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疾病ID:TCMBANKDI002730
疾病名:Hereditary Leiomyomatosis and Renal Cell Cancer
MeSH_Name:Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Skin and Connective Tissue Diseases
HPO_Name:Abnormality of the integument; Neoplasm
UMLS_Name:Neoplastic Process
DO_Name:-
疾病类型:disease
DisGeNET_Link:C1708350
MeSH_Link:C16; C04; C13; C17
HPO_Link:HP:0001574; HP:0002664
UMLS_Link:T191
DO_Link:-
HERB_ID:-
疾病对应的植物
| ID | 拉丁名 | 药名 | 药用植物名 | 功能与主治 | 来源 | 药用部位 | 使用民族 |
|---|
疾病对应的化合物
| 化合物ID | 化合物名 | 别名 | 分子式 | 分子质量 | Smiles |
|---|
疾病对应的靶点
| 靶点ID | 基因名 | 基因别名 | 描述 |
|---|
| TCMBANKGE000453 | NR1I3 | CAR; CAR1; MB67 | nuclear receptor subfamily 1 group I member 3 |
| TCMBANKGE000324 | BTK | AGMX1; AT; ATK; BPK; IGHD3; IMD1; PSCTK1; XLA | Bruton tyrosine kinase |
| TCMBANKGE000818 | ROS1 | MCF3; ROS; c-ros-1 | ROS proto-oncogene 1, receptor tyrosine kinase |
| TCMBANKGE002833 | MED12 | ARC240; CAGH45; FGS1; HOPA; Kto; MED12S; OHDOX; OKS; OPA1; TNRC11; TRAP230 | mediator complex subunit 12 |
| TCMBANKGE000464 | TRIM13 | CAR; DLEU5; LEU5; RFP2; RNF77 | tripartite motif containing 13 |
| TCMBANKGE000937 | PAX5 | ALL3; BSAP | paired box 5 |
| TCMBANKGE000635 | AURKA | AIK; ARK1; AURA; BTAK; PPP1R47; STK15; STK6; STK7 | aurora kinase A |
| TCMBANKGE000685 | ABL1 | ABL; BCR-ABL; CHDSKM; JTK7; bcr/abl; c-ABL; c-ABL1; p150; v-abl | ABL proto-oncogene 1, non-receptor tyrosine kinase |
| TCMBANKGE000047 | AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | AKT serine/threonine kinase 1 |
| TCMBANKGE007959 | PTPN12 | PTP-PEST; PTPG1 | protein tyrosine phosphatase non-receptor type 12 |
| TCMBANKGE010712 | MME | CALLA; CD10; CMT2T; NEP; SCA43; SFE | membrane metalloendopeptidase |
| TCMBANKGE000960 | STAT5A | MGF; STAT5 | signal transducer and activator of transcription 5A |
| TCMBANKGE000457 | CXADR | CAR; CAR4/6; HCAR | CXADR Ig-like cell adhesion molecule |
| TCMBANKGE000477 | EZH2 | ENX-1; ENX1; EZH2b; KMT6; KMT6A; WVS; WVS2 | enhancer of zeste 2 polycomb repressive complex 2 subunit |
| TCMBANKGE002022 | XRCC1 | RCC; SCAR26 | X-ray repair cross complementing 1 |
| TCMBANKGE000462 | ARR3 | ARRX; MYP26; cArr | arrestin 3 |
| TCMBANKGE000825 | CDKN1B | CDKN4; KIP1; MEN1B; MEN4; P27KIP1 | cyclin dependent kinase inhibitor 1B |
| TCMBANKGE001126 | NFE2L2 | HEBP1; IMDDHH; NRF2; Nrf-2 | nuclear factor, erythroid 2 like 2 |
| TCMBANKGE010442 | SETD2 | HBP231; HIF-1; HIP-1; HSPC069; HYPB; KMT3A; LLS; SET2; p231HBP | SET domain containing 2, histone lysine methyltransferase |
| TCMBANKGE005226 | LDHA | GSD11; HEL-S-133P; LDHM; PIG19 | lactate dehydrogenase A |
| TCMBANKGE000898 | MYC | MRTL; MYCC; bHLHe39; c-Myc | MYC proto-oncogene, bHLH transcription factor |
| TCMBANKGE001097 | HIF1A | HIF-1-alpha; HIF-1A; HIF-1alpha; HIF1; HIF1-ALPHA; MOP1; PASD8; bHLHe78 | hypoxia inducible factor 1 subunit alpha |
| TCMBANKGE000999 | FOXM1 | FKHL16; FOXM1A; FOXM1B; FOXM1C; HFH-11; HFH11; HNF-3; INS-1; MPHOSPH2; MPP-2; MPP2; PIG29; TRIDENT | forkhead box M1 |
| TCMBANKGE007038 | SDS | SDH | serine dehydratase |
| TCMBANKGE001073 | PTGS2 | COX-2; COX2; GRIPGHS; PGG/HS; PGHS-2; PHS-2; hCox-2 | prostaglandin-endoperoxide synthase 2 |
| TCMBANKGE002600 | FUS | ALS6; ETM4; FUS1; HNRNPP2; POMP75; TLS | FUS RNA binding protein |
| TCMBANKGE002052 | CIB1 | CIB; CIBP; KIP1; PRKDCIP; SIP2-28 | calcium and integrin binding 1 |
| TCMBANKGE000652 | STAT5B | STAT5 | signal transducer and activator of transcription 5B |
| TCMBANKGE007487 | VHL | HRCA1; RCA1; VHL1; pVHL | von Hippel-Lindau tumor suppressor |
| TCMBANKGE000823 | GABPA | E4TF1-60; E4TF1A; NFT2; NRF2; NRF2A; RCH04A07 | GA binding protein transcription factor subunit alpha |
| TCMBANKGE000465 | CASR | CAR; EIG8; FHH; FIH; GPRC2A; HHC; HHC1; HYPOC1; NSHPT; PCAR1; hCasR | calcium sensing receptor |
| TCMBANKGE012203 | FH | FMRD; HLRCC; HsFH; LRCC; MCL; MCUL1 | fumarate hydratase |
| TCMBANKGE000109 | ACTB | BRWS1; PS1TP5BP1 | actin beta |
| TCMBANKGE000806 | HSPA4 | APG-2; HEL-S-5a; HS24/P52; HSPH2; RY; hsp70; hsp70RY | heat shock protein family A (Hsp70) member 4 |
| TCMBANKGE009874 | CDKN2B | CDK4I; INK4B; MTS2; P15; TP15; p15INK4b | cyclin dependent kinase inhibitor 2B |
| TCMBANKGE009543 | LTA | LT; TNFB; TNFSF1; TNLG1E | lymphotoxin alpha |
| TCMBANKGE010948 | SARDH | BPR-2; DMGDHL1; SAR; SARD; SDH | sarcosine dehydrogenase |
| TCMBANKGE000219 | CCR5 | CC-CKR-5; CCCKR5; CCR-5; CD195; CKR-5; CKR5; CMKBR5; IDDM22 | C-C motif chemokine receptor 5 |
| TCMBANKGE000637 | SDHB | CWS2; IP; PGL4; SDH; SDH1; SDH2; SDHIP | succinate dehydrogenase complex iron sulfur subunit B |
| TCMBANKGE001045 | CCND1 | BCL1; D11S287E; PRAD1; U21B31 | cyclin D1 |
| TCMBANKGE000930 | ACLY | ACL; ATPCL; CLATP | ATP citrate lyase |
| TCMBANKGE001172 | HSP90AA1 | EL52; HEL-S-65p; HSP86; HSP89A; HSP90A; HSP90N; HSPC1; HSPCA; HSPCAL1; HSPCAL4; HSPN; Hsp103; Hsp89; Hsp90; LAP-2; LAP2 | heat shock protein 90 alpha family class A member 1 |
| TCMBANKGE000456 | CXADRP1 | CAR; CXADRP | CXADR pseudogene 1 |
| TCMBANKGE000874 | AURKB | AIK2; AIM-1; AIM1; ARK-2; ARK2; AurB; IPL1; PPP1R48; STK-1; STK12; STK5; aurkb-sv1; aurkb-sv2 | aurora kinase B |
| TCMBANKGE011776 | EIF4E | AUTS19; CBP; EIF4E1; EIF4EL1; EIF4F; eIF-4E | eukaryotic translation initiation factor 4E |
| TCMBANKGE003865 | SORD | HEL-S-95n; RDH; SDH; SORD1; XDH | sorbitol dehydrogenase |
| TCMBANKGE000459 | PRKAR1A | ACRDYS1; ADOHR; CAR; CNC; CNC1; PKR1; PPNAD1; PRKAR1; TSE1 | protein kinase cAMP-dependent type I regulatory subunit alpha |
| TCMBANKGE002526 | BAP1 | HUCEP-13; UCHL2; hucep-6 | BRCA1 associated protein 1 |
| TCMBANKGE000008 | CD40 | Bp50; CDW40; TNFRSF5; p50 | CD40 molecule |
| TCMBANKGE000463 | SPG7 | CAR; CMAR; PGN; SPG5C | SPG7 matrix AAA peptidase subunit, paraplegin |
| TCMBANKGE002626 | SPIB | SPI-B | Spi-B transcription factor |
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Dai SX Lab