Compound Summary


  Compound Information

药名:

triptonide

别名:

Triptolide, 14-deoxy-14-oxo-; AC-20331; 38647-11-9; KBio1_001608; Spectrum_001724; AKOS025401513; KBioSS_002204; BC216334; NSC165677; NCI60_001273; DivK1c_006664; Triptonide; KBio2_004772; SPBio_000614; Spectrum2_000477; KBio2_007340; Spectrum5_001806; ZINC100038923; SpecPlus_000568; KBio2_002204

分子式:

C20H22O6

Smiles:

C12=C(C([H])([H])C([H])([H])[C@]3(C([H])([H])[H])[C@@]1([H])C([H])([H])[C@@]([H])(O4)[C@]45[C@]36[C@]([H])(O6)[C@]7([H])[C@@](C([H])(C([H])([H])[H])C([H])([H])[H])(O7)C5=O)C(=O)OC2([H])[H]

成分:

HBIN047177

SymMap_id:

SMIT01653;SMIT05314

TCMID_id:

21997

TCMSP_id:

MOL003192;MOL003244

PubChem_id:

65411


   化合物对应的植物
植物ID 拉丁名 药用植物名 药名 来源 功能与主治 使用民族
TCMBANKHE003373 Exocarpium Citri grandis 化橘红 To dispel cold, eliminate damp and phlegm, and arrest emesis or nausea./Treatment of cough, itching of the throat and profuse expectoration in colds, nausea, vomiting and epigastric distension caused by improper diet or excessive drinking.
TCMBANKHE003734 radix tripterygii wilfordii 雷公藤 To expel wind-dampness, relieve swelling, alleviate pain and dredge the meridian passage./Rheumatoid arthritis, rheumatic arthritis, glomerulonephritis, nephropathy syndrome, erythematous lupus, dryness in eyes and mouth, Behcet’s syndrome, psoriasis, eczema, leprosy, scab sore, intractable lichen.
TCMBANKHE005716/YEM-243 Semen Canbis;Fructus Canbis;Fructus cannabis|Cannabis sativa L. 火麻仁;麻子仁|大麻 大麻 云南民族药物志:第二卷 To cause Taxation.;Purging by moisterizing/Blood and liquid depletion, intestinal dry and constipation. 阿昌族/傣族/德昂族/哈尼族/景颇族/傈僳族/苗族/彝族/藏族
TCMBANKHE005898/YNS-113/YEM-98/XU-75 Tripterygium hypoglaucum|Tripterygium hypoglaucu (Lévl.) Hutch.|Tripterygium hypoglaucum (Lévl. )Lévl.ex ex Hutch. 昆明山海棠 火把花根|昆明山海棠 云南药材标准:第二册|云南民族药物志:第一卷|云南省保山市隆阳区瓦房乡 祛风除湿,舒经通络,消肿止痛。用于风寒湿痹,关节肿痛,跌倒损伤,红斑狼疮,皮痹瘙痒骨痨骨疽,睾丸结核|To dispel wind and eliminate damp, quicken blood and stanch bleeding, soothe sinews and joint bones, resolve toxin and kill worms./Rheumatic arthritis, wind-damp impediment pain, hemiplegia, mounting qi , dysmenorrhea, profuse menstruation, postpartum abdominal pain, incessant bleeding, acute infectious hepatitis, chronic nephritis, erythematous lupus, fracture, medullitis, bone tuberculosis, epididymis tubercle, sore toxin, psoriasis, neurodermatitis. 哈尼族/拉祜族/傈僳族/彝族

   植物对应的疾病
疾病ID 病名 疾病类型 MeSH 参考文献
TCMBANKDI000006 Nasopharyngeal Neoplasms group Neoplasms; Stomatognathic Diseases; Otorhinolaryngologic Diseases 30503558
TCMBANKDI000082 Nasopharyngeal carcinoma disease Neoplasms; Stomatognathic Diseases; Otorhinolaryngologic Diseases 30503558

   化合物对应的靶点
靶点ID 基因名 基因别名 描述
TCMBANKGE000182 B4galnt2 AI593864; Dlb-1; Dlb1; Galg2; Galgt2; Ggm3; Igf2bp1 beta-1,4-N-acetyl-galactosaminyl transferase 2
TCMBANKGE000183 D7Zem2 Igf2; MAR2 DNA segment, Chr 7, Zemel 2
TCMBANKGE000184 IGF2BP1 CRD-BP; CRDBP; IMP-1; IMP1; VICKZ1; ZBP1 insulin like growth factor 2 mRNA binding protein 1
TCMBANKGE000185 D7Zem3 Igf2; MAR3 DNA segment, Chr 7, Zemel 3
TCMBANKGE000186 IGF2 C11orf43; GRDF; IGF-II; PP9974 insulin like growth factor 2
TCMBANKGE000187 D7Zem1 Igf2; MAR1 DNA segment, Chr 7, Zemel 1
TCMBANKGE000551 NOL3 ARC; FCM; MYOCL1; MYP; NOP; NOP30 nucleolar protein 3
TCMBANKGE000898 MYC MRTL; MYCC; bHLHe39; c-Myc MYC proto-oncogene, bHLH transcription factor
TCMBANKGE000909 GLI1 GLI; PAPA8; PPD1 GLI family zinc finger 1