Compound Summary


  Compound Information

药名:

Hispaglabridin B

别名:

3386OSM882; CHEMBL464582; 2H-1-Benzopyran-5-ol, 6-(3,4-dihydro-8,8-dimethyl-2H,8H-benzo(1,2-b:3,4-b')dipyran-3-yl)-2,2-dimethyl-, (R)-; 2H-1-Benzopyran-5-ol, 6-((3R)-3,4-dihydro-8,8-dimethyl-2H,8H-benzo(1,2-b:3,4-b')dipyran-3-yl)-2,2-dimethyl-; 2H,8H-Benzo(1,2-b:3,4-b')dipyran, 2H-1-benzopyran-5-ol deriv.; hispaglabridin b; UNII-3386OSM882; 68978-02-9

分子式:

C25H26O4

Smiles:

CC1(C=CC2=C(O1)C=CC(=C2O)C3CC4=C(C5=C(C=C4)OC(C=C5)(C)C)OC3)C

成分:

HBIN029423

OB_score:

22.938235

SymMap_id:

SMIT06748;SMIT15763

TCMID_id:

9557

TCMSP_id:

MOL004906

PubChem_id:

15228661


   化合物对应的植物
植物ID 拉丁名 药用植物名 药名 来源 功能与主治 使用民族
TCMBANKHE003728 Radix Glycyrrhizae 甘草 To reinforce the function of the spleen and replenish qi, to remove heat and counteract toxicity, to dispel phlegm and relieve cough, to alleviate spasmodic pain, and to moderate drug actions./1. Its decoction can inhibit intestinal smooth muscles of rabbins in vitro, but glycyrrhizin and glycyrrhetinic acid have no this effect.2. Possessing an adrenocorticomimetic effect.3. Its extract and glycyrrhizin exerts a detoxifying effect.4. Antitussive and antiasthmatic. 5. Glycyrrhizin has anti-inflammatory effect similar to hydrocortisone.
TCMBANKHE004954 Glycyrrhiza glabra var. typica 欧亚甘草
TCMBANKHE007721 Exocarpium Benincasae 冬瓜皮 1. To promote diuresis to relieve edema. 2. To clear summer-heat./Edema, inhibited urination [=dysuria], diarrhea, swelling of sores.
TCMBANKHE006338 Glycyrrhiza glabra 光果甘草 See Glycyrrhiza uralensis ./See Glycyrrhiza uralensis .

   植物对应的疾病
疾病ID 病名 疾病类型 MeSH 参考文献
TCMBANKDI026758 Muscular Atrophy phenotype Pathological Conditions, Signs and Symptoms; Nervous System Diseases 30270561

   化合物对应的靶点
靶点ID 基因名 基因别名 描述
TCMBANKGE000246 FOXO1 FKH1; FKHR; FOXO1A forkhead box O1
TCMBANKGE000629 FBXO32 Fbx32; MAFbx F-box protein 32
TCMBANKGE000630 TRIM63 IRF; MURF1; MURF2; RNF28; SMRZ tripartite motif containing 63