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靶点ID:TCMBANKGE012203
靶点别名:FMRD; HLRCC; HsFH; LRCC; MCL; MCUL1
靶点描述:fumarate hydratase
染色体:1
染色体位置:1q43
靶点类型:protein-coding
HERB_ID:HBTAR001389
HGNC_Link:3700
OMIM_Link:136850
Ensembl_Link:ENSG00000091483
靶点对应的植物
| ID | 拉丁名 | 药名 | 药用植物名 | 功能与主治 | 来源 | 药用部位 | 使用民族 |
|---|
靶点对应的化合物
| 化合物ID | 化合物名 | 别名 | 分子式 | 分子质量 | Smiles |
|---|
| TCMBANKIN012700 | coumestrol | NCIMech_000078; CCRIS 7311; A-Lactone; API0002121; Tox21_200032; MolPort-003-846-031; US8552057, 3; HMS3374A07; 3,9-Dihydroxy-6H-benzofuro[3,2-c]-[1]benzopyran-6-one; 6H-Benzofuro[3,2-c][1]benzopyran-6-one,3,9-dihydroxy-; Cumostrol; CHEBI:3908; C-16836; VZ31590; LS-35394; S00280; 3,9-dihydroxy-[1]benzofuro[3,2-c]chromen-6-one; MFCD00016885; SMP2_000163; DSSTox_RID_76572; 27885_FLUKA; 6H-Benzofuro[3, 3,9-dihydroxy-; 5-19-06-00405 (Beilstein Handbook Reference); BRN 0266702; 479-13-0; NSC22842; 3-Benzofurancarboxylic acid, 2-(2,4-dihydroxyphenyl)-6-hydroxy-, delta-lactone; C10205; 3,9-dihydroxy-[1]benzoxolo[3,2-c]chromen-6-one; AC1NQYXV; 3-Benzofurancarboxylic acid, 2-(2,4-dihydroxyphenyl)-6-hydroxy-, delta-lactone (6CI); NCGC00018124-01; DSSTox_CID_2399; CTK8F8799; Coumestrol, >=95.0% (HPLC); NCI60_001863; 4CN-2508; ZZIALNLLNHEQPJ-UHFFFAOYSA-N; BIDD:ER0114; NCGC00018124-03; 3,9-Dihydroxy-6H-[1]benzofuro[3,2-c]chromen-6-one #; 6H-Benzofuro(3,2-c)(1)benzopyran-6-one, 3,9-dihydroxy-; A1-00298; NSC 22842; 3,9-Dihydroxy-6H-benzofuro(3,2-c)(1)benzopyran-6-one; CCG-35536; NCGC00018124-06; 3,9-bis(oxidanyl)-[1]benzofuro[3,2-c]chromen-6-one; ZINC1219; NCGC00257586-01; 3,9-Dihydroxy-benzo[4,5]furo[3,2-c]chromen-6-one; AIDS011954; SCHEMBL22012; UNII-V7NW98OB34; 3-Benzofurancarboxylic acid, 2-(2,4-dihydroxyphenyl)-6-hydroxy-, .delta.-lactone; 6H-Benzofuro[3,2-c][1]benzopyran-6-one, 3,9-dihydroxy-; MLS000069446; CCG-36200; LMPK12090018; 3-Benzofurancarboxylic acid,4-dihydroxyphenyl)-6-hydroxy-, .delta.-lactone; 7,12-Dihydroxycoumestan; CS-6343; D02DML; CHEMBL30707; 3,9-dihydroxy-6-benzofurano[3,2-c]chromenone; ZINC00001219; 5,14-dihydroxy-8,17-dioxatetracyclo[8.7.0.0^{2,7}.0^{11,16}]heptadeca-1(10),2,4,6,11(16),12,14-heptaen-9-one; Oprea1_222511; MLS000738006; EINECS 207-525-6; 3,9-Dihydroxycoumestan; Coumestrol, BioReagent, suitable for fluorescence, >=97.5% (HPLC); A827386; DTXSID6022399; CAS-479-13-0; FT-0603177; ST50320052; 2-(2,4-Dihydroxyphenyl)-6-hydroxy-3-benzofurancarboxylic Acid ; 3,9-dihydroxybenzofurano[3,2-c]chromen-6-one; 3,9-dihydroxybenzo[d]chromeno[4,3-b]furan-6-one; NCGC00023462-03; AIDS-011954; V0359; Cumoestrol; DSSTox_GSID_22399; Cumoesterol; NCGC00018124-05; Coumestrol; NCGC00018124-04; V7NW98OB34; ZB000278; 3,9-Dihydroxy-6H-[1]benzofuro[3,2-c]chromen-6-one; ST5320052; AN-6463; Cumestrol; NCGC00023462-04; NCGC00018124-02; CC-25990; 6H-Benzofuro(3,2-c)(1)benzopyran-6-one, 3,9-dihdyroxy-; NSC-22842; 3,9-dihydroxybenzofuro[3,2-c]chromen-6-one; AKOS028111776; HMS2235B05; Coumesterol; COUMESTROL; BDBM23451; SMR000059001; HY-N2335; 27883_FLUKA | C15H8O5 | 268.22 | C1=CC2=C(C=C1O)OC3=C2C(=O)OC4=C3C=CC(=C4)O |
| TCMBANKIN033702 | citric acid | InChI=1/C6H8O7/c7-3(8)1-6(13,5(11)12)2-4(9)10/h13H,1-2H2,(H,7,8)(H,9,10)(H,11,12; NCGC00090954-02; NCGC00090954-01; HSDB 911; CIT; Citric acid (8CI); BRN 0782061; NCIStruc2_000099; 27109_RIEDEL; AIDS-017733; 1,2,3-PROPANETRICARBOXYLIC ACID,2-HYDROXY (CITRIC ACID); citr; 27488_FLUKA; FEMA No. 2306; E 330; 27485_FLUKA; 27487_FLUKA; 77-92-9; C2404_SIGMA; 2-Hydroxytricarballylic acid; NCIOpen2_004502; F 0001 (polycarboxylic acid); EPA Pesticide Chemical Code 021801; AI3-06286; 245654-34-6; 1,2,3-Propanetricarboxylic acid, 2-hydroxy-; Citretten; Kyselina citronova; 2-hydroxypropane-1,2,3-tricarboxylic acid; Anhydrous citric acid; Citrate standard for IC; C83155_SIAL; LS-2418; WLN: QV1XQVQ1VQ; 1,2,3-Propanetricarboxylic acid, 2-hydroxy- (9CI); NSC30279; .beta.-Hydroxytricarballylic acid; NSC 626579; FLC; NCI60_022579; LS-3185; 2-hydroxy-1,2,3-propanetricarboxylic acid; Caswell No. 221C; EINECS 201-069-1; 43136-35-2; 251275_SIAL; 38730_FLUKA; C4540_SIGMA; FEMA Number 2306; 4-03-00-01272 (Beilstein Handbook Reference); 3-Carboxy-3-hydroxypentane-1,5-dioic acid; Citric acid anhydrous (JAN); C00158; 12262-73-6; 240621_ALDRICH; AIDS017733; MLS001066346; Kyselina 2-hydroxy-1,2,3-propantrikarbonova [Czech]; 2-Hydroxypropanetricarboxylic acid; CCRIS 3292; KBio3_002740; NSC626579; D00037; SBB008922; Kyselina citronova [Czech]; Aciletten; NSC 30279; Anhydrous citric acid (JP15); 46933_SUPELCO; NCIOpen2_004062; Citric acid solution; CHEBI:30769; Citro; BSPBio_003240; NCIStruc1_000057; Uro-trainer; Citric acid, anhydrous (USP); W230618_ALDRICH; Citric acid [USAN:JAN]; H3cit; Chemfill; Hydrocerol A; Suby G; Oprea1_502996; Citric acid, anhydrous; SMR000471840; Citric acid anhydrous; Spectrum3_001850 | C6H8O7 | 192.12 | C(C(=O)O)C(CC(=O)O)(C(=O)O)O |
| TCMBANKIN057931 | DMR | CHEBI:30796; 02300_FLUKA; Malic acid, L(+)-; L(+)-Malic acid; C00497; InChI=1/C4H6O5/c5-2(4(8)9)1-3(6)7/h2,5H,1H2,(H,6,7)(H,8,9; butanedioic acid, 2-hydroxy-; (R)-()-2-Hydroxysuccinic acid; (2R)-2-hydroxysuccinic acid; D-()-Malic acid; D-Hydroxybutanedioic acid; EINECS 211-262-2; (R)-malic acid; Malic acid D-(+)-form; 2-HYDROXY-SUCCINIC ACID; MLS000069520; (2R)-2-hydroxybutanedioic acid; 46940U_SUPELCO; SMR000058580; (+)-D-malic acid; Malic acid, D-; R-malic acid; D- malic acid | C4H6O5 | 134.09 g/mol | C(C(C(=O)O)O)C(=O)O |
| TCMBANKIN058311 | pinosylvin | (trans)-3,5-stilbenediol; LS-146810; W2082; 5-[(E)-2-PHENYLETHENYL]-1,3-BENZENEDIOL; 5-[(E)-2-phenylvinyl]benzene-1,3-diol; 3,5-Dihydroxystilbene; NSC-362430; BRN 1870942; 1,3-Benzenediol,5-[(1E)-2-phenylethenyl]-; ZINC901115; A815968; PubChem19089; AC-7928; MolPort-000-880-993; UNII-75IT683K8W component YCVPRTHEGLPYPB-VOTSOKGWSA-N; trans-pinosylvin; 1,3-Benzenediol, 5-(2-phenylethenyl)-, (E)-; D33B05BD-8441-4288-A247-D461C3D1F1CA; 5-(2-phenylethenyl)benzene-1,3-diol; LMPK13090001; NSC362430; NSC 362430; AKOS000276828; 22139-77-1; AK162490; 5-[(1E)-2-phenylethenyl]benzene-1,3-diol; SDCCGMLS-0066433.P001; BC657151; I14-6890; 5-[(E)-styryl]benzene-1,3-diol; 102-61-4; (E)-5-(2-Phenylethenyl)-1,3-benzenediol; 1,3-Benzenediol, 5-(2-phenylethenyl)-; NCGC00179033-01; 5-[(E)-2-phenylethenyl]benzene-1,3-diol; 5-(2-phenylvinyl)benzene-1,3-diol; C01745; pound inverted question markPinosylvin; Pinosylvin; CCG-38399; 5-(2-phenylethenyl)-1,3-benzenediol; AX8015298; BSPBio_001753; 3,5-stilbenediol; 5-Styrylresorcinol; AC1NQX1Y; Pinosylvin, >=97.0% (HPLC); (E)-5-Styrylbenzene-1,3-diol; 3-06-00-05577 (Beilstein Handbook Reference); UNII-881R434AIB; SC-20584; Stilbene, 3,5-dihydroxy-, trans-; Pinosylvine; (E)-3,5-stilbenediol; Stilbene, 1f; BDBM50045924; Spectrum5_000307; 1,3-Benzenediol, 5-[(1E)-2-phenylethenyl]-; MolPort-044-723-416; 881R434AIB; 139P771; ZB015246; SCHEMBL454262; 3,5-dihydroxy-trans-stilbene; 3,5-Stilbenediol, (E)-; CHEBI:17323; ST51054405; trans-3,5-Dihydroxystilbene; BRD-K94645280-001-02-1; (E)-pinosylvin; AC1Q7AYY; ST24035072; CHEBI:36011; CHEMBL101506;3,5-dihydroxystilbene | C14H12O2 | 212.24 g/mol | C1=CC=C(C=C1)C=CC2=CC(=CC(=C2)O)O |
靶点对应的疾病
| 疾病ID | 疾病名 | MeSH名 | HPO名 | UMLS名 | 疾病类型 |
|---|
| TCMBANKDI000023 | Skin and Connective Tissue Diseases; Immune System Diseases | Abnormality of the immune system | Disease or Syndrome | disease | |
| TCMBANKDI000035 | Digestive System Diseases; Infections | - | Disease or Syndrome | disease | |
| TCMBANKDI000802 | Pathological Conditions, Signs and Symptoms; Skin and Connective Tissue Diseases | Abnormality of the integument | Finding | phenotype | |
| TCMBANKDI001299 | Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Cardiovascular Diseases | Abnormality of the genitourinary system | Disease or Syndrome | disease | |
| TCMBANKDI002213 | Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases | Abnormality of metabolism/homeostasis; Abnormality of the genitourinary system | Disease or Syndrome | disease | |
| TCMBANKDI002231 | Digestive System Diseases | Abnormality of the digestive system | Disease or Syndrome | disease | |
| TCMBANKDI002297 | Infections | - | Disease or Syndrome | disease | |
| TCMBANKDI002512 | Digestive System Diseases | Abnormality of the digestive system; Abnormality of the immune system | Disease or Syndrome | disease | |
| TCMBANKDI002730 | Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Skin and Connective Tissue Diseases | Abnormality of the integument; Neoplasm | Neoplastic Process | disease | |
| TCMBANKDI002791 | Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases | Abnormality of the nervous system | Congenital Abnormality | disease | |
| TCMBANKDI003353 | Pathological Conditions, Signs and Symptoms; Neoplasms | - | Neoplastic Process | phenotype | |
| TCMBANKDI003411 | - | - | Disease or Syndrome | disease | |
| TCMBANKDI003585 | - | Abnormality of the endocrine system | Finding | phenotype | |
| TCMBANKDI003733 | Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Cardiovascular Diseases | Abnormality of the nervous system; Abnormality of blood and blood-forming tissues; Abnormality of the cardiovascular system | Pathologic Function | phenotype | |
| TCMBANKDI004280 | - | Abnormality of the nervous system | Finding | phenotype | |
| TCMBANKDI004450 | - | Abnormality of metabolism/homeostasis; Abnormal cellular phenotype | Anatomical Abnormality | disease | |
| TCMBANKDI004587 | Endocrine System Diseases | - | Disease or Syndrome | disease | |
| TCMBANKDI005528 | Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Nervous System Diseases | - | Congenital Abnormality | disease | |
| TCMBANKDI006060 | Pathological Conditions, Signs and Symptoms | Abnormality of the nervous system | Sign or Symptom | phenotype | |
| TCMBANKDI006612 | Neoplasms; Female Urogenital Diseases and Pregnancy Complications | Abnormality of the genitourinary system; Neoplasm | Neoplastic Process | disease | |
| TCMBANKDI007495 | - | Abnormality of metabolism/homeostasis; Abnormality of the genitourinary system | Finding | phenotype | |
| TCMBANKDI009231 | Pathological Conditions, Signs and Symptoms; Infections | Abnormality of the immune system | Disease or Syndrome | disease | |
| TCMBANKDI009853 | Neoplasms | Neoplasm; Abnormality of the cardiovascular system | Finding | phenotype | |
| TCMBANKDI011401 | Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Otorhinolaryngologic Diseases | Abnormality of the ear | Sign or Symptom | phenotype | |
| TCMBANKDI012126 | Eye Diseases; Cardiovascular Diseases | Abnormality of the eye; Abnormality of the cardiovascular system | Disease or Syndrome | disease | |
| TCMBANKDI013278 | Infections; Skin and Connective Tissue Diseases | - | Disease or Syndrome | disease | |
| TCMBANKDI013453 | Pathological Conditions, Signs and Symptoms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases | Abnormality of metabolism/homeostasis; Abnormality of the genitourinary system | Finding | phenotype | |
| TCMBANKDI013623 | Neoplasms | Abnormality of the endocrine system; Abnormality of the nervous system; Neoplasm | Neoplastic Process | disease | |
| TCMBANKDI015485 | Mental Disorders | Abnormality of the nervous system | Mental or Behavioral Dysfunction | disease | |
| TCMBANKDI015491 | Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Musculoskeletal Diseases; Nervous System Diseases; Cardiovascular Diseases | - | Disease or Syndrome | disease | |
| TCMBANKDI016800 | Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases | - | Neoplastic Process | disease | |
| TCMBANKDI017581 | - | - | Finding | phenotype | |
| TCMBANKDI017681 | Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Nervous System Diseases | Abnormality of head or neck; Abnormality of the skeletal system | Congenital Abnormality | disease | |
| TCMBANKDI017899 | Neoplasms; Cardiovascular Diseases | Abnormality of the nervous system; Neoplasm; Abnormality of head or neck; Abnormality of the eye; Abnormality of the cardiovascular system | Neoplastic Process | disease | |
| TCMBANKDI019267 | Pathological Conditions, Signs and Symptoms; Nervous System Diseases | Abnormality of the nervous system | Sign or Symptom | phenotype | |
| TCMBANKDI019465 | Neoplasms; Male Urogenital Diseases; Endocrine System Diseases | Abnormality of the genitourinary system; Neoplasm | Neoplastic Process | group | |
| TCMBANKDI020794 | Nutritional and Metabolic Diseases | Abnormality of metabolism/homeostasis | Disease or Syndrome | disease | |
| TCMBANKDI021382 | Pathological Conditions, Signs and Symptoms | Abnormality of the integument | Finding | phenotype | |
| TCMBANKDI021600 | Neoplasms | - | Neoplastic Process | disease | |
| TCMBANKDI023140 | Neoplasms; Endocrine System Diseases | Abnormality of the endocrine system; Neoplasm | Neoplastic Process | disease | |
| TCMBANKDI023336 | Neoplasms | Abnormality of the endocrine system; Abnormality of the nervous system; Neoplasm | Neoplastic Process | disease | |
| TCMBANKDI023751 | Pathological Conditions, Signs and Symptoms; Nervous System Diseases | Abnormality of the musculature | Finding | phenotype | |
| TCMBANKDI024035 | Neoplasms | Neoplasm | Neoplastic Process | disease | |
| TCMBANKDI025113 | Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases | Abnormality of the eye | Congenital Abnormality | disease | |
| TCMBANKDI025420 | Digestive System Diseases; Neoplasms | Abnormality of the digestive system; Neoplasm | Neoplastic Process | disease | |
| TCMBANKDI025465 | - | Abnormality of metabolism/homeostasis | Finding | phenotype | |
| TCMBANKDI025708 | - | Abnormality of metabolism/homeostasis; Abnormality of the genitourinary system | Finding | phenotype | |
| TCMBANKDI027961 | Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases | Abnormality of the nervous system | Congenital Abnormality | disease | |
| TCMBANKDI028701 | Pathological Conditions, Signs and Symptoms | Growth abnormality | Finding | phenotype | |
| TCMBANKDI029551 | Neoplasms | - | Neoplastic Process | disease | |
| TCMBANKDI029899 | Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases | Neoplasm; Abnormality of blood and blood-forming tissues | Neoplastic Process | group | |
| TCMBANKDI031114 | Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases | - | Disease or Syndrome | disease | |
| TCMBANKDI031570 | - | Abnormality of the nervous system | Mental or Behavioral Dysfunction | disease |
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