Compound Summary

  Compound Information

TCMBANKIN036795

药名:	punicalagin
别名:	punicalagin
分子式:	C48H28O30
Smiles:	c1(O[H])c(O[H])c(c2c3c(c4c(O[H])c2O[H])c(c(c(c5c([H])c(C(=O)OC([H])([H])[C@]6([H])[C@@]([H])(OC7=O)[C@@]8([H])[C@@]([H])(OC(=O)c(c([H])c(O[H])c(O[H])c9O[H])c9c(c(C(=O)O8)c([H])c%10O[H])c(O[H])c%10O[H] )[C@]([H])(O[H])O6)c(O[H])c(O[H])c5O[H])c(O[H])c%11O[H])C(=O)O4)c%11OC3=O)c7c([H])c1O[H]
成分:	HBIN041294
OB_score:	18.166029
CAS_id:	65995-63-3
SymMap_id:	SMIT00752
TCMID_id:	18190
TCMSP_id:	MOL009146
PubChem_id:	44584733

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   化合物对应的植物

植物ID	拉丁名	药用植物名	药名	来源	功能与主治	使用民族

TCMBANKHE004376	Pericarpium Grati	石榴皮			To check diarrhea, arrest bleeding and repel worms./Chronic diarrhea, chronic dysentery, hematochezia, prolapse of rectum, flooding and spotting, leukorrhea, abdominal pain due to worm accumulation.
TCMBANKHE004087/YEM-220	Fructus Quisqualis|Quisqualis indica L.	使君子	使君子	云南民族药物志：第二卷	To kill worms./Ascariasis, oxyuria disease, child gan accumulation.	阿昌族/傣族/德昂族/景颇族/傈僳族/普米族/佤族/瑶族
TCMBANKHE006576/YEM-61/XU-569	Fructus Chebulae|Terminalia chebula Retz.|Terminalia chebula var. tomentella	诃子|微毛诃子	诃子	云南民族药物志：第一卷|云南省临沧市永德县	To check diarrhea and chronic cough, and to soothe the sore throat./Chronic diarrhea and dysentery, hematochezia, prolapse of rectum, cough and asthma due to lung vacuity, incessant cough, aphonia due to throat pain.	阿昌族/傣族/德昂族/景颇族/傈僳族/藏族
TCMBANKHE004574/YEM-665	Poria|Poria cocos(Schw.)Wolf	茯苓	茯苓	云南民族药物志：第四卷	To cause diuresis, to invigorate the spleen function, and to calm the mind./Neurasthenia, disquieted heart spirit, fright palpitation and insomnia, insomnia, pelvic inflammation, edema, scant urine with edema, phlegm-rheum dizziness, reduced food intake due to spleen vacuity, sloppy stool and diarrhea, chronic diarrhea.	阿昌族/傣族/德昂族/景颇族/傈僳族/苗族/彝族/藏族
TCMBANKHE007344/YEM-665	Poria; Sclerotium Poriae Cocos; Sclerotium Poriae Cocos|Poria cocos(Schw.)Wolf	茯苓; 云苓|茯苓	茯苓	云南民族药物志：第四卷	To cause diuresis, to invigorate the spleen function, and to calm the mind.; Treatment of edema with oliguria, dizziness and palpitation caused by retained fluid, diminished function of the spleen marked by anorexia, loose stools or diarrhea, restlessness and insomnia./Neurasthenia, disquieted heart spirit, fright palpitation and insomnia, insomnia, pelvic inflammation, edema, scant urine with edema, phlegm-rheum dizziness, reduced food intake due to spleen vacuity, sloppy stool and diarrhea, chronic diarrhea.; 1. An active component pachyman promotes macrophage phagocytosis in mice, and enhances lymphocyte-blastogensis rate in vitro.2. Preventing the formation of gastric ulcer under stress in rats3. Diuretic and liver-protective.	阿昌族/傣族/德昂族/景颇族/傈僳族/苗族/彝族/藏族
TCMBANKHE005377/YEM-788	Herba Eupatorii|Eupatorium fortunei Turcz.	佩兰	水泽兰	云南民族药物志：第四卷	To resolve damp, invigorate the function of the spleen and improve appetite by its spicy fragrance, and to expel summer heat from the body surface./Nausea and vomiting, bad breath, drooling, distended head and oppression in chest, sweet-greasy in mouth, summerheat-damp exterior syndrome.	阿昌族/傣族/德昂族/哈尼族/基诺族/景颇族/拉祜族/傈僳族/苗族/彝族

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   植物对应的疾病

疾病ID	病名	疾病类型	MeSH	参考文献

TCMBANKDI000026	Obesity	disease	Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases	24393106
TCMBANKDI000029	Body Weight	phenotype	Pathological Conditions, Signs and Symptoms	24393106
TCMBANKDI000031	Insulin Resistance	phenotype	Nutritional and Metabolic Diseases	24393106
TCMBANKDI000033	Non-alcoholic Fatty Liver Disease	disease	Digestive System Diseases	24393106
TCMBANKDI000085	Inflammation	phenotype	Pathological Conditions, Signs and Symptoms	28690198
TCMBANKDI032496	Hyperlipidemia	disease	Nutritional and Metabolic Diseases	30878647

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   化合物对应的靶点

靶点ID	基因名	基因别名	描述

TCMBANKGE000037	CSF1	CSF-1; MCSF	colony stimulating factor 1
TCMBANKGE000038	SLC11A1	LSH; NRAMP; NRAMP1	solute carrier family 11 member 1
TCMBANKGE000039	TMEM171	PRP2	transmembrane protein 171
TCMBANKGE000040	IRF2	IRF-2	interferon regulatory factor 2
TCMBANKGE000041	IRF1	IRF-1; MAR	interferon regulatory factor 1
TCMBANKGE000042	GPR35	-	G protein-coupled receptor 35
TCMBANKGE000043	BHLHE40	BHLHB2; Clast5; DEC1; HLHB2; SHARP-2; SHARP2; STRA13; Stra14	basic helix-loop-helix family member e40
TCMBANKGE000047	AKT1	AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA	AKT serine/threonine kinase 1
TCMBANKGE000051	IL1B	IL-1; IL1-BETA; IL1F2; IL1beta	interleukin 1 beta
TCMBANKGE000052	TNF	DIF; TNF-alpha; TNFA; TNFSF2; TNLG1F	tumor necrosis factor
TCMBANKGE000053	NFKB1	CVID12; EBP-1; KBF1; NF-kB; NF-kB1; NF-kappa-B1; NF-kappaB; NF-kappabeta; NFKB-p105; NFKB-p50; NFkappaB	nuclear factor kappa B subunit 1
TCMBANKGE000075	IL1RN	DIRA; ICIL-1RA; IL-1RN; IL-1ra; IL-1ra3; IL1F3; IL1RA; IRAP; MVCD4	interleukin 1 receptor antagonist
TCMBANKGE000226	UCP2	BMIQ4; SLC25A8; UCPH	uncoupling protein 2
TCMBANKGE000238	IL10	CSIF; GVHDS; IL-10; IL10A; TGIF	interleukin 10
TCMBANKGE000246	FOXO1	FKH1; FKHR; FOXO1A	forkhead box O1
TCMBANKGE000315	IL4	BCGF-1; BCGF1; BSF-1; BSF1; IL-4	interleukin 4
TCMBANKGE000318	HMGB1	HMG-1; HMG1; HMG3; SBP-1	high mobility group box 1
TCMBANKGE000330	HMOX1	HMOX1D; HO-1; HSP32; bK286B10	heme oxygenase 1
TCMBANKGE001042	PTPN1	PTP1B	protein tyrosine phosphatase non-receptor type 1
TCMBANKGE001063	CEBPB	C/EBP-beta; IL6DBP; NF-IL6; TCF5	CCAAT enhancer binding protein beta
TCMBANKGE001096	TLR4	ARMD10; CD284; TLR-4; TOLL	toll like receptor 4
TCMBANKGE001114	IL6	BSF-2; BSF2; CDF; HGF; HSF; IFN-beta-2; IFNB2; IL-6	interleukin 6
TCMBANKGE001126	NFE2L2	HEBP1; IMDDHH; NRF2; Nrf-2	nuclear factor, erythroid 2 like 2
TCMBANKGE001148	VEGFA	MVCD1; VEGF; VPF	vascular endothelial growth factor A
TCMBANKGE001149	PPARGC1A	LEM6; PGC-1(alpha); PGC-1alpha; PGC-1v; PGC1; PGC1A; PPARGC1	PPARG coactivator 1 alpha
TCMBANKGE001159	STAT1	CANDF7; IMD31A; IMD31B; IMD31C; ISGF-3; STAT91	signal transducer and activator of transcription 1
TCMBANKGE001178	STAT3	ADMIO; ADMIO1; APRF; HIES	signal transducer and activator of transcription 3
TCMBANKGE001197	FOS	AP-1; C-FOS; p55	Fos proto-oncogene, AP-1 transcription factor subunit
TCMBANKGE001202	MAPK14	CSBP; CSBP1; CSBP2; CSPB1; EXIP; Mxi2; PRKM14; PRKM15; RK; SAPK2A; p38; p38ALPHA	mitogen-activated protein kinase 14