Compound Summary

  Compound Information

TCMBANKIN036916

药名:	Artemisinin
别名:	BSPBio_002998; KBio2_001831; BRN 4194670; Prestwick1_000498; LMPR01030025; Spectrum_001351; Artemisia annua L., extract; (3R,5aS,6R,8aS,9R,12S,12aR)-Octahydro-3,6,9-trimethyl-3,12-epoxy-12H-pyrano(4,3-j)-1,2-benzodioxepin-10(3H)-one; KBio2_004399; KBioSS_001831; KBio2_006967; Spectrum2_001512; Huanghuahaosu; Qinghaosu; Qing Hao Su; SPBio_001583; Artemisinine [French]; Artemisininum [Latin]; Arteannuin; (+)-Artemisinin; Artemisinina [Spanish]; artemisinin ; BPBio1_000435; Cotexin; KBio1_000656; Prestwick3_000498; KBioGR_000982; Qinghosu; Qinghaosu [Chinese]; Artesin; Quing Hau Sau; Prestwick2_000498; Spectrum5_001098; IDI1_000656; C09538; DivK1c_000656; Artemisinin [INN]; Artemisine; Qing Hau SU; 3,12-Epoxy-12H-pyranol(4,3-j)-1,2-benzodioxepin-10(3H)-one, octahydro-3,6,9-trimethyl-, (3-alpha,5a-beta,6-beta,8a-beta,9-alpha,12-beta,12aR*)-(+)-; BSPBio_000395; Octahydro-3,6,9-trimethyl-3,12-epoxy-12H-pyrano(4,3-j)-1,2-benzodioxepin-10(3H)-one; NSC 369397; Spectrum3_001549; KBio3_002498; 63968-64-9; NINDS_000656; SPBio_002316; Spectrum4_000721; D02481; Artemisinin; Artemisinine; Prestwick0_000498; Qing Hau Sau [Chinese]
分子式:	C15H22O5
Smiles:	C1([H])([H])[C@]2([H])[C@]3([C@@]([H])(O[C@@](C([H])([H])[H])(OO3)C([H])([H])C4([H])[H])OC(=O)[C@]2([H])C([H])([H])[H])[C@]4([H])[C@]([H])(C([H])([H])[H])C1([H])[H]
成分:	HBIN016960
OB_score:	49.87926
CAS_id:	63968-64-9
SymMap_id:	SMIT08863
TCMID_id:	23257
TCMSP_id:	MOL007424
PubChem_id:	137704955
DrugBank_id:	DB13132

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   化合物对应的植物

植物ID	拉丁名	药用植物名	药名	来源	功能与主治	使用民族

TCMBANKHE005093	Massa Medicata Fermentata	六神曲			Treatment of retention of food manifested as epigastric and abdominal distension and fullness, no appetite, gurgling sound and diarrhea. Medicated leaven (Shenqu) is used with Hawthorn fruit (Shanzha) and Germinated barley (Maiya)./Treatment of retention of food manifested as epigastric and abdominal distension and fullness, no appetite, gurgling sound and diarrhea. Medicated leaven (Shenqu) is used with Hawthorn fruit (Shanzha) and Germinated barley (Maiya).
TCMBANKHE008476/YEM-68	Artemisia annua|Artemisia annua L.	黄花蒿	黄花蒿	云南民族药物志：第一卷	To clear heat, resolve summerheat, eliminate steam, interrupt malaria./Summerheat-heat, summerheat-damp, damp warmth, yin vacuity fever, malaria, jaundice.	阿昌族/白族/傣族/德昂族/独龙族/景颇族/傈僳族/纳西族/怒族/瑶族/彝族/藏族/壮族
TCMBANKHE006570/YEM-68	Herba Artemisiae Annuae|Artemisia annua L.	青蒿|黄花蒿	黄花蒿	云南民族药物志：第一卷	To remove summer-heat, to relieve consumptive fever,and to stop malarial attacks./See Artemisia annua.	阿昌族/白族/傣族/德昂族/独龙族/景颇族/傈僳族/纳西族/怒族/瑶族/彝族/藏族/壮族

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   植物对应的疾病

疾病ID	病名	疾病类型	MeSH	参考文献

TCMBANKDI004122	Parasitemia	disease	Pathological Conditions, Signs and Symptoms; Infections	21709259
TCMBANKDI005503	Malaria, Falciparum	disease	Infections	25910630
TCMBANKDI012119	Nerve Degeneration	phenotype	Pathological Conditions, Signs and Symptoms	27242266
TCMBANKDI014919	Malaria, Vivax	disease	Infections	30337251
TCMBANKDI015757	Malaria	disease	Infections	31806760
TCMBANKDI023904	Macular degeneration	disease	Pathological Conditions, Signs and Symptoms; Eye Diseases; Nervous System Diseases	27372058
TCMBANKDI023986	Coinfection	phenotype	Infections	30587297

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   化合物对应的靶点

靶点ID	基因名	基因别名	描述

TCMBANKGE000068	VEGFC	Flt4-L; LMPH1D; LMPHM4; VRP	vascular endothelial growth factor C
TCMBANKGE000205	NOS2	HEP-NOS; INOS; NOS; NOS2A	nitric oxide synthase 2
TCMBANKGE000264	ABCB1	ABC20; CD243; CLCS; GP170; MDR1; P-GP; PGY1	ATP binding cassette subfamily B member 1
TCMBANKGE000453	NR1I3	CAR; CAR1; MB67	nuclear receptor subfamily 1 group I member 3
TCMBANKGE000458	CYP2B6	CPB6; CYP2B; CYP2B7; CYP2B7P; CYPIIB6; EFVM; IIB1; P450	cytochrome P450 family 2 subfamily B member 6
TCMBANKGE001007	NR1I2	BXR; ONR1; PAR; PAR1; PAR2; PARq; PRR; PXR; SAR; SXR	nuclear receptor subfamily 1 group I member 2
TCMBANKGE001008	CYP3A4	CP33; CP34; CYP3A; CYP3A3; CYPIIIA3; CYPIIIA4; HLP; NF-25; P450C3; P450PCN1	cytochrome P450 family 3 subfamily A member 4
TCMBANKGE001076	SOD2	GClnc1; IPO-B; IPOB; MNSOD; MVCD6; Mn-SOD	superoxide dismutase 2
TCMBANKGE001097	HIF1A	HIF-1-alpha; HIF-1A; HIF-1alpha; HIF1; HIF1-ALPHA; MOP1; PASD8; bHLHe78	hypoxia inducible factor 1 subunit alpha
TCMBANKGE001148	VEGFA	MVCD1; VEGF; VPF	vascular endothelial growth factor A
TCMBANKGE001170	CDK4	CMM3; PSK-J3	cyclin dependent kinase 4
TCMBANKGE001184	RELA	CMCU; NFKB3; p65	RELA proto-oncogene, NF-kB subunit
TCMBANKGE003984	TDP1	-	tyrosyl-DNA phosphodiesterase 1
TCMBANKGE007368	GSTP1	DFN7; FAEES3; GST3; GSTP; HEL-S-22; PI	glutathione S-transferase pi 1
TCMBANKGE013273	PRDX4	AOE37-2; AOE372; HEL-S-97n; PRX-4	peroxiredoxin 4
TCMBANKGE014249	GSTA1	GST-epsilon; GST2; GSTA1-1; GTH1	glutathione S-transferase alpha 1