Compound Summary


  Compound Information

药名:

Germacrene B

分子式:

C15H24

Smiles:

CC1=CCCC(=CCC(=C(C)C)CC1)C

成分:

HBIN027567; HBIN013801

OB_score:

18.691752; 18.555814

CAS_id:

15423-57-1

SymMap_id:

SMIT03429;SMIT15531; SMIT03170

TCMID_id:

8342;35532

TCMSP_id:

MOL000936; MOL000613

PubChem_id:

6370843


   化合物对应的植物
植物ID 拉丁名 药用植物名 药名 来源 功能与主治 使用民族
TCMBANKHE000214 Rhizoma Curcumae 莪术 To promote the flow of qi and eliminate blood stasis with strong effect, and to relieve pain by removing the stagnation of undigested food./1. Its volatile oil and its components curcumenol, curdione and B-elemene destroy directly the Ehrlich-Ascites tumor and leukemia615 in mice. 2. Promoting phagocytosis of monocytes. 3. Dilating peripheral blood vessels, inhibiting aggregation of thrombocytes and thrombosis, and improving microcirculation.
TCMBANKHE000786 苦楝子
TCMBANKHE002542 Fructus Schiandrae 北五味 Treatment of chronic cough and asthma, nocturnal emission, spermatorrhea, enuresis, frequent urination, protracted diarrhea, spontaneous sweating, night sweating, impairment of body fluid with thirst, shortness of breath and feeble pulse, diabetes caused by internal heat, palpitation and insomnia./1. Its decoction exerts bacteriostatic effect on Pseudomonas aeruginosa (1:128), Staphylococcus aureus (1:64), Flexner's bacillus (1:32) and typhoid bacillus (1:8) in vitro.2. Schizandrin, one of its active components, can protect the liver from damage.3. Enhancing lymphocyte-blastogenesis rate.4. Cardiotonic and sedative.
TCMBANKHE003222 Folium Viticis Negundo 牡荆叶 To counteract toxicity, and to induce expectoration, relieve cough and asthma./1. Oral administration of its eemulsion (0.52-1.73g.kg) exerts a strong expectorant effect in mice.2. Oral administration of its volatile oil (1.04g/kg) exerts a significant antitussive effect in mice with cough induced by inhalation of concentrated ammonia.3. Increasing the hypnotic effect of pentobarital sodium in mice.
TCMBANKHE003725 Rhizoma Zingiberis Recens 生姜 To induce perspiration and dispel cold, to warm the stomach and arret vomiting, and to resolve phlegm and relieve cough./Wind-cold common cold, fever and aversion to wind, headache and nasal congestion, vomiting, phlegm-rheum cough asthma, distention fullness, diarrhea.
TCMBANKHE003752 Radix Salviae liguliobae 丹参 To remove blood stasis and relieve pain, to promote the flow of blood and stimulate menstrual discharge, and to ease the mind./Angina pectoris, cerebral atherosclerosis, diffusive intravascular clotting, thrombophlebitis, hepatitis, acute surgical infection, mastitis, erysipelas, otitis media, tonsillitis, bone marrow infection, menstrual disorder, dysmenorrhea, amenorrhea, postpartum stasis stagnation abdominal pain, pain in heart and abdomen, concretion conglomeration accumulation and gathering, heat impediment swelling and pain, knocks and falls, heat entering construction-blood, vexation and agitation, insomnia and vexation, swelling toxin of welling abscess and sore, zoster, neurodermatitis, psoriasis.
TCMBANKHE005959 Teucrium bidentatum 二齿香科科 To dispel wind, disinhibit damp, resolve toxin./Common cold, headache, nasal congestion, dysentery, eczema, eczema leukoplakia.
TCMBANKHE008098 Radix Curcumae 郁金 1. To invigorate blood and stop pain; 2. To promote qi circulation and release stagnation; 3. To cool blood and clear heat in the heart; 4. To relieve jaundice and facilitate gall bladder function/See Curcuma longa.
TCMBANKHE006575 Atractylodes chinensis 北苍术 See Atractylodes lancea ./See Atractylodes lancea .
TCMBANKHE009036 Cacumen et Folium Biotae 侧柏叶 To arrest bleeding by removing heat from blood, and to promote the growth of black hair./Hemoptysis, duodenal bleeding, chronic bronchitis, tuberculosis, blood ejection, spontaneous external bleeding, hematuria, hematochezia, blood dysentery, incessant flooding and spotting, cough with profuse phlegm, wind-damp impediment pain, erysipelas, epidemic parotitis, scalds, burns.
TCMBANKHE005239 Fructus Aurantii 枳壳 To regulate the flow of qi, remove its stagnation, and alleviate distension;Treatment of distension and pain in the chest and hypochondriac regions due to stagnation of qi, indigestion with retention of phlegm and fluid, gastroptosis, prolapse of the rectum, prolapse of the uterus./Phlegm stagnation in chest and diaphragm, glomus in chest, distention in rib-side, food accumulation, retching counterflow.
TCMBANKHE005760 Craibiodendron yunnanese 金椰子 To dispel wind and quicken blood, free network vessels and relieve pain./Impediment pain, hemiplegia, knocks and falls.
TCMBANKHE006133 紫苏 Phlegm congestion and qi counterflow, cough and asthma, intestinal dry and constipation.
TCMBANKHE008616 Herba Bidentis 鬼针草 1. To clear the superficial heat. 2. To clear heat and toxic materials. 3. To clear dampness and heat from the gastrointestines./Swelling pain in throat, dysentery, diarrhea, jaundice, intestinal welling abscess, swelling toxin of clove sore, snake or insect bites, wind-damp impediment pain, knocks and falls.
TCMBANKHE009030 Resi myrrhae;Myrrha 没药 1. To invigorate blood and stop pain; 2. To reduce swelling and promote healing/Stasis pain in chest and abdomen, amenorrhea, dysmenorrhea, concretion and conglomeration, knocks and falls, swollen welling abscess and sores, intestinal welling abscess, red eyes with gall.
TCMBANKHE004757/XU-374 Fructus Cnidii|Cnidium monnieri 蛇床子|蛇床 贵州省黔南州望谟县 To warm the kidney and promote virility, to remove damp, to dispel zvind, and to kill parasites./Impotence, scrotal damp itch, vaginal discharge, pudendal itch, trichomoniasis, eczema, infertility due to uterus cold, wind-damp impediment pain, scab and lichen, damp sore.
TCMBANKHE008995 Citrus junos 橙子皮 To transform phlegm, disinhibit diaphragm, disperse food, check vomiting./Qi stagnation in chest and diaphragm, cough with profuse phlegm, non-digestion of food accumulation, nausea and vomiting, drunkenness.
TCMBANKHE007520 Fructus Amomi 砂仁 To eliminate damp and improve appetite, to warm the spleen and check diarrhea, and to prevent abortion./Abdominal pain glomus distention, food stagnation in torpid stomach, dysphagia-occlusion, vomiting, cold dysentery, stirring fetus in pregnancy.
TCMBANKHE007781 Herba Asari 细辛 To dispel wind-cold, to relieve nasal obstruction, to alleviate pain and to remove retained fluid./Wind-cold common cold, influenza, headache, toothache, local anesthesia, nasal congestion, deep-source nasal congestion, wind-damp impediment pain, phlegm-rheum cough asthma.
TCMBANKHE007773/YEM-590/XU-716 Ramulus Mori|Morus alba L.|Morus alba 桑枝|桑 桑叶 云南民族药物志:第三卷|云南省昭通市盐津县 To relieve rheumatic arthralgia./Hypertension, aching pain in joints, numbness in joints. 阿昌族/布依族/傣族/德昂族/哈尼族/景颇族/傈僳族/苗族/水族/佤族/彝族/藏族
TCMBANKHE005416/YEM-639/XU-540 Cortex Toonae Sinensis|Ailanthus altissima(Mill.)Swingle|Ailanthus altissima 椿根皮,椿皮|臭椿 臭椿 云南民族药物志:第四卷|云南省大理州下关 Treatment of morbid leukorrhea, diarrhea caused by damp-heat, chronic diarrhea, chronic dysentery, hematochezia, abnormal uterine bleeding, to remove damp-heat and arrest discharges./Treatment of morbid leukorrhea, diarrhea caused by damp-heat, chronic diarrhea, chronic dysentery, hematochezia, abnormal uterine bleeding. 瑶族/彝族
TCMBANKHE005377/YEM-788 Herba Eupatorii|Eupatorium fortunei Turcz. 佩兰 水泽兰 云南民族药物志:第四卷 To resolve damp, invigorate the function of the spleen and improve appetite by its spicy fragrance, and to expel summer heat from the body surface./Nausea and vomiting, bad breath, drooling, distended head and oppression in chest, sweet-greasy in mouth, summerheat-damp exterior syndrome. 阿昌族/傣族/德昂族/哈尼族/基诺族/景颇族/拉祜族/傈僳族/苗族/彝族
TCMBANKHE004691/YEM-353/YEM-961 Fructus Amomi|Amomum villosum Lour. 缩砂仁; 砂仁|阳春砂 阳春砂仁 云南民族药物志:第五卷 Treatment of accumulation of damp in the spleen and the stomach marked by epigastric stuffieness and anorexia, vomiting and diarrhea in deficiency cold syndrome of the spleen and the stomach, pernicious vomiting of pregnancy, threatened abortion.; To eliminate damp and improve appetite, to warm the spleen and check diarrhea, and to prevent abortion./1. Its decoction lower thab 1% concentration stimulates and that higher than 1% or the saturated solution of its volatile oil inhibits the intestines of guinea-pigs in vitro.2. Its volatile oil acts as stomachic tonic and exaggerates the diacharge of flatus.; Abdominal pain glomus distention, food stagnation in torpid stomach, dysphagia-occlusion, vomiting, cold dysentery, stirring fetus in pregnancy. 阿昌族/傣族/德昂族/哈尼族/景颇族/傈僳族/瑶族/彝族/壮族

   植物对应的疾病
疾病ID 病名 疾病类型 MeSH 参考文献

   化合物对应的靶点
靶点ID 基因名 基因别名 描述
TCMBANKGE000476 NCOA2 GRIP1; KAT13C; NCoA-2; SRC2; TIF2; bHLHe75 nuclear receptor coactivator 2
TCMBANKGE000766 ACHE ACEE; ARACHE; N-ACHE; YT acetylcholinesterase (Cartwright blood group)
TCMBANKGE000813 DPP4 ADABP; ADCP2; CD26; DPPIV; TP103 dipeptidyl peptidase 4
TCMBANKGE001073 PTGS2 COX-2; COX2; GRIPGHS; PGG/HS; PGHS-2; PHS-2; hCox-2 prostaglandin-endoperoxide synthase 2
TCMBANKGE001755 MAOB - monoamine oxidase B
TCMBANKGE006339 CA2 CA-II; CAC; CAII; Car2; HEL-76; HEL-S-282 carbonic anhydrase 2
TCMBANKGE008921 RXRA NR2B1 retinoid X receptor alpha
TCMBANKGE009256 SLC6A2 NAT1; NET; NET1; SLC6A5 solute carrier family 6 member 2
TCMBANKGE014050 GABRA1 ECA4; EIEE19; EJM; EJM5 gamma-aminobutyric acid type A receptor subunit alpha1
TCMBANKGE014941 DPEP1 MBD1; MDP; RDP dipeptidase 1