Compound Summary

  Compound Information

TCMBANKIN037830

化合物待补充

药名:	Picropodophyllin
别名:	(10R,11S,16R)-16-hydroxy-10-(3,4,5-trimethoxyphenyl)-4,6,13-trioxatetracyclo[7.7.0.0;{3,7}.0;{11,15}]hexadeca-1,3(7),8-trien-12-one; Furo(3',4':6,7)naphtho(2,3-d)-1,3-dioxol-6(5aH)-one, 5,8,8a,9-tetrahydro-9-hydroxy-5-(3,4,5-trimethoxyphenyl)-, (5R-(5-alpha,5a-alpha,8a-alpha,9-alpha))-; WLN: T E5 C665 FVO NO PO OHTT&&J DR CO1 DO1 EO1& JQ; Picropodophyllin; KBioGR_002538; 5,8,8a,9-Tetrahydro-9-hydroxy-5-(3,4,5-trimethoxyphenyl)furo[3',4':6,7]naphtho[2,3-d]-1,3-dioxol-6(5aH)-one, [5R-(.alpha.-5a.alpha.,8a.alpha.,9.alpha.)]; Insulin-like Growth Factor-1 Receptor Inhibitor; SPECTRUM1504410; KBioSS_002116; BRN 0099161; NSC 36407; SCHEMBL13661743; Spectrum4_001836; IGF-1R Inhibitor, PPP; Spectrum3_001671; KBio2_004684; Lignans; (5R,5aR,8aS,9R)-5-hydroxy-9-(3,4,5-trimethoxyphenyl)-5a,6,8a,9-tetrahydro-5H-isobenzofurano[5,6-f][1,3]benzodioxol-8-one; KBio2_007252; C10871; SDCCGMLS-0066757.P001; Spectrum2_000520; AIDS006792; KBio3_002701; SPBio_000479; Picropodophyllotoxin; CCG-203057; AIDS-006792; KBio2_002116; 17434-18-3; Spectrum5_000631; Furo[3',4':6,7]naphtho[2,3-d]-1,3-dioxol-6(5aH)-one, 5,8,8a,9-tetrahydro-9-hydroxy-5-(3,4,5-trimethoxyphenyl)-, [5R-(5.alpha.,5a.alpha.,8a.alpha.,9.alpha.)]-; Picropodophyllin (8CI); Spectrum_001636; 477-47-4; BSPBio_003481; (5R,8aS,9R)-5-hydroxy-9-(3,4,5-trimethoxyphenyl)-5a,6,8a,9-tetrahydro-5H-[2]benzofuro[5,6-f][1,3]benzodioxol-8-one; NCGC00161923-01; AC1L9DV2; NSC36407
成分:	HBIN039888
OB_score:	51.770219
CAS_id:	477-47-4
SymMap_id:	SMIT00475
TCMID_id:	17323
TCMSP_id:	MOL001710
PubChem_id:	72435

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   化合物对应的植物

植物ID	拉丁名	药用植物名	药名	来源	功能与主治	使用民族

TCMBANKHE000174		八角莲
TCMBANKHE000253	Juniperus thurifera
TCMBANKHE004155	Diphylleia grayi	山荷叶			See Diphylleia sinensis./See Diphylleia sinensis.
TCMBANKHE006215	Podophyllum peltatum	盾叶鬼臼
TCMBANKHE004706	Dysosma aurantiocaulis	多花八角莲
TCMBANKHE004772	Dysosma majorensis	白八角莲			To enrich yin and supplement kidney, clear lung and moisten dryness, resolve toxin and disperse swelling./Taxation damage and sinew bone pain, impotence, stomachache, innominate toxin swelling, knife wound.
TCMBANKHE004916	Bulbus Fritillariae thunbergii	浙贝母			To remove heat and resolve phlegm, to ease the mind, and to reduce modulation./Chronic bronchitis, infection of upper respiratory tract, tuberculosis, gastric ulcer, duodenal ulcer, externally contracted wind-heat, phlegm fire cough, pulmonary welling abscess, mammary welling abscess, scrofula, sore toxin, depression in heart-chest.
TCMBANKHE006974	Diphylleia sinensis	窝儿七			To dispel wind-damp, clear heat and cool blood, quicken blood and relieve pain, drain precipitation./Rheumatic arthritis, pain in lumbus and legs, steaming bone taxation fever, knocks and falls, menstrual disorder, painful bind in lesser-abdomen, swollen welling abscess.
TCMBANKHE008194	Podophyllum emodii	桃儿七			To dispel wind and eliminate damp, quicken blood and relieve pain, relieve cough and dispel phlegm./Wind-damp impediment pain, knocks and falls, menstrual disorder, dysmenorrhea, pain in stomach duct and abdomen, cough.
TCMBANKHE008587	Juniperus sabina	叉子圆柏
TCMBANKHE009095/YNS-1	Dysosma versipellis [Syn. Podophyllum versipelle ]|Dysosma versipellis (Hance) M. cheng ex Ying	鬼臼|八角莲	八角莲	云南药材标准：第一册	清热解毒，化痰散结，祛瘀消肿。用于咳嗽，咽喉肿痛，痈肿痔疮，瘰疬，跌打损伤，毒蛇咬伤。|See Dysosma pleiantha./See Dysosma pleiantha .
TCMBANKHE008322/YNS-1/YEM-371	Dysosma pleiantha [Syn. Podophyllum pleianthum]|Dysosma versipellis (Hance) M. cheng ex Ying|Dysosma veitchii(Hemsl.et Wils.)Fu ex Ying	六角莲|八角莲|川八角莲	八角莲	云南药材标准：第一册|云南民族药物志：第二卷	清热解毒，化痰散结，祛瘀消肿。用于咳嗽，咽喉肿痛，痈肿痔疮，瘰疬，跌打损伤，毒蛇咬伤。|To transform phlegm and dissipate binds, dispel stasis and relieve pain, clear heat and resolve toxin./Cough, swelling pain in throat, scrofula, goiter and tuberculosis, swollen welling abscess, clove sore, poisonous snake bite, knocks and falls, pain in joints.	水族/彝族/壮族
TCMBANKHE006083/YEM-791	Herba Aristolochiae;Fibraurea recisa Pierre|Fibraurea recisa Pierre	天仙藤	大黄藤	云南民族药物志：第四卷	To promote the flow of qi and blood, and to induce diuresis./Acute tonsillitis, pharyngolaryngitis, infection of upper respiratory tract, conjunctivitis, jaundice, gastroenteritis, dysentery, child indigestion, food poisoning, salpingitis, acute endometritis, chronic endometritis, acute pelvic inflammation, vaginitis, sore and boil, burns and scalds.	瑶族/壮族

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   植物对应的疾病

疾病ID	病名	疾病类型	MeSH	参考文献

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   化合物对应的靶点

靶点ID	基因名	基因别名	描述

TCMBANKGE000181	PIM1	PIM	Pim-1 proto-oncogene, serine/threonine kinase
TCMBANKGE000201	ESR1	ER; ESR; ESRA; ESTRR; Era; NR3A1	estrogen receptor 1
TCMBANKGE000205	NOS2	HEP-NOS; INOS; NOS; NOS2A	nitric oxide synthase 2
TCMBANKGE000286	GSK3B	-	glycogen synthase kinase 3 beta
TCMBANKGE000701	ESR2	ER-BETA; ESR-BETA; ESRB; ESTRB; Erb; NR3A2; ODG8	estrogen receptor 2
TCMBANKGE000784	CALM3	CALM; CAM1; CAM2; CAMB; CPVT6; CaM; CaMIII; HEL-S-72; LQT16; PHKD; PHKD3	calmodulin 3
TCMBANKGE000813	DPP4	ADABP; ADCP2; CD26; DPPIV; TP103	dipeptidyl peptidase 4
TCMBANKGE000872	IGF1R	CD221; IGFIR; IGFR; JTK13	insulin like growth factor 1 receptor
TCMBANKGE000979	KDR	CD309; FLK1; VEGFR; VEGFR2	kinase insert domain receptor
TCMBANKGE001073	PTGS2	COX-2; COX2; GRIPGHS; PGG/HS; PGHS-2; PHS-2; hCox-2	prostaglandin-endoperoxide synthase 2
TCMBANKGE001148	VEGFA	MVCD1; VEGF; VPF	vascular endothelial growth factor A
TCMBANKGE004266	AR	AIS; AR8; DHTR; HUMARA; HYSP1; KD; NR3C4; SBMA; SMAX1; TFM	androgen receptor
TCMBANKGE006339	CA2	CA-II; CAC; CAII; Car2; HEL-76; HEL-S-282	carbonic anhydrase 2
TCMBANKGE011079	PRSS1	TRP1; TRY1; TRY4; TRYP1	serine protease 1