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Plant Summary

Plant Information

TCMBank_ID:	TCMBANKHE004916
ID:	TCMBANKHE004916
植物拉丁名:	Bulbus Fritillariae thunbergii
功能与主治:	To remove heat and resolve phlegm, to ease the mind, and to reduce modulation./Chronic bronchitis, infection of upper respiratory tract, tuberculosis, gastric ulcer, duodenal ulcer, externally contracted wind-heat, phlegm fire cough, pulmonary welling abscess, mammary welling abscess, scrofula, sore toxin, depression in heart-chest.
药用植物名:	浙贝母
药用部位:	bulb
药味:	Cold; Bitter
经络:	Lung; Heart
临床特征:	Intraperitioneal administration of its active components, peumine or peiminine, exerts a significant antitussive effect in mice.
治疗类型:	化痰药
TCM_ID_id:	5615
SymMap_id:	481
TCMSP_id:	178

植物对应的化合物

化合物ID	化合物名	别名	分子式	分子质量	Smiles

TCMBANKIN002539	pelargonidin	3,5,7-trihydroxy-2-(4-hydroxyphenyl)-1lambda-chromen-1-ylium; Pelargonidin-3,5-diglucoside_qt; 7690-51-9; C05904; 3,5,7-trihydroxy-2-(4-hydroxyphenyl)chromenylium; XVFMGWDSJLBXDZ-UHFFFAOYSA-O; 3,4',5,7-Tetrahydroxyflavylium; anthocyanidin; pelargonidin 3,5-di-O-glycoside_qt; 3,5,7-trihydroxy-2-(4-hydroxyphenyl)-1-benzopyrylium; CHEBI:25863; 2-(4-hydroxyphenyl)chromenylium-3,5,7-triol; 2-(4-hydroxyphenyl)-1-benzopyrylium-3,5,7-triol; LMPK12010003; CHEMBL591036; pelargonidin-3-O-glucoside_qt; pelargonidin-3,5-di-O-glucoside_qt; BDBM50121994; CHEMBL1197905; A806724; BDBM50326998; 1-Benzopyrylium, 3,5,7-trihydroxy-2-(4-hydroxyphenyl)-; SCHEMBL20592; 134-04-3 (chloride); ZINC391840; Pelargonidin; AC1L9A0P; ZB012073	C15H11O5+	271.24 g/mol	C1=CC(=CC=C1C2=[O+]C3=CC(=CC(=C3C=C2O)O)O)O
TCMBANKIN006996	Ziebeimine	ziebeimine	C27H43NO2	413.64	CC1CCC2C(C3=C(CN2C1)C4CC5C(C4CC3)CC(C6C5(CCC(C6)O)C)O)C
TCMBANKIN007862	peumine
TCMBANKIN009757	trans-communicacid methyl ester		C21H32O2		CC(=CCC1C(=C)CCC2C1(CCCC2(C)C(=O)OC)C)C=C
TCMBANKIN018528	hapepunine 3-o-α-l-rhamnosyl-(1→2)-β-d-glucopyranoside		C40H67NO11
TCMBANKIN020120	Peiminoside	peiminoside	C33H55NO7	577.8 g/mol	CC1CCC2C(C3CCC4C(C3CN2C1)CC5C4CC(C6C5(CCC(C6)OC7C(C(C(C(O7)C)O)O)O)C)O)(C)O
TCMBANKIN022945	peiminine	Peiminine; Raddeamine; Imperialine; Sipeimine; Fritillarine; zhebeinine	C27H43NO3	429.6 g/mol	CC1CCC2C(C3CCC4C(C3CN2C1)CC5C4CC(=O)C6C5(CCC(C6)O)C)(C)O
TCMBANKIN023799	solanidine-3-o-α-l-rhamnopyranosyl-(1→2)-β-d-glucopyranosyl-(1→4)-β-d-glucopyrano-side
TCMBANKIN025202	Chaksine	486-53-3; (3R,7R,11R,15R)-3,11-bis[(4R)-2-amino-4,5-dihydro-3H-imidazol-4-yl]-7,15-dimethyl-1,9-dioxacyclohexadecane-2,10-dione; C09940; 1,9-Dioxacyclohexadecane-2,10-dione, 3,11-bis(2-amino-4,5-dihydro-1H-imidazol-4-yl)-7,15-dimethyl-, (3R-(3R(R),7R,11R(R),15R))-; chaksine; (3R,7R,11R,15R)-3,11-bis[(4R)-2-amino-4,5-dihydro-3H-imidazol-4-yl]-7,15-dimethyl-1,9-dioxacyclohexadecane-2,10-quinone	C22H38N6O4	450.57	CC1CCCC(C(=O)OCC(CCCC(C(=O)OC1)C2CNC(=N2)N)C)C3CNC(=N3)N
TCMBANKIN025398	OSI-2040	NCGC00165733-01; (3S,6S,9S,12R)-6-[(1-methoxyindol-3-yl)methyl]-9-(6-oxooctyl)-3-sec-butyl-1,4,7,10-tetrazabicyclo[10.4.0]hexadecane-2,5,8,11-tetrone; (3S,6S,9S,12R)-3-[(2S)-butan-2-yl]-6-[(1-methoxyindol-3-yl)methyl]-9-(6-oxooctyl)-1,4,7,10-tetrazabicyclo[10.4.0]hexadecane-2,5,8,11-tetrone; (3S,6S,9S,12R)-9-(6-ketooctyl)-6-[(1-methoxyindol-3-yl)methyl]-3-sec-butyl-1,4,7,10-tetrazabicyclo[10.4.0]hexadecane-2,5,8,11-diquinone; (3S,6S,9S,12R)-6-[(1-methoxy-3-indolyl)methyl]-9-(6-oxooctyl)-3-sec-butyl-1,4,7,10-tetrazabicyclo[10.4.0]hexadecane-2,5,8,11-tetrone	C34H49N5O6	623.78	CCC(C)C1C(=O)N2CCCCC2C(=O)NC(C(=O)NC(C(=O)N1)CC3=CN(C4=CC=CC=C43)OC)CCCCCC(=O)CC
TCMBANKIN026871	apicidin	cyclo(N-O-methyl-L-tryptophanyl-L-isoleucinyl-D-pipecolinyl-L-2-amino-8-oxodecanoyl)	C34H49N5O6	623.8 g/mol	CCC(C)C1C(=O)N2CCCCC2C(=O)NC(C(=O)NC(C(=O)N1)CC3=CN(C4=CC=CC=C43)OC)CCCCCC(=O)CC
TCMBANKIN031414	Peiminoside_qt			431.73
TCMBANKIN031607	Pelargonidin-3,5-diglucoside	pelargonidin-3,5-diglucoside	C27H31ClO15	631 g/mol	C1=CC(=CC=C1C2=C(C=C3C(=CC(=CC3=[O+]2)O)OC4C(C(C(C(O4)CO)O)O)O)OC5C(C(C(C(O5)CO)O)O)O)O.[Cl-]
TCMBANKIN036983	trans-communol		C20H32O		CC(=CCC1C(=C)CCC2C1(CCCC2(C)CO)C)C=C
TCMBANKIN037830	Picropodophyllin	(10R,11S,16R)-16-hydroxy-10-(3,4,5-trimethoxyphenyl)-4,6,13-trioxatetracyclo[7.7.0.0;{3,7}.0;{11,15}]hexadeca-1,3(7),8-trien-12-one; Furo(3',4':6,7)naphtho(2,3-d)-1,3-dioxol-6(5aH)-one, 5,8,8a,9-tetrahydro-9-hydroxy-5-(3,4,5-trimethoxyphenyl)-, (5R-(5-alpha,5a-alpha,8a-alpha,9-alpha))-; WLN: T E5 C665 FVO NO PO OHTT&&J DR CO1 DO1 EO1& JQ; Picropodophyllin; KBioGR_002538; 5,8,8a,9-Tetrahydro-9-hydroxy-5-(3,4,5-trimethoxyphenyl)furo[3',4':6,7]naphtho[2,3-d]-1,3-dioxol-6(5aH)-one, [5R-(.alpha.-5a.alpha.,8a.alpha.,9.alpha.)]; Insulin-like Growth Factor-1 Receptor Inhibitor; SPECTRUM1504410; KBioSS_002116; BRN 0099161; NSC 36407; SCHEMBL13661743; Spectrum4_001836; IGF-1R Inhibitor, PPP; Spectrum3_001671; KBio2_004684; Lignans; (5R,5aR,8aS,9R)-5-hydroxy-9-(3,4,5-trimethoxyphenyl)-5a,6,8a,9-tetrahydro-5H-isobenzofurano[5,6-f][1,3]benzodioxol-8-one; KBio2_007252; C10871; SDCCGMLS-0066757.P001; Spectrum2_000520; AIDS006792; KBio3_002701; SPBio_000479; Picropodophyllotoxin; CCG-203057; AIDS-006792; KBio2_002116; 17434-18-3; Spectrum5_000631; Furo[3',4':6,7]naphtho[2,3-d]-1,3-dioxol-6(5aH)-one, 5,8,8a,9-tetrahydro-9-hydroxy-5-(3,4,5-trimethoxyphenyl)-, [5R-(5.alpha.,5a.alpha.,8a.alpha.,9.alpha.)]-; Picropodophyllin (8CI); Spectrum_001636; 477-47-4; BSPBio_003481; (5R,8aS,9R)-5-hydroxy-9-(3,4,5-trimethoxyphenyl)-5a,6,8a,9-tetrahydro-5H-[2]benzofuro[5,6-f][1,3]benzodioxol-8-one; NCGC00161923-01; AC1L9DV2; NSC36407		414.41
TCMBANKIN038909	verticinone	MolPort-006-823-865; Cevan-6-one, 3,20-dihydroxy-, (3beta,5alpha)-; CS-3732; AC1L50EW; 3beta,20-Dihydroxy-5alpha-cevan-6-one; UNII-QUB07U6VTQ; ZINC30727228; C10808; 059P104; Kashmirine; Fritillarine;; Fritillarine; CHEBI:5886; CCG-208360; C-22230; C27H43NO3; AKOS015895686; Verticinone;; Kashmirine;; Q-100214; AC1Q6P7C; QUB07U6VTQ; MFCD00210542; Zhebeinone; Peiminine; AC-7988; 1361-22-4; SCHEMBL5956998; ST51051241; 18059-10-4; 1357-77-3; 1357-21-7; HY-N0213; 1416-43-9; X1200	C27H43NO3	429.64	CC1CCC2C(C3CCC4C(C3CN2C1)CC5C4CC(=O)C6C5(CCC(C6)O)C)(C)O
TCMBANKIN039153	Ebeiensine	3-hydroxy-3',6',10,11b-tetramethylspiro[1,2,3,4,4a,6,6a,6b,7,8,11,11a-dodecahydrobenzo[a]fluorene-9,2'-3a,4,5,6,7,7a-hexahydro-3H-furo[3,2-b]pyridine]-5-one; AC1NSZH8		427.6 g/mol
TCMBANKIN040541	Ebeinone			411.6 g/mol
TCMBANKIN040689	ent-Kaur-15-en-17-ol	Kaur-15-en-17-ol; Ent-kaur-15-en-17-ol; 14696-33-4		288.47
TCMBANKIN041404	isobaimonidine		C27H45NO3
TCMBANKIN041435	ent-Kauran-16β,17-diol
TCMBANKIN041581	ent-16α-Methoxy-kauran-17-ol	ent-16alpha-methoxy-kauran-17-ol
TCMBANKIN042548	ent-Kauran-16α,17-diol
TCMBANKIN042997	fritillarizine	STOCK1N-49967; AKOS030501866; 76733-86-3; ZINC70688102; BG01702139; MCULE-6057699517; (1R,2S,6S,9S,10S,11S,14S,15S,20R,23R,24S)-6,10,23-TRIMETHYL-4-AZAHEXACYCLO[12.11.0.0(2),(1)(1).0?,?.0(1)?,(2)?.0(1)?,(2)(3)]PENTACOS-17-ENE-10,20-DIOL; MolPort-002-524-349	C27H43NO2	413.6 g/mol	CC1CCC2C(C3CCC4C5CC=C6CC(CCC6(C5CC4C3CN2C1)C)O)(C)O
TCMBANKIN043095	Zhebeininoside
TCMBANKIN043389	verticinone-n-oxide
TCMBANKIN045336	Hapepunine	AC1O3DF4; 68422-01-5; (3S,8S,9S,10R,13S,14S,16S)-17-[(1S)-1-(1,5-dimethylpiperidin-2-yl)ethyl]-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene-3,16-diol		429.7 g/mol
TCMBANKIN045520	solanidine-3-o-α-l-rhamnopyranosyl-(1→2)-β-d-glucopyranoside
TCMBANKIN046426	baimonidine		C27H45NO3
TCMBANKIN046779	ent-17-norkauran-16-one		C19H30O	274.44	CC1(CCCC2(C1CCC34C2CCC(C3)C(=O)C4)C)C
TCMBANKIN049013	ent-(16S)-atisan-13,17-oxide	ent-(16s)-atisan-13,17-oxide	C20H32O	288.47	CC1(CCCC2(C1CCC34C2CC5C(C3)COC5C4)C)C
TCMBANKIN058450	ADO	nchembio.2007.56-comp13; CHEBI:16335; Bio1_000437; 9-beta-D-Ribofuranosyl-9H-purin-6-amine; AIDS-001224; 9beta-D-Ribofuranosyladenine; BSPBio_001796; beta-Adenosine; (2R,3R,4S,5R)-2-(6-aminopurin-9-yl)-5-methylol-tetrahydrofuran-3,4-diol; beta-D-Ribofuranoside, adenine-9; D00045; 46969-16-8; SDCCGMLS-0003108.P003; 4-Aminopyrazolo[3,4-d]pyrimidine ribonucleoside; (2R,3R,4S,5R)-2-(6-aminopurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol; 6-Amino-9-.beta.-ribofuranosyl-9H-purine; NSC 7652; Bio1_001415; Adenosine (JAN/USP); Spectrum2_001257; Spectrum3_000288; Adenosine, homopolymer; ADN; Caswell No. 010B; Adenocard; C00212; SR 96225; Adenocard (TN); EINECS 200-389-9; KBio3_001296; 9H-Purin-6-amine, 9beta-D-ribofuranosyl-; Polyadenosine; beta-D-Ribofuranose, 1-(6-amino-9H-purin-9-yl)-1-deoxy-; (2R,3R,4S,5R)-2-(6-amino-9-purinyl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol; MLS000069638; AI3-52413; 9-beta-D-Ribofuranosidoadenine; A9251_SIGMA; Adenoscan (TN); Bio1_000926; ZINC02169830; CCRIS 2557; NCGC00023673-05; Ade-Rib; nchembio706-5; 30143-02-3; 6-Amino-9-beta-D-ribofuranosyl-9H-purine; Adenosin [German]; NSC 627048; SMR000058216; 9-beta-D-Ribofuranosyladenine; SPBio_001194; beta-D-Adenosine; Adenosine [USAN:BAN]; Polyriboadenosine; (2R,3R,4S,5R)-2-(6-aminopurin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol; AIDS001224; 6-Amino-9beta-D-ribofuranosyl-9H-purine; ST009496; Adenoscan; A4036_SIGMA; SPECTRUM1500107; 46946-45-6;SCHEMBL170902; adenosine ; AKOS015960342; AC-5504; BC200893; Adenosine;adenosine;adeninenucleoside	C10H13N5O4	267.24 g/mol	C1=NC(=C2C(=N1)N(C=N2)C3C(C(C(O3)CO)O)O)N
TCMBANKIN059668	16, 17-epoxykaurane		C20H32O	288.47	CC1(CCCC2(C1CCC34C2CCC(C3)C5(C4)CO5)C)C
TCMBANKIN060039	THM		C10H14N2O5	242.23 g/mol	CC1=CN(C(=O)NC1=O)C2CC(C(O2)CO)O
TCMBANKIN060044	5-methyluracil		C5H6N2O2	126.11 g/mol	CC1=CNC(=O)NC1=O
TCMBANKIN060385	(16r)-ent-7β-hydroxykauran-15-one		C20H32O2		CC1C2CCC3C4(CCCC(C4CC(C3(C2)C1=O)O)(C)C)C
TCMBANKIN060428	Peimisine		C27H41NO3	427.6 g/mol	CC1CC2C(C(C3(O2)CCC4C5CC(=O)C6CC(CCC6(C5CC4=C3C)C)O)C)NC1
TCMBANKIN060578	Solanidine		C27H43NO	397.6 g/mol	CC1CCC2C(C3C(N2C1)CC4C3(CCC5C4CC=C6C5(CCC(C6)O)C)C)C
TCMBANKIN060582	Verticine		C27H45NO3	431.7 g/mol	CC1CCC2C(C3CCC4C(C3CN2C1)CC5C4CC(C6C5(CCC(C6)O)C)O)(C)O
TCMBANKIN061761	Zhebeiresinol	zhebeiresinol;caruilignan d	C14H16O6	280.27	COC1=CC(=CC(=C1O)OC)C2C3COC(=O)C3CO2
TCMBANKIN061762	syringaresinol	(+)-Suyringaresinol-di-O-beta-D-glucoside_qt; (+)syringaresinol; (+)-Suyringaresinol-di-O-beta-D-glucoside; liriodendrin_qt; dl-Syringaresinol; syringaresinol diglucoside_qt; dl-sy-ringaresinol; (+)-syringaresinol-O-β-D-glucopyranoside; (+ )-syringaresinol; 4-[(1S,3aR,4S,6aR)-4-(4-hydroxy-3,5-dimethoxy-phenyl)-1,3,3a,4,6,6a-hexahydrofuro[4,3-c]furan-1-yl]-2,6-dimethoxy-phenol; 21453-69-0; C10889; (7alpha,7'alpha,8alpha,8'alpha)-3,3',5,5'-tetramethoxy-7,9':7',9-diepoxylignane-4,4'-diol; CHEBI:47; 4-[(1S,3aR,4S,6aR)-4-(4-hydroxy-3,5-dimethoxyphenyl)-1,3,3a,4,6,6a-hexahydrofuro[4,3-c]furan-1-yl]-2,6-dimethoxyphenol; (+)-syringaresinol; (+ )- syringaresinol; dl-syringaresinol; (-)-syringaresinol; episyringaresinol; (+)-syringarosinol; (+ )-Syringaresinol-O-β-D-glucopyranoside; syringaresino; (-)-syringaresinol; (?)-syringaresinol; (+)-Syringaresinol; lirioresinol-A	C34H46O18	742.72	COC1=CC(=CC(=C1O)OC)C2C3COC(C3CO2)C4=CC(=C(C(=C4)OC)O)OC

植物对应的疾病

疾病ID	病名	疾病类型	MeSH	参考文献

植物对应的靶点

靶点ID	基因名	基因别名	描述	染色体位置	Map_Location	基因类型

TCMBank_ID:

TCMBANKHE004916

ID:

TCMBANKHE004916

植物拉丁名:

Bulbus Fritillariae thunbergii

功能与主治:

药用植物名:

浙贝母

药用部位:

bulb

药味:

Cold; Bitter

经络:

Lung; Heart

临床特征:

Intraperitioneal administration of its active components, peumine or peiminine, exerts a significant antitussive effect in mice.

治疗类型:

化痰药

TCM_ID_id:

5615

SymMap_id:

481

TCMSP_id:

178