Compound Summary

  Compound Information

TCMBANKIN036908

药名:	oleuropein
别名:	32619-42-4; (4S,5Z,6R)-4-[2-[2-(3,4-dihydroxyphenyl)ethoxy]-2-oxoethyl]-5-ethylidene-6-[[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)-2-oxanyl]oxy]-4H-pyran-3-carboxylic acid methyl ester; methyl (4S,5Z,6R)-4-[2-[2-(3,4-dihydroxyphenyl)ethoxy]-2-oxo-ethyl]-5-ethylidene-6-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]oxy-4H-pyran-3-carboxylate; CO0035; ZINC70647110; methyl (4S,5Z,6R)-4-[2-[2-[3,4-bis(oxidanyl)phenyl]ethoxy]-2-oxidanylidene-ethyl]-5-ethylidene-6-[(2S,3R,4S,5S,6R)-6-(hydroxymethyl)-3,4,5-tris(oxidanyl)oxan-2-yl]oxy-4H-pyran-3-carboxylate; A821341; Oleuropein
分子式:	C25H32O13
Smiles:	CC=C1C(C(=COC1OC2C(C(C(C(O2)CO)O)O)O)C(=O)OC)CC(=O)OCCC3=CC(=C(C=C3)O)O
成分:	HBIN038054
OB_score:	4.953236
CAS_id:	32619-42-4
SymMap_id:	SMIT00226
TCMID_id:	16070
TCMSP_id:	MOL005176
PubChem_id:	134688908

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   化合物对应的植物

植物ID	拉丁名	药用植物名	药名	来源	功能与主治	使用民族

TCMBANKHE002552		零陵香
TCMBANKHE003764	Ligustrum japonicum	日本女贞			To clear liver fire, resolve heat toxin./Dizziness and dim vision, acute conjunctivitis, oral gan , tooth decay, innominate toxin swelling, burns and scalds.
TCMBANKHE004113	Fraxinus ornus	花白蜡树
TCMBANKHE004497	Semen Raphani	莱菔子			To promote digestion and relieve abdominal distension, and to relieve cough and resolve phlegm./Food stagnation, distending pain in stomach duct, constipation, accumulation and diarrhea, phlegm congestion cough asthma.
TCMBANKHE004843	Cervus nippon , Cervus elaphus	鹿茸			To supplement kidney and invigorate yang , boost essence and blood, strengthen sinews and bones, regulate thoroughfare and controlling vessels, draw sore toxin./Impotence and emission, infertility due to uterus cold, marked emaciation, thrombocytopenia, septicemia, fatigued spirit, aversion of cold, dizziness, tinnitus and deafness, aching pain in lumbus and back, limp wilting sinew and bone, flooding and spotting with vaginal discharge, enduring yin flat abscess.
TCMBANKHE007311	Ilex pubescens	毛冬青			To clear heat and resolve toxin, quicken blood and free network vessels./Angina pectoris, acute myocardial infarction, cerebral thrombosis, thrombophlebitis, thromboangiitis obliterans (Buerger’s disease), central retinitis, central angiospastic retinitis, wind-heat common cold, lung heat cough asthma, sore pharynx, nipple moth, gum swelling and pain, chest impediment and heart pain, wind stroke with hemiplegia, erysipelas, burns and scalds, welling abscess and flat abscess.
TCMBANKHE008470	Fraxinus chinensis	白蜡树			See Fraxinus rhynchophylla./See Fraxinus rhynchophylla .
TCMBANKHE006065	Fraxinus japonica	日本白蜡树
TCMBANKHE007622	Olea europaea	油橄榄			To moisten intestines and free stool, resolve toxin and close sores, lower blood pressure, lower blood-fat./Intestinal dry and constipation, burns and scalds, coronary heart disease.
TCMBANKHE004023/YEM-391/XU-797	Fructus Ligustri lucidi|Ligustrum lucidum Ait.|Ligustrum lucidum	女贞子|女贞	女贞子	云南民族药物志：第二卷|云南省文山州麻栗坡县	To replenish the liver and kidney, improve eyesight and promote the growth of black hair.;Treament of vertigo, tinnitus, weakness in the loins and knees, premature whitening of hair and impaired eyesight due to deficiency of yin of the liver and kidney./Septicemia, chronic bronchitis, acute dysentery, dizziness and tinnitus, premature graying in beard and hair, dim vision.;1. Its component oleanolic acid can prevent and relieve cyclophosphamide-induced leukocytopenia in mice.2. Enhancing the anoxia tolerance of mice under atmospheric pressure.3. Increasing coronary flow in rabbits in vitro.4. Relaxing adrenaline-induced vasocontricyion in rabbits in vitro.5. Lowering the level of blood lipid.	阿昌族/德昂族/基诺族/景颇族/傈僳族/水族

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   植物对应的疾病

疾病ID	病名	疾病类型	MeSH	参考文献

TCMBANKDI000006	Nasopharyngeal Neoplasms	group	Neoplasms; Stomatognathic Diseases; Otorhinolaryngologic Diseases	28057028
TCMBANKDI000017	Liver Cirrhosis	disease	Pathological Conditions, Signs and Symptoms; Digestive System Diseases	21145829
TCMBANKDI000033	Non-alcoholic Fatty Liver Disease	disease	Digestive System Diseases	21145829
TCMBANKDI000082	Nasopharyngeal carcinoma	disease	Neoplasms; Stomatognathic Diseases; Otorhinolaryngologic Diseases	28057028
TCMBANKDI008514	Carcinoma	group	Neoplasms	28057028
TCMBANKDI012877	Cardiomyopathies	group	Cardiovascular Diseases	24486195
TCMBANKDI021229	Fatty Liver	disease	Digestive System Diseases	21145829

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   化合物对应的靶点

靶点ID	基因名	基因别名	描述

TCMBANKGE000047	AKT1	AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA	AKT serine/threonine kinase 1
TCMBANKGE000205	NOS2	HEP-NOS; INOS; NOS; NOS2A	nitric oxide synthase 2
TCMBANKGE000330	HMOX1	HMOX1D; HO-1; HSP32; bK286B10	heme oxygenase 1
TCMBANKGE001032	WNT10B	SHFM6; STHAG8; WNT-12	Wnt family member 10B
TCMBANKGE001033	FGFR1	BFGFR; CD331; CEK; ECCL; FGFBR; FGFR-1; FLG; FLT-2; FLT2; HBGFR; HH2; HRTFDS; KAL2; N-SAM; OGD; bFGF-R-1	fibroblast growth factor receptor 1
TCMBANKGE001034	TLR2	CD282; TIL4	toll like receptor 2
TCMBANKGE001035	PDRG1	C20orf126; PDRG	p53 and DNA damage regulated 1
TCMBANKGE001096	TLR4	ARMD10; CD284; TLR-4; TOLL	toll like receptor 4
TCMBANKGE001097	HIF1A	HIF-1-alpha; HIF-1A; HIF-1alpha; HIF1; HIF1-ALPHA; MOP1; PASD8; bHLHe78	hypoxia inducible factor 1 subunit alpha
TCMBANKGE001112	PRKAB1	AMPK; HAMPKb	protein kinase AMP-activated non-catalytic subunit beta 1
TCMBANKGE001126	NFE2L2	HEBP1; IMDDHH; NRF2; Nrf-2	nuclear factor, erythroid 2 like 2
TCMBANKGE001127	PRKAA1	AMPK; AMPKa1	protein kinase AMP-activated catalytic subunit alpha 1
TCMBANKGE001128	PRKAA2	AMPK; AMPK2; AMPKa2; PRKAA	protein kinase AMP-activated catalytic subunit alpha 2