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SIGMAR1

靶点ID:TCMBANKGE000966

靶点别名:ALS16; DSMA2; OPRS1; SIG-1R; SR-BP; SR-BP1; SRBP; hSigmaR1; sigma1R

靶点描述:sigma non-opioid intracellular receptor 1

染色体:9

染色体位置:9p13.3

靶点类型:protein-coding

HERB_ID:-

HGNC_Link:8157

OMIM_Link:601978

Ensembl_Link:ENSG00000147955

靶点对应的植物

ID	拉丁名	药名	药用植物名	功能与主治	来源	药用部位	使用民族

靶点对应的化合物

化合物ID	化合物名	别名	分子式	分子质量	Smiles

TCMBANKIN000075	picrotoxin		C30H34O13	602.6 g/mol	CC(=C)C1C2C3C4(C(C1C(=O)O2)(CC5C4(O5)C(=O)O3)O)C.CC12C3C4C(C(C1(CC5C2(O5)C(=O)O3)O)C(=O)O4)C(C)(C)O
TCMBANKIN003665	evoden				C1CCN(CC1)CCOC2=CC=C(C=C2)C(=O)C3=C(SC4=C3C=CC(=C4)O)C5=CC=C(C=C5)O
TCMBANKIN016901	N-methyl-2-β-Hydroxypropyl piperidine		C21H27NO2		CC(C(C1=CC=C(C=C1)O)O)N2CCC(CC2)CC3=CC=CC=C3
TCMBANKIN022547	n,n-dimethyltryptamine	EINECS 200-508-4; ZINC897457; MB00483; 2-(1H-Indol-3-yl)-N,N-dimethylethanamine #; AN-41827; Indolalkylamine der; GTPL141; FT-0667348; BRN 0138259; WUB601BHAA; DB01488; 61-50-7; WLN: T56 BMJ D2N1&1; FCH838678; AKOS005446117; STK370594; Dimethyltryptamine(DMT); DTXSID60110053; N,N-Dimethyltryptamine, >=97% (HPLC); 2-(1H-indol-3-yl)-N,N-dimethylethylamine; 3-[2- (dimethylamino)ethyl]-Indole; N,N-dimethyl-1H-Indole-3-ethanamine (9CI); AC1L1LS3; KB-296215; 2-(1H-Indol-3-yl)-N,N-dimethylethanamine; SCHEMBL335710; NSC63795; 061D507; N,N-Dimethyltryptamine, free base; N,N-DIMETHYLTRYPTAMINE; DIMETHYLTRYPTAMINE; 1H-Indole-3-ethanamine, N,N-dimethyl-; N,N-dimethyl-1H-Indole-3-ethanamine; 1H-INDOLE-3-ETHANAMINE,N,N-DIMETHYL; InChI=1/C12H16N2/c1-14(2)8-7-10-9-13-12-6-4-3-5-11(10)12/h3-6,9,13H,7-8H2,1-2H; 3-(2-(dimethylamino)ethyl)-Indole; Indole, 3-[2-(dimethylamino)ethyl]-; D-5500; (2-Indol-3-ylethyl)dimethylamine; LS-82930; 2-(1H-indol-3-yl)-N,N-dimethylethanamine (ACD/Name 4.0); [2-(1H-indol-3-yl)ethyl]dimethylamine; 2-(3-Indolyl)ethyldimethylamine; 2-(1H-INDOL-3-YL)-N,N-DIMETHYL-ETHANAMINE; NSC-63795; CHEMBL12420; DMT (psychogenic); UNII-WUB601BHAA; MFCD00055989; Indole, 3-(2-(dimethylamino)ethyl)-; N,N-Dimethyltryptamine (DMT) solution, 1.0 mg/mL in methanol, certified reference material; D0K1QS; DEA No. 7435; N-(2-(1H-indol-3-yl)ethyl)-N,N-dimethylamine (ACD/Name 4.0); [2-(1H-INDOL-3-YL)-ETHYL]-DIMETHYL-AMINE; CHEBI:28969; BDBM50026868; 2-(1H-indol-3-yl)-ethyl-dimethyl-amine; 1H-Indole-3-ethanamine, N,N-dimethyl- (9CI); 3-[2-(dimethylamino)ethyl]indole; 3-(2-Dimethylaminoethyl)indole; NSC 63795; 3-(2-DIMETHYLAMINOETHYL) INDOLE; L001288; CTK5B3344; DMULVCHRPCFFGV-UHFFFAOYSA-N; 1H-Indole-3-ethanamine,N,N-dimethyl-; C08302; HSDB 8017; 3-(dimethylaminoethyl)-indole; N,N-Dimethyl-1H-indole-3-ethylamine; (psychogenic); 68677-25-8	C12H16N2	188.27 g/mol	CN(C)CCC1=CNC2=CC=CC=C21
TCMBANKIN061675	berberime	berberine ; isoquinoline alkaloid; berberine	C20H18NO4+	336.4 g/mol	COC1=C(C2=C[N+]3=C(C=C2C=C1)C4=CC5=C(C=C4CC3)OCO5)OC

靶点对应的疾病

疾病ID	疾病名	MeSH名	HPO名	UMLS名	疾病类型

TCMBANKDI000004	Pathological Conditions, Signs and Symptoms	Constitutional symptom	Sign or Symptom	phenotype
TCMBANKDI000054	Nervous System Diseases; Mental Disorders	Abnormality of the nervous system	Disease or Syndrome	disease
TCMBANKDI000166	-	-	Neoplastic Process	disease
TCMBANKDI001054	Nervous System Diseases	-	Disease or Syndrome	disease
TCMBANKDI002065	Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders	-	Mental or Behavioral Dysfunction	group
TCMBANKDI002779	-	Abnormality of the nervous system	Finding	phenotype
TCMBANKDI003248	Nutritional and Metabolic Diseases; Endocrine System Diseases	Abnormality of metabolism/homeostasis; Abnormality of the endocrine system	Disease or Syndrome	disease
TCMBANKDI003353	Pathological Conditions, Signs and Symptoms; Neoplasms	-	Neoplastic Process	phenotype
TCMBANKDI003411	-	-	Disease or Syndrome	disease
TCMBANKDI004331	Pathological Conditions, Signs and Symptoms; Nervous System Diseases	-	Disease or Syndrome	phenotype
TCMBANKDI004509	-	-	Disease or Syndrome	disease
TCMBANKDI004922	Nutritional and Metabolic Diseases; Nervous System Diseases; Mental Disorders	-	Mental or Behavioral Dysfunction	disease
TCMBANKDI005272	Pathological Conditions, Signs and Symptoms; Nervous System Diseases	-	Sign or Symptom	phenotype
TCMBANKDI006652	Nutritional and Metabolic Diseases; Nervous System Diseases; Mental Disorders	Abnormality of the nervous system	Disease or Syndrome	disease
TCMBANKDI007012	Pathological Conditions, Signs and Symptoms; Nervous System Diseases	-	Pathologic Function	phenotype
TCMBANKDI007343	Pathological Conditions, Signs and Symptoms; Nervous System Diseases	-	Finding	phenotype
TCMBANKDI009231	Pathological Conditions, Signs and Symptoms; Infections	Abnormality of the immune system	Disease or Syndrome	disease
TCMBANKDI009278	Mental Disorders	-	Mental or Behavioral Dysfunction	group
TCMBANKDI009702	Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases	Abnormality of the cardiovascular system	Disease or Syndrome	phenotype
TCMBANKDI010239	Chemically-Induced Disorders; Mental Disorders	-	Mental or Behavioral Dysfunction	group
TCMBANKDI011743	Neoplasms; Skin and Connective Tissue Diseases	Neoplasm; Abnormality of the breast	Neoplastic Process	group
TCMBANKDI012157	Nervous System Diseases	Abnormality of the nervous system	Disease or Syndrome	group
TCMBANKDI012932	Infections; Immune System Diseases	-	Disease or Syndrome	group
TCMBANKDI014132	Pathological Conditions, Signs and Symptoms; Nervous System Diseases	Abnormality of the nervous system	Disease or Syndrome	disease
TCMBANKDI014531	Pathological Conditions, Signs and Symptoms; Neoplasms; Musculoskeletal Diseases	-	Neoplastic Process	disease
TCMBANKDI015485	Mental Disorders	Abnormality of the nervous system	Mental or Behavioral Dysfunction	disease
TCMBANKDI016439	Nervous System Diseases	-	Disease or Syndrome	disease
TCMBANKDI017837	Pathological Conditions, Signs and Symptoms; Nervous System Diseases	Abnormality of the nervous system	Disease or Syndrome	disease
TCMBANKDI017965	Pathological Conditions, Signs and Symptoms; Nervous System Diseases	Abnormality of the nervous system	Finding	phenotype
TCMBANKDI018017	Pathological Conditions, Signs and Symptoms; Nervous System Diseases	-	Sign or Symptom	phenotype
TCMBANKDI018958	Nutritional and Metabolic Diseases; Nervous System Diseases	-	Disease or Syndrome	disease
TCMBANKDI019398	Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases	Abnormality of the genitourinary system	Finding	phenotype
TCMBANKDI020808	Nervous System Diseases	-	Disease or Syndrome	disease
TCMBANKDI022574	Chemically-Induced Disorders; Mental Disorders	-	Mental or Behavioral Dysfunction	disease
TCMBANKDI024057	Pathological Conditions, Signs and Symptoms; Nervous System Diseases	-	Disease or Syndrome	phenotype
TCMBANKDI024134	Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Behavior and Behavior Mechanisms	-	Mental or Behavioral Dysfunction	phenotype
TCMBANKDI025535	-	-	Sign or Symptom	phenotype
TCMBANKDI027289	Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Behavior and Behavior Mechanisms	-	Mental or Behavioral Dysfunction	disease
TCMBANKDI028170	Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders	-	Finding	phenotype
TCMBANKDI029084	Pathological Conditions, Signs and Symptoms	-	Sign or Symptom	phenotype
TCMBANKDI030081	Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms	-	Mental or Behavioral Dysfunction	phenotype
TCMBANKDI031754	Pathological Conditions, Signs and Symptoms; Nervous System Diseases	-	Pathologic Function	phenotype
TCMBANKDI032193	Behavior and Behavior Mechanisms	Abnormality of the nervous system	Mental or Behavioral Dysfunction	phenotype
TCMBANKDI032222	Nervous System Diseases; Mental Disorders	-	Mental or Behavioral Dysfunction	disease