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TCMBANKDI015898

疾病ID:TCMBANKDI015898

疾病名:Glucose Metabolism Disorders

MeSH_Name:Nutritional and Metabolic Diseases

HPO_Name:-

UMLS_Name:Disease or Syndrome

DO_Name:disease of metabolism

疾病类型:group

DisGeNET_Link:C1257958

MeSH_Link:C18

HPO_Link:-

UMLS_Link:T047

DO_Link:DOID:0014667

HERB_ID:HBDIS012819

疾病对应的植物

ID	拉丁名	药名	药用植物名	功能与主治	来源	药用部位	使用民族

疾病对应的化合物

化合物ID	化合物名	别名	分子式	分子质量	Smiles

TCMBANKIN061511	arctigenin	AIDS002466; C10545; (3R,4R)-4-[(3,4-dimethoxyphenyl)methyl]-3-[(4-hydroxy-3-methoxy-phenyl)methyl]tetrahydrofuran-2-one; arctigenin ; Arctigenin; 41328-87-4; MLS002473154; NCGC00025291-01; MEGxp0_001799; HMS2198I14; Arctigenin, (+)-; (3S,4S)-4-[(3,4-dimethoxyphenyl)methyl]-3-[(4-hydroxy-3-methoxyphenyl)methyl]oxolan-2-one; 695QU32V04; SMR001397246; (3R,4R)-4-[(3,4-dimethoxyphenyl)methyl]-3-[(4-hydroxy-3-methoxyphenyl)methyl]oxolan-2-one; (3R,4R)-4-(3,4-dimethoxybenzyl)-3-(4-hydroxy-3-methoxy-benzyl)tetrahydrofuran-2-one; 7770-78-7; 26687-78-5; (3R,4R)-4-[(3,4-Dimethoxyphenyl)methyl]dihydro-3-[(4-hydroxy-3-methoxyphenyl)methyl]-2(3H)-furanone; AIDS-002466; ACon1_000416; Tocris-1777; (−)-Arctigenin; DTXSID50233381; UNII-2FD8L150E7 component NQWVSMVXKMHKTF-CVEARBPZSA-N; 2(3H)-Furanone, 4-((3,4-dimethoxyphenyl)methyl)dihydro-3-((4-hydroxy-3-methoxyphenyl)methyl)-, (3R-trans)-; (3R,4R)-4-[(3,4-dimethoxyphenyl)methyl]-3-[(4-hydroxy-3-methoxyphenyl)methyl]-2-tetrahydrofuranone; (-)-Arctigenin; UNII-695QU32V04; 2(3H)-Furanone, 4-((3,4-dimethoxyphenyl)methyl)dihydro-3-((4-hydroxy-3-methoxyphenyl)methyl)-, (3S-trans)-; A1854_SIGMA; Arctigenen; 84413-77-4; Arctigenin, trans-(+)-; (3R,4R)-4-[(3,4-dimethoxyphenyl)methyl]-3-[(4-hydroxy-3-methoxy-phenyl)methyl]oxolan-2-one; (+)-Arctigenin; 2(3H)-Furanone, 4-((3,4-dimethoxyphenyl)methyl)dihydro-3-((4-hydroxy-3-methoxyphenyl)methyl)-, (3S,4S)-; ZINC899931; 2(3H)-Furanone, 4-((3,4-dimethoxyphenyl)methyl)dihydro-3-((4-hydroxy-3-methoxyphenyl)methyl)-, (3R,4R)-; CHEMBL369142; (-)-arctigenin	C21H24O6	372.4 g/mol	COC1=C(C=C(C=C1)CC2COC(=O)C2CC3=CC(=C(C=C3)O)OC)OC

疾病对应的靶点

靶点ID	基因名	基因别名	描述

TCMBANKGE014832	DHCR24	DCE; Nbla03646; SELADIN1; seladin-1	24-dehydrocholesterol reductase
TCMBANKGE000452	CFTR	ABC35; ABCC7; CF; CFTR/MRP; MRP7; TNR-CFTR; dJ760C5.1	CF transmembrane conductance regulator
TCMBANKGE004036	ACSL1	ACS1; FACL1; FACL2; LACS; LACS1; LACS2	acyl-CoA synthetase long chain family member 1
TCMBANKGE014769	POSTN	OSF-2; OSF2; PDLPOSTN; PN	periostin
TCMBANKGE000168	NR3C1	GCCR; GCR; GCRST; GR; GRL	nuclear receptor subfamily 3 group C member 1
TCMBANKGE000226	UCP2	BMIQ4; SLC25A8; UCPH	uncoupling protein 2
TCMBANKGE001126	NFE2L2	HEBP1; IMDDHH; NRF2; Nrf-2	nuclear factor, erythroid 2 like 2
TCMBANKGE001178	STAT3	ADMIO; ADMIO1; APRF; HIES	signal transducer and activator of transcription 3
TCMBANKGE000791	DUSP1	CL100; HVH1; MKP-1; MKP1; PTPN10	dual specificity phosphatase 1
TCMBANKGE009974	CLOCK	KAT13D; bHLHe8	clock circadian regulator
TCMBANKGE001141	PPARA	NR1C1; PPAR; PPARalpha; hPPAR	peroxisome proliferator activated receptor alpha
TCMBANKGE000750	NR4A1	GFRP1; HMR; N10; NAK-1; NGFIB; NP10; NUR77; TR3	nuclear receptor subfamily 4 group A member 1
TCMBANKGE000823	GABPA	E4TF1-60; E4TF1A; NFT2; NRF2; NRF2A; RCH04A07	GA binding protein transcription factor subunit alpha
TCMBANKGE010789	HNF1A	HNF-1A; HNF1; HNF4A; IDDM20; LFB1; MODY3; TCF-1; TCF1	HNF1 homeobox A
TCMBANKGE000471	POMC	ACTH; CLIP; LPH; MSH; NPP; OBAIRH; POC	proopiomelanocortin
TCMBANKGE000956	NR1H4	BAR; FXR; HRR-1; HRR1; PFIC5; RIP14	nuclear receptor subfamily 1 group H member 4
TCMBANKGE001129	ARNTL	BMAL1; BMAL1c; JAP3; MOP3; PASD3; TIC; bHLHe5	aryl hydrocarbon receptor nuclear translocator like
TCMBANKGE000997	GCG	GLP-1; GLP1; GLP2; GRPP	glucagon
TCMBANKGE000835	APP	AAA; ABETA; ABPP; AD1; APPI; CTFgamma; CVAP; PN-II; PN2; preA4	amyloid beta precursor protein
TCMBANKGE000863	GPBAR1	BG37; GPCR19; GPR131; M-BAR; TGR5	G protein-coupled bile acid receptor 1
TCMBANKGE001185	PPARG	CIMT1; GLM1; NR1C3; PPARG1; PPARG2; PPARG5; PPARgamma	peroxisome proliferator activated receptor gamma
TCMBANKGE007089	HK1	HK; HK1-ta; HK1-tb; HK1-tc; HKD; HKI; HMSNR; HXK1; NEDVIBA; RP79; hexokinase	hexokinase 1
TCMBANKGE001125	IGF1	IGF; IGF-I; IGFI; MGF	insulin like growth factor 1
TCMBANKGE001134	IRS1	HIRS-1	insulin receptor substrate 1
TCMBANKGE000782	GCK	FGQTL3; GK; GLK; HHF3; HK4; HKIV; HXKP; LGLK; MODY2; PNDM1	glucokinase
TCMBANKGE000786	MIR200A	MIRN200A; mir-200a	microRNA 200a
TCMBANKGE005364	SLC2A2	GLUT2	solute carrier family 2 member 2
TCMBANKGE000514	CNR1	CANN6; CB-R; CB1; CB1A; CB1K5; CB1R; CNR	cannabinoid receptor 1
TCMBANKGE001085	MAPK8	JNK; JNK-46; JNK1; JNK1A2; JNK21B1/2; PRKM8; SAPK1; SAPK1c	mitogen-activated protein kinase 8
TCMBANKGE011684	TAS1R3	T1R3	taste 1 receptor member 3
TCMBANKGE000013	G6PC	G6PC1; G6PT; G6Pase; GSD1; GSD1a	glucose-6-phosphatase catalytic subunit