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疾病ID:TCMBANKDI000006
疾病名:Nasopharyngeal Neoplasms
MeSH_Name:Neoplasms; Stomatognathic Diseases; Otorhinolaryngologic Diseases
HPO_Name:Neoplasm; Abnormality of head or neck; Abnormality of the respiratory system
UMLS_Name:Neoplastic Process
DO_Name:disease of anatomical entity; disease of cellular proliferation
疾病类型:group
DisGeNET_Link:C0027439
MeSH_Link:C04; C07; C09
HPO_Link:HP:0002664; HP:0000152; HP:0002086
UMLS_Link:T191
DO_Link:DOID:7; DOID:14566
HERB_ID:HBDIS002054
疾病对应的植物
| ID | 拉丁名 | 药名 | 药用植物名 | 功能与主治 | 来源 | 药用部位 | 使用民族 |
|---|
| TCMBANKHE003734 | radix tripterygii wilfordii | 雷公藤 | To expel wind-dampness, relieve swelling, alleviate pain and dredge the meridian passage./Rheumatoid arthritis, rheumatic arthritis, glomerulonephritis, nephropathy syndrome, erythematous lupus, dryness in eyes and mouth, Behcet’s syndrome, psoriasis, eczema, leprosy, scab sore, intractable lichen. | root, leaf and flower |
疾病对应的化合物
| 化合物ID | 化合物名 | 别名 | 分子式 | 分子质量 | Smiles |
|---|
| TCMBANKIN036848 | triptolide | PG 490; CT0223; Bio2_000315; AKOS015895128; KBio2_005451; BSPBio_001595; NCGC00163411-02; Triptolide; BCPP000033; Trisoxireno[4b,5:6,7:8a,9]phenanthro[1,2-c]furan-(3H)-one, 3b,4,4a,6,6a,7a,7b,8b,9,10-decahydro-6-hydroxy-8b-methyl-6a-(1-methylethyl)-, [3bR-(3b.alpha.,4a.alpha.,5aS*,6.beta.,6a.beta.,7a.beta.,7b.alpha.,8aS*,8b.beta.)]-; KBio3_000629; N1733; CHEBI:94966; SCHEMBL10028421; Trisoxireno(4b,5:6,7:8a,9)phenanthro(1,2-c)furan-1(3H)-one, 3b,4,4a,6,6a,7a,7b,8b,9,10-decahydro-6-hydroxy-8b-methyl-6a-(1-methylethyl)-, (3bS,4aS,5aS,6R,6aR,7aS,7bS,8aS,8bS)-; AC-6084; IDI1_034065; NCGC00163411-01; NSC163062; KBio2_002883; NSC 163062; Bio2_000795; Triptolid; HY-32735; BRD-A13122391-001-01-9; SMR000466307; MLS000759410; Triptolide (9CI); C09204; Triptolide, <i>Tripterygium wilfordii; PG-490; ST51052768; KBio2_000315; Trisoxireno[4b,5:6,7:8a,9]phenanthro[1,2-c]furan-1(3H)-one, 3b,4,4a,6,6a,7a,7b,8b,9,10-decahydro-6-hydroxy-8b-methyl-6a-(1-methylethyl)-, [3bR-(3b.alpha.,4a.alpha.,5aS*,6.beta.,6a.beta.,7a.beta.,7b.alpha.,8aS*,8b.beta.)]-; CS-0286; KBio3_000630; Triptolide, from Tripterygium wilfordii, >=98% (HPLC), solid; 38748-32-2; PG490; SMP1_000110; KBioGR_000315; TPL; NCI60_001223; KBioSS_000315 | C20H24O6 | 360.4 | CC(C)C12C(O1)C3C4(O3)C5(CCC6=C(C5CC7C4(C2O)O7)COC6=O)C |
疾病对应的靶点
| 靶点ID | 基因名 | 基因别名 | 描述 |
|---|
| TCMBANKGE007237 | BCL2L12 | - | BCL2 like 12 |
| TCMBANKGE003804 | FGFR2 | BBDS; BEK; BFR-1; CD332; CEK3; CFD1; ECT1; JWS; K-SAM; KGFR; TK14; TK25 | fibroblast growth factor receptor 2 |
| TCMBANKGE009472 | AKR1B10 | AKR1B11; AKR1B12; ALDRLn; ARL-1; ARL1; HIS; HSI | aldo-keto reductase family 1 member B10 |
| TCMBANKGE000567 | CDKN2A | ARF; CDK4I; CDKN2; CMM2; INK4; INK4A; MLM; MTS-1; MTS1; P14; P14ARF; P16; P16-INK4A; P16INK4; P16INK4A; P19; P19ARF; TP16 | cyclin dependent kinase inhibitor 2A |
| TCMBANKGE000896 | SFRP1 | FRP; FRP-1; FRP1; FrzA; SARP2 | secreted frizzled related protein 1 |
| TCMBANKGE002546 | PFN1 | ALS18 | profilin 1 |
| TCMBANKGE009458 | MST1R | CD136; CDw136; NPCA3; PTK8; RON; SEA | macrophage stimulating 1 receptor |
| TCMBANKGE000009 | GJA1 | AVSD3; CMDR; CX43; EKVP; EKVP3; GJAL; HLHS1; HSS; ODDD; PPKCA | gap junction protein alpha 1 |
| TCMBANKGE000466 | CYP2A6 | CPA6; CYP2A; CYP2A3; CYPIIA6; P450C2A; P450PB | cytochrome P450 family 2 subfamily A member 6 |
| TCMBANKGE013860 | EDNRA | ET-A; ETA; ETA-R; ETAR; ETRA; MFDA; hET-AR | endothelin receptor type A |
| TCMBANKGE000844 | CYP2E1 | CPE1; CYP2E; P450-J; P450C2E | cytochrome P450 family 2 subfamily E member 1 |
| TCMBANKGE000986 | ERBB2 | CD340; HER-2; HER-2/neu; HER2; MLN 19; NEU; NGL; TKR1 | erb-b2 receptor tyrosine kinase 2 |
| TCMBANKGE000068 | VEGFC | Flt4-L; LMPH1D; LMPHM4; VRP | vascular endothelial growth factor C |
| TCMBANKGE001037 | MMP2 | CLG4; CLG4A; MMP-2; MMP-II; MONA; TBE-1 | matrix metallopeptidase 2 |
| TCMBANKGE001532 | ERCC1 | COFS4; RAD10; UV20 | ERCC excision repair 1, endonuclease non-catalytic subunit |
| TCMBANKGE008095 | CEP128 | C14orf145; C14orf61; LEDP/132 | centrosomal protein 128 |
| TCMBANKGE004826 | FLT4 | CHTD7; FLT-4; FLT41; LMPH1A; LMPHM1; PCL; VEGFR-3; VEGFR3 | fms related receptor tyrosine kinase 4 |
| TCMBANKGE001178 | STAT3 | ADMIO; ADMIO1; APRF; HIES | signal transducer and activator of transcription 3 |
| TCMBANKGE012841 | HLA-A | HLAA | major histocompatibility complex, class I, A |
| TCMBANKGE007385 | NRAS | ALPS4; CMNS; N-ras; NCMS; NRAS1; NS6 | NRAS proto-oncogene, GTPase |
| TCMBANKGE000822 | ANXA5 | ANX5; ENX2; HEL-S-7; PP4; RPRGL3 | annexin A5 |
| TCMBANKGE004806 | TNFRSF19 | TAJ; TAJ-alpha; TRADE; TROY | TNF receptor superfamily member 19 |
| TCMBANKGE009874 | CDKN2B | CDK4I; INK4B; MTS2; P15; TP15; p15INK4b | cyclin dependent kinase inhibitor 2B |
| TCMBANKGE000988 | HGF | DFNB39; F-TCF; HGFB; HPTA; SF | hepatocyte growth factor |
| TCMBANKGE000240 | IL17A | CTLA-8; CTLA8; IL-17; IL-17A; IL17 | interleukin 17A |
| TCMBANKGE012048 | HLA-B | AS; B-4901; HLAB | major histocompatibility complex, class I, B |
| TCMBANKGE012286 | WIF1 | WIF-1 | WNT inhibitory factor 1 |
| TCMBANKGE005995 | PALB2 | FANCN; PNCA3 | partner and localizer of BRCA2 |
| TCMBANKGE011220 | CIITA | C2TA; CIITAIV; MHC2TA; NLRA | class II major histocompatibility complex transactivator |
| TCMBANKGE007284 | MECOM | AML1-EVI-1; EVI1; KMT8E; MDS1; MDS1-EVI1; PRDM3; RUSAT2 | MDS1 and EVI1 complex locus |
| TCMBANKGE000639 | HRAS | C-BAS/HAS; C-H-RAS; C-HA-RAS1; CTLO; H-RASIDX; HAMSV; HRAS1; RASH1; p21ras | HRas proto-oncogene, GTPase |
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