azuleno[4,5-b]furan-2(3H)-one,decahydro-3,6,9-tris(methylene)-; CHEBI:244418; EBD10311; NP-009694; BDBM50370831; AIDS070708; 74299-48-2; MolPort-006-822-624	C15H18O2	230.3	C=C1CCC2C(C3C1CCC3=C)OC(=O)C2=C

疾病对应的靶点

靶点ID	基因名	基因别名	描述

TCMBANKGE001811	PTHLH	BDE2; HHM; PLP; PTHR; PTHRP	parathyroid hormone like hormone
TCMBANKGE000545	CXCL2	CINC-2a; GRO2; GROb; MGSA-b; MIP-2a; MIP2; MIP2A; SCYB2	C-X-C motif chemokine ligand 2
TCMBANKGE014985	PTH	FIH1; PTH1	parathyroid hormone
TCMBANKGE000160	COL2A1	ANFH; AOM; COL11A3; SEDC; STL1	collagen type II alpha 1 chain
TCMBANKGE000976	TNFSF11	CD254; ODF; OPGL; OPTB2; RANKL; TNLG6B; TRANCE; hRANKL2; sOdf	TNF superfamily member 11
TCMBANKGE011009	BMP7	OP-1	bone morphogenetic protein 7
TCMBANKGE000681	TNFRSF11B	OCIF; OPG; PDB5; TR1	TNF receptor superfamily member 11b
TCMBANKGE002445	GHRL	MTLRP	ghrelin and obestatin prepropeptide
TCMBANKGE001080	AHR	RP85; bHLHe76	aryl hydrocarbon receptor
TCMBANKGE000414	CYP19A1	ARO; ARO1; CPV1; CYAR; CYP19; CYPXIX; P-450AROM	cytochrome P450 family 19 subfamily A member 1