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疾病ID:TCMBANKDI022574

疾病名:Cocaine Dependence

MeSH_Name:Chemically-Induced Disorders; Mental Disorders

HPO_Name:-

UMLS_Name:Mental or Behavioral Dysfunction

DO_Name:disease of mental health

疾病类型:disease

DisGeNET_Link:C0600427

MeSH_Link:C25; F03

HPO_Link:-

UMLS_Link:T048

DO_Link:DOID:150

HERB_ID:HBDIS010488

   疾病对应的植物
ID 拉丁名 药名 药用植物名 功能与主治 来源 药用部位 使用民族
   疾病对应的化合物
化合物ID 化合物名 别名 分子式 分子质量 Smiles
   疾病对应的靶点
靶点ID 基因名 基因别名 描述
TCMBANKGE003584 HCRTR1 OX1R hypocretin receptor 1
TCMBANKGE000259 SCARB1 CD36L1; CLA-1; CLA1; HDLQTL6; SR-BI; SRB1 scavenger receptor class B member 1
TCMBANKGE011318 NCS1 FLUP; FREQ neuronal calcium sensor 1
TCMBANKGE012410 ARC Arg3.1; hArc activity regulated cytoskeleton associated protein
TCMBANKGE001180 SMAD3 HSPC193; HsT17436; JV15-2; LDS1C; LDS3; MADH3 SMAD family member 3
TCMBANKGE000235 NTRK2 EIEE58; GP145-TrkB; OBHD; TRKB; trk-B neurotrophic receptor tyrosine kinase 2
TCMBANKGE009304 FDFT1 DGPT; ERG9; SQS; SQSD; SS farnesyl-diphosphate farnesyltransferase 1
TCMBANKGE005480 KLHL5 - kelch like family member 5
TCMBANKGE011295 MANEA ENDO; hEndo mannosidase endo-alpha
TCMBANKGE006517 SLC1A2 EAAT2; EIEE41; GLT-1; HBGT solute carrier family 1 member 2
TCMBANKGE014015 BCHE BCHED; CHE1; CHE2; E1 butyrylcholinesterase
TCMBANKGE001197 FOS AP-1; C-FOS; p55 Fos proto-oncogene, AP-1 transcription factor subunit
TCMBANKGE006911 GABRA2 EIEE78 gamma-aminobutyric acid type A receptor subunit alpha2
TCMBANKGE011654 NPS - neuropeptide S
TCMBANKGE009455 CHRM5 HM5 cholinergic receptor muscarinic 5
TCMBANKGE008011 HTR2A 5-HT2A; HTR2 5-hydroxytryptamine receptor 2A
TCMBANKGE011040 TACR3 HH11; NK-3R; NK3; NK3R; NKR; TAC3R; TAC3RL tachykinin receptor 3
TCMBANKGE000362 DNAH8 ATPase; hdhc9 dynein axonemal heavy chain 8
TCMBANKGE011659 NTNG2 LHLL9381; Lmnt2; NEDBASH; NTNG1; bA479K20.1 netrin G2
TCMBANKGE004151 PRL GHA1 prolactin
TCMBANKGE009922 GABRG2 CAE2; ECA2; EIEE74; FEB8; GEFSP3 gamma-aminobutyric acid type A receptor subunit gamma2
TCMBANKGE003242 CHRNA6 CHNRA6 cholinergic receptor nicotinic alpha 6 subunit
TCMBANKGE000311 JUND AP-1 JunD proto-oncogene, AP-1 transcription factor subunit
TCMBANKGE003079 CCKBR CCK-B; CCK2R; GASR cholecystokinin B receptor
TCMBANKGE000004 PWAR4 PAR-4; PAR4 Prader Willi/Angelman region RNA 4
TCMBANKGE004499 HOMER2 ACPD; CPD; DFNA68; HOMER-2; VESL-2 homer scaffold protein 2
TCMBANKGE001191 GRIA1 GLUH1; GLUR1; GLURA; GluA1; HBGR1 glutamate ionotropic receptor AMPA type subunit 1
TCMBANKGE005865 CAMK4 CaMK IV; CaMK-GR; CaMKIV; caMK calcium/calmodulin dependent protein kinase IV
TCMBANKGE012438 NPY2R NPY2-R neuropeptide Y receptor Y2
TCMBANKGE001136 MECP2 AUTSX3; MRX16; MRX79; MRXS13; MRXSL; PPMX; RS; RTS; RTT methyl-CpG binding protein 2
TCMBANKGE000701 ESR2 ER-BETA; ESR-BETA; ESRB; ESTRB; Erb; NR3A2; ODG8 estrogen receptor 2
TCMBANKGE013591 PNOC N/OFQ; NOP; OFQ; PPNOC; ppN/OFQ prepronociceptin
TCMBANKGE001192 HCRT NRCLP1; OX; PPOX hypocretin neuropeptide precursor
TCMBANKGE014625 OPRD1 DOP; DOR; DOR1; OPRD opioid receptor delta 1
TCMBANKGE000060 CRHR1 CRF-R; CRF-R-1; CRF-R1; CRF1; CRFR-1; CRFR1; CRH-R-1; CRH-R1; CRHR; CRHR1L corticotropin releasing hormone receptor 1
TCMBANKGE001061 CDK5 LIS7; PSSALRE cyclin dependent kinase 5
TCMBANKGE007865 LRRC7 DENSIN leucine rich repeat containing 7
TCMBANKGE013226 DRD4 D4DR dopamine receptor D4
TCMBANKGE012171 GABBR1 GABABR1; GABBR1-3; GB1; GPRC3A gamma-aminobutyric acid type B receptor subunit 1
TCMBANKGE000305 PIK3CD APDS; IMD14; P110DELTA; PI3K; p110D phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
TCMBANKGE000258 EGR1 AT225; G0S30; KROX-24; NGFI-A; TIS8; ZIF-268; ZNF225 early growth response 1
TCMBANKGE000633 ADRB2 ADRB2R; ADRBR; B2AR; BAR; BETA2AR adrenoceptor beta 2
TCMBANKGE001203 MAPK1 ERK; ERK-2; ERK2; ERT1; MAPK2; P42MAPK; PRKM1; PRKM2; p38; p40; p41; p41mapk; p42-MAPK mitogen-activated protein kinase 1
TCMBANKGE003056 GAD2 GAD65 glutamate decarboxylase 2
TCMBANKGE012155 SLC6A3 DAT; DAT1; PKDYS; PKDYS1 solute carrier family 6 member 3
TCMBANKGE000168 NR3C1 GCCR; GCR; GCRST; GR; GRL nuclear receptor subfamily 3 group C member 1
TCMBANKGE010603 FAM53B KIAA0140; bA12J10.2; smp family with sequence similarity 53 member B
TCMBANKGE005288 PDYN ADCA; PENKB; SCA23 prodynorphin
TCMBANKGE000212 GRIN1 GluN1; MRD8; NDHMSD; NDHMSR; NMD-R1; NMDA1; NMDAR1; NR1 glutamate ionotropic receptor NMDA type subunit 1
TCMBANKGE004751 GPHN GEPH; GPH; GPHRYN; HKPX1; MOCODC gephyrin
TCMBANKGE000974 SMAD5 DWFC; JV5-1; MADH5 SMAD family member 5
TCMBANKGE005747 CACNA1D CACH3; CACN4; CACNL1A2; CCHL1A2; Cav1.3; PASNA; SANDD calcium voltage-gated channel subunit alpha1 D
TCMBANKGE011923 CHRM4 HM4; M4R cholinergic receptor muscarinic 4
TCMBANKGE000078 BRD4 CAP; HUNK1; HUNKI; MCAP bromodomain containing 4
TCMBANKGE006565 NPY PYY4 neuropeptide Y
TCMBANKGE014869 HTR1B 5-HT-1B; 5-HT-1D-beta; 5-HT1B; 5-HT1DB; HTR1D2; HTR1DB; S12 5-hydroxytryptamine receptor 1B
TCMBANKGE001582 CAMK2B CAM2; CAMK2; CAMKB; CaMKIIbeta; MRD54 calcium/calmodulin dependent protein kinase II beta
TCMBANKGE000231 MAP2K1 CFC3; MAPKK1; MEK1; MKK1; PRKMK1 mitogen-activated protein kinase kinase 1
TCMBANKGE000842 SLC18A2 PKDYS2; SVAT; SVMT; VAT2; VMAT2 solute carrier family 18 member A2
TCMBANKGE010527 ARRB2 ARB2; ARR2; BARR2 arrestin beta 2
TCMBANKGE006140 PER2 FASPS; FASPS1 period circadian regulator 2
TCMBANKGE000202 RUNX2 AML3; CBF-alpha-1; CBFA1; CCD; CCD1; CLCD; OSF-2; OSF2; PEA2aA; PEBP2aA RUNX family transcription factor 2
TCMBANKGE000348 PAWR PAR4; Par-4 pro-apoptotic WT1 regulator
TCMBANKGE009420 F2RL3 PAR4 F2R like thrombin or trypsin receptor 3
TCMBANKGE000318 HMGB1 HMG-1; HMG1; HMG3; SBP-1 high mobility group box 1
TCMBANKGE001231 CRHBP CRF-BP; CRFBP corticotropin releasing hormone binding protein
TCMBANKGE013559 ANKK1 PKK2; sgK288 ankyrin repeat and kinase domain containing 1
TCMBANKGE000966 SIGMAR1 ALS16; DSMA2; OPRS1; SIG-1R; SR-BP; SR-BP1; SRBP; hSigmaR1; sigma1R sigma non-opioid intracellular receptor 1
TCMBANKGE007368 GSTP1 DFN7; FAEES3; GST3; GSTP; HEL-S-22; PI glutathione S-transferase pi 1
TCMBANKGE001154 CREB1 CREB; CREB-1 cAMP responsive element binding protein 1
TCMBANKGE003724 PRMT6 HRMT1L6 protein arginine methyltransferase 6
TCMBANKGE008743 OPRK1 K-OR-1; KOP; KOR; KOR-1; KOR1; OPRK opioid receptor kappa 1
TCMBANKGE000221 GRIA2 GLUR2; GLURB; GluA2; GluR-K2; HBGR2; gluR-2; gluR-B glutamate ionotropic receptor AMPA type subunit 2
TCMBANKGE014423 ADRA1A ADRA1C; ADRA1L1; ALPHA1AAR adrenoceptor alpha 1A
TCMBANKGE001230 HOMER1 HOMER; HOMER1A; HOMER1B; HOMER1C; SYN47; Ves-1 homer scaffold protein 1
TCMBANKGE009974 CLOCK KAT13D; bHLHe8 clock circadian regulator
TCMBANKGE000307 PIK3CB P110BETA; PI3K; PI3KBETA; PIK3C1 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
TCMBANKGE012889 OPRL1 KOR-3; KOR3; NOCIR; NOP; NOPr; OOR; OPRL; ORL1 opioid related nociceptin receptor 1
TCMBANKGE001158 LEP LEPD; OB; OBS leptin
TCMBANKGE008172 MAOA BRNRS; MAO-A monoamine oxidase A
TCMBANKGE004376 TAAR1 TA1; TAR1; TRAR1 trace amine associated receptor 1
TCMBANKGE007113 HDAC4 AHO3; BDMR; HA6116; HD4; HDAC-4; HDAC-A; HDACA histone deacetylase 4
TCMBANKGE002445 GHRL MTLRP ghrelin and obestatin prepropeptide
TCMBANKGE008702 OPRM1 LMOR; M-OR-1; MOP; MOR; MOR1; OPRM opioid receptor mu 1
TCMBANKGE005340 BAZ1A ACF1; WALp1; WCRF180; hACF1 bromodomain adjacent to zinc finger domain 1A
TCMBANKGE000158 RHOA ARH12; ARHA; EDFAOB; RHO12; RHOH12 ras homolog family member A
TCMBANKGE012345 DRD3 D3DR; ETM1; FET1 dopamine receptor D3
TCMBANKGE009105 CHRNB3 - cholinergic receptor nicotinic beta 3 subunit
TCMBANKGE000471 POMC ACTH; CLIP; LPH; MSH; NPP; OBAIRH; POC proopiomelanocortin
TCMBANKGE003418 GRM5 GPRC1E; MGLUR5; PPP1R86; mGlu5 glutamate metabotropic receptor 5
TCMBANKGE011882 EHMT2 BAT8; C6orf30; G9A; GAT8; KMT1C; NG36 euchromatic histone lysine methyltransferase 2
TCMBANKGE000310 FOSB AP-1; G0S3; GOS3; GOSB FosB proto-oncogene, AP-1 transcription factor subunit
TCMBANKGE005062 CHRNB4 - cholinergic receptor nicotinic beta 4 subunit
TCMBANKGE000410 NTNG1 Lmnt1 netrin G1
TCMBANKGE003046 AVP ADH; ARVP; AVP-NPII; AVRP; VP arginine vasopressin
TCMBANKGE012945 RPS6KA5 MSK1; MSPK1; RLPK ribosomal protein S6 kinase A5
TCMBANKGE001455 CARTPT CART CART prepropeptide
TCMBANKGE000022 CAMK2A CAMKA; CaMKIINalpha; CaMKIIalpha; MRD53; MRT63 calcium/calmodulin dependent protein kinase II alpha
TCMBANKGE011342 NGF Beta-NGF; HSAN5; NGFB nerve growth factor
TCMBANKGE007459 DBH DBM; ORTHYP1 dopamine beta-hydroxylase
TCMBANKGE001978 GRM2 GLUR2; GPRC1B; MGLUR2; mGlu2 glutamate metabotropic receptor 2
TCMBANKGE000659 TLR3 CD283; IIAE2 toll like receptor 3
TCMBANKGE000590 ILK HEL-S-28; ILK-1; ILK-2; P59; p59ILK integrin linked kinase
TCMBANKGE003127 WDHD1 AND-1; AND1; CHTF4; CTF4 WD repeat and HMG-box DNA binding protein 1
TCMBANKGE008845 GALR1 GALNR; GALNR1 galanin receptor 1
TCMBANKGE000530 SPINT2 DIAR3; HAI-2; HAI2; Kop; PB serine peptidase inhibitor, Kunitz type 2
TCMBANKGE014670 NCOR2 CTG26; N-CoR2; SMAP270; SMRT; SMRTE; SMRTE-tau; TNRC14; TRAC; TRAC-1; TRAC1 nuclear receptor corepressor 2
TCMBANKGE006220 ATP2C2 SPCA2 ATPase secretory pathway Ca2+ transporting 2
TCMBANKGE003602 CES2 CE-2; CES2A1; PCE-2; iCE carboxylesterase 2
TCMBANKGE003656 NFAT5 NF-AT5; NFATL1; NFATZ; OREBP; TONEBP nuclear factor of activated T cells 5
TCMBANKGE008417 GPSM1 AGS3 G protein signaling modulator 1
TCMBANKGE000251 FGF2 BFGF; FGF-2; FGFB; HBGF-2 fibroblast growth factor 2
TCMBANKGE009155 CHRNA5 LNCR2 cholinergic receptor nicotinic alpha 5 subunit
TCMBANKGE000398 MIR137 MIRN137; miR-137 microRNA 137
TCMBANKGE001004 MIR301B MIRN301B; mir-301b microRNA 301b
TCMBANKGE000264 ABCB1 ABC20; CD243; CLCS; GP170; MDR1; P-GP; PGY1 ATP binding cassette subfamily B member 1
TCMBANKGE000219 CCR5 CC-CKR-5; CCCKR5; CCR-5; CD195; CKR-5; CKR5; CMKBR5; IDDM22 C-C motif chemokine receptor 5
TCMBANKGE000977 SMAD1 BSP-1; BSP1; JV4-1; JV41; MADH1; MADR1 SMAD family member 1
TCMBANKGE001193 GDNF ATF; ATF1; ATF2; HFB1-GDNF; HSCR3 glial cell derived neurotrophic factor
TCMBANKGE001096 TLR4 ARMD10; CD284; TLR-4; TOLL toll like receptor 4
TCMBANKGE000899 GLI2 CJS; HPE9; PHS2; THP1; THP2 GLI family zinc finger 2
TCMBANKGE001201 MAPK3 ERK-1; ERK1; ERT2; HS44KDAP; HUMKER1A; P44ERK1; P44MAPK; PRKM3; p44-ERK1; p44-MAPK mitogen-activated protein kinase 3
TCMBANKGE014932 COMT HEL-S-98n catechol-O-methyltransferase
TCMBANKGE005923 TPH2 ADHD7; NTPH tryptophan hydroxylase 2
TCMBANKGE000801 HTR1A 5-HT-1A; 5-HT1A; 5HT1a; ADRB2RL1; ADRBRL1; G-21; PFMCD 5-hydroxytryptamine receptor 1A
TCMBANKGE014473 CRH CRF; CRH1 corticotropin releasing hormone
TCMBANKGE012835 STK38 NDR; NDR1 serine/threonine kinase 38
TCMBANKGE000551 NOL3 ARC; FCM; MYOCL1; MYP; NOP; NOP30 nucleolar protein 3
TCMBANKGE009407 TYK2 IMD35; JTK1 tyrosine kinase 2
TCMBANKGE001313 SMURF1 - SMAD specific E3 ubiquitin protein ligase 1
TCMBANKGE000555 SST SMST somatostatin
TCMBANKGE000869 DRD2 D2DR; D2R dopamine receptor D2
TCMBANKGE010467 MC4R BMIQ20 melanocortin 4 receptor
TCMBANKGE001001 SNCA NACP; PARK1; PARK4; PD1 synuclein alpha
TCMBANKGE009997 PER1 PER; RIGUI; hPER period circadian regulator 1
TCMBANKGE003625 SLC6A4 5-HTT; 5-HTTLPR; 5HTT; HTT; OCD1; SERT; SERT1; hSERT solute carrier family 6 member 4
TCMBANKGE012559 CRHR2 CRF-RB; CRF2; CRFR2; HM-CRF corticotropin releasing hormone receptor 2
TCMBANKGE000425 DRD1 DADR; DRD1A dopamine receptor D1
TCMBANKGE000306 PIK3CG PI3CG; PI3K; PI3Kgamma; PIK3; p110gamma; p120-PI3K phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma
TCMBANKGE000236 BDNF ANON2; BULN2 brain derived neurotrophic factor
TCMBANKGE000514 CNR1 CANN6; CB-R; CB1; CB1A; CB1K5; CB1R; CNR cannabinoid receptor 1
TCMBANKGE002612 HDAC5 HD5; NY-CO-9 histone deacetylase 5
TCMBANKGE005717 COL21A1 COLA1L; FP633 collagen type XXI alpha 1 chain
TCMBANKGE014746 CES1 ACAT; CE-1; CEH; CES2; HMSE; HMSE1; PCE-1; REH; SES1; TGH; hCE-1 carboxylesterase 1
TCMBANKGE008870 NLN AGTBP; EP24.16; MEP; MOP neurolysin
TCMBANKGE003934 HTR2C 5-HT1C; 5-HT2C; 5-HTR2C; 5HTR2C; HTR1C 5-hydroxytryptamine receptor 2C
TCMBANKGE014749 KCTD20 C6orf69; dJ108K11.3 potassium channel tetramerization domain containing 20
TCMBANKGE000557 ATP9B ATPASEP; ATPIIB; HUSSY-20; NEO1L; hMMR1 ATPase phospholipid transporting 9B (putative)
TCMBANKGE003672 CALM1 CALML2; CAM2; CAM3; CAMB; CAMC; CAMI; CAMIII; CPVT4; DD132; LQT14; PHKD; caM calmodulin 1
TCMBANKGE011775 OPN4 MOP opsin 4
TCMBANKGE000054 GAD1 CPSQ1; GAD; SCP glutamate decarboxylase 1
TCMBANKGE003271 RGS4 RGP4; SCZD9 regulator of G protein signaling 4
TCMBANKGE011186 CHRNA3 BAIPRCK; LNCR2; NACHRA3; PAOD2 cholinergic receptor nicotinic alpha 3 subunit

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