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疾病ID:TCMBANKDI030891

疾病名:Cocaine-Related Disorders

MeSH_Name:Chemically-Induced Disorders; Mental Disorders

HPO_Name:-

UMLS_Name:Mental or Behavioral Dysfunction

DO_Name:disease of mental health

疾病类型:group

DisGeNET_Link:C0236736

MeSH_Link:C25; F03

HPO_Link:-

UMLS_Link:T048

DO_Link:DOID:150

HERB_ID:-

   疾病对应的植物
ID 拉丁名 药名 药用植物名 功能与主治 来源 药用部位 使用民族
   疾病对应的化合物
化合物ID 化合物名 别名 分子式 分子质量 Smiles
TCMBANKIN000030 cocaine (-)Cocaine; 2alpha-Carbomethoxy-3beta-(benzoyloxy)tropane; 8-Azabicyclo[3.2.1]octane-2-carboxylic acid, 3-(benzoyloxy)-8-methyl-, methyl ester, (1R,2R,3S,5S)-; 1alphaH,5alphaH-Tropane-2beta-carboxylic acid, 3beta-hydroxy-, methyl ester, benzoate (ester); Ecgonine methyl ester benzoate (ester) C17H21NO4 303.35 g/mol CN1C2CCC1C(C(C2)OC(=O)C3=CC=CC=C3)C(=O)OC
   疾病对应的靶点
靶点ID 基因名 基因别名 描述
TCMBANKGE003584 HCRTR1 OX1R hypocretin receptor 1
TCMBANKGE000259 SCARB1 CD36L1; CLA-1; CLA1; HDLQTL6; SR-BI; SRB1 scavenger receptor class B member 1
TCMBANKGE012410 ARC Arg3.1; hArc activity regulated cytoskeleton associated protein
TCMBANKGE001180 SMAD3 HSPC193; HsT17436; JV15-2; LDS1C; LDS3; MADH3 SMAD family member 3
TCMBANKGE000235 NTRK2 EIEE58; GP145-TrkB; OBHD; TRKB; trk-B neurotrophic receptor tyrosine kinase 2
TCMBANKGE009304 FDFT1 DGPT; ERG9; SQS; SQSD; SS farnesyl-diphosphate farnesyltransferase 1
TCMBANKGE005480 KLHL5 - kelch like family member 5
TCMBANKGE011295 MANEA ENDO; hEndo mannosidase endo-alpha
TCMBANKGE006517 SLC1A2 EAAT2; EIEE41; GLT-1; HBGT solute carrier family 1 member 2
TCMBANKGE014015 BCHE BCHED; CHE1; CHE2; E1 butyrylcholinesterase
TCMBANKGE001197 FOS AP-1; C-FOS; p55 Fos proto-oncogene, AP-1 transcription factor subunit
TCMBANKGE006911 GABRA2 EIEE78 gamma-aminobutyric acid type A receptor subunit alpha2
TCMBANKGE011654 NPS - neuropeptide S
TCMBANKGE009455 CHRM5 HM5 cholinergic receptor muscarinic 5
TCMBANKGE008011 HTR2A 5-HT2A; HTR2 5-hydroxytryptamine receptor 2A
TCMBANKGE011040 TACR3 HH11; NK-3R; NK3; NK3R; NKR; TAC3R; TAC3RL tachykinin receptor 3
TCMBANKGE000362 DNAH8 ATPase; hdhc9 dynein axonemal heavy chain 8
TCMBANKGE002926 SNCG BCSG1; SR synuclein gamma
TCMBANKGE004151 PRL GHA1 prolactin
TCMBANKGE009922 GABRG2 CAE2; ECA2; EIEE74; FEB8; GEFSP3 gamma-aminobutyric acid type A receptor subunit gamma2
TCMBANKGE000311 JUND AP-1 JunD proto-oncogene, AP-1 transcription factor subunit
TCMBANKGE003079 CCKBR CCK-B; CCK2R; GASR cholecystokinin B receptor
TCMBANKGE004499 HOMER2 ACPD; CPD; DFNA68; HOMER-2; VESL-2 homer scaffold protein 2
TCMBANKGE001191 GRIA1 GLUH1; GLUR1; GLURA; GluA1; HBGR1 glutamate ionotropic receptor AMPA type subunit 1
TCMBANKGE005865 CAMK4 CaMK IV; CaMK-GR; CaMKIV; caMK calcium/calmodulin dependent protein kinase IV
TCMBANKGE012438 NPY2R NPY2-R neuropeptide Y receptor Y2
TCMBANKGE001136 MECP2 AUTSX3; MRX16; MRX79; MRXS13; MRXSL; PPMX; RS; RTS; RTT methyl-CpG binding protein 2
TCMBANKGE000701 ESR2 ER-BETA; ESR-BETA; ESRB; ESTRB; Erb; NR3A2; ODG8 estrogen receptor 2
TCMBANKGE001192 HCRT NRCLP1; OX; PPOX hypocretin neuropeptide precursor
TCMBANKGE000060 CRHR1 CRF-R; CRF-R-1; CRF-R1; CRF1; CRFR-1; CRFR1; CRH-R-1; CRH-R1; CRHR; CRHR1L corticotropin releasing hormone receptor 1
TCMBANKGE007865 LRRC7 DENSIN leucine rich repeat containing 7
TCMBANKGE012171 GABBR1 GABABR1; GABBR1-3; GB1; GPRC3A gamma-aminobutyric acid type B receptor subunit 1
TCMBANKGE000258 EGR1 AT225; G0S30; KROX-24; NGFI-A; TIS8; ZIF-268; ZNF225 early growth response 1
TCMBANKGE001203 MAPK1 ERK; ERK-2; ERK2; ERT1; MAPK2; P42MAPK; PRKM1; PRKM2; p38; p40; p41; p41mapk; p42-MAPK mitogen-activated protein kinase 1
TCMBANKGE003056 GAD2 GAD65 glutamate decarboxylase 2
TCMBANKGE012155 SLC6A3 DAT; DAT1; PKDYS; PKDYS1 solute carrier family 6 member 3
TCMBANKGE000168 NR3C1 GCCR; GCR; GCRST; GR; GRL nuclear receptor subfamily 3 group C member 1
TCMBANKGE005288 PDYN ADCA; PENKB; SCA23 prodynorphin
TCMBANKGE000212 GRIN1 GluN1; MRD8; NDHMSD; NDHMSR; NMD-R1; NMDA1; NMDAR1; NR1 glutamate ionotropic receptor NMDA type subunit 1
TCMBANKGE004751 GPHN GEPH; GPH; GPHRYN; HKPX1; MOCODC gephyrin
TCMBANKGE000974 SMAD5 DWFC; JV5-1; MADH5 SMAD family member 5
TCMBANKGE006565 NPY PYY4 neuropeptide Y
TCMBANKGE014869 HTR1B 5-HT-1B; 5-HT-1D-beta; 5-HT1B; 5-HT1DB; HTR1D2; HTR1DB; S12 5-hydroxytryptamine receptor 1B
TCMBANKGE001582 CAMK2B CAM2; CAMK2; CAMKB; CaMKIIbeta; MRD54 calcium/calmodulin dependent protein kinase II beta
TCMBANKGE000202 RUNX2 AML3; CBF-alpha-1; CBFA1; CCD; CCD1; CLCD; OSF-2; OSF2; PEA2aA; PEBP2aA RUNX family transcription factor 2
TCMBANKGE001231 CRHBP CRF-BP; CRFBP corticotropin releasing hormone binding protein
TCMBANKGE000966 SIGMAR1 ALS16; DSMA2; OPRS1; SIG-1R; SR-BP; SR-BP1; SRBP; hSigmaR1; sigma1R sigma non-opioid intracellular receptor 1
TCMBANKGE001154 CREB1 CREB; CREB-1 cAMP responsive element binding protein 1
TCMBANKGE003724 PRMT6 HRMT1L6 protein arginine methyltransferase 6
TCMBANKGE008743 OPRK1 K-OR-1; KOP; KOR; KOR-1; KOR1; OPRK opioid receptor kappa 1
TCMBANKGE000221 GRIA2 GLUR2; GLURB; GluA2; GluR-K2; HBGR2; gluR-2; gluR-B glutamate ionotropic receptor AMPA type subunit 2
TCMBANKGE001230 HOMER1 HOMER; HOMER1A; HOMER1B; HOMER1C; SYN47; Ves-1 homer scaffold protein 1
TCMBANKGE007113 HDAC4 AHO3; BDMR; HA6116; HD4; HDAC-4; HDAC-A; HDACA histone deacetylase 4
TCMBANKGE002445 GHRL MTLRP ghrelin and obestatin prepropeptide
TCMBANKGE008702 OPRM1 LMOR; M-OR-1; MOP; MOR; MOR1; OPRM opioid receptor mu 1
TCMBANKGE000158 RHOA ARH12; ARHA; EDFAOB; RHO12; RHOH12 ras homolog family member A
TCMBANKGE012345 DRD3 D3DR; ETM1; FET1 dopamine receptor D3
TCMBANKGE000471 POMC ACTH; CLIP; LPH; MSH; NPP; OBAIRH; POC proopiomelanocortin
TCMBANKGE003418 GRM5 GPRC1E; MGLUR5; PPP1R86; mGlu5 glutamate metabotropic receptor 5
TCMBANKGE011882 EHMT2 BAT8; C6orf30; G9A; GAT8; KMT1C; NG36 euchromatic histone lysine methyltransferase 2
TCMBANKGE000310 FOSB AP-1; G0S3; GOS3; GOSB FosB proto-oncogene, AP-1 transcription factor subunit
TCMBANKGE012945 RPS6KA5 MSK1; MSPK1; RLPK ribosomal protein S6 kinase A5
TCMBANKGE001455 CARTPT CART CART prepropeptide
TCMBANKGE000022 CAMK2A CAMKA; CaMKIINalpha; CaMKIIalpha; MRD53; MRT63 calcium/calmodulin dependent protein kinase II alpha
TCMBANKGE011342 NGF Beta-NGF; HSAN5; NGFB nerve growth factor
TCMBANKGE000590 ILK HEL-S-28; ILK-1; ILK-2; P59; p59ILK integrin linked kinase
TCMBANKGE003602 CES2 CE-2; CES2A1; PCE-2; iCE carboxylesterase 2
TCMBANKGE008417 GPSM1 AGS3 G protein signaling modulator 1
TCMBANKGE000251 FGF2 BFGF; FGF-2; FGFB; HBGF-2 fibroblast growth factor 2
TCMBANKGE000398 MIR137 MIRN137; miR-137 microRNA 137
TCMBANKGE001004 MIR301B MIRN301B; mir-301b microRNA 301b
TCMBANKGE002550 NPSR1 ASRT2; GPR154; GPRA; NPSR; PGR14; VRR1 neuropeptide S receptor 1
TCMBANKGE007850 CFL1 CFL; HEL-S-15; cofilin cofilin 1
TCMBANKGE000977 SMAD1 BSP-1; BSP1; JV4-1; JV41; MADH1; MADR1 SMAD family member 1
TCMBANKGE001193 GDNF ATF; ATF1; ATF2; HFB1-GDNF; HSCR3 glial cell derived neurotrophic factor
TCMBANKGE001201 MAPK3 ERK-1; ERK1; ERT2; HS44KDAP; HUMKER1A; P44ERK1; P44MAPK; PRKM3; p44-ERK1; p44-MAPK mitogen-activated protein kinase 3
TCMBANKGE014932 COMT HEL-S-98n catechol-O-methyltransferase
TCMBANKGE000801 HTR1A 5-HT-1A; 5-HT1A; 5HT1a; ADRB2RL1; ADRBRL1; G-21; PFMCD 5-hydroxytryptamine receptor 1A
TCMBANKGE014473 CRH CRF; CRH1 corticotropin releasing hormone
TCMBANKGE009407 TYK2 IMD35; JTK1 tyrosine kinase 2
TCMBANKGE001313 SMURF1 - SMAD specific E3 ubiquitin protein ligase 1
TCMBANKGE000869 DRD2 D2DR; D2R dopamine receptor D2
TCMBANKGE001001 SNCA NACP; PARK1; PARK4; PD1 synuclein alpha
TCMBANKGE003625 SLC6A4 5-HTT; 5-HTTLPR; 5HTT; HTT; OCD1; SERT; SERT1; hSERT solute carrier family 6 member 4
TCMBANKGE012559 CRHR2 CRF-RB; CRF2; CRFR2; HM-CRF corticotropin releasing hormone receptor 2
TCMBANKGE000425 DRD1 DADR; DRD1A dopamine receptor D1
TCMBANKGE000236 BDNF ANON2; BULN2 brain derived neurotrophic factor
TCMBANKGE000514 CNR1 CANN6; CB-R; CB1; CB1A; CB1K5; CB1R; CNR cannabinoid receptor 1
TCMBANKGE014656 ABAT GABA-AT; GABAT; NPD009 4-aminobutyrate aminotransferase
TCMBANKGE002612 HDAC5 HD5; NY-CO-9 histone deacetylase 5
TCMBANKGE005717 COL21A1 COLA1L; FP633 collagen type XXI alpha 1 chain
TCMBANKGE014746 CES1 ACAT; CE-1; CEH; CES2; HMSE; HMSE1; PCE-1; REH; SES1; TGH; hCE-1 carboxylesterase 1
TCMBANKGE000557 ATP9B ATPASEP; ATPIIB; HUSSY-20; NEO1L; hMMR1 ATPase phospholipid transporting 9B (putative)
TCMBANKGE003672 CALM1 CALML2; CAM2; CAM3; CAMB; CAMC; CAMI; CAMIII; CPVT4; DD132; LQT14; PHKD; caM calmodulin 1
TCMBANKGE000054 GAD1 CPSQ1; GAD; SCP glutamate decarboxylase 1

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