Compound Summary
Compound Information
药名: | fisetin |
别名: | Spectrum4_001070; BSPBio_002952; ST057233; C.I. 75620; NSC407010; Superfustel K; Viset; ZINC00039111; CHEBI:42567; 2-(3,4-dihydroxyphenyl)-3,7-dihydroxy-chromone; NCI60_003865; Fisetin; Fietin; KBio1_001500; TNP00004; 2-(3,4-DIHYDROXYPHENYL)-3,7-DIHYDROXY-4H-CHROMEN-4-ONE; 5-Desoxyquercetin; Fisetin; 5-Deoxyquercetin; 3,3?,4?,7-Tetra??hydroxy??flavone; Natural Brown 1; 3,7-Dihydroxy-2-(3,4-dihydroxyphenyl)-4H-1-benzopyran-4-one; SPECTRUM1502247; NSC 656275; NCIMech_000006; C10041; Ventin sumach; AIDS-003057; NCGC00017344-02; 3,3',4',7-Tetrahydroxyflavone; KBio2_006812; Spectrum3_001536; KBio2_004244; SDCCGMLS-0066657.P001; SPBio_001119; Spectrum2_001160; Spectrum5_001797; 3,7,3',4'-TETRAHYDROXYFLAVONE; DivK1c_006556; 5-18-05-00291 (Beilstein Handbook Reference); Superfustel; EINECS 208-434-4; SpecPlus_000460; Cotinin; 528-48-3; NCGC00017344-01; Young fustic; KBioGR_001400; S00056; NSC656275; AIDS003057; KBioSS_001676; Bois bleu de Honqrie; FLAVONE, 3,3',4',7-TETRAHYDROXY-; Young fustic crystals; 2-(3,4-dihydroxyphenyl)-3,7-dihydroxy-4-chromenone; 2-(3,4-Dihydroxyphenyl)-3,7-dihydroxy-4H-1-benzopyran-4-one; 2-(3,4-dihydroxyphenyl)-3,7-dihydroxychromen-4-one; Spectrum_001196; Fustel; 2-(3,4-dihydroxyphenyl)-3,7-dihydroxy-chromen-4-one; 4H-1-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-3,7-dihydroxy-; TNP00284; C.I. Natural Brown 1; Ungarisches gelbholz; NCGC00095663-02; Junger fustik; fisetin ; KBio2_001676; 7,3',4'-Trihydroxyflavonol; KBio3_002452; BOIS bleude honqrie; NCGC00095663-01; InChI=1/C15H10O6/c16-8-2-3-9-12(6-8)21-15(14(20)13(9)19)7-1-4-10(17)11(18)5-7/h1-6,16-18,20; BRN 0292829; Fisetholz; CHEBI:71992; Fustet; NSC 407010; FSE; 3,3'4'7-tetOH-Flavone; Zante fustic; 3,7,3 ', 4'-tetrahydroxy-flavone |
分子式: | C15H10O6 |
Smiles: | C1=CC(=C(C=C1C2=C(C(=O)C3=C(O2)C=C(C=C3)O)O)O)O |
成分: | HBIN026506;HBIN007761 |
OB_score: | 52.595671 |
CAS_id: | 528-48-3 |
SymMap_id: | SMIT00327 |
TCMID_id: | 7801;42070 |
TCMSP_id: | MOL013179 |
PubChem_id: | 5281614 |
化合物对应的植物
| 植物ID | 拉丁名 | 药用植物名 | 药名 | 来源 | 功能与主治 | 使用民族 |
|---|
| TCMBANKHE004862 | Lignum Dalbergiae odoriferae Rosewood | 降香 | To relieve pain by promoting the circulation of qi and blood, and to arrest bleeding./Shortening the plasma recalcification time in rabbits. | |||
| TCMBANKHE004891 | Pistacia chinensis | 黄连芽 | To clear summerheat, engender liquid, resolve toxin, disinhibit damp./Summerheat-heat thirst, swelling pain in throat, oral ulcer, vomiting and dysentery, strangury syndrome, innominate toxin swelling, sore and papules. | |||
| TCMBANKHE004973 | Herba Ephedrae | 麻黄 | To induce perspiration for dispelling cold, to relieve asthma, and to cause diuresis./Wind-cold exterior repletion syndrome, headache without sweating, headache and generalized pain, cough, fever, fever and aversion to wind, absence of sweating, congesting lung, non-diffusion of lung qi, cough and asthma, bronchial asthma, wind water edema, nasal congestion, allergic rhinitis, inhibited urination, wind-damp impediment pain, muscle numbness, wind papule itching, yin flat abscess and phlegm node. | |||
| TCMBANKHE007767 | Semen Cavaliae | 刀豆 | To warm the stomach and check its upward adverse movement./Vacuity cold and hiccough, vomiting. | |||
| TCMBANKHE006308 | Seriphidium finitum [Syn. Artemisia finita] | 东北蛔蒿 | To expel worms./Ascariasis, oxyuria disease. | |||
| TCMBANKHE005874 | 玳玳花 | Oppression in chest due to glomus, distending pain in stomach duct and abdomen, vomiting, reduced food intake. | ||||
| TCMBANKHE007965 | Anthyllis vulneraria | 疗伤绒毛花 | ||||
| TCMBANKHE007219 | Rhus sylvestris | 野漆树叶 | To dispel stasis and disperse swelling, kill worms, resolve toxin./Knocks and falls, bleeding due to external injury, ancylostomiasis, scab and lichen, sore toxin, poisonous snake bite. | |||
| TCMBANKHE009050 | Toxicodendron succedaneum [Syn. Rhus succedanea ] | 林背子 | To stanch bleeding and dissipate stasis, resolve toxin./Hemoptysis, blood ejection, bleeding due to external injury, poisonous snake bite. | |||
| TCMBANKHE007551 | Catechu | 儿茶 | To reduce toxic and to remove dampness./To arrest exudation, promote the growth of new tissue, and cure wounds. | |||
| TCMBANKHE005899/XU-345 | Spina gleditsiae;Spi gleditsiae|Gleditsia sinensis | 皂刺;皂角刺|皂荚 | 云南省曲靖市会泽县 | Treatment of carbuncle and boil at the early stage or formation of abscess difficult to burst, external use for scabies and leprosy. /1. To relieve carbuncle and drain pus. For the early stage of carbuncle or carbuncle with unruptured abscess. 2. To expel wind and kill parasites. For tinea infection and leprosy. | ||
| TCMBANKHE003860/YEM-41 | Acacia catechu|Acacia catechu (L.f.) Willd. | 孩儿茶|儿茶 | 儿茶 | 云南民族药物志：第一卷 | To contract damp, close sores and engender flesh./Enduring sores, eczema, mouth sore, painful wound from knocks and falls, bleeding due to external injury, suppurative infection. | 阿昌族/傣族/德昂族/景颇族/傈僳族/彝族/藏族 |
| TCMBANKHE006555/YEM-691 | Mangifera indica|Mangifera indica L. | 杧果 | 杧果 | 云南民族药物志：第四卷 | To boost stomach, engender liquid, check vomiting, relieve cough./Thirst, vomiting, reduced food intake, cough. | 阿昌族/傣族/德昂族/景颇族/傈僳族/佤族/彝族/藏族/壮族 |
植物对应的疾病
| 疾病ID | 病名 | 疾病类型 | MeSH | 参考文献 |
|---|
| TCMBANKDI000018 | Pancreatic Neoplasm | disease | Digestive System Diseases; Neoplasms; Endocrine System Diseases | 30760707 |
| TCMBANKDI000047 | Neoplasm Metastasis | phenotype | Pathological Conditions, Signs and Symptoms; Neoplasms | 31438640 |
| TCMBANKDI000069 | Bone neoplasms | group | Neoplasms; Musculoskeletal Diseases | 29270805 |
| TCMBANKDI000070 | Osteosarcoma | disease | Neoplasms | 29270805 |
| TCMBANKDI000085 | Inflammation | phenotype | Pathological Conditions, Signs and Symptoms | 31540162 |
| TCMBANKDI002310 | Kidney Neoplasm | disease | Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases | 31438640 |
| TCMBANKDI012631 | Renal Cell Carcinoma | disease | Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases | 31438640 |
| TCMBANKDI022179 | Longevity | phenotype | - | 30279143 |
| TCMBANKDI023482 | Psoriasis | disease | Skin and Connective Tissue Diseases | 31540162 |
化合物对应的靶点
| 靶点ID | 基因名 | 基因别名 | 描述 |
|---|
| TCMBANKGE000046 | PIK3R1 | AGM7; GRB1; IMD36; p85; p85-ALPHA | phosphoinositide-3-kinase regulatory subunit 1 |
| TCMBANKGE000047 | AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | AKT serine/threonine kinase 1 |
| TCMBANKGE000051 | IL1B | IL-1; IL1-BETA; IL1F2; IL1beta | interleukin 1 beta |
| TCMBANKGE000052 | TNF | DIF; TNF-alpha; TNFA; TNFSF2; TNLG1F | tumor necrosis factor |
| TCMBANKGE000053 | NFKB1 | CVID12; EBP-1; KBF1; NF-kB; NF-kB1; NF-kappa-B1; NF-kappaB; NF-kappabeta; NFKB-p105; NFKB-p50; NFkappaB | nuclear factor kappa B subunit 1 |
| TCMBANKGE000240 | IL17A | CTLA-8; CTLA8; IL-17; IL-17A; IL17 | interleukin 17A |
| TCMBANKGE000256 | PRKCA | AAG6; PKC-alpha; PKCA; PKCI+/-; PKCalpha; PRKACA | protein kinase C alpha |
| TCMBANKGE000288 | ATF6 | ACHM7; ATF6A | activating transcription factor 6 |
| TCMBANKGE000289 | EIF2AK3 | PEK; PERK; WRS | eukaryotic translation initiation factor 2 alpha kinase 3 |
| TCMBANKGE000291 | NSG1 | D4S234; D4S234E; NEEP21; P21 | neuronal vesicle trafficking associated 1 |
| TCMBANKGE000292 | TCEAL1 | SIIR; WEX9; p21; pp21 | transcription elongation factor A like 1 |
| TCMBANKGE000293 | TPT1 | HRF; TCTP; p02; p23 | tumor protein, translationally-controlled 1 |
| TCMBANKGE000294 | CDKN1A | CAP20; CDKN1; CIP1; MDA-6; P21; SDI1; WAF1; p21CIP1 | cyclin dependent kinase inhibitor 1A |
| TCMBANKGE000305 | PIK3CD | APDS; IMD14; P110DELTA; PI3K; p110D | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta |
| TCMBANKGE000306 | PIK3CG | PI3CG; PI3K; PI3Kgamma; PIK3; p110gamma; p120-PI3K | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma |
| TCMBANKGE000307 | PIK3CB | P110BETA; PI3K; PI3KBETA; PIK3C1 | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta |
| TCMBANKGE000308 | PIK3CA | CLAPO; CLOVE; CWS5; MCAP; MCM; MCMTC; PI3K; PI3K-alpha; p110-alpha | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha |
| TCMBANKGE000591 | NUPR1 | COM1; P8 | nuclear protein 1, transcriptional regulator |
| TCMBANKGE000592 | PPP1CC | PP-1G; PP1C; PPP1G | protein phosphatase 1 catalytic subunit gamma |
| TCMBANKGE000593 | PPA1 | HEL-S-66p; IOPPP; PP; PP1; SID6-8061 | inorganic pyrophosphatase 1 |
| TCMBANKGE000594 | ZNRD2 | SSSCA1; p27 | zinc ribbon domain containing 2 |
| TCMBANKGE000595 | ADAM9 | CORD9; MCMP; MDC9; Mltng | ADAM metallopeptidase domain 9 |
| TCMBANKGE000596 | PSMD9 | Rpn4; p27 | proteasome 26S subunit, non-ATPase 9 |
| TCMBANKGE000597 | TMED7 | CGI-109; p24g3; p24gamma3; p27 | transmembrane p24 trafficking protein 7 |
| TCMBANKGE000598 | MDK | ARAP; MK; NEGF2 | midkine |
| TCMBANKGE000599 | H3P23 | p27 | H3 histone pseudogene 23 |
| TCMBANKGE000600 | IFI27 | FAM14D; ISG12; ISG12A; P27 | interferon alpha inducible protein 27 |
| TCMBANKGE000601 | DCTN6 | WS-3; WS3; p27 | dynactin subunit 6 |
| TCMBANKGE000602 | HAND1 | Hxt; Thing1; bHLHa27; eHand | heart and neural crest derivatives expressed 1 |
| TCMBANKGE000603 | NELFCD | HSPC130; NELF-C; NELF-D; TH1; TH1L | negative elongation factor complex member C/D |
| TCMBANKGE000628 | CTSS | - | cathepsin S |
| TCMBANKGE000687 | POLDIP2 | PDIP38; POLD4; p38 | DNA polymerase delta interacting protein 2 |
| TCMBANKGE000688 | AIMP2 | HLD17; JTV-1; JTV1; P38 | aminoacyl tRNA synthetase complex interacting multifunctional protein 2 |
| TCMBANKGE000689 | GRAP2 | GADS; GRAP-2; GRB2L; GRBLG; GRID; GRPL; GrbX; Grf40; Mona; P38 | GRB2 related adaptor protein 2 |
| TCMBANKGE000690 | SYP | MRX96; MRXSYP | synaptophysin |
| TCMBANKGE000718 | H3P16 | H3F3AP6; p21 | H3 histone pseudogene 16 |
| TCMBANKGE000825 | CDKN1B | CDKN4; KIP1; MEN1B; MEN4; P27KIP1 | cyclin dependent kinase inhibitor 1B |
| TCMBANKGE000856 | CRK | CRKII; p38 | CRK proto-oncogene, adaptor protein |
| TCMBANKGE000857 | AHSA1 | AHA1; C14orf3; hAha1; p38 | activator of HSP90 ATPase activity 1 |
| TCMBANKGE000875 | ATF4 | CREB-2; CREB2; TAXREB67; TXREB | activating transcription factor 4 |
| TCMBANKGE001039 | PINK1 | BRPK; PARK6 | PTEN induced kinase 1 |
| TCMBANKGE001045 | CCND1 | BCL1; D11S287E; PRAD1; U21B31 | cyclin D1 |
| TCMBANKGE001051 | MAP2K7 | JNKK2; MAPKK7; MEK; MEK 7; MKK7; PRKMK7; SAPKK-4; SAPKK4 | mitogen-activated protein kinase kinase 7 |
| TCMBANKGE001073 | PTGS2 | COX-2; COX2; GRIPGHS; PGG/HS; PGHS-2; PHS-2; hCox-2 | prostaglandin-endoperoxide synthase 2 |
| TCMBANKGE001085 | MAPK8 | JNK; JNK-46; JNK1; JNK1A2; JNK21B1/2; PRKM8; SAPK1; SAPK1c | mitogen-activated protein kinase 8 |
| TCMBANKGE001096 | TLR4 | ARMD10; CD284; TLR-4; TOLL | toll like receptor 4 |
| TCMBANKGE001106 | MTOR | FRAP; FRAP1; FRAP2; RAFT1; RAPT1; SKS | mechanistic target of rapamycin kinase |
| TCMBANKGE001112 | PRKAB1 | AMPK; HAMPKb | protein kinase AMP-activated non-catalytic subunit beta 1 |
| TCMBANKGE001127 | PRKAA1 | AMPK; AMPKa1 | protein kinase AMP-activated catalytic subunit alpha 1 |
| TCMBANKGE001128 | PRKAA2 | AMPK; AMPK2; AMPKa2; PRKAA | protein kinase AMP-activated catalytic subunit alpha 2 |
| TCMBANKGE001144 | CD14 | - | CD14 molecule |
| TCMBANKGE001150 | EIF2S1 | EIF-2; EIF-2A; EIF-2alpha; EIF2; EIF2A | eukaryotic translation initiation factor 2 subunit alpha |
| TCMBANKGE001153 | EPHB2 | BDPLT22; CAPB; DRT; EK5; EPHT3; ERK; Hek5; PCBC; Tyro5 | EPH receptor B2 |
| TCMBANKGE001162 | IFNG | IFG; IFI | interferon gamma |
| TCMBANKGE001177 | TP53 | BCC7; BMFS5; LFS1; P53; TRP53 | tumor protein p53 |
| TCMBANKGE001201 | MAPK3 | ERK-1; ERK1; ERT2; HS44KDAP; HUMKER1A; P44ERK1; P44MAPK; PRKM3; p44-ERK1; p44-MAPK | mitogen-activated protein kinase 3 |
| TCMBANKGE001202 | MAPK14 | CSBP; CSBP1; CSBP2; CSPB1; EXIP; Mxi2; PRKM14; PRKM15; RK; SAPK2A; p38; p38ALPHA | mitogen-activated protein kinase 14 |
| TCMBANKGE001203 | MAPK1 | ERK; ERK-2; ERK2; ERT1; MAPK2; P42MAPK; PRKM1; PRKM2; p38; p40; p41; p41mapk; p42-MAPK | mitogen-activated protein kinase 1 |
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