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CTSK

靶点ID:TCMBANKGE000680

靶点别名:CTS02; CTSO; CTSO1; CTSO2; PKND; PYCD

靶点描述:cathepsin K

染色体:1

染色体位置:1q21.3

靶点类型:protein-coding

HERB_ID:-

HGNC_Link:2536

OMIM_Link:601105

Ensembl_Link:ENSG00000143387

靶点对应的植物

ID	拉丁名	药名	药用植物名	功能与主治	来源	药用部位	使用民族

TCMBANKHE003718	Flos Chrysanthemi		菊花	To dispel wind-heat, to subdue hyperactivity of the liver, and improve eyesight./Angina pectoris, hypertension, externally contracted wind-heat, wind warmth, fever and headache, dizziness, common cold, red eyes, red eyes with gall, swelling toxin of clove sore.		capitulum
TCMBANKHE003751/YEM-812	Prunus armeniaca\|Prunus armeniaca L.	杏仁	杏仁\|杏	To downbear qi and transform phlegm, relieve cough and calm asthma, moisten intestines and free stool./Cough, asthma and fullness due to external contraction cough, intestinal dry and constipation.	云南民族药物志：第四卷	bitter seed	回族/傈僳族/彝族/藏族
TCMBANKHE005793	Flos Chrysanthemi		菊花	To dispel wind-heat, to subdue hyperactivity of the liver, and improve eyesight./Angina pectoris, hypertension, externally contracted wind-heat, wind warmth, fever and headache, dizziness, common cold, red eyes, red eyes with gall, swelling toxin of clove sore.		capitulum

靶点对应的化合物

化合物ID	化合物名	别名	分子式	分子质量	Smiles

TCMBANKIN000065	dioscin	LMST01080053; C08897; 3-O-(Rhaa1-4(Rhaa1-2)Glcb)-(25R)-spirost-5-en-3beta-ol; dioscin ; 19057-60-4; Dioscin	C45H72O16	869.04	CC1CCC2(C(C3C(O2)CC4C3(CCC5C4CC=C6C5(CCC(C6)OC7C(C(C(C(O7)CO)OC8C(C(C(C(O8)C)O)O)O)O)OC9C(C(C(C(O9)C)O)O)O)C)C)C)OC1
TCMBANKIN002984	Militarin_qt		C34H46O17	726.72
TCMBANKIN024826	protease				CC(C)CC(C(=O)NCCCCN=C(N)N)NC(=O)C1C(O1)C(=O)O
TCMBANKIN059452	ethyl aldehyde		C2H4O	44.05 g/mol	CC=O
TCMBANKIN060497	dioscin		C45H72O16	869.04	CC1CCC2(C(C3C(O2)CC4C3(CCC5C4CC=C6C5(CCC(C6)OC7C(C(C(C(O7)CO)OC8C(C(C(C(O8)C)O)O)O)O)OC9C(C(C(C(O9)C)O)O)O)C)C)C)OC1

靶点对应的疾病

疾病ID	疾病名	MeSH名	HPO名	UMLS名	疾病类型

TCMBANKDI000009	Neoplasms	Abnormality of the nervous system; Neoplasm	Neoplastic Process	disease
TCMBANKDI000023	Skin and Connective Tissue Diseases; Immune System Diseases	Abnormality of the immune system	Disease or Syndrome	disease
TCMBANKDI000054	Nervous System Diseases; Mental Disorders	Abnormality of the nervous system	Disease or Syndrome	disease
TCMBANKDI000076	Neoplasms	-	Neoplastic Process	group
TCMBANKDI000088	Neoplasms; Respiratory Tract Diseases	Neoplasm; Abnormality of the respiratory system	Neoplastic Process	group
TCMBANKDI000092	Respiratory Tract Diseases	Abnormality of the respiratory system	Disease or Syndrome	disease
TCMBANKDI000166	-	-	Neoplastic Process	disease
TCMBANKDI000633	Skin and Connective Tissue Diseases; Musculoskeletal Diseases	-	Disease or Syndrome	group
TCMBANKDI000771	Skin and Connective Tissue Diseases	Abnormality of the integument; Abnormality of the immune system	Sign or Symptom	phenotype
TCMBANKDI001139	Pathological Conditions, Signs and Symptoms; Musculoskeletal Diseases; Stomatognathic Diseases	-	Disease or Syndrome	disease
TCMBANKDI001706	Musculoskeletal Diseases	Abnormality of limbs; Abnormality of the skeletal system	Disease or Syndrome	disease
TCMBANKDI002441	Neoplasms	Neoplasm; Abnormality of the skeletal system	Neoplastic Process	disease
TCMBANKDI002974	Neoplasms	-	Neoplastic Process	disease
TCMBANKDI003353	Pathological Conditions, Signs and Symptoms; Neoplasms	-	Neoplastic Process	phenotype
TCMBANKDI003932	Neoplasms; Musculoskeletal Diseases	Abnormality of the skeletal system	Disease or Syndrome	disease
TCMBANKDI004646	Nervous System Diseases	Abnormality of the nervous system	Disease or Syndrome	disease
TCMBANKDI007135	-	-	Disease or Syndrome	disease
TCMBANKDI007856	-	Abnormality of the skeletal system	Anatomical Abnormality	disease
TCMBANKDI009135	Neoplasms	Neoplasm; Abnormality of the skeletal system	Neoplastic Process	disease
TCMBANKDI009951	Nutritional and Metabolic Diseases; Musculoskeletal Diseases	Abnormality of the skeletal system	Disease or Syndrome	disease
TCMBANKDI010048	Infections; Respiratory Tract Diseases	Abnormality of the immune system; Abnormality of the respiratory system	Disease or Syndrome	disease
TCMBANKDI010160	Respiratory Tract Diseases	Abnormality of the respiratory system	Disease or Syndrome	group
TCMBANKDI010395	Neoplasms	-	Neoplastic Process	disease
TCMBANKDI010896	Nervous System Diseases	Abnormality of the nervous system	Disease or Syndrome	group
TCMBANKDI011743	Neoplasms; Skin and Connective Tissue Diseases	Neoplasm; Abnormality of the breast	Neoplastic Process	group
TCMBANKDI014161	Stomatognathic Diseases	Abnormality of the immune system; Abnormality of head or neck	Disease or Syndrome	group
TCMBANKDI014531	Pathological Conditions, Signs and Symptoms; Neoplasms; Musculoskeletal Diseases	-	Neoplastic Process	disease
TCMBANKDI015485	Mental Disorders	Abnormality of the nervous system	Mental or Behavioral Dysfunction	disease
TCMBANKDI017024	Neoplasms; Respiratory Tract Diseases	-	Neoplastic Process	disease
TCMBANKDI017474	-	-	Disease or Syndrome	disease
TCMBANKDI017642	Neoplasms	Abnormality of the integument; Neoplasm	Neoplastic Process	disease
TCMBANKDI019825	Neoplasms	-	Neoplastic Process	disease
TCMBANKDI020103	Neoplasms	-	Neoplastic Process	disease
TCMBANKDI021089	Cardiovascular Diseases	-	Disease or Syndrome	disease
TCMBANKDI022565	-	-	Finding	phenotype
TCMBANKDI024875	Nutritional and Metabolic Diseases; Musculoskeletal Diseases	-	Disease or Syndrome	disease
TCMBANKDI025420	Digestive System Diseases; Neoplasms	Abnormality of the digestive system; Neoplasm	Neoplastic Process	disease
TCMBANKDI026528	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Musculoskeletal Diseases	-	Disease or Syndrome	disease
TCMBANKDI026667	-	-	Disease or Syndrome	disease
TCMBANKDI026963	Pathological Conditions, Signs and Symptoms	-	Acquired Abnormality	disease
TCMBANKDI028305	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases	Abnormality of limbs; Abnormality of the skeletal system	Congenital Abnormality	disease
TCMBANKDI028904	Pathological Conditions, Signs and Symptoms; Musculoskeletal Diseases; Stomatognathic Diseases	-	Disease or Syndrome	disease
TCMBANKDI029153	Stomatognathic Diseases	-	Disease or Syndrome	group
TCMBANKDI030540	Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases	Abnormality of the genitourinary system; Neoplasm	Neoplastic Process	disease
TCMBANKDI030607	Musculoskeletal Diseases	-	Disease or Syndrome	disease
TCMBANKDI031192	Neoplasms; Male Urogenital Diseases	-	Neoplastic Process	disease
TCMBANKDI032436	Musculoskeletal Diseases	-	Disease or Syndrome	disease