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疾病ID:TCMBANKDI002441

疾病名:Giant Cell Tumor of Bone

MeSH_Name:Neoplasms

HPO_Name:Neoplasm; Abnormality of the skeletal system

UMLS_Name:Neoplastic Process

DO_Name:disease of anatomical entity; disease of cellular proliferation

疾病类型:disease

DisGeNET_Link:C0206638

MeSH_Link:C04

HPO_Link:HP:0002664; HP:0000924

UMLS_Link:T191

DO_Link:DOID:7; DOID:14566

HERB_ID:HBDIS004382

   疾病对应的植物
ID 拉丁名 药名 药用植物名 功能与主治 来源 药用部位 使用民族
   疾病对应的化合物
化合物ID 化合物名 别名 分子式 分子质量 Smiles
   疾病对应的靶点
靶点ID 基因名 基因别名 描述
TCMBANKGE001811 PTHLH BDE2; HHM; PLP; PTHR; PTHRP parathyroid hormone like hormone
TCMBANKGE000429 CD36 BDPLT10; CHDS7; FAT; GP3B; GP4; GPIV; PASIV; SCARB3 CD36 molecule
TCMBANKGE002301 SFRP4 FRP-4; FRPHE; FRZB-2; PYL; sFRP-4 secreted frizzled related protein 4
TCMBANKGE000973 EGF HOMG4; URG epidermal growth factor
TCMBANKGE001180 SMAD3 HSPC193; HsT17436; JV15-2; LDS1C; LDS3; MADH3 SMAD family member 3
TCMBANKGE000117 RUNX3 AML2; CBFA3; PEBP2aC RUNX family transcription factor 3
TCMBANKGE006975 THBS1 THBS; THBS-1; TSP; TSP-1; TSP1 thrombospondin 1
TCMBANKGE001104 TGFB2 G-TSF; LDS4; TGF-beta2 transforming growth factor beta 2
TCMBANKGE001010 TNFRSF10A APO2; CD261; DR4; TRAILR-1; TRAILR1 TNF receptor superfamily member 10a
TCMBANKGE000173 BRAF B-RAF1; B-raf; BRAF1; NS7; RAFB1 B-Raf proto-oncogene, serine/threonine kinase
TCMBANKGE002081 COA1 C7orf44; MITRAC15 cytochrome c oxidase assembly factor 1 homolog
TCMBANKGE000162 MMP13 CLG3; MANDP1; MDST; MMP-13 matrix metallopeptidase 13
TCMBANKGE001015 RAC1 MIG5; MRD48; Rac-1; TC-25; p21-Rac1 Rac family small GTPase 1
TCMBANKGE001103 MDM2 ACTFS; HDMX; LSKB; hdm2 MDM2 proto-oncogene
TCMBANKGE008312 CKAP4 CLIMP-63; CLIMP63; ERGIC-63; p63 cytoskeleton associated protein 4
TCMBANKGE007646 DPT TRAMP dermatopontin
TCMBANKGE000578 ANGPTL4 ARP4; FIAF; HARP; HFARP; NL2; PGAR; TGQTL; UNQ171; pp1158 angiopoietin like 4
TCMBANKGE009229 MSC ABF-1; ABF1; MYOR; bHLHa22 musculin
TCMBANKGE000368 PLAUR CD87; U-PAR; UPAR; URKR plasminogen activator, urokinase receptor
TCMBANKGE000274 CCL2 GDCF-2; HC11; HSMCR30; MCAF; MCP-1; MCP1; SCYA2; SMC-CF C-C motif chemokine ligand 2
TCMBANKGE010699 NFIB CTF; HMGIC/NFIB; MACID; NF-I/B; NF1-B; NFI-B; NFI-RED; NFIB2; NFIB3 nuclear factor I B
TCMBANKGE000009 GJA1 AVSD3; CMDR; CX43; EKVP; EKVP3; GJAL; HLHS1; HSS; ODDD; PPKCA gap junction protein alpha 1
TCMBANKGE007506 CTSZ CTSX cathepsin Z
TCMBANKGE000047 AKT1 AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA AKT serine/threonine kinase 1
TCMBANKGE000680 CTSK CTS02; CTSO; CTSO1; CTSO2; PKND; PYCD cathepsin K
TCMBANKGE003444 EWSR1 EWS; EWS-FLI1; bK984G1.4 EWS RNA binding protein 1
TCMBANKGE000925 PCNA ATLD2 proliferating cell nuclear antigen
TCMBANKGE005933 LUM LDC; SLRR2D lumican
TCMBANKGE000319 GPX1 GPXD; GSHPX1 glutathione peroxidase 1
TCMBANKGE000201 ESR1 ER; ESR; ESRA; ESTRR; Era; NR3A1 estrogen receptor 1
TCMBANKGE000168 NR3C1 GCCR; GCR; GCRST; GR; GRL nuclear receptor subfamily 3 group C member 1
TCMBANKGE000892 SP7 OI11; OI12; OSX; osterix Sp7 transcription factor
TCMBANKGE006562 PDCD5 TFAR19 programmed cell death 5
TCMBANKGE000331 CALCA CALC1; CGRP; CGRP-I; CGRP-alpha; CGRP1; CT; KC; PCT calcitonin related polypeptide alpha
TCMBANKGE003071 P2RY2 HP2U; P2RU1; P2U; P2U1; P2UR; P2Y2; P2Y2R purinergic receptor P2Y2
TCMBANKGE001037 MMP2 CLG4; CLG4A; MMP-2; MMP-II; MONA; TBE-1 matrix metallopeptidase 2
TCMBANKGE000627 BGLAP BGP; OC; OCN bone gamma-carboxyglutamate protein
TCMBANKGE000204 CXCL8 GCP-1; GCP1; IL8; LECT; LUCT; LYNAP; MDNCF; MONAP; NAF; NAP-1; NAP1; SCYB8 C-X-C motif chemokine ligand 8
TCMBANKGE001063 CEBPB C/EBP-beta; IL6DBP; NF-IL6; TCF5 CCAAT enhancer binding protein beta
TCMBANKGE000142 CALCR CRT; CT-R; CTR; CTR1 calcitonin receptor
TCMBANKGE000401 WEE1 WEE1A; WEE1hu WEE1 G2 checkpoint kinase
TCMBANKGE000976 TNFSF11 CD254; ODF; OPGL; OPTB2; RANKL; TNLG6B; TRANCE; hRANKL2; sOdf TNF superfamily member 11
TCMBANKGE014347 FGF11 FGF-11; FHF-3; FHF3 fibroblast growth factor 11
TCMBANKGE000898 MYC MRTL; MYCC; bHLHe39; c-Myc MYC proto-oncogene, bHLH transcription factor
TCMBANKGE000202 RUNX2 AML3; CBF-alpha-1; CBFA1; CCD; CCD1; CLCD; OSF-2; OSF2; PEA2aA; PEBP2aA RUNX family transcription factor 2
TCMBANKGE004816 PDIA6 ERP5; P5; TXNDC7 protein disulfide isomerase family A member 6
TCMBANKGE001097 HIF1A HIF-1-alpha; HIF-1A; HIF-1alpha; HIF1; HIF1-ALPHA; MOP1; PASD8; bHLHe78 hypoxia inducible factor 1 subunit alpha
TCMBANKGE004101 RPE65 BCO3; LCA2; RP20; mRPE65; p63; rd12; sRPE65 retinoid isomerohydrolase RPE65
TCMBANKGE008107 S100A1 S100; S100-alpha; S100A S100 calcium binding protein A1
TCMBANKGE005625 DIO3 5DIII; D3; DIOIII; TXDI3 iodothyronine deiodinase 3
TCMBANKGE004266 AR AIS; AR8; DHTR; HUMARA; HYSP1; KD; NR3C4; SBMA; SMAX1; TFM androgen receptor
TCMBANKGE001007 NR1I2 BXR; ONR1; PAR; PAR1; PAR2; PARq; PRR; PXR; SAR; SXR nuclear receptor subfamily 1 group I member 2
TCMBANKGE000681 TNFRSF11B OCIF; OPG; PDB5; TR1 TNF receptor superfamily member 11b
TCMBANKGE014561 ANXA2 ANX2; ANX2L4; CAL1H; HEL-S-270; LIP2; LPC2; LPC2D; P36; PAP-IV annexin A2
TCMBANKGE000569 CD34 - CD34 molecule
TCMBANKGE005666 DCN CSCD; DSPG2; PG40; PGII; PGS2; SLRR1B decorin
TCMBANKGE001739 THBS2 TSP2 thrombospondin 2
TCMBANKGE005329 HOXA1 BSAS; HOX1; HOX1F homeobox A1
TCMBANKGE000935 S100B NEF; S100; S100-B; S100beta S100 calcium binding protein B
TCMBANKGE007816 UVRAG DHTX; VPS38; p63 UV radiation resistance associated
TCMBANKGE011987 TP63 AIS; B(p51A); B(p51B); EEC3; KET; LMS; NBP; OFC8; RHS; SHFM4; TP53CP; TP53L; TP73L; p40; p51; p53CP; p63; p73H; p73L tumor protein p63
TCMBANKGE003250 CD276 4Ig-B7-H3; B7-H3; B7H3; B7RP-2 CD276 molecule
TCMBANKGE001159 STAT1 CANDF7; IMD31A; IMD31B; IMD31C; ISGF-3; STAT91 signal transducer and activator of transcription 1
TCMBANKGE000328 PTPN11 BPTP3; CFC; JMML; METCDS; NS1; PTP-1D; PTP2C; SH-PTP2; SH-PTP3; SHP2 protein tyrosine phosphatase non-receptor type 11
TCMBANKGE001144 CD14 - CD14 molecule
TCMBANKGE000072 CXCL12 IRH; PBSF; SCYB12; SDF1; TLSF; TPAR1 C-X-C motif chemokine ligand 12
TCMBANKGE000679 BTF3P11 BTF3L1; HUMBTFB; OCIF; OPG; TNFRSF11B basic transcription factor 3 pseudogene 11
TCMBANKGE001021 MUC1 ADMCKD; ADMCKD1; CA 15-3; CD227; EMA; H23AG; KL-6; MAM6; MCD; MCKD; MCKD1; MUC-1; MUC-1/SEC; MUC-1/X; MUC1/ZD; PEM; PEMT; PUM mucin 1, cell surface associated
TCMBANKGE009742 HLA-DRB1 DRB1; HLA-DR1B; HLA-DRB; SS1 major histocompatibility complex, class II, DR beta 1
TCMBANKGE000988 HGF DFNB39; F-TCF; HGFB; HPTA; SF hepatocyte growth factor
TCMBANKGE000885 SPP1 BNSP; BSPI; ETA-1; OPN secreted phosphoprotein 1
TCMBANKGE001125 IGF1 IGF; IGF-I; IGFI; MGF insulin like growth factor 1
TCMBANKGE001045 CCND1 BCL1; D11S287E; PRAD1; U21B31 cyclin D1
TCMBANKGE000332 CCL20 CKb4; Exodus; LARC; MIP-3-alpha; MIP-3a; MIP3A; SCYA20; ST38 C-C motif chemokine ligand 20
TCMBANKGE000339 TNFRSF11A CD265; FEO; LOH18CR1; ODFR; OFE; OPTB7; OSTS; PDB2; RANK; TRANCER TNF receptor superfamily member 11a
TCMBANKGE013473 F2R CF2R; HTR; PAR-1; PAR1; TR coagulation factor II thrombin receptor
TCMBANKGE012224 VDR NR1I1; PPP1R163 vitamin D receptor
TCMBANKGE014757 IDH2 D2HGA2; ICD-M; IDH; IDHM; IDP; IDPM; mNADP-IDH isocitrate dehydrogenase (NADP(+)) 2
TCMBANKGE014602 ITGAV CD51; MSK8; VNRA; VTNR integrin subunit alpha V
TCMBANKGE010103 OPTN ALS12; FIP2; GLC1E; HIP7; HYPL; NRP; TFIIIA-INTP optineurin
TCMBANKGE000771 TWIST1 ACS3; BPES2; BPES3; CRS; CRS1; CSO; SCS; SWCOS; TWIST; bHLHa38 twist family bHLH transcription factor 1
TCMBANKGE001493 CTSA GLB2; GSL; NGBE; PPCA; PPGB cathepsin A
TCMBANKGE003326 MARK2 EMK-1; EMK1; PAR-1; Par-1b; Par1b microtubule affinity regulating kinase 2
TCMBANKGE012142 GDE1 363E6.2; MIR16 glycerophosphodiester phosphodiesterase 1
TCMBANKGE015058 DLK1 DLK; DLK-1; Delta1; FA1; PREF1; Pref-1; ZOG; pG2 delta like non-canonical Notch ligand 1

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