Compound Summary


  Compound Information

药名:

salidroside

别名:

10338-51-9; (2R,3S,4S,5R,6R)-2-(hydroxymethyl)-6-[2-(4-hydroxyphenyl)ethoxy]oxane-3,4,5-triol; SCHEMBL17580247; (2R,3R,4S,5S,6R)-2-[2-(4-hydroxyphenyl)ethoxy]-6-methylol-tetrahydropyran-3,4,5-triol; ACon1_000366; 2-(4-Hydroxyphenyl)ethyl beta-D-glucopyranoside; Glucopyranoside, p-hydroxyphenethyl; Rhodosin; (2R,3S,4S,5R,6R)-2-(hydroxymethyl)-6-[2-(4-hydroxyphenyl)ethoxy]tetrahydropyran-3,4,5-triol; MEGxp0_000478; Rhodioloside; beta-D-Glucopyranoside, 2-(4-hydroxyphenyl)ethyl;

分子式:

C14H20O7

Smiles:

C1=CC(=CC=C1CCOC2C(C(C(C(O2)CO)O)O)O)O

成分:

HBIN042854;HBIN042249;HBIN042279

OB_score:

7.010258

CAS_id:

10338-51-9

SymMap_id:

SMIT00172;SMIT17462

TCMID_id:

23020;18777

TCMSP_id:

MOL002929;MOL003341

PubChem_id:

159278


   化合物对应的植物
植物ID 拉丁名 药用植物名 药名 来源 功能与主治 使用民族
TCMBANKHE000451 Radix Semiaquilegiae 天葵子 To remove toxic heat and promote the subsidence of swelling./Treatment of carbuncles, boils and sores, mastitis, scrofula, venomous snake bite.
TCMBANKHE000850 Radix Rehmanniae 生地黄 Treatment of exogenous heat invading at the nutritive and blood levels manifested as dry mouth and deep red tongue proper with scanty coating. Fresh rehmannia root (Shengdihuang) is used with Scrophularia (Xuanshen), Rhinoceros horn (Xijiao) and Ophiopogon root/1. Its decoction exerts a protective effect on experimental hepatitis of mice induced by carbon tetrachloride.2. Gastric feeding or injection of its decoction, water infusion or alcoholic extract can lower the blood sugar level in rabbits (this result is controversial in the recent years).3. Intravenous injection of its extract exerts a hypertensive and diuretic effect in rabbits and dogs.4. Its alcoholic extract shortens the blood coagulation time in rabbits.5. Its water infusion inhibits the growth of some pathogenic fungi.
TCMBANKHE000910 Rhodiola algida 吉氏红景天
TCMBANKHE001675 景天三七
TCMBANKHE002292 橘红
TCMBANKHE002552 零陵香
TCMBANKHE003746 Radix Scutellariae 黄芩 To remove damp-heat, to quench fire and counteract toxicity, to arrest bleeding, and to prevent abortion./Chest oppression with retching, diarrhea, jaundice, lung heat cough, infection of upper respiratory tract, acute tonsillitis, acute pharyngolaryngitis, ardent fever with vexation and thirst, blood heat, blood ejection, spontaneous external bleeding, swelling toxin of welling abscess and sore, stirring fetus in pregnancy.
TCMBANKHE003799 Fructus Forsythiae 连翘 To remove toxic heat, to cause subsidence of sweeling,and to eliminate modulation./Influenza in early stage, common cold in early stage, wind-heat common cold, encephalitis, hepatitis, tuberculosis, warm disease, heat strangury with inhibited pain, welling abscess, welling abscess and flat abscess, toxin swelling, scrofula, goiter and tuberculosis, throat impediment.
TCMBANKHE003834 草苁蓉 Kidney vacuity impotence, emission, cold pain in lumbus and knees, dribbling urination, hematuria, infertility due to uterus cold, vaginal discharge, flooding and spotting, intestinal dry and constipation.
TCMBANKHE003857 Semen Strychni 马钱子 To promote the flow of qi and blood in the collaterals, relieve pain, and promote the subsidence of swelling./Hemiplegia, numbness and paralysis, muscle weakness, impotence, hypertrophic spinitis, chronic anemia, wind-damp intractable impediment, sequel of poliomyelitis, rheumatoid arthritis, knocks and falls, swelling pain of welling abscess and flat abscess.
TCMBANKHE004431 Semen Strychni;Strychnos dolichothyrsa;Semen Cumini Cymni;Strychnos mittschelichii 马钱子 To promote the flow of qi and blood in the collaterals, relieve pain, and promote the subsidence of swelling./Hemiplegia, numbness and paralysis, muscle weakness, impotence, hypertrophic spinitis, chronic anemia, wind-damp intractable impediment, sequel of poliomyelitis, rheumatoid arthritis, knocks and falls, swelling pain of welling abscess and flat abscess.
TCMBANKHE006166 Vaccinium vitis-idaea 越橘叶 To disinhibit urine, resolve toxin./Strangury syndrome, pain wind.
TCMBANKHE004461 Phillyrea latifolia 阔叶欧女贞 To promote contraction, disinhibit urine. [5509]/Headache. [5509]
TCMBANKHE004497 Semen Raphani 莱菔子 To promote digestion and relieve abdominal distension, and to relieve cough and resolve phlegm./Food stagnation, distending pain in stomach duct, constipation, accumulation and diarrhea, phlegm congestion cough asthma.
TCMBANKHE004568 Rhodiola crenulata [Syn. Rhodiola euryphylla] 大花红景天 To clear lung and boost qi./Tuberculosis with cough, hemoptysis, pneumonia, b ronchitis.
TCMBANKHE004616 地黄
TCMBANKHE006658 Rhodiola yunnanesis 云南红景天 To supplement lung and boost kidney, clear heat and relieve cough, dissipate stasis and stanch bleeding./Vacuity taxation with cough, kidney vacuity lumbar pain, pain in throat, painful swelling from knocks and falls, bleeding due to external injury.
TCMBANKHE005090 Caulis Sargentodoxae 大血藤 To remove toxic heat, to promote blood circulation, and to relieve rheumatic conditions./Intestinal welling abscess and abdominal pain, amenorrhea, dysmenorrhea, wind-damp impediment pain, painful swelling from knocks and falls.
TCMBANKHE005158 淫羊藿 Angina pectoris, chronic bronchitis, neurasthenia, climacteric hypertension, poliomyelitis, impotence and emission, limp wilting sinew and bone, wind-damp impediment pain, hypertonicity and numbness.
TCMBANKHE005339 Rhodiola coccinea 深红红景天
TCMBANKHE007786 Rhodiola himalansis 喜马红景天;西马鸿景天
TCMBANKHE006038 Rhodiola subopposita 互生红景天
TCMBANKHE006428 Herba Cistanches 肉苁蓉 To reinforce the kidney, replenish vital essence and blood, and induce Taxation./Impotence, infertility, backache, limp aching lumbus and knees, weakness in sinews and bones, intestinal dry and constipation.
TCMBANKHE008551 Rhodiola quadrifida 四裂红景天;撕裂红景天 To boost kidney and nourish liver, regulate menstruation and quicken blood./Steaming bone taxation fever, dry blood tisis (consumptive disease due to blood disorders), dizzy head and vision, menstrual disorder [=menoxenia].
TCMBANKHE006912 Rhodiola juparensis 圆丛红景天
TCMBANKHE008143 Radix et Rhizoma Rhodiolae 红景天 For tonifying qi
TCMBANKHE008359 Semen Oroxyli 木蝴蝶 To remove heat from the lung and relieve sore throat, and to regulate the flow of qi of the liver and the stomach./Lung heat cough, throat impediment, aphonia, liver stomach qi pain.
TCMBANKHE009021 Rhodiola sacra 圣地红景天 To supplement qi and clear lung, boost wits and nourish heart, promote contraction and stanch bleeding, dissipate stasis and disperse swelling./Qi vacuity and general weakness, aversion of cold during convalescence, shortness of breath and hypodynamia, lung heat cough, hemoptysis, leukorrhea, diarrhea, knocks and falls, burns and scalds, neurosis, altitude stress.
TCMBANKHE008951 Rhodiola kirilowii 狭叶红景天 To nourish heart and quiet spirit, quicken blood and transform stasis, stanch bleeding, clear heat and resolve toxin./Qi vacuity and general weakness, shortness of breath and hypodynamia, palpitation and insomnia, dizziness, chest oppression and pain, knocks and falls, menstrual disorder, flooding and spotting, blood ejection, dysentery, diarrhea.
TCMBANKHE004023/YEM-391/XU-797 Fructus Ligustri lucidi|Ligustrum lucidum Ait.|Ligustrum lucidum 女贞子|女贞 女贞子 云南民族药物志:第二卷|云南省文山州麻栗坡县 To replenish the liver and kidney, improve eyesight and promote the growth of black hair.;Treament of vertigo, tinnitus, weakness in the loins and knees, premature whitening of hair and impaired eyesight due to deficiency of yin of the liver and kidney./Septicemia, chronic bronchitis, acute dysentery, dizziness and tinnitus, premature graying in beard and hair, dim vision.;1. Its component oleanolic acid can prevent and relieve cyclophosphamide-induced leukocytopenia in mice.2. Enhancing the anoxia tolerance of mice under atmospheric pressure.3. Increasing coronary flow in rabbits in vitro.4. Relaxing adrenaline-induced vasocontricyion in rabbits in vitro.5. Lowering the level of blood lipid. 阿昌族/德昂族/基诺族/景颇族/傈僳族/水族
TCMBANKHE005333/YEM-568 Fagopyrum esculentum|Fagopyrum esculentum Moench 荞麦 甜荞 云南民族药物志:第三卷 To fortify spleen and disperse accumulation, precipitate qi and loosen intestines, resolve toxin and close sores./Gastrointestinal accumulation, diarrhea, dysentery, intestine gripping sand, white turbidity, vaginal discharge, spontaneous sweating, night sweating, zoster, erysipelas, effusion of back from welling abscess and flat abscess, scrofula, burns and scalds. 哈尼族/佤族/彝族
TCMBANKHE006111/YEM-858 Lamiophlomis rotata [Syn. Phlomis rotata ]|Lamiophlomis rotata(Benth.)Kudo 独一味 独一味 云南民族药物志:第五卷 To quicken blood and transform stasis, disperse swelling and relieve pain./Knocks and falls, pain in sinews and bones, swelling pain in joints, dysmenorrhea, flooding and spotting. 阿昌族/傣族/德昂族/景颇族/傈僳族/纳西族/普米族/藏族
TCMBANKHE006600/YEM-970/XU-590 Carduus crispus|Carduus acanthoides L.|Carduus acanthoides 飞廉|节毛飞廉 红马刺 云南民族药物志:第五卷|甘肃省定西市岷县 To dispel wind, clear heat, disinhibit damp, cool blood and stanch bleeding, quicken blood and disperse swelling./Common cold with cough, headache and dizziness, infection of urinary system, chyluria, vaginal discharge, jaundice, wind-heat impediment pain, blood ejection, spontaneous external bleeding, hematuria, profuse menstruation, dysfunctional uterine bleeding, knocks and falls, clove sore and swollen boil, toxin swelling from hemorrhoids, scalds. 藏族

   植物对应的疾病
疾病ID 病名 疾病类型 MeSH 参考文献
TCMBANKDI000031 Insulin Resistance phenotype Nutritional and Metabolic Diseases 25754463
TCMBANKDI000054 Alzheimer's Disease disease Nervous System Diseases; Mental Disorders 27933142
TCMBANKDI000081 Diabetes Mellitus, Experimental disease Nutritional and Metabolic Diseases; Endocrine System Diseases 30624028
TCMBANKDI000096 Hyperglycemia disease Nutritional and Metabolic Diseases 30624028
TCMBANKDI005544 Diabetic Retinopathy disease Eye Diseases; Endocrine System Diseases; Cardiovascular Diseases 31251107
TCMBANKDI013917 Pulmonary Hypertension phenotype Respiratory Tract Diseases 25772255
TCMBANKDI015496 Liver neoplasms group Digestive System Diseases; Neoplasms 30396856
TCMBANKDI018458 Intervertebral Disc Degeneration disease Musculoskeletal Diseases 30250268
TCMBANKDI023555 Hypoxia phenotype Pathological Conditions, Signs and Symptoms 30396856
TCMBANKDI028126 Vascular Remodeling phenotype Pathological Conditions, Signs and Symptoms 25772255
TCMBANKDI030400 Cancer cachexia disease - 27493875
TCMBANKDI031985 Brain Ischemia disease Nervous System Diseases; Cardiovascular Diseases 29426336

   化合物对应的靶点
靶点ID 基因名 基因别名 描述
TCMBANKGE000013 G6PC G6PC1; G6PT; G6Pase; GSD1; GSD1a glucose-6-phosphatase catalytic subunit
TCMBANKGE000014 PCK1 PCKDC; PEPCK-C; PEPCK1; PEPCKC phosphoenolpyruvate carboxykinase 1
TCMBANKGE000015 ADORA2A A2aR; ADORA2; RDC8 adenosine A2a receptor
TCMBANKGE000016 MYH6 ASD3; CMD1EE; CMH14; MYHC; MYHCA; SSS3; alpha-MHC myosin heavy chain 6
TCMBANKGE000017 MAPT DDPAC; FTDP-17; MAPTL; MSTD; MTBT1; MTBT2; PPND; PPP1R103; TAU microtubule associated protein tau
TCMBANKGE000018 KAT2B CAF; P/CAF; PCAF lysine acetyltransferase 2B
TCMBANKGE000047 AKT1 AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA AKT serine/threonine kinase 1
TCMBANKGE000052 TNF DIF; TNF-alpha; TNFA; TNFSF2; TNLG1F tumor necrosis factor
TCMBANKGE000053 NFKB1 CVID12; EBP-1; KBF1; NF-kB; NF-kB1; NF-kappa-B1; NF-kappaB; NF-kappabeta; NFKB-p105; NFKB-p50; NFkappaB nuclear factor kappa B subunit 1
TCMBANKGE000251 FGF2 BFGF; FGF-2; FGFB; HBGF-2 fibroblast growth factor 2
TCMBANKGE000286 GSK3B - glycogen synthase kinase 3 beta
TCMBANKGE000305 PIK3CD APDS; IMD14; P110DELTA; PI3K; p110D phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
TCMBANKGE000306 PIK3CG PI3CG; PI3K; PI3Kgamma; PIK3; p110gamma; p120-PI3K phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma
TCMBANKGE000307 PIK3CB P110BETA; PI3K; PI3KBETA; PIK3C1 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
TCMBANKGE000308 PIK3CA CLAPO; CLOVE; CWS5; MCAP; MCM; MCMTC; PI3K; PI3K-alpha; p110-alpha phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
TCMBANKGE000330 HMOX1 HMOX1D; HO-1; HSP32; bK286B10 heme oxygenase 1
TCMBANKGE000568 MET AUTS9; DFNB97; HGFR; RCCP2; c-Met MET proto-oncogene, receptor tyrosine kinase
TCMBANKGE000817 PGAM5 BXLBV68 PGAM family member 5, mitochondrial serine/threonine protein phosphatase
TCMBANKGE000968 CYCS CYC; HCS; THC4 cytochrome c, somatic
TCMBANKGE000988 HGF DFNB39; F-TCF; HGFB; HPTA; SF hepatocyte growth factor
TCMBANKGE001089 PARP1 ADPRT; ADPRT 1; ADPRT1; ARTD1; PARP; PARP-1; PPOL; pADPRT-1 poly(ADP-ribose) polymerase 1
TCMBANKGE001097 HIF1A HIF-1-alpha; HIF-1A; HIF-1alpha; HIF1; HIF1-ALPHA; MOP1; PASD8; bHLHe78 hypoxia inducible factor 1 subunit alpha
TCMBANKGE001106 MTOR FRAP; FRAP1; FRAP2; RAFT1; RAPT1; SKS mechanistic target of rapamycin kinase
TCMBANKGE001112 PRKAB1 AMPK; HAMPKb protein kinase AMP-activated non-catalytic subunit beta 1
TCMBANKGE001114 IL6 BSF-2; BSF2; CDF; HGF; HSF; IFN-beta-2; IFNB2; IL-6 interleukin 6
TCMBANKGE001127 PRKAA1 AMPK; AMPKa1 protein kinase AMP-activated catalytic subunit alpha 1
TCMBANKGE001128 PRKAA2 AMPK; AMPK2; AMPKa2; PRKAA protein kinase AMP-activated catalytic subunit alpha 2
TCMBANKGE001131 CASP9 APAF-3; APAF3; ICE-LAP6; MCH6; PPP1R56 caspase 9
TCMBANKGE001132 BAX BCL2L4 BCL2 associated X, apoptosis regulator
TCMBANKGE001148 VEGFA MVCD1; VEGF; VPF vascular endothelial growth factor A
TCMBANKGE001166 BCL2 Bcl-2; PPP1R50 BCL2 apoptosis regulator
TCMBANKGE001169 BCL2L1 BCL-XL/S; BCL2L; BCLX; Bcl-X; PPP1R52 BCL2 like 1
TCMBANKGE001182 SIRT1 SIR2; SIR2L1; SIR2alpha sirtuin 1
TCMBANKGE001184 RELA CMCU; NFKB3; p65 RELA proto-oncogene, NF-kB subunit
TCMBANKGE001201 MAPK3 ERK-1; ERK1; ERT2; HS44KDAP; HUMKER1A; P44ERK1; P44MAPK; PRKM3; p44-ERK1; p44-MAPK mitogen-activated protein kinase 3
TCMBANKGE001203 MAPK1 ERK; ERK-2; ERK2; ERT1; MAPK2; P42MAPK; PRKM1; PRKM2; p38; p40; p41; p41mapk; p42-MAPK mitogen-activated protein kinase 1
TCMBANKGE001205 DDIT3 AltDDIT3; C/EBPzeta; CEBPZ; CHOP; CHOP-10; CHOP10; GADD153 DNA damage inducible transcript 3