Compound Summary


  Compound Information

药名:

fangchinoline

别名:

FT-0686612; N1799; ZINC85541034; NSC277171; THALRUGOSINE; thalrugosine; N1799; ZINC85541034; NSC277171; THALRUGOSINE

分子式:

C37H40N2O6

Smiles:

CN1CCC2=CC(=C3C=C2C1CC4=CC=C(C=C4)OC5=C(C=CC(=C5)CC6C7=C(O3)C(=C(C=C7CCN6C)OC)O)OC)OC

成分:

HBIN026356;HBIN046230

SymMap_id:

SMIT15379;SMIT17933

TCMID_id:

7713;21254

PubChem_id:

5458555


   化合物对应的植物
植物ID 拉丁名 药用植物名 药名 来源 功能与主治 使用民族
TCMBANKHE001044 Radix Stephaniae Tetrandrae 粉防己 For arthralgia, especially of heat type, also for acrodynia of dampness-heat type, trauma, periarthritis of joint and angina pectoris. For edema nad dysuria. In ancient times, used for dyspneic cough due to withered lung or heat-heat, for hemoptysis with abundant expectoration due to withered lung, used together with Semen Lepidii seu Descurainiae. Recently, use for bronchial asthma, asthmatic bronchitis, silicosis, pulmonary tuberculosis, etc. For hypertension, especially that complicated by coronary heart diseases. For carcinoma of lung, and squamous cell epithioma(decreasing the dosage of radiotherapy by one-third to one-fourth and minimizing the occurrence of side effect)./1. Hanfangchin A and B are two active components, which have an anti-inflammatory effect.2. Anti-allergic, inhibiting the release of histamine.3. Promting phagocytosis.4. Dilating coronary artery and decreasing myocardial oxygen consumption.5. Inhibiting the growth of Bacillus tuberculosis, Staphylococcus aureus and ameba.6. High dosage may induce respiratory inhibition and cardiac arrest.
TCMBANKHE002730 橘络
TCMBANKHE002762 Radix et Rhizoma Thalictri 马尾莲 Influenza, fever in children, common cold with fever, measles papules, malaria, damp-heat diarrhea dysentery, jaundice, red eyes with gall.
TCMBANKHE003194 Thalictrum rugosum 走稳唐松草
TCMBANKHE005818 Thalictrum lucidum 透明唐松草
TCMBANKHE004731 Thalictrum alpinum 高山唐松草 To clear heat and drain fire, resolve toxin./Headache and red eyes, diarrhea, dysentery, sores.
TCMBANKHE007036 Cyclea barbata 银不换 To clear heat and resolve toxin, disperse stasis and relieve pain, disinhibit urine and free strangury./Wind-heat common cold, throat pain, toothache, stomachache, abdominal pain, damp-heat dysentery, malaria, dribbling pain of urination, painful wound from knocks and falls, sprain and contusion.
TCMBANKHE005259 Aristolochia heterophylla 汉防己 To dispel wind and relieve pain, clear heat and disinhibit water./Rheumatic pain in joints, damp-heat pain in limbs, edema, inhibited urination, beriberi with edema.
TCMBANKHE005281 Mahonia repens 匍匐十大功劳
TCMBANKHE008108 Thalictrum rugosum 绉纹唐松草
TCMBANKHE009013 Cortex Illicii 地枫皮 To relieve rheumatic conditions, and to promote the flow of qi and relieve pain./Pain in joints due to rheumatalgia, taxation damage in lumbar muscle, centipede bite.
TCMBANKHE007238 Radix Stephaniae Tetrandrae 防己 To cause diuresis and to relieve rheumatic conditions./Beriberi with edema, inhibited urination, eczema, sore toxin, wind-damp impediment pain, hypertension, adjuvant in anesthesia.
TCMBANKHE007752 Thalictrum minus 小唐松草
TCMBANKHE005418/YNS-102 Rhizoma Polygoni cuspidati|Polygonum cuspidatum Sieb.et Zucc. 虎杖 虎杖叶 云南药材标准:第一册 平肝潜阳,祛痰息风。用于肝阳上亢,血压偏高,头晕头昏|To dispel wind and damp, to eliminate blood stasis and alleviate pain, to relieve cough, and to resolve phlegm./Hyperlipemia, impediment pain in joints, damp-heat jaundice, toxic jaundice, child jaundice, amenorrhea, hepatitis, appendicitis, candida vaginitis, concretion and conglomeration, cough with profuse phlegm, burns and scalds, knocks and falls, swelling toxin of welling abscess and sore.
TCMBANKHE003989/YEM-614 Stephania hernandifolia|Stephania hernandifolia (Willd.) Walp. 汝南|桐叶千金藤 南千斤藤 云南民族药物志:第三卷 To clear heat and resolve toxin, dispel wind-damp, relieve pain./Sore toxin of welling abscess and boil, swelling pain in throat, epidemic parotitis, wind-damp impediment pain, dysentery, headache, stomachache, taxation damage and pain. 傣族

   植物对应的疾病
疾病ID 病名 疾病类型 MeSH 参考文献
TCMBANKDI015496 Liver neoplasms group Digestive System Diseases; Neoplasms 21418191

   化合物对应的靶点
靶点ID 基因名 基因别名 描述
TCMBANKGE000269 ATG5 APG5; APG5-LIKE; APG5L; ASP; SCAR25; hAPG5 autophagy related 5
TCMBANKGE000770 SESN2 HI95; SES2; SEST2 sestrin 2
TCMBANKGE001106 MTOR FRAP; FRAP1; FRAP2; RAFT1; RAPT1; SKS mechanistic target of rapamycin kinase
TCMBANKGE001112 PRKAB1 AMPK; HAMPKb protein kinase AMP-activated non-catalytic subunit beta 1
TCMBANKGE001127 PRKAA1 AMPK; AMPKa1 protein kinase AMP-activated catalytic subunit alpha 1
TCMBANKGE001128 PRKAA2 AMPK; AMPK2; AMPKa2; PRKAA protein kinase AMP-activated catalytic subunit alpha 2
TCMBANKGE001177 TP53 BCC7; BMFS5; LFS1; P53; TRP53 tumor protein p53