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疾病ID:TCMBANKDI023336
疾病名:Paraganglioma
MeSH_Name:Neoplasms
HPO_Name:Abnormality of the endocrine system; Abnormality of the nervous system; Neoplasm
UMLS_Name:Neoplastic Process
DO_Name:genetic disease; disease of anatomical entity; disease of cellular proliferation
疾病类型:disease
DisGeNET_Link:C0030421
MeSH_Link:C04
HPO_Link:HP:0000818; HP:0000707; HP:0002664
UMLS_Link:T191
DO_Link:DOID:630; DOID:7; DOID:14566
HERB_ID:-
疾病对应的植物
| ID | 拉丁名 | 药名 | 药用植物名 | 功能与主治 | 来源 | 药用部位 | 使用民族 |
|---|
疾病对应的化合物
| 化合物ID | 化合物名 | 别名 | 分子式 | 分子质量 | Smiles |
|---|
疾病对应的靶点
| 靶点ID | 基因名 | 基因别名 | 描述 |
|---|
| TCMBANKGE000737 | PGR | NR3C3; PR | progesterone receptor |
| TCMBANKGE012979 | CDC73 | C1orf28; FIHP; HPTJT; HRPT1; HRPT2; HYX | cell division cycle 73 |
| TCMBANKGE015137 | ARTN | ART; ENOVIN; EVN; NBN | artemin |
| TCMBANKGE001111 | KIT | C-Kit; CD117; MASTC; PBT; SCFR | KIT proto-oncogene, receptor tyrosine kinase |
| TCMBANKGE001033 | FGFR1 | BFGFR; CD331; CEK; ECCL; FGFBR; FGFR-1; FLG; FLT-2; FLT2; HBGFR; HH2; HRTFDS; KAL2; N-SAM; OGD; bFGF-R-1 | fibroblast growth factor receptor 1 |
| TCMBANKGE009616 | SLC22A18 | BWR1A; BWSCR1A; HET; IMPT1; ITM; ORCTL2; SLC22A1L; TSSC5; p45-BWR1A | solute carrier family 22 member 18 |
| TCMBANKGE012744 | NRTN | NTN | neurturin |
| TCMBANKGE004479 | PPP2R1B | PP2A-Abeta; PR65B | protein phosphatase 2 scaffold subunit Abeta |
| TCMBANKGE004939 | INSM1 | IA-1; IA1 | INSM transcriptional repressor 1 |
| TCMBANKGE000567 | CDKN2A | ARF; CDK4I; CDKN2; CMM2; INK4; INK4A; MLM; MTS-1; MTS1; P14; P14ARF; P16; P16-INK4A; P16INK4; P16INK4A; P19; P19ARF; TP16 | cyclin dependent kinase inhibitor 2A |
| TCMBANKGE000173 | BRAF | B-RAF1; B-raf; BRAF1; NS7; RAFB1 | B-Raf proto-oncogene, serine/threonine kinase |
| TCMBANKGE010385 | CNTN4 | AXCAM; BIG-2 | contactin 4 |
| TCMBANKGE007681 | ENPEP | APA; CD249; gp160 | glutamyl aminopeptidase |
| TCMBANKGE001089 | PARP1 | ADPRT; ADPRT 1; ADPRT1; ARTD1; PARP; PARP-1; PPOL; pADPRT-1 | poly(ADP-ribose) polymerase 1 |
| TCMBANKGE000596 | PSMD9 | Rpn4; p27 | proteasome 26S subunit, non-ATPase 9 |
| TCMBANKGE008865 | FOLH1 | FGCP; FOLH; GCP2; GCPII; NAALAD1; NAALAdase; PSM; PSMA; mGCP | folate hydrolase 1 |
| TCMBANKGE000359 | MDH2 | EIEE51; M-MDH; MDH; MGC:3559; MOR1 | malate dehydrogenase 2 |
| TCMBANKGE002065 | PRDM2 | HUMHOXY1; KMT8; KMT8A; MTB-ZF; RIZ; RIZ1; RIZ2 | PR/SET domain 2 |
| TCMBANKGE008464 | RBP1 | CRABP-I; CRBP; CRBP1; CRBPI; RBPC | retinol binding protein 1 |
| TCMBANKGE014812 | SSTR2 | - | somatostatin receptor 2 |
| TCMBANKGE000135 | CXCR4 | CD184; D2S201E; FB22; HM89; HSY3RR; LAP-3; LAP3; LCR1; LESTR; NPY3R; NPYR; NPYRL; NPYY3R; WHIM; WHIMS | C-X-C motif chemokine receptor 4 |
| TCMBANKGE000435 | PROM1 | AC133; CD133; CORD12; MCDR2; MSTP061; PROML1; RP41; STGD4 | prominin 1 |
| TCMBANKGE001146 | SNAI1 | SLUGH2; SNA; SNAH; SNAIL; SNAIL1; dJ710H13.1 | snail family transcriptional repressor 1 |
| TCMBANKGE007180 | EGLN2 | EIT-6; EIT6; HIF-PH1; HIFPH1; HPH-1; HPH-3; PHD1 | egl-9 family hypoxia inducible factor 2 |
| TCMBANKGE001074 | ATM | AT1; ATA; ATC; ATD; ATDC; ATE; TEL1; TELO1 | ATM serine/threonine kinase |
| TCMBANKGE000925 | PCNA | ATLD2 | proliferating cell nuclear antigen |
| TCMBANKGE003113 | CX3CL1 | ABCD-3; C3Xkine; CXC3; CXC3C; NTN; NTT; SCYD1; fractalkine; neurotactin | C-X3-C motif chemokine ligand 1 |
| TCMBANKGE000031 | DNMT3A | DNMT3A2; HESJAS; M.HsaIIIA; TBRS | DNA methyltransferase 3 alpha |
| TCMBANKGE000448 | MTA1 | - | metastasis associated 1 |
| TCMBANKGE000987 | COL11A2 | DFNA13; DFNB53; FBCG2; HKE5; OSMEDA; OSMEDB; PARP; STL3 | collagen type XI alpha 2 chain |
| TCMBANKGE012153 | BMS1 | ACC; BMS1L | BMS1 ribosome biogenesis factor |
| TCMBANKGE000989 | ACACA | ACAC; ACACAD; ACC; ACC1; ACCA | acetyl-CoA carboxylase alpha |
| TCMBANKGE004375 | CDKN1C | BWCR; BWS; KIP2; WBS; p57; p57Kip2 | cyclin dependent kinase inhibitor 1C |
| TCMBANKGE000594 | ZNRD2 | SSSCA1; p27 | zinc ribbon domain containing 2 |
| TCMBANKGE010703 | DAXX | BING2; DAP6; EAP1; SMIM40 | death domain associated protein |
| TCMBANKGE013860 | EDNRA | ET-A; ETA; ETA-R; ETAR; ETRA; MFDA; hET-AR | endothelin receptor type A |
| TCMBANKGE014297 | KRIT1 | CAM; CCM1 | KRIT1 ankyrin repeat containing |
| TCMBANKGE000986 | ERBB2 | CD340; HER-2; HER-2/neu; HER2; MLN 19; NEU; NGL; TKR1 | erb-b2 receptor tyrosine kinase 2 |
| TCMBANKGE005000 | PDE11A | PPNAD2 | phosphodiesterase 11A |
| TCMBANKGE001437 | NME1 | AWD; GAAD; NB; NBS; NDKA; NDPK-A; NDPKA; NM23; NM23-H1 | NME/NM23 nucleoside diphosphate kinase 1 |
| TCMBANKGE001257 | RET | CDHF12; CDHR16; HSCR1; MEN2A; MEN2B; MTC1; PTC; RET-ELE1 | ret proto-oncogene |
| TCMBANKGE005145 | SDHC | CYB560; CYBL; PGL3; QPS1; SDH3 | succinate dehydrogenase complex subunit C |
| TCMBANKGE013523 | ENG | END; HHT1; ORW1 | endoglin |
| TCMBANKGE011733 | JAG2 | HJ2; SER2 | jagged canonical Notch ligand 2 |
| TCMBANKGE009256 | SLC6A2 | NAT1; NET; NET1; SLC6A5 | solute carrier family 6 member 2 |
| TCMBANKGE000331 | CALCA | CALC1; CGRP; CGRP-I; CGRP-alpha; CGRP1; CT; KC; PCT | calcitonin related polypeptide alpha |
| TCMBANKGE012082 | SDHAF2 | C11orf79; PGL2; SDH5 | succinate dehydrogenase complex assembly factor 2 |
| TCMBANKGE000825 | CDKN1B | CDKN4; KIP1; MEN1B; MEN4; P27KIP1 | cyclin dependent kinase inhibitor 1B |
| TCMBANKGE012249 | DLST | DLTS; KGD2; PGL7 | dihydrolipoamide S-succinyltransferase |
| TCMBANKGE000842 | SLC18A2 | PKDYS2; SVAT; SVMT; VAT2; VMAT2 | solute carrier family 18 member A2 |
| TCMBANKGE000600 | IFI27 | FAM14D; ISG12; ISG12A; P27 | interferon alpha inducible protein 27 |
| TCMBANKGE007884 | GPR68 | AI2A6; GPR12A; OGR1 | G protein-coupled receptor 68 |
| TCMBANKGE000898 | MYC | MRTL; MYCC; bHLHe39; c-Myc | MYC proto-oncogene, bHLH transcription factor |
| TCMBANKGE002699 | TH | DYT14; DYT5b; TYH | tyrosine hydroxylase |
| TCMBANKGE013396 | CHGA | CGA | chromogranin A |
| TCMBANKGE001097 | HIF1A | HIF-1-alpha; HIF-1A; HIF-1alpha; HIF1; HIF1-ALPHA; MOP1; PASD8; bHLHe78 | hypoxia inducible factor 1 subunit alpha |
| TCMBANKGE003499 | RASSF1 | 123F2; NORE2A; RASSF1A; RDA32; REH3P21 | Ras association domain family member 1 |
| TCMBANKGE003415 | GATA3 | HDR; HDRS | GATA binding protein 3 |
| TCMBANKGE008107 | S100A1 | S100; S100-alpha; S100A | S100 calcium binding protein A1 |
| TCMBANKGE000597 | TMED7 | CGI-109; p24g3; p24gamma3; p27 | transmembrane p24 trafficking protein 7 |
| TCMBANKGE007038 | SDS | SDH | serine dehydratase |
| TCMBANKGE010551 | NES | Nbla00170 | nestin |
| TCMBANKGE001073 | PTGS2 | COX-2; COX2; GRIPGHS; PGG/HS; PGHS-2; PHS-2; hCox-2 | prostaglandin-endoperoxide synthase 2 |
| TCMBANKGE005120 | TRAP1 | HSP 75; HSP75; HSP90L; TRAP-1 | TNF receptor associated protein 1 |
| TCMBANKGE000728 | MGMT | - | O-6-methylguanine-DNA methyltransferase |
| TCMBANKGE009478 | MYO5B | - | myosin VB |
| TCMBANKGE008001 | MIB1 | DIP-1; DIP1; LVNC7; MIB; ZZANK2; ZZZ6 | mindbomb E3 ubiquitin protein ligase 1 |
| TCMBANKGE010402 | NF1 | NFNS; VRNF; WSS | neurofibromin 1 |
| TCMBANKGE001141 | PPARA | NR1C1; PPAR; PPARalpha; hPPAR | peroxisome proliferator activated receptor alpha |
| TCMBANKGE001088 | SMAD4 | DPC4; JIP; MADH4; MYHRS | SMAD family member 4 |
| TCMBANKGE000482 | IDH1 | HEL-216; HEL-S-26; IDCD; IDH; IDP; IDPC; PICD | isocitrate dehydrogenase (NADP(+)) 1 |
| TCMBANKGE008328 | PDP1 | PDH; PDP; PDPC; PPM2A; PPM2C | pyruvate dehyrogenase phosphatase catalytic subunit 1 |
| TCMBANKGE000784 | CALM3 | CALM; CAM1; CAM2; CAMB; CPVT6; CaM; CaMIII; HEL-S-72; LQT16; PHKD; PHKD3 | calmodulin 3 |
| TCMBANKGE000257 | FLT1 | FLT; FLT-1; VEGFR-1; VEGFR1 | fms related receptor tyrosine kinase 1 |
| TCMBANKGE003195 | PDGFRB | CD140B; IBGC4; IMF1; JTK12; KOGS; PDGFR; PDGFR-1; PDGFR1; PENTT | platelet derived growth factor receptor beta |
| TCMBANKGE007487 | VHL | HRCA1; RCA1; VHL1; pVHL | von Hippel-Lindau tumor suppressor |
| TCMBANKGE010021 | CHGB | SCG1 | chromogranin B |
| TCMBANKGE000787 | VCAM1 | CD106; INCAM-100 | vascular cell adhesion molecule 1 |
| TCMBANKGE013794 | CMAS | CSS | cytidine monophosphate N-acetylneuraminic acid synthetase |
| TCMBANKGE006691 | FGFR3 | ACH; CD333; CEK2; HSFGFR3EX; JTK4 | fibroblast growth factor receptor 3 |
| TCMBANKGE000935 | S100B | NEF; S100; S100-B; S100beta | S100 calcium binding protein B |
| TCMBANKGE001199 | PDGFRA | CD140A; PDGFR-2; PDGFR2 | platelet derived growth factor receptor alpha |
| TCMBANKGE000471 | POMC | ACTH; CLIP; LPH; MSH; NPP; OBAIRH; POC | proopiomelanocortin |
| TCMBANKGE012203 | FH | FMRD; HLRCC; HsFH; LRCC; MCL; MCUL1 | fumarate hydratase |
| TCMBANKGE005556 | CAMKMT | C2orf34; CLNMT; CaM KMT; Cam; KMT | calmodulin-lysine N-methyltransferase |
| TCMBANKGE002693 | SDHA | CMD1GG; FP; PGL5; SDH1; SDH2; SDHF | succinate dehydrogenase complex flavoprotein subunit A |
| TCMBANKGE001160 | CD274 | B7-H; B7H1; PD-L1; PDCD1L1; PDCD1LG1; PDL1; hPD-L1 | CD274 molecule |
| TCMBANKGE013002 | NNMT | - | nicotinamide N-methyltransferase |
| TCMBANKGE000445 | CD44 | CDW44; CSPG8; ECMR-III; HCELL; HUTCH-I; IN; LHR; MC56; MDU2; MDU3; MIC4; Pgp1 | CD44 molecule (Indian blood group) |
| TCMBANKGE013929 | GNA12 | NNX3; RMP; gep | G protein subunit alpha 12 |
| TCMBANKGE002680 | SCO2 | CEMCOX1; ECGF1; Gliostatin; MYP6; PD-ECGF; SCO1L; TP; TYMP; TdRPase | synthesis of cytochrome C oxidase 2 |
| TCMBANKGE002949 | ENO2 | HEL-S-279; NSE | enolase 2 |
| TCMBANKGE007459 | DBH | DBM; ORTHYP1 | dopamine beta-hydroxylase |
| TCMBANKGE000643 | TTR | ATTR; CTS; CTS1; HEL111; HsT2651; PALB; TBPA | transthyretin |
| TCMBANKGE000690 | SYP | MRX96; MRXSYP | synaptophysin |
| TCMBANKGE013113 | NLGN4X | ASPGX2; AUTSX2; HLNX; HNL4X; NLGN4 | neuroligin 4 X-linked |
| TCMBANKGE006217 | TET1 | CXXC6; LCX; bA119F7.1 | tet methylcytosine dioxygenase 1 |
| TCMBANKGE001021 | MUC1 | ADMCKD; ADMCKD1; CA 15-3; CD227; EMA; H23AG; KL-6; MAM6; MCD; MCKD; MCKD1; MUC-1; MUC-1/SEC; MUC-1/X; MUC1/ZD; PEM; PEMT; PUM | mucin 1, cell surface associated |
| TCMBANKGE006100 | CSF2RA | CD116; CDw116; CSF2R; CSF2RAX; CSF2RAY; CSF2RX; CSF2RY; GM-CSF-R-alpha; GMCSFR; GMCSFR-alpha; GMR; GMR-alpha; SMDP4; alphaGMR | colony stimulating factor 2 receptor subunit alpha |
| TCMBANKGE000136 | MKI67 | KIA; MIB-; MIB-1; PPP1R105 | marker of proliferation Ki-67 |
| TCMBANKGE010166 | TYMP | ECGF; ECGF1; MEDPS1; MNGIE; MTDPS1; PDECGF; TP; hPD-ECGF | thymidine phosphorylase |
| TCMBANKGE007610 | PDE8B | ADSD; PPNAD3 | phosphodiesterase 8B |
| TCMBANKGE001044 | RPS6KB1 | PS6K; S6K; S6K-beta-1; S6K1; STK14A; p70 S6KA; p70(S6K)-alpha; p70-S6K; p70-alpha | ribosomal protein S6 kinase B1 |
| TCMBANKGE001056 | KRAS | C-K-RAS; C-K-RAS; CFC2; K-RAS2A; K-RAS2B; K-RAS4A; K-RAS4B; K-Ras; K-Ras 2; KI-RAS; KRAS1; KRAS2; NS; NS3; OES; RALD; RASK2; c-Ki-ras; c-Ki-ras2 | KRAS proto-oncogene, GTPase |
| TCMBANKGE000286 | GSK3B | - | glycogen synthase kinase 3 beta |
| TCMBANKGE010995 | GUSB | BG; MPS7 | glucuronidase beta |
| TCMBANKGE001200 | STMN1 | C1orf215; LAP18; Lag; OP18; PP17; PP19; PR22; SMN | stathmin 1 |
| TCMBANKGE001140 | FGF21 | - | fibroblast growth factor 21 |
| TCMBANKGE010948 | SARDH | BPR-2; DMGDHL1; SAR; SARD; SDH | sarcosine dehydrogenase |
| TCMBANKGE000377 | MITF | CMM8; COMMAD; MI; WS2; WS2A; bHLHe32 | melanocyte inducing transcription factor |
| TCMBANKGE011953 | MEN1 | MEAI; SCG2 | menin 1 |
| TCMBANKGE008754 | H3P10 | p16 | H3 histone pseudogene 10 |
| TCMBANKGE001193 | GDNF | ATF; ATF1; ATF2; HFB1-GDNF; HSCR3 | glial cell derived neurotrophic factor |
| TCMBANKGE000637 | SDHB | CWS2; IP; PGL4; SDH; SDH1; SDH2; SDHIP | succinate dehydrogenase complex iron sulfur subunit B |
| TCMBANKGE013308 | SDHD | CBT1; CII-4; CWS3; PGL; PGL1; QPs3; SDH4; cybS | succinate dehydrogenase complex subunit D |
| TCMBANKGE001102 | MIR21 | MIRN21; hsa-mir-21; miR-21; miRNA21 | microRNA 21 |
| TCMBANKGE001045 | CCND1 | BCL1; D11S287E; PRAD1; U21B31 | cyclin D1 |
| TCMBANKGE002029 | EPAS1 | ECYT4; HIF2A; HLF; MOP2; PASD2; bHLHe73 | endothelial PAS domain protein 1 |
| TCMBANKGE012622 | SLC25A11 | OGC; PGL6; SLC20A4 | solute carrier family 25 member 11 |
| TCMBANKGE008393 | GRN | CLN11; GEP; GP88; PCDGF; PEPI; PGRN | granulin precursor |
| TCMBANKGE006425 | SLC26A4 | DFNB4; EVA; PDS; TDH2B | solute carrier family 26 member 4 |
| TCMBANKGE000601 | DCTN6 | WS-3; WS3; p27 | dynactin subunit 6 |
| TCMBANKGE000555 | SST | SMST | somatostatin |
| TCMBANKGE013931 | PPY | PNP; PP | pancreatic polypeptide |
| TCMBANKGE006516 | AIP | ARA9; FKBP16; FKBP37; PITA1; SMTPHN; XAP-2; XAP2 | aryl hydrocarbon receptor interacting protein |
| TCMBANKGE011480 | ISCU | 2310020H20Rik; HML; ISU2; NIFU; NIFUN; hnifU | iron-sulfur cluster assembly enzyme |
| TCMBANKGE000050 | MERTK | MER; RP38; Tyro12; c-Eyk; c-mer | MER proto-oncogene, tyrosine kinase |
| TCMBANKGE012196 | ATRX | JMS; MRX52; RAD54; RAD54L; XH2; XNP; ZNF-HX | ATRX chromatin remodeler |
| TCMBANKGE009252 | PNMT | PENT; PNMTase | phenylethanolamine N-methyltransferase |
| TCMBANKGE005091 | MAX | bHLHd4 | MYC associated factor X |
| TCMBANKGE000599 | H3P23 | p27 | H3 histone pseudogene 23 |
| TCMBANKGE003865 | SORD | HEL-S-95n; RDH; SDH; SORD1; XDH | sorbitol dehydrogenase |
| TCMBANKGE007770 | PHOX2B | CCHS; NBLST2; NBPhox; PMX2B | paired like homeobox 2B |
| TCMBANKGE014757 | IDH2 | D2HGA2; ICD-M; IDH; IDHM; IDP; IDPM; mNADP-IDH | isocitrate dehydrogenase (NADP(+)) 2 |
| TCMBANKGE002526 | BAP1 | HUCEP-13; UCHL2; hucep-6 | BRCA1 associated protein 1 |
| TCMBANKGE000771 | TWIST1 | ACS3; BPES2; BPES3; CRS; CRS1; CSO; SCS; SWCOS; TWIST; bHLHa38 | twist family bHLH transcription factor 1 |
| TCMBANKGE012329 | AGRP | AGRT; ART; ASIP2 | agouti related neuropeptide |
| TCMBANKGE000639 | HRAS | C-BAS/HAS; C-H-RAS; C-HA-RAS1; CTLO; H-RASIDX; HAMSV; HRAS1; RASH1; p21ras | HRas proto-oncogene, GTPase |
| TCMBANKGE000684 | EGLN1 | C1orf12; ECYT3; HALAH; HIF-PH2; HIFPH2; HPH-2; HPH2; PHD2; SM20; ZMYND6 | egl-9 family hypoxia inducible factor 1 |
| TCMBANKGE003672 | CALM1 | CALML2; CAM2; CAM3; CAMB; CAMC; CAMI; CAMIII; CPVT4; DD132; LQT14; PHKD; caM | calmodulin 1 |
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