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疾病ID:TCMBANKDI018497

疾病名:Cicatrix, Hypertrophic

MeSH_Name:Pathological Conditions, Signs and Symptoms

HPO_Name:-

UMLS_Name:Acquired Abnormality

DO_Name:-

疾病类型:disease

DisGeNET_Link:C0162810

MeSH_Link:C23

HPO_Link:-

UMLS_Link:T020

DO_Link:-

HERB_ID:-

   疾病对应的植物
ID 拉丁名 药名 药用植物名 功能与主治 来源 药用部位 使用民族
   疾病对应的化合物
化合物ID 化合物名 别名 分子式 分子质量 Smiles
TCMBANKIN058752 shikonin HMS1990P11; 517-89-5; ST2402660; SBB066976; BSPBio_001270; AJ-32590; NEZONWMXZKDMKF-SNVBAGLBSA-N; N1643; (+)-Shikonin; HY-N0822; DTXSID30199653; NCGC00163489-01; 517S895; MLS006010149; CS-5906; 5,8-dihydroxy-2-[(1R)-1-hydroxy-4-methylpent-3-enyl]naphthalene-1,4-dione; HMS1792P11; AB0013814; RL03907; SR-05000001466-3; (R)-(+)-Shikonin; 1,4-NAPHTHOQUINONE, 5,8-DIHYDROXY-2-(1-HYDROXY-4-METHYL-3-PENTENYL)-, (+)-; BP-30212; J-502235; NSC 252844; SR-05000001466-1; s8279; HSDB 8100; CCG-208272; C17412; SCHEMBL33969; FT-0651798; CCRIS 6492; 874325-10-7; 3IK6592UBW; AC-26871; 5,8-Dihydroxy-2-[(1R)-1-hydroxy-4-methyl-pent-3-enyl]naphthalene-1,4-dione; HMS3403P11; BRN 2058010; KB-210224; AK105374; CHEBI:81068; CTK4J4851; NCGC00163489-02; NCGC00163489-04; N2643; KS-00001FJP; AC1LA0SH; 1,4-Naphthalenedione, 5,8-dihydroxy-2-(1-hydroxy-4-methyl-3-pentenyl)-, (R)-; 5,8-dihydroxy-2-[(1r)-1-hydroxy-4-methylpent-3-en-1-yl]-1,4-naphthoquinone; TR-031448; Shikonin S; AC1Q6B9B; 1,4-Naphthalenedione, 5,8-dihydroxy-2-[(1R)-1-hydroxy-4-methyl-3-pentenyl]-; ANW-73225; Tokyo Violet; MolPort-005-932-876; Shikonine; UNII-3IK6592UBW; W-2767; 876010-87-6; CJ-31254; (+)-5,8-Dihydroxy-2-(1-hydroxy-4-methyl-3-pentenyl)-1,4-naphthoquinone; 5,8-dihydroxy-2-[(1R)-1-hydroxy-4-methylpent-3-en-1-yl]-1,4-dihydronaphthalene-1,4-dione; SR-05000001466; 1,4-Naphthalenedione,5,8-dihydroxy-2-[(1R)-1-hydroxy-4-methyl-3-penten-1-yl]-; (R)-5,8-Dihydroxy-2-(1-hydroxy-4-methylpent-3-en-1-yl)naphthalene-1,4-dione; MFCD00075680; SMR002530673; AKOS015900416; AS-13554; ZINC2015152; (-)-Shikonin; BG01580835; I664; Isoarnebin 4; HMS2089L09; 5,8-dihydroxy-2-[(1R)-1-hydroxy-4-methylpent-3-enyl]naphthalene-1,4-dione; 5,8-Dihydroxy-2-((R)-1-hydroxy-4-methyl-pent-3-enyl)-[1,4]naphthoquinone; 5,8-dihydroxy-2-[(1R)-1-hydroxy-4-methyl-pent-3-enyl]naphthalene-1,4-dione; BSPBio_001270; AIDS094462; AIDS-094462; 5,8-dihydroxy-2-[(1R)-1-hydroxy-4-methyl-pent-3-enyl]-1,4-naphthoquinone; 1,4-Naphthalenedione, 5,8-dihydroxy-2-[(1R)-1-hydroxy-4-methyl-3-pentenyl]-; NCGC00163489-01; Isoarnebin 4 C16H16O5 288.3 CC(=CCC(C1=CC(=O)C2=C(C=CC(=C2C1=O)O)O)O)C
   疾病对应的靶点
靶点ID 基因名 基因别名 描述
TCMBANKGE001067 S100A8 60B8AG; CAGA; CFAG; CGLA; CP-10; L1Ag; MA387; MIF; MRP8; NIF; P8 S100 calcium binding protein A8
TCMBANKGE000973 EGF HOMG4; URG epidermal growth factor
TCMBANKGE011844 TRADD Hs.89862 TNFRSF1A associated via death domain
TCMBANKGE001180 SMAD3 HSPC193; HsT17436; JV15-2; LDS1C; LDS3; MADH3 SMAD family member 3
TCMBANKGE013782 LTBP2 C14orf141; GLC3D; LTBP3; MSPKA; MSTP031; WMS3 latent transforming growth factor beta binding protein 2
TCMBANKGE000137 PLAU ATF; BDPLT5; QPD; UPA; URK; u-PA plasminogen activator, urokinase
TCMBANKGE000583 MIR22 MIRN22; hsa-mir-22; miR-22 microRNA 22
TCMBANKGE000742 SMAD7 CRCS3; MADH7; MADH8 SMAD family member 7
TCMBANKGE007575 FKBP10 BRKS1; FKBP65; OI11; OI6; PPIASE; hFKBP65 FKBP prolyl isomerase 10
TCMBANKGE001213 S100A12 CAAF1; CAGC; CGRP; ENRAGE; MRP-6; MRP6; p6 S100 calcium binding protein A12
TCMBANKGE003095 F2RL1 GPR11; PAR2 F2R like trypsin receptor 1
TCMBANKGE000369 IFNA1 IFL; IFN; IFN-ALPHA; IFN-alphaD; IFNA13; IFNA@; leIF D interferon alpha 1
TCMBANKGE000162 MMP13 CLG3; MANDP1; MDST; MMP-13 matrix metallopeptidase 13
TCMBANKGE013010 COX2 COII; MTCO2 cytochrome c oxidase subunit II
TCMBANKGE012222 IFNA13 - interferon alpha 13
TCMBANKGE008312 CKAP4 CLIMP-63; CLIMP63; ERGIC-63; p63 cytoskeleton associated protein 4
TCMBANKGE000363 GEMIN2 SIP1; SIP1-delta gem nuclear organelle associated protein 2
TCMBANKGE006480 TNFAIP6 TSG-6; TSG6 TNF alpha induced protein 6
TCMBANKGE000871 IGFBP3 BP-53; IBP3 insulin like growth factor binding protein 3
TCMBANKGE002175 COL3A1 EDS4A; EDSVASC; PMGEDSV collagen type III alpha 1 chain
TCMBANKGE009229 MSC ABF-1; ABF1; MYOR; bHLHa22 musculin
TCMBANKGE000135 CXCR4 CD184; D2S201E; FB22; HM89; HSY3RR; LAP-3; LAP3; LCR1; LESTR; NPY3R; NPYR; NPYRL; NPYY3R; WHIM; WHIMS C-X-C motif chemokine receptor 4
TCMBANKGE005068 SLC12A9 CCC6; CIP1; WO3.3; hCCC6 solute carrier family 12 member 9
TCMBANKGE001133 PTK2 FADK; FAK; FAK1; FRNK; PPP1R71; p125FAK; pp125FAK protein tyrosine kinase 2
TCMBANKGE009133 GDF9 POF14 growth differentiation factor 9
TCMBANKGE008315 SLC9A3R2 E3KARP; NHE3RF2; NHERF-2; NHERF2; OCTS2; SIP-1; SIP1; TKA-1 SLC9A3 regulator 2
TCMBANKGE000047 AKT1 AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA AKT serine/threonine kinase 1
TCMBANKGE001074 ATM AT1; ATA; ATC; ATD; ATDC; ATE; TEL1; TELO1 ATM serine/threonine kinase
TCMBANKGE000294 CDKN1A CAP20; CDKN1; CIP1; MDA-6; P21; SDI1; WAF1; p21CIP1 cyclin dependent kinase inhibitor 1A
TCMBANKGE009024 SLC52A1 GPCR42; GPR172B; PAR2; RBFVD; RFT1; RFVT1; hRFT1; huPAR-2 solute carrier family 52 member 1
TCMBANKGE013160 LAMA1 LAMA; PTBHS; S-LAM-alpha laminin subunit alpha 1
TCMBANKGE000925 PCNA ATLD2 proliferating cell nuclear antigen
TCMBANKGE003113 CX3CL1 ABCD-3; C3Xkine; CXC3; CXC3C; NTN; NTT; SCYD1; fractalkine; neurotactin C-X3-C motif chemokine ligand 1
TCMBANKGE010656 PTPN5 PTPSTEP; STEP; STEP61 protein tyrosine phosphatase non-receptor type 5
TCMBANKGE004914 MDM4 BMFS6; HDMX; MDMX; MRP1 MDM4 regulator of p53
TCMBANKGE005777 AGTR2 AT2; ATGR2; MRX88 angiotensin II receptor type 2
TCMBANKGE014769 POSTN OSF-2; OSF2; PDLPOSTN; PN periostin
TCMBANKGE005933 LUM LDC; SLRR2D lumican
TCMBANKGE013655 SLC33A1 ACATN; AT-1; AT1; CCHLND; SPG42 solute carrier family 33 member 1
TCMBANKGE000305 PIK3CD APDS; IMD14; P110DELTA; PI3K; p110D phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
TCMBANKGE000633 ADRB2 ADRB2R; ADRBR; B2AR; BAR; BETA2AR adrenoceptor beta 2
TCMBANKGE001156 CASP3 CPP32; CPP32B; SCA-1 caspase 3
TCMBANKGE012642 COL18A1 GLCC; KNO; KNO1; KS collagen type XVIII alpha 1 chain
TCMBANKGE000882 SERPINE1 PAI; PAI-1; PAI1; PLANH1 serpin family E member 1
TCMBANKGE003300 EIF6 CAB; EIF3A; ITGB4BP; b(2)gcn; eIF-6; p27(BBP); p27BBP eukaryotic translation initiation factor 6
TCMBANKGE000282 ELN ADCL1; SVAS; WBS; WS elastin
TCMBANKGE007072 TGFB1I1 ARA55; HIC-5; HIC5; TSC-5 transforming growth factor beta 1 induced transcript 1
TCMBANKGE001179 SMAD2 JV18; JV18-1; MADH2; MADR2; hMAD-2; hSMAD2 SMAD family member 2
TCMBANKGE000364 SMN1 BCD541; GEMIN1; SMA; SMA1; SMA2; SMA3; SMA4; SMA@; SMN; SMNT; T-BCD541; TDRD16A survival of motor neuron 1, telomeric
TCMBANKGE004741 TPM3 CAPM1; CFTD; HEL-189; HEL-S-82p; NEM1; OK/SW-cl.5; TM-5; TM3; TM30; TM30nm; TM5; TPM3nu; TPMsk3; TRK; hscp30 tropomyosin 3
TCMBANKGE001086 SIRT7 SIR2L7 sirtuin 7
TCMBANKGE001107 NOS3 ECNOS; eNOS nitric oxide synthase 3
TCMBANKGE000929 MIR145 MIRN145; miR-145; miRNA145 microRNA 145
TCMBANKGE000331 CALCA CALC1; CGRP; CGRP-I; CGRP-alpha; CGRP1; CT; KC; PCT calcitonin related polypeptide alpha
TCMBANKGE001037 MMP2 CLG4; CLG4A; MMP-2; MMP-II; MONA; TBE-1 matrix metallopeptidase 2
TCMBANKGE001198 BECN1 ATG6; VPS30; beclin1 beclin 1
TCMBANKGE004297 SCAF11 CASP11; SFRS2IP; SIP1; SRRP129; SRSF2IP SR-related CTD associated factor 11
TCMBANKGE009300 THBS4 TSP-4; TSP4 thrombospondin 4
TCMBANKGE000078 BRD4 CAP; HUNK1; HUNKI; MCAP bromodomain containing 4
TCMBANKGE012729 CSAD CSD; PCAP cysteine sulfinic acid decarboxylase
TCMBANKGE000204 CXCL8 GCP-1; GCP1; IL8; LECT; LUCT; LYNAP; MDNCF; MONAP; NAF; NAP-1; NAP1; SCYB8 C-X-C motif chemokine ligand 8
TCMBANKGE012468 OSM - oncostatin M
TCMBANKGE000515 DIABLO DFNA64; SMAC diablo IAP-binding mitochondrial protein
TCMBANKGE000727 MAP1LC3A ATG8E; LC3; LC3A; MAP1ALC3; MAP1BLC3 microtubule associated protein 1 light chain 3 alpha
TCMBANKGE000479 TIMP1 CLGI; EPA; EPO; HCI; TIMP; TIMP-1 TIMP metallopeptidase inhibitor 1
TCMBANKGE011009 BMP7 OP-1 bone morphogenetic protein 7
TCMBANKGE001097 HIF1A HIF-1-alpha; HIF-1A; HIF-1alpha; HIF1; HIF1-ALPHA; MOP1; PASD8; bHLHe78 hypoxia inducible factor 1 subunit alpha
TCMBANKGE000537 ABCC1 ABC29; ABCC; GS-X; MRP; MRP1 ATP binding cassette subfamily C member 1
TCMBANKGE013948 TGFB3 ARVD; ARVD1; LDS5; RNHF; TGF-beta3 transforming growth factor beta 3
TCMBANKGE000318 HMGB1 HMG-1; HMG1; HMG3; SBP-1 high mobility group box 1
TCMBANKGE014851 TRPC3 SCA41; TRP3 transient receptor potential cation channel subfamily C member 3
TCMBANKGE014891 MMP19 CODA; MMP18; RASI-1 matrix metallopeptidase 19
TCMBANKGE004101 RPE65 BCO3; LCA2; RP20; mRPE65; p63; rd12; sRPE65 retinoid isomerohydrolase RPE65
TCMBANKGE001182 SIRT1 SIR2; SIR2L1; SIR2alpha sirtuin 1
TCMBANKGE000280 VIM - vimentin
TCMBANKGE001073 PTGS2 COX-2; COX2; GRIPGHS; PGG/HS; PGHS-2; PHS-2; hCox-2 prostaglandin-endoperoxide synthase 2
TCMBANKGE000224 AGT ANHU; SERPINA8; hFLT1 angiotensinogen
TCMBANKGE003565 TGFBR1 AAT5; ACVRLK4; ALK-5; ALK5; ESS1; LDS1; LDS1A; LDS2A; MSSE; SKR4; TBR-i; TBRI; TGFR-1; tbetaR-I transforming growth factor beta receptor 1
TCMBANKGE000706 ARG1 - arginase 1
TCMBANKGE007918 DDR1 CAK; CD167; DDR; EDDR1; HGK2; MCK10; NEP; NTRK4; PTK3; PTK3A; RTK6; TRKE discoidin domain receptor tyrosine kinase 1
TCMBANKGE000307 PIK3CB P110BETA; PI3K; PI3KBETA; PIK3C1 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
TCMBANKGE001007 NR1I2 BXR; ONR1; PAR; PAR1; PAR2; PARq; PRR; PXR; SAR; SXR nuclear receptor subfamily 1 group I member 2
TCMBANKGE004114 CDKN3 CDI1; CIP2; KAP; KAP1 cyclin dependent kinase inhibitor 3
TCMBANKGE010750 SFRP2 FRP-2; SARP1; SDF-5 secreted frizzled related protein 2
TCMBANKGE001088 SMAD4 DPC4; JIP; MADH4; MYHRS SMAD family member 4
TCMBANKGE014252 IL15 IL-15 interleukin 15
TCMBANKGE000273 LOX AAT10 lysyl oxidase
TCMBANKGE000394 CXCR3 CD182; CD183; CKR-L2; CMKAR3; GPR9; IP10-R; Mig-R; MigR C-X-C motif chemokine receptor 3
TCMBANKGE000222 EDN1 ARCND3; ET1; HDLCQ7; PPET1; QME endothelin 1
TCMBANKGE000822 ANXA5 ANX5; ENX2; HEL-S-7; PP4; RPRGL3 annexin A5
TCMBANKGE002445 GHRL MTLRP ghrelin and obestatin prepropeptide
TCMBANKGE005666 DCN CSCD; DSPG2; PG40; PGII; PGS2; SLRR1B decorin
TCMBANKGE001697 MMP1 CLG; CLGN matrix metallopeptidase 1
TCMBANKGE014962 COX8A COX; COX8; COX8-2; COX8L; VIII; VIII-L cytochrome c oxidase subunit 8A
TCMBANKGE006972 FGF13 FGF-13; FGF2; FHF-2; FHF2; LINC00889 fibroblast growth factor 13
TCMBANKGE011473 CCL13 CKb10; MCP-4; NCC-1; NCC1; SCYA13; SCYL1 C-C motif chemokine ligand 13
TCMBANKGE000388 ZEB1 AREB6; BZP; DELTAEF1; FECD6; NIL2A; PPCD3; TCF8; ZFHEP; ZFHX1A zinc finger E-box binding homeobox 1
TCMBANKGE001188 CXCL10 C7; IFI10; INP10; IP-10; SCYB10; crg-2; gIP-10; mob-1 C-X-C motif chemokine ligand 10
TCMBANKGE000471 POMC ACTH; CLIP; LPH; MSH; NPP; OBAIRH; POC proopiomelanocortin
TCMBANKGE001100 MIR155 MIRN155; miRNA155; mir-155 microRNA 155
TCMBANKGE000150 MIR192 MIRN192; miR-192; miRNA192 microRNA 192
TCMBANKGE007816 UVRAG DHTX; VPS38; p63 UV radiation resistance associated
TCMBANKGE011987 TP63 AIS; B(p51A); B(p51B); EEC3; KET; LMS; NBP; OFC8; RHS; SHFM4; TP53CP; TP53L; TP73L; p40; p51; p53CP; p63; p73H; p73L tumor protein p63
TCMBANKGE000610 CD1A CD1; FCB6; HTA1; R4; T6 CD1a molecule
TCMBANKGE012494 HAS1 HAS hyaluronan synthase 1
TCMBANKGE000109 ACTB BRWS1; PS1TP5BP1 actin beta
TCMBANKGE013400 COX5A COX; COX-VA; VA cytochrome c oxidase subunit 5A
TCMBANKGE000522 AGTR1 AG2S; AGTR1B; AT1; AT1AR; AT1B; AT1BR; AT1R; AT2R1; HAT1R angiotensin II receptor type 1
TCMBANKGE014693 ADRB3 BETA3AR adrenoceptor beta 3
TCMBANKGE000072 CXCL12 IRH; PBSF; SCYB12; SDF1; TLSF; TPAR1 C-X-C motif chemokine ligand 12
TCMBANKGE000668 ITGB1 CD29; FNRB; GPIIA; MDF2; MSK12; VLA-BETA; VLAB integrin subunit beta 1
TCMBANKGE003792 SLC25A32 MFT; MFTC; RREI solute carrier family 25 member 32
TCMBANKGE010598 WNT4 SERKAL; WNT-4 Wnt family member 4
TCMBANKGE006006 RAG2 RAG-2 recombination activating 2
TCMBANKGE008164 TGFBI BIGH3; CDB1; CDG2; CDGG1; CSD; CSD1; CSD2; CSD3; EBMD; LCD1 transforming growth factor beta induced
TCMBANKGE000251 FGF2 BFGF; FGF-2; FGFB; HBGF-2 fibroblast growth factor 2
TCMBANKGE000398 MIR137 MIRN137; miR-137 microRNA 137
TCMBANKGE002589 FBP1 FBP fructose-bisphosphatase 1
TCMBANKGE001185 PPARG CIMT1; GLM1; NR1C3; PPARG1; PPARG2; PPARG5; PPARgamma peroxisome proliferator activated receptor gamma
TCMBANKGE000240 IL17A CTLA-8; CTLA8; IL-17; IL-17A; IL17 interleukin 17A
TCMBANKGE000884 FN1 CIG; ED-B; FINC; FN; FNZ; GFND; GFND2; LETS; MSF; SMDCF fibronectin 1
TCMBANKGE001125 IGF1 IGF; IGF-I; IGFI; MGF insulin like growth factor 1
TCMBANKGE010583 SMN2 BCD541; C-BCD541; GEMIN1; SMNC; TDRD16B survival of motor neuron 2, centromeric
TCMBANKGE008893 TAT - tyrosine aminotransferase
TCMBANKGE001102 MIR21 MIRN21; hsa-mir-21; miR-21; miRNA21 microRNA 21
TCMBANKGE001045 CCND1 BCL1; D11S287E; PRAD1; U21B31 cyclin D1
TCMBANKGE007248 PGR-AS1 AT1; AT2; AT3 PGR antisense RNA 1
TCMBANKGE005805 MC1R CMM5; MSH-R; SHEP2 melanocortin 1 receptor
TCMBANKGE003940 PTN HARP; HB-GAM; HBBM; HBGF-8; HBGF8; HBNF; HBNF-1; NEGF1; OSF-1 pleiotrophin
TCMBANKGE013473 F2R CF2R; HTR; PAR-1; PAR1; TR coagulation factor II thrombin receptor
TCMBANKGE011698 ITGA5 CD49e; FNRA; VLA-5; VLA5A integrin subunit alpha 5
TCMBANKGE005627 LTBP3 DASS; GPHYSD3; LTBP-3; LTBP2; STHAG6; pp6425 latent transforming growth factor beta binding protein 3
TCMBANKGE000306 PIK3CG PI3CG; PI3K; PI3Kgamma; PIK3; p110gamma; p120-PI3K phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma
TCMBANKGE004203 TGFBR2 AAT3; FAA3; LDS1B; LDS2; LDS2B; MFS2; RIIC; TAAD2; TBR-ii; TBRII; TGFR-2; TGFbeta-RII transforming growth factor beta receptor 2
TCMBANKGE003923 NREP C5orf13; D4S114; P311; PRO1873; PTZ17; SEZ17 neuronal regeneration related protein
TCMBANKGE009774 MSH3 DUP; FAP4; MRP1 mutS homolog 3
TCMBANKGE011182 ITGB2 CD18; LAD; LCAMB; LFA-1; MAC-1; MF17; MFI7 integrin subunit beta 2
TCMBANKGE008482 HOXB9 HOX-2.5; HOX2; HOX2E homeobox B9
TCMBANKGE000722 KRT10 BCIE; BIE; CK10; EHK; K10; KPP keratin 10
TCMBANKGE003326 MARK2 EMK-1; EMK1; PAR-1; Par-1b; Par1b microtubule affinity regulating kinase 2
TCMBANKGE007151 TIMP2 CSC-21K; DDC8 TIMP metallopeptidase inhibitor 2
TCMBANKGE004410 CPOX COX; CPO; CPX; HCP coproporphyrinogen oxidase
TCMBANKGE000712 COL1A1 CAFYD; EDSARTH1; EDSC; OI1; OI2; OI3; OI4 collagen type I alpha 1 chain
TCMBANKGE000850 CYLD BRSS; CDMT; CYLD1; CYLDI; EAC; MFT; MFT1; SBS; TEM; USPL2 CYLD lysine 63 deubiquitinase
TCMBANKGE000315 IL4 BCGF-1; BCGF1; BSF-1; BSF1; IL-4 interleukin 4

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