Plant Summary
Plant Information
TCMBank_ID: | TCMBANKHE005259 |
ID: | TCMBANKHE005259 |
植物拉丁名: |
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功能与主治: | To dispel wind and relieve pain, clear heat and disinhibit water./Rheumatic pain in joints, damp-heat pain in limbs, edema, inhibited urination, beriberi with edema. |
药用植物名: | 汉防己 |
药用部位: | root |
药味: | Cold; Pungent; Bitter |
经络: | Bladder; Spleen; Kidney |
临床特征: | 1. Hanfangchin A and B are two active components, which have an anti-inflammatory effect.2. Anti-allergic, inhibiting the release of histamine.3. Promting phagocytosis.4. Dilating coronary artery and decreasing myocardial oxygen consumption.5. Inhibiting |
治疗类型: | 祛风湿 |
TCM_ID_id: | 7149 |
TCMSP_id: | 315 |
植物对应的化合物
| 化合物ID | 化合物名 | 别名 | 分子式 | 分子质量 | Smiles |
|---|
| TCMBANKIN014902 | 7-hydroxy-aristolochicacid a | 7-hydroxy-aristolochic acid a | C17H11NO8 | 357.3 g/mol | COC1=C(C=CC2=C3C(=C(C=C21)[N+](=O)[O-])C(=CC4=C3OCO4)C(=O)O)O |
| TCMBANKIN032286 | Magnograndiolide | magnograndiolide; (3aS,6R,6aR,9R,9aS,9bS)-6,9-dihydroxy-6,9-dimethyl-3-methylidene-3a,4,5,6a,7,8,9a,9b-octahydroazuleno[5,4-d]furan-2-one; SCHEMBL18334098; CHEMBL2206436; (3as,6r,6ar,9r,9as,9bs)-6,9-dihydroxy-6,9-dimethyl-3-methylidene-3a,4,5,6a,7,8,9a,9b-octahydroazuleno[5,4-d]furan-2-one; (3aS,6R,6aR,9R,9aS,9bS)-6,9-dihydroxy-6,9-dimethyl-3-methylene-3a,4,5,6a,7,8,9a,9b-octahydroazuleno[5,4-d]furan-2-one; 92618-98-9; AC1NSXRC; (3aS,6R,6aR,9R,9aS,9bS)-6,9-dihydroxy-6,9-dimethyl-3-methylidene-3a,4,5,6a,7,8,9a,9b-octahydroazuleno[4,5-b]furan-2-one | C15H22O4 | 266.33 | CC1(CCC2C(C3C1CCC3(C)O)OC(=O)C2=C)O |
| TCMBANKIN038736 | 3beta-Hydroxy-atractylon | 3beta-hydroxy-atractylon | C15H20O2 | 232.318 | C1([H])([H])C([H])([H])[C@](C([H])([H])[H])(C([H])([H])c(oc([H])c2C([H])([H])[H])c2C3([H])[H])[C@]3([H])C(=C([H])[H])[C@]1([H])O[H] |
| TCMBANKIN045064 | Aristophyllide A | 557.6 g/mol | |||
| TCMBANKIN049229 | Tetraneurin A | tetraneurin-A; CHEMBL374816; CHEBI:9498; DTXSID40177144; [(3aS,6R,6aR,9aS,9bR)-6a-hydroxy-9a-methyl-3-methylene-2,9-dioxo-4,5,6,7,8,9b-hexahydro-3aH-azuleno[8,7-b]furan-6-yl]methyl acetate; 22621-72-3; acetic acid [(3aS,6R,6aR,9aS,9bR)-6a-hydroxy-9a-methyl-3-methylene-2,9-dioxo-4,5,6,7,8,9b-hexahydro-3aH-azuleno[8,7-b]furan-6-yl]methyl ester; C09559; acetic acid [(3aS,6R,6aR,9aS,9bR)-6a-hydroxy-2,9-diketo-9a-methyl-3-methylene-4,5,6,7,8,9b-hexahydro-3aH-azuleno[7,8-d]furan-6-yl]methyl ester; [(3aS,6R,6aR,9aS,9bR)-6a-hydroxy-9a-methyl-3-methylidene-2,9-dioxo-4,5,6,7,8,9b-hexahydro-3aH-azuleno[8,7-b]furan-6-yl]methyl ethanoate; tetraneurin a; [(3aS,6R,6aR,9aS,9bR)-6a-hydroxy-9a-methyl-3-methylidene-2,9-dioxo-4,5,6,7,8,9b-hexahydro-3aH-azuleno[4,5-b]furan-6-yl]methyl acetate; AC1L5BPC; [(3aS,6R,6aR,9aS,9bR)-6a-hydroxy-9a-methyl-3-methylidene-2,9-dioxo-4,5,6,7,8,9b-hexahydro-3aH-azuleno[8,7-b]furan-6-yl]methyl acetate; [(3aS,6R,6aR,9aS,9bR)-6a-hydroxy-9a-methyl-3-methylene-2,9-dioxo-4,5,6,7,8,9b-hexahydro-3aH-azuleno[4,5-b]furan-6-yl]methyl acetate | 322.35 | ||
| TCMBANKIN057998 | magnoflorine | NSC150447; AKOS025401511; Magnoflorine; Escholine Iodide; C20H24NO4.I; Magnoflorine, iodide; Thalictrine Iodide; Magnoflorine Iodide (6CI,7CI); N2506; AC-20269; 4H-Dibenzo(de,g)quinolinium, 5,6,6a,7-tetrahydro-1,11-dihydroxy-2,10-dimethoxy-6,6-dimethyl-, iodide, (S)-; Magnoflorine-iodide; NSC 150447; MAGNOFLORINE IODIDE; MAGNOFLORINE IODIDE, (+)-(RG); Magnoflorineiodide; BG01755204; (+)-Magnoflorine Iodide; CHEMBL494052; Corytuberine Methiodide; MolPort-006-069-296; NSC-150447; 4277-43-4; (+)-MAGNOFLORINE IODIDE; 1,11-Dihydroxy-2,10-dimethoxy-6-methyl-6a; AK608288; A-aporphinium Iodide; 8167AH; DTXSID00195420; (6aS)-5,6,6a,7-Tetrahydro-1,11-dihydroxy-2,10-dimethoxy-6,6-dimethyl-4H-dibenzo[de,g]quinolinium Iodide; magnoflorine; (+)-magnoflorine | C20H24NO4+ | 342.4 g/mol | C[N+]1(CCC2=CC(=C(C3=C2C1CC4=C3C(=C(C=C4)OC)O)O)OC)C |
| TCMBANKIN058005 | cissamine | DTXSID00171789; 18556-27-9; 6H-Dibenzo(a,g)quinolizinium, 5,8,13,13a-tetrahydro-2,9-dihydroxy-3,10-dimethoxy-7-methyl-, (7S-cis)-; AC1MIY8A; (S,S)-N-methylscoulerine; (7S,13aS)-2,9-dihydroxy-3,10-dimethoxy-7-methyl-5,8,13,13a-tetrahydro-6H-isoquinolino[3,2-a]isoquinolinium; (7S,13aS)-3,10-dimethoxy-7-methyl-6,8,13,13a-tetrahydro-5H-isoquinolino[2,1-b]isoquinolin-7-ium-2,9-diol; Cyclanoline; ZINC255226625; CHEBI:76923; S-trans-cyclanoline; (S)-cis-N-methylscoulerine; (6S,12BS)-4,11-DIHYDROXY-3,10-DIMETHOXY-6-METHYL-7,8,12B,13-TETRAHYDRO-5H-6-AZATETRAPHEN-6-IUM; Cissamine;cyclanoline | C20H24NO4+ | 342.4 g/mol | C[N+]12CCC3=CC(=C(C=C3C1CC4=C(C2)C(=C(C=C4)OC)O)O)OC |
| TCMBANKIN060055 | 3β-hydroxyatractylone | C15H20O2 | 232.32 g/mol | CC1=COC2=C1CC3C(=C)C(CCC3(C2)C)O | |
| TCMBANKIN061345 | fangchinoline | FT-0686612; N1799; ZINC85541034; NSC277171; THALRUGOSINE; thalrugosine; N1799; ZINC85541034; NSC277171; THALRUGOSINE | C37H40N2O6 | 608.7 g/mol | CN1CCC2=CC(=C3C=C2C1CC4=CC=C(C=C4)OC5=C(C=CC(=C5)CC6C7=C(O3)C(=C(C=C7CCN6C)OC)O)OC)OC |
| TCMBANKIN061346 | tetrandrine | NCI60_042029; IDI1_033949; MLS000728516; Spectrum3_000659; Spectrum2_000025; Prestwick2_000670; Berbaman, 6,6',7,12-tetramethoxy-2,2'-dimethyl-, (1-beta)- (9CI); NSC77037; Berbaman, 6,6',7,12-trtramethoxy-2,2'-dimethyl-, (1.beta.)-(PM)-; Berbaman, 6,6',7,12-trtramethoxy-2,2'-dimethyl-, (1beta)-(PM)- (9CI); SPECTRUM1504185; Spectrum_000315; BSPBio_001479; Berbaman, 6,6',7,12-tetramethoxy-2,2'-dimethyl-, (1.beta.)-; Prestwick0_000670; A828808; AIDS-032943; (S,S)-(+)-Tetrandrine; CBiol_001914; 2-27-00-00889 (Beilstein Handbook Reference); T2695_SIGMA; SpecPlus_000661; SMR000445630; KBioGR_001178; Tetrandrine; SDCCGMLS-0066758.P001; NCGC00142549-02; C09654; NSC91771; Spectrum4_000619; SPBio_000089; KBio2_000795; KBio3_000398; D-Tetrandrine; NCGC00142549-01; KBio3_000397; Fanchinine; BSPBio_002297; TETRANDRINE, (DL); Bio1_000200; AIDS032943; KBio2_003363; NCGC00142549-03; Tetrandrin; Berbaman, 6,6',7,12-trtramethoxy-2,2'-dimethyl-, (1beta)-(PM)-; (+/-)-Tetrandine; SPBio_002660; DivK1c_006757; tetrandrine ; BPBio1_000813; ST057602; FF-0019; KBioGR_000199; KBio1_001701; Bio2_000679; Spectrum5_001366; KBio2_005931; (.+-.)-Tetrandrine; (1beta)-6,6',7,12-Tetramethoxy-2,2'-dimethylberbaman; 518-34-3; Berbaman, 6,6',7,12-tetramethoxy-2,2'-dimethyl-, (1beta)- (9CI); KBioSS_000199; KBioSS_000795; (S,S)-()-Tetrandrine; KBio2_000199; (+-)-Tetrandine; DL-Tetrandine; (S,S)-Tetrandrine; NSC 77037; Bio1_000689; DL-Tetrandine; (+)-Tetrandrine; Hanfangchin A; 6,7-dimethoxy-1-[(4-methoxyphenyl)methyl]-2-methyl-3,4-dihydro-1H-isoquinoline; 6-methoxy-2-methyl-1-(phenylmethyl)-3,4-dihydro-1H-isoquinoline; dihydrate; AIDS-027689; BRN 0877811; 365629_ALDRICH; Bio2_000199; Sinomenine A; KBio2_005335; Bio1_001178; Berbaman, 6,6',7,12-tetramethoxy-2,2'-dimethyl-, (1-beta)-; NSC 91771; AIDS027689; BSPBio_000739; KBio3_001517; DL-Tetandrine; Prestwick3_000670; CCRIS 2705; Prestwick1_000670; 23495-89-8; HSCI1_000014; KBio2_002767; NCI60_041696; (+-)-Tetrandine; NCI60_042029; IDI1_033949; BCP0726000284; MLS000728516; Spectrum3_000659; NCGC00017376-10; AB00513883; S-(+)-Tetrandrine; Spectrum2_000025; HY-13764; (1S,14S)-9,20,21,25-tetramethoxy-15,30-dimethyl-7,23-dioxa-15,30-diazaheptacyc lo[22.6.2.2<3,6>.1<8,12>.1<14,18>.0<22,36>.0<27,31>]hexatriaconta-3(33),4,6(34 ),8(35),9,11,18(36),19,21,24,26,31-dodecaene; HMS3402J21; Prestwick2_000670; NSC77037; HMS1570E21; d-Tetrandr; Tetrandrine, analytical standard, for drug analysis; Berbaman, 6,6',7,12-trtramethoxy-2,2'-dimethyl-, (1beta)-(PM)- (9CI); SR-01000779899-6; 29EX23D5AJ; SPECTRUM1504185; Spectrum_000315; BSPBio_001479; BBL029400; CS-0007782; Prestwick0_000670; HMS1791J21; LS-148949; (S,S)-(+)-Tetrandrine; W-2768; 16H-1,24:6,9-Dietheno-11,15-metheno-2H-pyrido[2',3':17,18][1,11]dioxacycloeicosino[2,3,4-ij]isoquinoline, 3,4,4a,5,16a,17,18,19-octahydro-12,21,22,26-tetramethoxy-4,17-dimethyl-, (4aS,16aS)-; CBiol_001914; Tetrandrine (Fanchinine); 2-27-00-00889 (Beilstein Handbook Reference); SMR000445630; SpecPlus_000661; KBioGR_001178; NCGC00182717-01; AC1L2J88; SDCCGMLS-0066758.P001; UNII-29EX23D5AJ; NCGC00142549-02; C09654; CHEBI:49; NSC91771; Spectrum4_000619; SPBio_000089; KBio2_000795; AC1Q58EO; iso-tetrandrine; HMS1361J21; AS-15343; KBio3_000398; (1S,14S)-9,20,21,25-tetramethoxy-15,30-dimethyl-7,23-dioxa-15,30-diazaheptacyc lo[22.6.2.2<3,6>.1<8,12>.1<14,18>.0<22,36>.0<27,31>]hexatriaconta-3(33),4,6(34 ),8(35),9,11,18(36),19,21,24,26,31-dodecae; D-Tetrandrine; KBio3_000397; NCGC00017376-05; Fanchinine; NCGC00142549-01; Q-100580; BSPBio_002297; Tetrandrine, Millenia Hope; SR-01000779899-7; TETRANDRINE, (DL); (1.beta.)-6,6',7,12-Tetramethoxy-2,2'-dimethylberbaman; ZINC28116057; S,S-(+)-Tetrandrine; Bio1_000200; D0G4ES; KBio2_003363; NCGC00142549-03; SR-01000779899; Tetrandrine, European Pharmacopoeia (EP) Reference Standard; 6490-80-8; D0AN2Q; BRD-8237; Tetrandrin; Berbaman, 6,6',7,12-trtramethoxy-2,2'-dimethyl-, (1beta)-(PM)-; HMS2097E21; 916770-74-6; CCG-38342; (+/-)-Tetrandine; HMS1989J21; Berbaman,6',7,12-trtramethoxy-2,2'-dimethyl-, (1.beta.)-(PM)-; SPBio_002660; Tetrandrine - Fanchinine; NCGC00017376-06; DivK1c_006757; 6,6',7,12-tetramethoxy-2,2'-dimethyl-1 beta-berbaman; BB_NC-1040; Tetrandrine, West Virginia University; BPBio1_000813; ST057602; STK801908; FF-0019; KBioGR_000199; AB0016761; NSC-77037; KBio1_001701; 607379-81-7; Bio2_000679; Isotetrandrine; Spectrum5_001366; KBio2_005931; (.+-.)-Tetrandrine; (1beta)-6,6',7,12-Tetramethoxy-2,2'-dimethylberbaman; 518-34-3; BRD-K08078237-001-07-3; Tetrandrine(Fanchinine); SR-01000779899-5; CHEMBL176045; DTXSID10178062; KBioSS_000199; NCGC00017376-04; tetradrine; MLS002153946; S2403; (1S,14S)-9,20,21,25-tetramethoxy-15,30-dimethyl-7,23-dioxa-15,30-diazaheptacyclo[22.6.2.2^{3,6}.1^{8,12}.1^{14,18}.0^{27,31}.0^{22,33}]hexatriaconta-3,5,8(34),9,11,18,20,22(33),24,26,31,35-dodecaene; KBioSS_000795; (1S,14S)-9,20,21,25-TETRAMETHOXY-15,30-DIMETHYL-7,23-DIOXA-15,30-DIAZAHEPTACYCLO[22.6.2.2_,?.1?,__.1_?,_?.0_?,__.0__,__]HEXATRIACONTA-3,5,8(34),9,11,18(33),19,21,24,26,31,35-DODECAENE; SCHEMBL20119; tetrandrine; KBio2_000199; AN-8470; O972; C38H42N2O6; (S,S)-Tetrandrine; NSC 77037; Bio1_000689; DL-Tetrandine; NCGC00142549-04; (+)-Tetrandrine; BG00889113; HMS2232C06; Hanfangchin A; 518T343; BRN 0877811; (11S,31S)-16,36,37,54-tetramethoxy-12,32-dimethyl-11,12,13,14,31,32,33,34-octahydro-2,6-dioxa-1(7,1),3(8,1)-diisoquinolina-5(1,3),7(1,4)-dibenzenacyclooctaphane; MCULE-2548279289; Bio2_000199; AC-7987; Berbaman, 6,6',7,12-trtramethoxy-2,2'-dimethyl-, (1beta)-(+-)-; Sinomenine A; KBio2_005335; MFCD08689909; Tranex-18; SR-01000779899-9; WVTKBKWTSCPRNU-KYJUHHDHSA-N; Bio1_001178; Berbaman,6',7,12-tetramethoxy-2,2'-dimethyl-, (1.beta.)-; MolPort-000-763-034; Berbaman, 6,6',7,12-tetramethoxy-2,2'-dimethyl-, (1-beta)-; NSC 91771; BSPBio_000739; Berbaman, 6,6',7,12-tetramethoxy-2,2'-dimethyl-, (1beta)-; NCGC00017376-03; KBio3_001517; hanjisong; DL-Tetandrine; SC-14047; Prestwick3_000670; NCGC00017376-02; tetramethoxy(dimethyl)[?]; CCRIS 2705; Prestwick1_000670; AKOS004119881; BRD8237; 23495-89-8; HSCI1_000014; KBio2_002767; NSC-91771; NCI60_041696; (+-)-Tetrandine; hanfangchin a | C38H42N2O6 | 622.7 g/mol | CN1CCC2=CC(=C3C=C2C1CC4=CC=C(C=C4)OC5=C(C=CC(=C5)CC6C7=C(O3)C(=C(C=C7CCN6C)OC)OC)OC)OC |
| TCMBANKIN061873 | aristolochicacid | 8-Methoxy-3,4-methylendioxxy-10-nitro-1-phenanthrencarbonsaeure; NCGC00095981-03; aristolochic acid; API0000398; TNP00273; MolPort-001-797-985; Bio1_000907; DivK1c_006544; Aristolochind; 8-METHOXY-6-NITROPHENANTHROL(3,4-D)-1,3-DIOXIDE-5-; IDI1_033910; Aristolochin; NCIMech_000812; C-20352; 8-methoxy-6-nitro-2H-phenanthro[3,4-d]1,3-dioxolene-5-carboxylic acid; aris-tolochic acid; Phenanthro(3,4-d)-1,3-dioxole-5-carboxylic acid, 8-methoxy-6-nitro-; NCGC00017334-04; HMS1791H22; CTK4G6973; CC-24181; KBio2_004204; KBio2_006772; SC-14173; NSC 11926; KBioGR_002387; DTXSID0040969; Aristolochic acid I, powder; SR-05000002369-3; CHEBI:2825; 8-Methoxy-6-nitrophenanthro[3,4-d][1,3]dioxole-5-carboxylic acid; Spectrum2_000822; KBioSS_001636; KBio3_002068; CCG-36162; 8-METHOXY-6-NITROPHENANTHROL(3,4-D)-1,3-DIOXIDE-5-CARBOXYLIC ACID; CCRIS 1544; NCGC00095981-04; 61117-05-3; NCGC00095981-02; 313A677; SPBio_000743; 8-Methoxy-6-Nitrophenanthol-(3,4-d)-1,3-Dioxole-5-Carboxylic Acid; I07-0211; ZINC52; Q-100394; C17H11NO7; AB0028965; NCI60_000460; C08469; Aristolochic acid 1; Spectrum5_000729; KBio2_002728; TR 1736; 8-methoxy-6-nitronaphtho[2,1-g][1,3]benzodioxole-5-carboxylic acid; MLS002695974; Aristolochid; ST50307164; SCHEMBL166284; 313-67-7; KBioGR_000160; Phenanthro[3,4-d]-1,3-dioxole-5-carboxylic acid, 8-methoxy-6-nitro-; Bio2_000640; Ambotz313-67-7; Aristolochic acid I, European Pharmacopoeia (EP) Reference Standard; Tardolyt; AC1L1D86; NSC 50413; KBio2_005296; 8-Methoxy-6-nitro-phenanthro[3,4-d][1,3]dioxole-5-carboxylic acid; 8-methoxy-6-nitro-2H-phenanthro[4,3-d]1,3-dioxolene-5-carboxylic acid; NSC50413; 94218WFP5T; BSPBio_001440; SR-05000002369-2; CHEMBL93353; 3,4-Methylenedioxy-8-methoxy-10-nitro-1-phenanthrenecarboxylic acid; HMS1361H22; N2032; FT-0602867; NCGC00017334-01; LS-21656; Aristolochic acid I; ST057179; Bio1_001396; HMS3402H22; Aristolochiazaeure; KBio3_000319; 8-methoxy-6-nitrophenanthro(3,4-d)-1,3-dioxole-5-carboxylic acid; NCGC00095981-01; AKOS015896751; Aristolochia yellod; HSDB 7179; NCGC00017334-07; NSC11926; Descresepd; BBFQZRXNYIEMAW-UHFFFAOYSA-N; Aristolochic-acid-A; Spectrum_001156; MFCD00004996; AN-319; KBio3_000320; NSC-50413; NCGC00017334-06; ARISTOLOCHINE; UNII-94218WFP5T; MLS002702976; X1086; NSC-11926; Aristolochic acid-I; 8-Methoxy-6-nitrophenanthol (3,4-d) 1,3-dioxole-5-carboxylic acid; EINECS 206-238-3; KBio2_000160; SPECTRUM1502233; NCGC00017334-03; Bio1_000418; TR-013344; 8-methoxy-6-nitro-naphtho[2,1-g][1,3]benzodioxole-5-carboxylic acid; NCGC00095981-05; SR-05000002369; Phenanthro[3,3-dioxole-5-carboxylic acid, 8-methoxy-6-nitro-; BSPBio_002848; HMS1989H22; BDBM50306855; Aristinic acid; Bio2_000160; NCGC00017334-05; 8-Methoxy-3,4-methylenedioxy-10-nitrophenanthrene-1-carboxylic acid; Aristolochia, European Pharmacopoeia (EP) Reference Standard; SpecPlus_000448; Aristolochic acid A; Birthwort; Spectrum3_001114; KBioSS_000160; CCG-35796; Phenanthro[3,4-d]-1,3-dioxole-5-carbocylic acid, 8-methoxy-6-nitro-; MCULE-3861334509; NCGC00017334-02; KBio1_001488; Aristolochic acid; 8-Methoxy-6-nitrophenanthro[3,4-d][1,3]dioxole-5-carboxylic acid #; 12770-90-0; KBio2_001636; Spectrum4_001952; BRN 0345159; A000071790; Tardolyd; SMR001562128;aristolochic acid A;aristolochic acid a | C17H11NO7 | 341.27 g/mol | COC1=CC=CC2=C3C(=C(C=C21)[N+](=O)[O-])C(=CC4=C3OCO4)C(=O)O |
植物对应的疾病
| 疾病ID | 病名 | 疾病类型 | MeSH | 参考文献 |
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植物对应的靶点
| 靶点ID | 基因名 | 基因别名 | 描述 | 染色体位置 | Map_Location | 基因类型 |
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