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疾病ID:TCMBANKDI032433
疾病名:Learning Disabilities
MeSH_Name:Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders
HPO_Name:-
UMLS_Name:Mental or Behavioral Dysfunction
DO_Name:disease of mental health
疾病类型:disease
DisGeNET_Link:C0751265
MeSH_Link:C23; C10; F03
HPO_Link:-
UMLS_Link:T048
DO_Link:DOID:150
HERB_ID:-
疾病对应的植物
| ID | 拉丁名 | 药名 | 药用植物名 | 功能与主治 | 来源 | 药用部位 | 使用民族 |
|---|
疾病对应的化合物
| 化合物ID | 化合物名 | 别名 | 分子式 | 分子质量 | Smiles |
|---|
| TCMBANKIN058519 | (-)-epigallocatechin-3-gallate; (-)-epigallocatechin 3-o-gallate;epigallocatechin gallate; galloyl-l-epigallocatechol; epigallocatechin 3-gallate; (-)-epigallocatechin gallate; | KBio2_000796; SpecPlus_000277; 50299_FLUKA; Spectrum3_000244; KBioGR_002002; 3,4,5-trihydroxybenzoic acid [(2R,3R)-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)chroman-3-yl] ester; MLS000758300; DivK1c_006373; (−)-Epigallocatechin gallate; EGCG; SPBio_000035; (−)-cis-2-(3,4,5-Trihydroxyphenyl)-3,4-dihydro-1(2H)-benzopyran-3,5,7-triol 3-gallate; KBioSS_000796; Epigallocatechin gallate; Spectrum4_001541; (-)-epigallocatechin 3-gallate; Tea catechin; AIDS000674; KBio2_005932; 3,4,5-trihydroxybenzoic acid [(2R,3R)-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-3-chromanyl] ester; KBio1_001317; 989-51-5; AIDS-000674; (2R,3R)-2-(3,4,5-Trihydroxyphenyl)-3,4-dihydro-1[2H]-benzopyran-3,5,7-triol-3-(3,4,5-trihydroxybenzoate); KBio2_003364; Galloyl-L-epigallocatechol; SDCCGMLS-0066550.P001; (-)-Epigallocatechol gallate; ACon1_001054; Spectrum5_000102; Green tea extract; MEGxp0_001166; C09731; (-)-Epigallocatechin-3-o-gallate; Epigallocatechin 3-gallate; (-)-Epigallocatechin gallate; CCRIS 3729; Teavigo; [(2R,3R)-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)chroman-3-yl] 3,4,5-trihydroxybenzoate; Spectrum2_000168; Benzoic acid, 3,4,5-trihydroxy-, (2R,3R)-3,4-dihydro-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-2H-1-benzopyran-3-yl ester; (−)-cis-3,3′,4′,5,5′,7-Hexahydroxy-flavane-3-gallate; CHEBI:4806; (-)-epigallocatechin-3-gallate ; (-)-Epigallocatechin gallate (85% (-)-epigallocatechin gallate, 10% (-)-epigallocatechin, 5% (-)- epicatechin gallate); Catechin deriv.; SMR000449288; SPECTRUM210239; E4143_SIAL; (2R,3R)-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-3,4-dihydro-2H-chromen-3-yl 3,4,5-trihydroxybenzoate; Spectrum_000316; (-)-EGCG; KBio3_001128; BSPBio_001628; Epigallocatechol, 3-gallate, (-)-; Epigallocatechin-3-gallate; E4268_SIAL; epigallocatechin gallate ; epigallocatechin-3-gallate; (-)epigallocatechin-3-gallate ; EGCG; 989E515; [5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)chroman-3-yl] 2,3,4-trihydroxybenzoate; HMS2051K21; CS-1258; AC1L22IG; AK165605; Green tea polyphenols, Anagen; (-)-Epigallocatechin-3-O-gallate, United States Pharmacopeia (USP) Reference Standard; AKOS015918182; CAS-989-51-5; Epigallocatechin gallate, primary pharmaceutical reference standard; W-5069; (-)-cis-3,3',4',5,5',7-Hexahydroxy-flavane-3-gallate; (-)-Epigallocatechin gallate, analytical standard; Q-100914; DSSTox_RID_78830; AN-15867; DSSTox_GSID_29889; (-)-Epigallocatechol gallate; FT-0604392; NCGC00164319-04; Green tea extract; MEGxp0_001166; (-)-Epigallocatechin-3-o-gallate; Epigallocatechin 3-gallate; N1874; CHEBI:4806; (2R,3R)-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-3,4-dihydro-2H-chromen-3-yl 3,4,5-trihydroxybenzoate; BG00814299; HMS3649E08; D0E9DB; Epigallocatechol, 3-gallate, (-)-; (-)-EpigallocatechinGallateHydrate; Epigallocatechin-3-gallate; AB0014381; BQM438CTEL; NC00078; ST51055716; Epigallocatechin gallate, Pharmaceutical Secondary Standard; Certified Reference Material; SpecPlus_000277; Spectrum3_000244; (2R,3R)-5,7-Dihydroxy-2-(3,4,5-trihydroxyphenyl)-3,4-dihydro-2H-chromen-3-yl-3,4,5-trihydroxybenzoate; MLS000758300; (-)-Epigallocatechin gallate (EGCG); CCG-38378; Gallic acid, 3-ester with epigallocatechol, (-)-; SR-01000946601-1; NCGC00164319-01; (-)-cis-3,4-Dihydro-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-1(2H)-benzopyran-3-yl Gallate; NCGC00164319-06; DSSTox_CID_567; MCULE-3341525983; Epigallocatechin monogallate, B; Tox21_303457; SAM001247031; 4awm; K791; 989-51-5; SR-01000946601; MFCD00075940; EGCG analogs; Galloyl-L-epigallocatechol; NCGC00164319-03; (-)-Epigallocatechin gallate, >=80% (HPLC), from green tea; Spectrum5_000102; CPD000449288; (-)-Epigallocatechin gallate; LMPK12030005; E0694; Teavigo; Epigallocatechin gallate analogs, Anagen; Epigallocatechin-3-monogallate; ACN-035233; Benzoic acid, 3,4,5-trihydroxy-, (2R,3R)-3,4-dihydro-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-2H-1-benzopyran-3-yl ester; Sunphenon; Epigallocatechin gallate(EGCG); s2250; PF-EGCg 90; 3,4-Dihydro-5,7-dihydroxy-2R-(3,4,5-trihydroxyphenyl)-2H-1-benzopyran-3R-yl-3,4,5-trihydroxybenzoate; 3,4,5-Trihydroxybenzoic acid (2R,3R)-3,4-dihydro-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-2H-1-benzopyran-3-yl ester; MLS001424000; (-)-EGCG; ZINC3870412; KBio2_000796; EGCG cpd; KBioGR_002002; Benzoic acid, 3,4,5-trihydroxy-, 3,4-dihydro-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-2H-1-benzopyran-3-yl ester, (2R-cis)-; EGCG, Anagen; NCGC00257243-01; Tox21_201468; L-Epigallocatechin gallate; cid_65064; SPBio_000035; BG01747388; Epigallocatechin gallate; KBioSS_000796; Spectrum4_001541; (-)-epigallocatechin 3-gallate; DB12116; EPIGALOCATECHIN GALLATE; ANTIOXIDANT MODEL (TRAMP) -EPIGALLOCATECHIN GALLATE; KBio2_005932; I14-7747; D0U2BH; MCULE-7760530136; 2kdh; Epigallocatechin gallate, Anagen; AOB2839; SDCCGMLS-0066550.P001; 863-65-0; FR-109; ST097428; ACon1_001054; LS-2197; CCRIS 3729; [(2R,3R)-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)chroman-3-yl] 3,4,5-trihydroxybenzoate; Epigallocate; GTPL7002; BDBM50070942; C22H18O11; GTPs,Anagen; SCHEMBL35258; (2R,3R)-5,7-Dihydroxy-2-(3,4,5-trihydroxyphenyl)chroman-3-yl 3,4,5-trihydroxybenzoate; MolPort-001-741-358; DivK1c_006373; KB-206444; SR-01000759328; Teavigo;; EGCG; (-)-EPIGALLOCATECHIN GALLATE (GREEN TEA EXTRACT); HY-13653; (-)-Epigallocatechin gallate, >=95%; NCGC00259019-01; Tea catechin; DS-9030; SR-01000759328-6; SR-01000759328-5; KDH; AC1Q5X0Z; KBio1_001317; (2R,3R)-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)chroman-3-yl 3,4,5-trihydroxyb enzoate; (2R,3R)-2-(3,4,5-Trihydroxyphenyl)-3,4-dihydro-1[2H]-benzopyran-3,5,7-triol-3-(3,4,5-trihydroxybenzoate); NVP-XAA 723; KBio2_003364; EBD2138593; FT-0082796; NCGC00164319-02; C09731; (-)-cis-2-(3,4,5-Trihydroxyphenyl)-3,4-dihydro-1(2H)-benzopyran-3,5,7-triol 3-gallate; UNII-BQM438CTEL; DTXSID1029889; WMBWREPUVVBILR-WIYYLYMNSA-N; [(2R,3R)-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-3,4-dihydro-2H-chromen-3-yl] 3,4,5-trihydroxybenzoate; (-)-Epigallocatehin gallate; Spectrum2_000168; (2R,3R)-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-3,4-dihydro-2H-1-benzopyran-3-yl 3,4,5-trihydroxybenzoate; (-)-Epigallocatechin gallate (85% (-)-epigallocatechin gallate, 10% (-)-epigallocatechin, 5% (-)- epicatechin gallate); Catechin deriv.; SMR000449288; (-)-Epigallocatechin gallat; SPECTRUM210239; Epigallocic acid; Epigallocatcchin Gallate; KS-0000132O; BP-30205; CHEMBL297453; SC-47284; Spectrum_000316; 3oob; (-)-Epigallocatechin gallate, >=97.0% (HPLC); KBio3_001128; BSPBio_001628; epigallo-catechin gallate | C22H18O11 | 458.4g/mol | C1C(C(OC2=CC(=CC(=C21)O)O)C3=CC(=C(C(=C3)O)O)O)OC(=O)C4=CC(=C(C(=C4)O)O)O |
疾病对应的靶点
| 靶点ID | 基因名 | 基因别名 | 描述 |
|---|
| TCMBANKGE007046 | AP2S1 | AP17; CLAPS2; FBH3; FBHOk; HHC3 | adaptor related protein complex 2 subunit sigma 1 |
| TCMBANKGE006559 | GYPA | CD235a; GPA; GPErik; GPSAT; HGpMiV; HGpMiXI; HGpSta(C); MN; MNS; PAS-2 | glycophorin A (MNS blood group) |
| TCMBANKGE011168 | TCF12 | CRS3; HEB; HTF4; HsT17266; TCF-12; bHLHb20; p64 | transcription factor 12 |
| TCMBANKGE005547 | PPL | - | periplakin |
| TCMBANKGE008479 | PICALM | CALM; CLTH; LAP | phosphatidylinositol binding clathrin assembly protein |
| TCMBANKGE000447 | TSC2 | LAM; PPP1R160; TSC4 | TSC complex subunit 2 |
| TCMBANKGE003153 | DMD | BMD; CMD3B; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272; MRX85 | dystrophin |
| TCMBANKGE010585 | MICU1 | CALC; CBARA1; EFHA3; MPXPS; ara CALC | mitochondrial calcium uptake 1 |
| TCMBANKGE003401 | APOD | - | apolipoprotein D |
| TCMBANKGE009265 | MEIS2 | CPCMR; HsT18361; MRG1 | Meis homeobox 2 |
| TCMBANKGE013383 | VCP | CDC48; TERA; p97 | valosin containing protein |
| TCMBANKGE014985 | PTH | FIH1; PTH1 | parathyroid hormone |
| TCMBANKGE001191 | GRIA1 | GLUH1; GLUR1; GLURA; GluA1; HBGR1 | glutamate ionotropic receptor AMPA type subunit 1 |
| TCMBANKGE003296 | PHB2 | BAP; BCAP37; Bap37; PNAS-141; REA; hBAP; p22 | prohibitin 2 |
| TCMBANKGE001136 | MECP2 | AUTSX3; MRX16; MRX79; MRXS13; MRXSL; PPMX; RS; RTS; RTT | methyl-CpG binding protein 2 |
| TCMBANKGE013591 | PNOC | N/OFQ; NOP; OFQ; PPNOC; ppN/OFQ | prepronociceptin |
| TCMBANKGE004197 | IQSEC2 | BRAG1; IQ-ArfGEF; MRX1; MRX18; MRX78 | IQ motif and Sec7 domain ArfGEF 2 |
| TCMBANKGE004021 | FMR1 | FMRP; FRAXA; POF; POF1 | FMRP translational regulator 1 |
| TCMBANKGE008056 | ADRA2C | ADRA2L2; ADRA2RL2; ADRARL2; ALPHA2CAR | adrenoceptor alpha 2C |
| TCMBANKGE014077 | PURA | MRD31; PUR-ALPHA; PUR1; PURALPHA | purine rich element binding protein A |
| TCMBANKGE004056 | PANK2 | C20orf48; HARP; HSS; NBIA1; PKAN | pantothenate kinase 2 |
| TCMBANKGE010269 | RANGAP1 | Fug1; RANGAP; SD | Ran GTPase activating protein 1 |
| TCMBANKGE006135 | CDH8 | Nbla04261 | cadherin 8 |
| TCMBANKGE006914 | DCDC2 | DCDC2A; DFNB66; NPHP19; NSC; RU2; RU2S | doublecortin domain containing 2 |
| TCMBANKGE001690 | HADHB | ECHB; MSTP029; MTPB; TP-BETA | hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta |
| TCMBANKGE001339 | ALDH5A1 | SSADH; SSDH | aldehyde dehydrogenase 5 family member A1 |
| TCMBANKGE011125 | ZIC1 | BAIDCS; CRS6; ZIC; ZNF201 | Zic family member 1 |
| TCMBANKGE014169 | CACNA1G | Ca(V)T.1; Cav3.1; NBR13; SCA42; SCA42ND | calcium voltage-gated channel subunit alpha1 G |
| TCMBANKGE006490 | DCTN3 | DCTN-22; DCTN22 | dynactin subunit 3 |
| TCMBANKGE000017 | MAPT | DDPAC; FTDP-17; MAPTL; MSTD; MTBT1; MTBT2; PPND; PPP1R103; TAU | microtubule associated protein tau |
| TCMBANKGE011312 | FIBP | FGFIBP; FIBP-1; TROFAS | FGF1 intracellular binding protein |
| TCMBANKGE008465 | NIPBL | CDLS; CDLS1; IDN3; IDN3-B; Scc2 | NIPBL cohesin loading factor |
| TCMBANKGE012999 | CHP1 | CHP; SLC9A1BP; SPAX9; Sid470p; p22; p24 | calcineurin like EF-hand protein 1 |
| TCMBANKGE002137 | PSEN1 | ACNINV3; AD3; FAD; PS-1; PS1; S182 | presenilin 1 |
| TCMBANKGE010497 | CITED2 | ASD8; MRG-1; MRG1; P35SRJ; VSD2 | Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2 |
| TCMBANKGE002699 | TH | DYT14; DYT5b; TYH | tyrosine hydroxylase |
| TCMBANKGE005229 | DPP6 | DPL1; DPPX; MRD33; VF2 | dipeptidyl peptidase like 6 |
| TCMBANKGE000966 | SIGMAR1 | ALS16; DSMA2; OPRS1; SIG-1R; SR-BP; SR-BP1; SRBP; hSigmaR1; sigma1R | sigma non-opioid intracellular receptor 1 |
| TCMBANKGE002043 | CTNND2 | GT24; NPRAP | catenin delta 2 |
| TCMBANKGE011870 | RABL6 | C9orf86; PARF; RBEL1; pp8875 | RAB, member RAS oncogene family like 6 |
| TCMBANKGE013306 | NPAS3 | MOP6; PASD6; bHLHe12 | neuronal PAS domain protein 3 |
| TCMBANKGE010402 | NF1 | NFNS; VRNF; WSS | neurofibromin 1 |
| TCMBANKGE009241 | TRRAP | DEDDFA; DFNA75; PAF350/400; PAF400; STAF40; TR-AP; Tra1 | transformation/transcription domain associated protein |
| TCMBANKGE009848 | ARSD | ASD | arylsulfatase D |
| TCMBANKGE000784 | CALM3 | CALM; CAM1; CAM2; CAMB; CPVT6; CaM; CaMIII; HEL-S-72; LQT16; PHKD; PHKD3 | calmodulin 3 |
| TCMBANKGE000139 | POR | CPR; CYPOR; P450R | cytochrome p450 oxidoreductase |
| TCMBANKGE000301 | SLC2A1 | CSE; DYT17; DYT18; DYT9; EIG12; GLUT; GLUT-1; GLUT1; GLUT1DS; HTLVR; PED; SDCHCN | solute carrier family 2 member 1 |
| TCMBANKGE000766 | ACHE | ACEE; ARACHE; N-ACHE; YT | acetylcholinesterase (Cartwright blood group) |
| TCMBANKGE010086 | LRFN2 | FIGLER2; KIAA1246; SALM1 | leucine rich repeat and fibronectin type III domain containing 2 |
| TCMBANKGE000465 | CASR | CAR; EIG8; FHH; FIH; GPRC2A; HHC; HHC1; HYPOC1; NSHPT; PCAR1; hCasR | calcium sensing receptor |
| TCMBANKGE013309 | SLC17A7 | BNPI; VGLUT1 | solute carrier family 17 member 7 |
| TCMBANKGE005925 | TRIP12 | MRD49; TRIP-12; TRIPC; ULF | thyroid hormone receptor interactor 12 |
| TCMBANKGE005556 | CAMKMT | C2orf34; CLNMT; CaM KMT; Cam; KMT | calmodulin-lysine N-methyltransferase |
| TCMBANKGE013469 | FOXP2 | CAGH44; SPCH1; TNRC10 | forkhead box P2 |
| TCMBANKGE000811 | KL | HFTC3 | klotho |
| TCMBANKGE000835 | APP | AAA; ABETA; ABPP; AD1; APPI; CTFgamma; CVAP; PN-II; PN2; preA4 | amyloid beta precursor protein |
| TCMBANKGE002680 | SCO2 | CEMCOX1; ECGF1; Gliostatin; MYP6; PD-ECGF; SCO1L; TP; TYMP; TdRPase | synthesis of cytochrome C oxidase 2 |
| TCMBANKGE007459 | DBH | DBM; ORTHYP1 | dopamine beta-hydroxylase |
| TCMBANKGE001194 | ADRA2A | ADRA2; ADRA2R; ADRAR; ALPHA2AAR; ZNF32 | adrenoceptor alpha 2A |
| TCMBANKGE010271 | NHS | CTRCT40; CXN; SCML1 | NHS actin remodeling regulator |
| TCMBANKGE000690 | SYP | MRX96; MRXSYP | synaptophysin |
| TCMBANKGE013113 | NLGN4X | ASPGX2; AUTSX2; HLNX; HNL4X; NLGN4 | neuroligin 4 X-linked |
| TCMBANKGE011468 | DLG4 | MRD62; PSD95; SAP-90; SAP90 | discs large MAGUK scaffold protein 4 |
| TCMBANKGE006621 | YWHAE | 14-3-3E; HEL2; KCIP-1; MDCR; MDS | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon |
| TCMBANKGE015037 | TSC1 | LAM; TSC | TSC complex subunit 1 |
| TCMBANKGE007543 | INSR | CD220; HHF5 | insulin receptor |
| TCMBANKGE001096 | TLR4 | ARMD10; CD284; TLR-4; TOLL | toll like receptor 4 |
| TCMBANKGE001201 | MAPK3 | ERK-1; ERK1; ERT2; HS44KDAP; HUMKER1A; P44ERK1; P44MAPK; PRKM3; p44-ERK1; p44-MAPK | mitogen-activated protein kinase 3 |
| TCMBANKGE011803 | HTR7 | 5-HT7 | 5-hydroxytryptamine receptor 7 |
| TCMBANKGE000801 | HTR1A | 5-HT-1A; 5-HT1A; 5HT1a; ADRB2RL1; ADRBRL1; G-21; PFMCD | 5-hydroxytryptamine receptor 1A |
| TCMBANKGE000330 | HMOX1 | HMOX1D; HO-1; HSP32; bK286B10 | heme oxygenase 1 |
| TCMBANKGE013754 | TRH | Pro-TRH; TRF | thyrotropin releasing hormone |
| TCMBANKGE006028 | ALX3 | FND; FND1 | ALX homeobox 3 |
| TCMBANKGE003625 | SLC6A4 | 5-HTT; 5-HTTLPR; 5HTT; HTT; OCD1; SERT; SERT1; hSERT | solute carrier family 6 member 4 |
| TCMBANKGE013956 | DYNC1H1 | CMT2O; DHC1; DHC1a; DNCH1; DNCL; DNECL; DYHC; Dnchc1; HL-3; SMALED1; p22 | dynein cytoplasmic 1 heavy chain 1 |
| TCMBANKGE010998 | TBL1XR1 | C21; DC42; IRA1; MRD41; TBLR1 | TBL1X receptor 1 |
| TCMBANKGE000612 | IQCB1 | NPHP5; PIQ; SLSN5 | IQ motif containing B1 |
| TCMBANKGE000771 | TWIST1 | ACS3; BPES2; BPES3; CRS; CRS1; CSO; SCS; SWCOS; TWIST; bHLHa38 | twist family bHLH transcription factor 1 |
| TCMBANKGE006010 | RETN | ADSF; FIZZ3; RETN1; RSTN; XCP1 | resistin |
| TCMBANKGE000075 | IL1RN | DIRA; ICIL-1RA; IL-1RN; IL-1ra; IL-1ra3; IL1F3; IL1RA; IRAP; MVCD4 | interleukin 1 receptor antagonist |
| TCMBANKGE000712 | COL1A1 | CAFYD; EDSARTH1; EDSC; OI1; OI2; OI3; OI4 | collagen type I alpha 1 chain |
| TCMBANKGE003672 | CALM1 | CALML2; CAM2; CAM3; CAMB; CAMC; CAMI; CAMIII; CPVT4; DD132; LQT14; PHKD; caM | calmodulin 1 |
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