Compound Summary


  Compound Information

药名:

Germacrene D

别名:

C16142; (1E,6E,8S)-8-isopropyl-1-methyl-5-methylenecyclodeca-1,6-diene; (1E,6E,8S)-8-isopropyl-1-methyl-5-methylene-cyclodeca-1,6-diene; germacrene-d; (-)-Germacrene D; (1E,6E,8S)-1-methyl-5-methylidene-8-propan-2-yl-cyclodeca-1,6-diene; germacrene d; Germacrene- D; GermacreneD; (1E,6E,8S)-1-methyl-5-methylidene-8-propan-2-ylcyclodeca-1,6-diene; nchembio.2007.29-comp4

分子式:

C15H24

Smiles:

C1([H])([H])C(=C([H])[H])\C([H])=C([H])\[C@]([H])(C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])\C(\C([H])([H])[H])=C([H])\C1([H])[H]

成分:

HBIN027568

OB_score:

19.222506

CAS_id:

23986-74-5

SymMap_id:

SMIT05260

TCMID_id:

8343;34829;35531;29446

TCMSP_id:

MOL003127

PubChem_id:

5317570


   化合物对应的植物
植物ID 拉丁名 药用植物名 药名 来源 功能与主治 使用民族
TCMBANKHE000022 Echinacea purpurea 紫锥花 Used as a general nonspecific stimulant to the immune system, supporting and stabilizing cellular immunity and cleansing the blood, for the prevention and treatment of infections. There are no known side effects associated with it's use./Used as a general nonspecific stimulant to the immune system, supporting and stabilizing cellular immunity and cleansing the blood, for the prevention and treatment of infections. There are no known side effects associated with it's use.
TCMBANKHE000081 柚花
TCMBANKHE000214 Rhizoma Curcumae 莪术 To promote the flow of qi and eliminate blood stasis with strong effect, and to relieve pain by removing the stagnation of undigested food./1. Its volatile oil and its components curcumenol, curdione and B-elemene destroy directly the Ehrlich-Ascites tumor and leukemia615 in mice. 2. Promoting phagocytosis of monocytes. 3. Dilating peripheral blood vessels, inhibiting aggregation of thrombocytes and thrombosis, and improving microcirculation.
TCMBANKHE000735 Exodermis Poria 茯苓皮 Treatment of edema with oliguria, dizziness and palpitation caused by retained fluid, diminished function of the spleen marked by anorexia, loose stools or diarrhea, restlessness and insomnia./1. An active component pachyman promotes macrophage phagocytosis in mice, and enhances lymphocyte-blastogensis rate in vitro.2. Preventing the formation of gastric ulcer under stress in rats3. Diuretic and liver-protective.
TCMBANKHE002205 Fructus Perillae 紫苏子 To relieve dyspnea and cough, to eliminate phlegm , and to relax bowels./Treatment of cough and dyspnea due to accumulation of phleg , constipation.
TCMBANKHE002350 芫荽
TCMBANKHE002542 Fructus Schiandrae 北五味 Treatment of chronic cough and asthma, nocturnal emission, spermatorrhea, enuresis, frequent urination, protracted diarrhea, spontaneous sweating, night sweating, impairment of body fluid with thirst, shortness of breath and feeble pulse, diabetes caused by internal heat, palpitation and insomnia./1. Its decoction exerts bacteriostatic effect on Pseudomonas aeruginosa (1:128), Staphylococcus aureus (1:64), Flexner's bacillus (1:32) and typhoid bacillus (1:8) in vitro.2. Schizandrin, one of its active components, can protect the liver from damage.3. Enhancing lymphocyte-blastogenesis rate.4. Cardiotonic and sedative.
TCMBANKHE003718 Flos Chrysanthemi 菊花 To dispel wind-heat, to subdue hyperactivity of the liver, and improve eyesight./Angina pectoris, hypertension, externally contracted wind-heat, wind warmth, fever and headache, dizziness, common cold, red eyes, red eyes with gall, swelling toxin of clove sore.
TCMBANKHE003723 Flos Lonicerae 金银花 To remove toxic heat and dispel wind-heat./Infection of upper respiratory tract, tonsillitis, acute laryngitis, skin suppurations, welling abscess, viral conjunctivitis, influenza, pneumonia, mastitis, acute appendicitis, warm disease fever, heat toxin blood dysentery, swollen welling abscess and clove sores, throat impediment.
TCMBANKHE003725 Rhizoma Zingiberis Recens 生姜 To induce perspiration and dispel cold, to warm the stomach and arret vomiting, and to resolve phlegm and relieve cough./Wind-cold common cold, fever and aversion to wind, headache and nasal congestion, vomiting, phlegm-rheum cough asthma, distention fullness, diarrhea.
TCMBANKHE003746 Radix Scutellariae 黄芩 To remove damp-heat, to quench fire and counteract toxicity, to arrest bleeding, and to prevent abortion./Chest oppression with retching, diarrhea, jaundice, lung heat cough, infection of upper respiratory tract, acute tonsillitis, acute pharyngolaryngitis, ardent fever with vexation and thirst, blood heat, blood ejection, spontaneous external bleeding, swelling toxin of welling abscess and sore, stirring fetus in pregnancy.
TCMBANKHE003752 Radix Salviae liguliobae 丹参 To remove blood stasis and relieve pain, to promote the flow of blood and stimulate menstrual discharge, and to ease the mind./Angina pectoris, cerebral atherosclerosis, diffusive intravascular clotting, thrombophlebitis, hepatitis, acute surgical infection, mastitis, erysipelas, otitis media, tonsillitis, bone marrow infection, menstrual disorder, dysmenorrhea, amenorrhea, postpartum stasis stagnation abdominal pain, pain in heart and abdomen, concretion conglomeration accumulation and gathering, heat impediment swelling and pain, knocks and falls, heat entering construction-blood, vexation and agitation, insomnia and vexation, swelling toxin of welling abscess and sore, zoster, neurodermatitis, psoriasis.
TCMBANKHE003909 Cryptotaenia japonica 鸭儿芹 To resolve toxin and eliminate inflammation, quicken blood and disperse swelling./Pneumonia, pulmonary welling abscess, strangury, mounting qi, wind-fire toothache, welling abscess and clove sore, zoster, itchy skin.
TCMBANKHE003940 Herba Elsholtziae;Haichow Elsholtzia;Mosla chinensis 香薷 1. To promote diaphoresis and release the exterior; 2. To resolve dampness and harmonize the spleen and stomach; 3. To promote water metabolism and release edema/Fever, aversion of cold, headache, absence of sweating, abdominal pain, vomiting and diarrhea, edema and inhibited urination, beriberi.
TCMBANKHE003943 Herba Cirsii Japonici;Radix Cirsii Japonici;Herba seu Radix Cirsii japonici 大蓟 To arrest bleeding by reducing heat in the blood, to remove blood stasis, and to promote the subsidence of swelling.;Treatment of epistaxis, spitting of blood, hematuria, hematochezia, abnormal uterine bleeding, traumatic bleeding, carbuncles and sores./1. Its decoction can lower blood pressure2. Inhibiting the growth of (a)-streptococcus3. Shortening the bleeding time.4. Anti-inflammatory5. Diuretic.
TCMBANKHE007765 覆盆子 Impotence with premature ejaculation, emission, infertility due to uterus cold, frequent urination and enuresis, dizziness and dim vision, premature graying in beard and hair.
TCMBANKHE005760 Craibiodendron yunnanese 金椰子 To dispel wind and quicken blood, free network vessels and relieve pain./Impediment pain, hemiplegia, knocks and falls.
TCMBANKHE004172 Radix Bupleuri 柴胡 To relieve fever, to soothe the liver, and to cure drooping and ptosis./Common cold, influenza, malaria, acute pancreatitis, pleuritis, neuritis, gastritis, acute cholecystitis, hepatitis, fever due to external contraction, keratitis, cold-heat in turn, liver depression and rib-side pain, mammary distention, dizziness and headache, menstrual disorder, prolapse of rectum due to qi vacuity fall, prolapse of uterus, gastroptosis.
TCMBANKHE005959 Teucrium bidentatum 二齿香科科 To dispel wind, disinhibit damp, resolve toxin./Common cold, headache, nasal congestion, dysentery, eczema, eczema leukoplakia.
TCMBANKHE004912 Flos Caryophylli 丁香 To warm the spleen and stomach, to regulate the adverse flow of the stomach qi, and to restore the kidney yang./Stomach cold with retching counterflow, hiccough, cold pain in stomach duct and abdomen, reduced food intake and diarrhea, kidney vacuity impotence, vacuity cold in lumbus and knees, yin flat abscess.
TCMBANKHE007157 Magnolia coco 夜合花 To move qi and dissipate stasis, relieve cough, check discharge./Liver depression and qi pain, knocks and falls, concretion and conglomeration, Vaginal discharge.
TCMBANKHE007269 Fructus Viticis 蔓荆子 To dispel wind-heat from the head and eyes./Externally contracted wind-heat, dizziness and headache, migraine, gum swelling and pain, red eyes with gall, delacrimation, wind-damp impediment pain, hypertonicity of limbs.
TCMBANKHE006133 紫苏 Phlegm congestion and qi counterflow, cough and asthma, intestinal dry and constipation.
TCMBANKHE005793 Flos Chrysanthemi 菊花 To dispel wind-heat, to subdue hyperactivity of the liver, and improve eyesight./Angina pectoris, hypertension, externally contracted wind-heat, wind warmth, fever and headache, dizziness, common cold, red eyes, red eyes with gall, swelling toxin of clove sore.
TCMBANKHE006054 Radix chuanxiong;Rhizoma Chuanxiong 川芎 1. To invigorate blood and promote qi circulation; 2. To expel wind and stop pain/Cerebral ischemia, postpartum pain, acute icterohepatitis, menstrual disorder, amenorrhea and dysmenorrhea, concretion and conglomeration, chest and rib-side stabbing pain, painful swelling from knocks and falls, headache, wind-damp impediment pain.
TCMBANKHE009036 Cacumen et Folium Biotae 侧柏叶 To arrest bleeding by removing heat from blood, and to promote the growth of black hair./Hemoptysis, duodenal bleeding, chronic bronchitis, tuberculosis, blood ejection, spontaneous external bleeding, hematuria, hematochezia, blood dysentery, incessant flooding and spotting, cough with profuse phlegm, wind-damp impediment pain, erysipelas, epidemic parotitis, scalds, burns.
TCMBANKHE008601 Ixora chinensis 龙船花 To clear heat and cool blood, dissipate stasis and relieve pain./Hypertension, menstrual disorder, amenorrhea, knocks and falls, swelling of sores and boils.
TCMBANKHE007781 Herba Asari 细辛 To dispel wind-cold, to relieve nasal obstruction, to alleviate pain and to remove retained fluid./Wind-cold common cold, influenza, headache, toothache, local anesthesia, nasal congestion, deep-source nasal congestion, wind-damp impediment pain, phlegm-rheum cough asthma.
TCMBANKHE006919 flos farfarae 款冬花 To relieve cough and resolve phlegm to nourish the lung to keep the adverse qi downward./Cough, cough and asthma with abundant phlegm, consumption cough and hemoptysis, chronic bronchitis, infection of upper respiratory tract, tuberculosis.
TCMBANKHE007514 Acanthopanax giraldii [Syn. Acanthopanax giraldii var. inermis , Eleutherococcus giraldii] 红毛五加皮 To dispel wind-damp, strengthen sinews and bones, quicken blood and disinhibit water./Wind-cold-damp impediment, hypertonicity and pain, limp wilting sinew and bone, inability of legs and knees, pain in heart and abdomen, mounting qi [=hernia], knocks and falls, fracture, vacuity and edema.
TCMBANKHE008104 Radix chuanxiong;Rhizoma Chuanxiong 川芎 1. To invigorate blood and promote qi circulation; 2. To expel wind and stop pain/Cerebral ischemia, postpartum pain, acute icterohepatitis, menstrual disorder, amenorrhea and dysmenorrhea, concretion and conglomeration, chest and rib-side stabbing pain, painful swelling from knocks and falls, headache, wind-damp impediment pain.
TCMBANKHE009030 Resi myrrhae;Myrrha 没药 1. To invigorate blood and stop pain; 2. To reduce swelling and promote healing/Stasis pain in chest and abdomen, amenorrhea, dysmenorrhea, concretion and conglomeration, knocks and falls, swollen welling abscess and sores, intestinal welling abscess, red eyes with gall.
TCMBANKHE008995 Citrus junos 橙子皮 To transform phlegm, disinhibit diaphragm, disperse food, check vomiting./Qi stagnation in chest and diaphragm, cough with profuse phlegm, non-digestion of food accumulation, nausea and vomiting, drunkenness.
TCMBANKHE005980/YEM-13 herba Menthae;Mentha haplocalyx Briq|Mentha haplocalyx Briq. 薄荷 薄荷 云南民族药物志:第一卷 To dispel wind-heat from the head and eyes, and to promote eruption./Chronic urticaria, infection of upper respiratory tract, sarcoma, wind-heat exterior syndrome, headache and red eyes, swelling pain in throat, non-eruption of measles, dormant papules with pruritus, liver depression and rib-side pain, abdominal distention. 阿昌族/傣族/德昂族/哈尼族/景颇族/傈僳族/彝族
TCMBANKHE004506/YEM-137 Radix Notoginseng|Panax notoginseng (Burk.) F, H. Chen ex C.Chow et al. 三七 三七 云南民族药物志:第一卷 To eliminate blood stasis, arrest bleeding, cause subsidence of swelling and alleviate pain./Hemoptysis, blood ejection, spontaneous external bleeding, hematochezia, flooding and spotting, bleeding due to external injury, angina pectoris, stabbing pain in chest and abdomen, painful swelling from knocks and falls. 彝族
TCMBANKHE005671/YEM-254 Radix Dichroae|Dichroa febrifuga Lour. 常山 常山 云南民族药物志:第二卷 To expel phlegm and relieve malaria/Malaria, scrofula. 阿昌族/傣族/德昂族/哈尼族/基诺族/景颇族/拉祜族/苗族/佤族/瑶族/彝族
TCMBANKHE005199/YEM-416/XU-321 Fructus Xanthii sibirici|Xanthium sibiricum Patrin ex Widder|Xanthium sibiricum 苍耳子|苍耳 苍耳子 云南民族药物志:第二卷|贵州省毕节市赫章县 To dispel wind and damp, and to relieve nasal obstruction./1. Lowering blood sugar, with similar mechanism as phenethyl biguanide ( DBI ). 2. Its chief poisonous component is rhamnose. The toxic effects in rats, guinea-pigs and rabbits by different routes of administration are similar. LD50 is 0.93g/kg in mice. 阿昌族/白族/傣族/德昂族/哈尼族/景颇族/傈僳族/苗族/彝族/藏族
TCMBANKHE005416/YEM-639/XU-540 Cortex Toonae Sinensis|Ailanthus altissima(Mill.)Swingle|Ailanthus altissima 椿根皮,椿皮|臭椿 臭椿 云南民族药物志:第四卷|云南省大理州下关 Treatment of morbid leukorrhea, diarrhea caused by damp-heat, chronic diarrhea, chronic dysentery, hematochezia, abnormal uterine bleeding, to remove damp-heat and arrest discharges./Treatment of morbid leukorrhea, diarrhea caused by damp-heat, chronic diarrhea, chronic dysentery, hematochezia, abnormal uterine bleeding. 瑶族/彝族

   植物对应的疾病
疾病ID 病名 疾病类型 MeSH 参考文献

   化合物对应的靶点
靶点ID 基因名 基因别名 描述
TCMBANKGE000476 NCOA2 GRIP1; KAT13C; NCoA-2; SRC2; TIF2; bHLHe75 nuclear receptor coactivator 2
TCMBANKGE000766 ACHE ACEE; ARACHE; N-ACHE; YT acetylcholinesterase (Cartwright blood group)
TCMBANKGE000813 DPP4 ADABP; ADCP2; CD26; DPPIV; TP103 dipeptidyl peptidase 4
TCMBANKGE000903 PTGS1 COX1; COX3; PCOX1; PES-1; PGG/HS; PGHS-1; PGHS1; PHS1; PTGHS prostaglandin-endoperoxide synthase 1
TCMBANKGE001073 PTGS2 COX-2; COX2; GRIPGHS; PGG/HS; PGHS-2; PHS-2; hCox-2 prostaglandin-endoperoxide synthase 2
TCMBANKGE009256 SLC6A2 NAT1; NET; NET1; SLC6A5 solute carrier family 6 member 2
TCMBANKGE011079 PRSS1 TRP1; TRY1; TRY4; TRYP1 serine protease 1