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疾病ID:TCMBANKDI000069

疾病名:Bone neoplasms

MeSH_Name:Neoplasms; Musculoskeletal Diseases

HPO_Name:Neoplasm; Abnormality of the skeletal system

UMLS_Name:Neoplastic Process

DO_Name:disease of anatomical entity; disease of cellular proliferation

疾病类型:group

DisGeNET_Link:C0005967

MeSH_Link:C04; C05

HPO_Link:HP:0002664; HP:0000924

UMLS_Link:T191

DO_Link:DOID:7; DOID:14566

HERB_ID:HBDIS000372

   疾病对应的植物
ID 拉丁名 药名 药用植物名 功能与主治 来源 药用部位 使用民族
TCMBANKHE003739 Solanum nigrum L. 龙葵 Clove sore, swollen welling abscess, erysipelas, sprain from knocks and falls, mastitis, cervicitis, chronic bronchitis, chronic trachitis, acute nephritis, dysentery, infection of skin, leukorrhea, scant urine in children. aerial parts
   疾病对应的化合物
化合物ID 化合物名 别名 分子式 分子质量 Smiles
TCMBANKIN036848 triptolide PG 490; CT0223; Bio2_000315; AKOS015895128; KBio2_005451; BSPBio_001595; NCGC00163411-02; Triptolide; BCPP000033; Trisoxireno[4b,5:6,7:8a,9]phenanthro[1,2-c]furan-(3H)-one, 3b,4,4a,6,6a,7a,7b,8b,9,10-decahydro-6-hydroxy-8b-methyl-6a-(1-methylethyl)-, [3bR-(3b.alpha.,4a.alpha.,5aS*,6.beta.,6a.beta.,7a.beta.,7b.alpha.,8aS*,8b.beta.)]-; KBio3_000629; N1733; CHEBI:94966; SCHEMBL10028421; Trisoxireno(4b,5:6,7:8a,9)phenanthro(1,2-c)furan-1(3H)-one, 3b,4,4a,6,6a,7a,7b,8b,9,10-decahydro-6-hydroxy-8b-methyl-6a-(1-methylethyl)-, (3bS,4aS,5aS,6R,6aR,7aS,7bS,8aS,8bS)-; AC-6084; IDI1_034065; NCGC00163411-01; NSC163062; KBio2_002883; NSC 163062; Bio2_000795; Triptolid; HY-32735; BRD-A13122391-001-01-9; SMR000466307; MLS000759410; Triptolide (9CI); C09204; Triptolide, <i>Tripterygium wilfordii; PG-490; ST51052768; KBio2_000315; Trisoxireno[4b,5:6,7:8a,9]phenanthro[1,2-c]furan-1(3H)-one, 3b,4,4a,6,6a,7a,7b,8b,9,10-decahydro-6-hydroxy-8b-methyl-6a-(1-methylethyl)-, [3bR-(3b.alpha.,4a.alpha.,5aS*,6.beta.,6a.beta.,7a.beta.,7b.alpha.,8aS*,8b.beta.)]-; CS-0286; KBio3_000630; Triptolide, from Tripterygium wilfordii, >=98% (HPLC), solid; 38748-32-2; PG490; SMP1_000110; KBioGR_000315; TPL; NCI60_001223; KBioSS_000315 C20H24O6 360.4 CC(C)C12C(O1)C3C4(O3)C5(CCC6=C(C5CC7C4(C2O)O7)COC6=O)C
   疾病对应的靶点
靶点ID 基因名 基因别名 描述
TCMBANKGE010371 PTRH1 C9orf115; PTH1 peptidyl-tRNA hydrolase 1 homolog
TCMBANKGE001811 PTHLH BDE2; HHM; PLP; PTHR; PTHRP parathyroid hormone like hormone
TCMBANKGE001079 CYP1A1 AHH; AHRR; CP11; CYP1; CYPIA1; P1-450; P450-C; P450DX cytochrome P450 family 1 subfamily A member 1
TCMBANKGE000070 CAV1 BSCL3; CGL3; LCCNS; MSTP085; PPH3; VIP21 caveolin 1
TCMBANKGE000117 RUNX3 AML2; CBFA3; PEBP2aC RUNX family transcription factor 3
TCMBANKGE005047 GHRH GHRF; GRF; INN growth hormone releasing hormone
TCMBANKGE000453 NR1I3 CAR; CAR1; MB67 nuclear receptor subfamily 1 group I member 3
TCMBANKGE005344 QPCT GCT; QC; sQC glutaminyl-peptide cyclotransferase
TCMBANKGE000137 PLAU ATF; BDPLT5; QPD; UPA; URK; u-PA plasminogen activator, urokinase
TCMBANKGE011934 LYST CHS; CHS1 lysosomal trafficking regulator
TCMBANKGE001197 FOS AP-1; C-FOS; p55 Fos proto-oncogene, AP-1 transcription factor subunit
TCMBANKGE001002 SYT1 BAGOS; P65; SVP65; SYT synaptotagmin 1
TCMBANKGE000626 ATRNL1 ALP; bA338L11.1; bA454H24.1 attractin like 1
TCMBANKGE000567 CDKN2A ARF; CDK4I; CDKN2; CMM2; INK4; INK4A; MLM; MTS-1; MTS1; P14; P14ARF; P16; P16-INK4A; P16INK4; P16INK4A; P19; P19ARF; TP16 cyclin dependent kinase inhibitor 2A
TCMBANKGE006388 EBF3 COE3; EBF-3; HADDS; O/E-2; OE-2 EBF transcription factor 3
TCMBANKGE000970 FASN FAS; OA-519; SDR27X1 fatty acid synthase
TCMBANKGE003498 BTG4 APRO3; PC3B BTG anti-proliferation factor 4
TCMBANKGE008865 FOLH1 FGCP; FOLH; GCP2; GCPII; NAALAD1; NAALAdase; PSM; PSMA; mGCP folate hydrolase 1
TCMBANKGE008151 SPARC BM-40; OI17; ON; ONT secreted protein acidic and cysteine rich
TCMBANKGE001103 MDM2 ACTFS; HDMX; LSKB; hdm2 MDM2 proto-oncogene
TCMBANKGE014985 PTH FIH1; PTH1 parathyroid hormone
TCMBANKGE013604 PLOD2 BRKS2; LH2; TLH procollagen-lysine,2-oxoglutarate 5-dioxygenase 2
TCMBANKGE000625 NAT10 ALP; Kre33; NET43 N-acetyltransferase 10
TCMBANKGE000135 CXCR4 CD184; D2S201E; FB22; HM89; HSY3RR; LAP-3; LAP3; LCR1; LESTR; NPY3R; NPYR; NPYRL; NPYY3R; WHIM; WHIMS C-X-C motif chemokine receptor 4
TCMBANKGE000464 TRIM13 CAR; DLEU5; LEU5; RFP2; RNF77 tripartite motif containing 13
TCMBANKGE011026 TCF7 TCF-1 transcription factor 7
TCMBANKGE000066 YY1 DELTA; GADEVS; INO80S; NF-E1; UCRBP; YIN-YANG-1 YY1 transcription factor
TCMBANKGE000047 AKT1 AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA AKT serine/threonine kinase 1
TCMBANKGE000680 CTSK CTS02; CTSO; CTSO1; CTSO2; PKND; PYCD cathepsin K
TCMBANKGE000620 ATHS ALP atherosclerosis susceptibility (lipoprotein associated)
TCMBANKGE003444 EWSR1 EWS; EWS-FLI1; bK984G1.4 EWS RNA binding protein 1
TCMBANKGE010653 FLI1 BDPLT21; EWSR2; SIC-1 Fli-1 proto-oncogene, ETS transcription factor
TCMBANKGE000864 FHL2 AAG11; DRAL; FHL-2; SLIM-3; SLIM3 four and a half LIM domains 2
TCMBANKGE000568 MET AUTS9; DFNB97; HGFR; RCCP2; c-Met MET proto-oncogene, receptor tyrosine kinase
TCMBANKGE000967 BIRC7 KIAP; LIVIN; ML-IAP; MLIAP; RNF50 baculoviral IAP repeat containing 7
TCMBANKGE009334 SDC2 CD362; HSPG; HSPG1; SYND2 syndecan 2
TCMBANKGE001048 TGM2 TG(C); TGC transglutaminase 2
TCMBANKGE000201 ESR1 ER; ESR; ESRA; ESTRR; Era; NR3A1 estrogen receptor 1
TCMBANKGE001038 SERPINF1 EPC-1; OI12; OI6; PEDF; PIG35 serpin family F member 1
TCMBANKGE000457 CXADR CAR; CAR4/6; HCAR CXADR Ig-like cell adhesion molecule
TCMBANKGE000986 ERBB2 CD340; HER-2; HER-2/neu; HER2; MLN 19; NEU; NGL; TKR1 erb-b2 receptor tyrosine kinase 2
TCMBANKGE014353 ERBB3 ErbB-3; FERLK; HER3; LCCS2; MDA-BF-1; c-erbB-3; c-erbB3; erbB3-S; p180-ErbB3; p45-sErbB3; p85-sErbB3 erb-b2 receptor tyrosine kinase 3
TCMBANKGE001437 NME1 AWD; GAAD; NB; NBS; NDKA; NDPK-A; NDPKA; NM23; NM23-H1 NME/NM23 nucleoside diphosphate kinase 1
TCMBANKGE003580 PDXP CIN; PLP; dJ37E16.5 pyridoxal phosphatase
TCMBANKGE000929 MIR145 MIRN145; miR-145; miRNA145 microRNA 145
TCMBANKGE000462 ARR3 ARRX; MYP26; cArr arrestin 3
TCMBANKGE001037 MMP2 CLG4; CLG4A; MMP-2; MMP-II; MONA; TBE-1 matrix metallopeptidase 2
TCMBANKGE000627 BGLAP BGP; OC; OCN bone gamma-carboxyglutamate protein
TCMBANKGE000270 KHDRBS1 Sam68; p62; p68 KH RNA binding domain containing, signal transduction associated 1
TCMBANKGE008121 CDH13 CDHH; P105 cadherin 13
TCMBANKGE009726 ERG erg-3; p55 ETS transcription factor ERG
TCMBANKGE000976 TNFSF11 CD254; ODF; OPGL; OPTB2; RANKL; TNLG6B; TRANCE; hRANKL2; sOdf TNF superfamily member 11
TCMBANKGE000619 ASRGL1 ALP; ALP1; CRASH asparaginase and isoaspartyl peptidase 1
TCMBANKGE000199 ICAM1 BB2; CD54; P3.58 intercellular adhesion molecule 1
TCMBANKGE000202 RUNX2 AML3; CBF-alpha-1; CBFA1; CCD; CCD1; CLCD; OSF-2; OSF2; PEA2aA; PEBP2aA RUNX family transcription factor 2
TCMBANKGE001097 HIF1A HIF-1-alpha; HIF-1A; HIF-1alpha; HIF1; HIF1-ALPHA; MOP1; PASD8; bHLHe78 hypoxia inducible factor 1 subunit alpha
TCMBANKGE012029 TSPAN31 SAS tetraspanin 31
TCMBANKGE015151 HPGDS GSTS; GSTS1; GSTS1-1; PGD2; PGDS hematopoietic prostaglandin D synthase
TCMBANKGE000346 RPS6KA3 CLS; HU-3; ISPK-1; MAPKAPK1B; MRX19; RSK; RSK2; S6K-alpha3; p90-RSK2; pp90RSK2 ribosomal protein S6 kinase A3
TCMBANKGE009559 CD99 HBA71; MIC2; MIC2X; MIC2Y; MSK5X CD99 molecule (Xg blood group)
TCMBANKGE000001 CXCR2 CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB C-X-C motif chemokine receptor 2
TCMBANKGE014448 FGF23 ADHR; FGFN; HFTC2; HPDR2; HYPF; PHPTC fibroblast growth factor 23
TCMBANKGE011010 RUNX1 AML1; AML1-EVI-1; AMLCR1; CBF2alpha; CBFA2; EVI-1; PEBP2aB; PEBP2alpha RUNX family transcription factor 1
TCMBANKGE000280 VIM - vimentin
TCMBANKGE001073 PTGS2 COX-2; COX2; GRIPGHS; PGG/HS; PGHS-2; PHS-2; hCox-2 prostaglandin-endoperoxide synthase 2
TCMBANKGE001030 NOTCH1 AOS5; AOVD1; TAN1; hN1 notch receptor 1
TCMBANKGE014548 FGF9 FGF-9; GAF; HBFG-9; HBGF-9; SYNS3 fibroblast growth factor 9
TCMBANKGE002600 FUS ALS6; ETM4; FUS1; HNRNPP2; POMP75; TLS FUS RNA binding protein
TCMBANKGE011129 GH1 GH; GH-N; GHB5; GHN; IGHD1A; IGHD1B; IGHD2; hGH-N growth hormone 1
TCMBANKGE002159 PDPN AGGRUS; GP36; GP40; Gp38; HT1A-1; OTS8; PA2.26; T1A; T1A-2; T1A2; TI1A podoplanin
TCMBANKGE000482 IDH1 HEL-216; HEL-S-26; IDCD; IDH; IDP; IDPC; PICD isocitrate dehydrogenase (NADP(+)) 1
TCMBANKGE000681 TNFRSF11B OCIF; OPG; PDB5; TR1 TNF receptor superfamily member 11b
TCMBANKGE001065 KLF4 EZF; GKLF Kruppel like factor 4
TCMBANKGE006172 EXT2 SOTV; SSMS exostosin glycosyltransferase 2
TCMBANKGE010789 HNF1A HNF-1A; HNF1; HNF4A; IDDM20; LFB1; MODY3; TCF-1; TCF1 HNF1 homeobox A
TCMBANKGE013033 NANS HEL-S-100; SAS; SEMDCG; SEMDG N-acetylneuraminate synthase
TCMBANKGE000465 CASR CAR; EIG8; FHH; FIH; GPRC2A; HHC; HHC1; HYPOC1; NSHPT; PCAR1; hCasR calcium sensing receptor
TCMBANKGE000310 FOSB AP-1; G0S3; GOS3; GOSB FosB proto-oncogene, AP-1 transcription factor subunit
TCMBANKGE012118 TMPRSS2 PRSS10 transmembrane serine protease 2
TCMBANKGE011054 KCNIP4 CALP; KCHIP4 potassium voltage-gated channel interacting protein 4
TCMBANKGE000109 ACTB BRWS1; PS1TP5BP1 actin beta
TCMBANKGE001170 CDK4 CMM3; PSK-J3 cyclin dependent kinase 4
TCMBANKGE001109 ALPP ALP; ALPI; IAP; PALP; PLAP; PLAP-1 alkaline phosphatase, placental
TCMBANKGE001011 TNFSF10 APO2L; Apo-2L; CD253; TL2; TNLG6A; TRAIL TNF superfamily member 10
TCMBANKGE000622 SLPI ALK1; ALP; BLPI; HUSI; HUSI-I; MPI; WAP4; WFDC4 secretory leukocyte peptidase inhibitor
TCMBANKGE000795 POU5F1 OCT3; OCT4; OTF-3; OTF3; OTF4; Oct-3; Oct-4 POU class 5 homeobox 1
TCMBANKGE009400 GNAS AHO; C20orf45; GNAS1; GPSA; GSA; GSP; NESP; PITA3; POH; SCG6; SgVI GNAS complex locus
TCMBANKGE000400 CSK - C-terminal Src kinase
TCMBANKGE002000 CTLA4 ALPS5; CD; CD152; CELIAC3; CTLA-4; GRD4; GSE; IDDM12 cytotoxic T-lymphocyte associated protein 4
TCMBANKGE010090 NFATC2 NFAT1; NFATP nuclear factor of activated T cells 2
TCMBANKGE001686 CTSL CATL; CTSL1; MEP cathepsin L
TCMBANKGE000891 ABCC3 ABC31; EST90757; MLP2; MOAT-D; MRP3; cMOAT2 ATP binding cassette subfamily C member 3
TCMBANKGE000679 BTF3P11 BTF3L1; HUMBTFB; OCIF; OPG; TNFRSF11B basic transcription factor 3 pseudogene 11
TCMBANKGE007130 BCOR ANOP2; MAA2; MCOPS2 BCL6 corepressor
TCMBANKGE000361 ERCC2 COFS2; EM9; TFIIH; TTD; TTD1; XPD ERCC excision repair 2, TFIIH core complex helicase subunit
TCMBANKGE005826 MUC16 CA125 mucin 16, cell surface associated
TCMBANKGE004738 PEG10 EDR; HB-1; MEF3L; Mar2; Mart2; RGAG3; RTL2; SIRH1 paternally expressed 10
TCMBANKGE008602 KLF6 BCD1; CBA1; COPEB; CPBP; GBF; PAC1; ST12; ZF9 Kruppel like factor 6
TCMBANKGE000340 ACP5 HPAP; TRACP5a; TRACP5b; TRAP; TrATPase acid phosphatase 5, tartrate resistant
TCMBANKGE000264 ABCB1 ABC20; CD243; CLCS; GP170; MDR1; P-GP; PGY1 ATP binding cassette subfamily B member 1
TCMBANKGE000885 SPP1 BNSP; BSPI; ETA-1; OPN secreted phosphoprotein 1
TCMBANKGE013971 ANXA3 ANX3 annexin A3
TCMBANKGE009089 EXT1 EXT; LGCR; LGS; TRPS2; TTV exostosin glycosyltransferase 1
TCMBANKGE001108 BMP2 BDA2; BMP2A; SSFSC bone morphogenetic protein 2
TCMBANKGE000621 PDLIM3 ALP PDZ and LIM domain 3
TCMBANKGE000468 CTSB APPS; CPSB; RECEUP cathepsin B
TCMBANKGE008183 ACE ACE1; CD143; DCP; DCP1 angiotensin I converting enzyme
TCMBANKGE000339 TNFRSF11A CD265; FEO; LOH18CR1; ODFR; OFE; OPTB7; OSTS; PDB2; RANK; TRANCER TNF receptor superfamily member 11a
TCMBANKGE000623 CCL27 ALP; CTACK; CTAK; ESKINE; ILC; PESKY; SCYA27 C-C motif chemokine ligand 27
TCMBANKGE002395 HLA-DOA HLA-DNA; HLA-DZA; HLADZ major histocompatibility complex, class II, DO alpha
TCMBANKGE000456 CXADRP1 CAR; CXADRP CXADR pseudogene 1
TCMBANKGE004329 FGF1 AFGF; ECGF; ECGF-beta; ECGFA; ECGFB; FGF-1; FGF-alpha; FGFA; GLIO703; HBGF-1; HBGF1 fibroblast growth factor 1
TCMBANKGE012224 VDR NR1I1; PPP1R163 vitamin D receptor
TCMBANKGE004203 TGFBR2 AAT3; FAA3; LDS1B; LDS2; LDS2B; MFS2; RIIC; TAAD2; TBR-ii; TBRII; TGFR-2; TGFbeta-RII transforming growth factor beta receptor 2
TCMBANKGE007692 GSTM1 GST1; GSTM1-1; GSTM1a-1a; GSTM1b-1b; GTH4; GTM1; H-B; MU; MU-1 glutathione S-transferase mu 1
TCMBANKGE014757 IDH2 D2HGA2; ICD-M; IDH; IDHM; IDP; IDPM; mNADP-IDH isocitrate dehydrogenase (NADP(+)) 2
TCMBANKGE000459 PRKAR1A ACRDYS1; ADOHR; CAR; CNC; CNC1; PKR1; PPNAD1; PRKAR1; TSE1 protein kinase cAMP-dependent type I regulatory subunit alpha
TCMBANKGE002526 BAP1 HUCEP-13; UCHL2; hucep-6 BRCA1 associated protein 1
TCMBANKGE000463 SPG7 CAR; CMAR; PGN; SPG5C SPG7 matrix AAA peptidase subunit, paraplegin
TCMBANKGE000639 HRAS C-BAS/HAS; C-H-RAS; C-HA-RAS1; CTLO; H-RASIDX; HAMSV; HRAS1; RASH1; p21ras HRas proto-oncogene, GTPase
TCMBANKGE012142 GDE1 363E6.2; MIR16 glycerophosphodiester phosphodiesterase 1
TCMBANKGE000712 COL1A1 CAFYD; EDSARTH1; EDSC; OI1; OI2; OI3; OI4 collagen type I alpha 1 chain
TCMBANKGE000475 NCOA3 ACTR; AIB-1; AIB1; CAGH16; CTG26; KAT13B; RAC3; SRC-3; SRC3; TNRC14; TNRC16; TRAM-1; bHLHe42; pCIP nuclear receptor coactivator 3

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