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HPD

靶点ID:TCMBANKGE005788

靶点别名:4-HPPD; 4HPPD; GLOD3; HPPDASE; PPD

靶点描述:4-hydroxyphenylpyruvate dioxygenase

染色体:12

染色体位置:12q24.31

靶点类型:protein-coding

HERB_ID:-

HGNC_Link:5147

OMIM_Link:609695

Ensembl_Link:ENSG00000158104

靶点对应的植物

ID	拉丁名	药名	药用植物名	功能与主治	来源	药用部位	使用民族

靶点对应的化合物

化合物ID	化合物名	别名	分子式	分子质量	Smiles

TCMBANKIN056613	7-O-Methyl leucopelargonidin-3-mono-glucofuranoside	usnicacid; usnic acid; (?)-usnicacid	C22H26O11	466.435	c1(OC([H])([H])[H])c([H])c(O[C@@]([H])(c2c([H])c([H])c(O[H])c([H])c2[H])[C@]([H])(O[C@]3([H])[C@@]([H])(O[H])[C@]([H])(O[H])[C@]([H])([C@@]([H])(C([H])([H])O[H])O[H])O3)[C@@]4([H])O[H])c4c(O[H])c1[H]
TCMBANKIN057905	ferrum	iron	Fe	55.84 g/mol	[Fe]
TCMBANKIN058172	OMD	2-(2,5-dihydroxyphenyl)acetic acid; 53560_FLUKA; NSC88940; CHEBI:44747; ST5406743; 2-(2,5-dihydroxyphenyl)ethanoic acid; Homogentisinic acid; Benzeneacetic acid, 3,4-dihydroxy-, homopolymer; 2-(3,6-DIHYDROXYPHENYL)ACETIC ACID; AIDS002960; AIDS-220865; 2,5-DHPOP; EINECS 207-192-7; (2,5-Dihydroxyphenyl)acetic acid; H0751_SIGMA; BRN 2692860; InChI=1/C8H8O4/c9-6-1-2-7(10)5(3-6)4-8(11)12/h1-3,9-10H,4H2,(H,11,12; 2,5-Dihydroxybenzeneacetic acid; 2,5-Dihydroxyphenylacetic acid polymer; NSC 88940; AIDS-002960; Acetic acid, (2,5-dihydroxyphenyl)-; 2,5-Dihydroxyphenylacetic acid; Alcapton; Benzeneacetic acid, 2,5-dihydroxy-; 451-13-8; 71694-00-3; C00544; 2,5-Dihydroxy-.alpha.-toluic acid; Homogentisate acid; Homogentisic acid; AIDS220865; 2,5-Dihydroxy-alpha-toluic acid; 4-10-00-01506 (Beilstein Handbook Reference); himigentisic acid	C8H8O4	168.15 g/mol	C1=CC(=C(C=C1O)CC(=O)O)O
TCMBANKIN058298	(7R)-mandelic acid 7-O-β-D-glucopyranoside		C8H8O3		C1=CC=C(C=C1)C(C(=O)O)O
TCMBANKIN059683	USNIC ACID		C18H16O7	344.32	CC1=C(C(=C2C(=C1O)C3(C(=CC(=O)C(C3=O)C(=O)C)O2)C)C(=O)C)O

靶点对应的疾病

疾病ID	疾病名	MeSH名	HPO名	UMLS名	疾病类型

TCMBANKDI003353	Pathological Conditions, Signs and Symptoms; Neoplasms	-	Neoplastic Process	phenotype
TCMBANKDI003411	-	-	Disease or Syndrome	disease
TCMBANKDI005318	Digestive System Diseases; Chemically-Induced Disorders	-	Disease or Syndrome	disease
TCMBANKDI005587	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases	Abnormality of limbs; Abnormality of the skeletal system	Congenital Abnormality	disease
TCMBANKDI009278	Mental Disorders	-	Mental or Behavioral Dysfunction	group
TCMBANKDI009951	Nutritional and Metabolic Diseases; Musculoskeletal Diseases	Abnormality of the skeletal system	Disease or Syndrome	disease
TCMBANKDI011217	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Nervous System Diseases	-	Disease or Syndrome	disease
TCMBANKDI011359	Stomatognathic Diseases	-	Disease or Syndrome	phenotype
TCMBANKDI014161	Stomatognathic Diseases	Abnormality of the immune system; Abnormality of head or neck	Disease or Syndrome	group
TCMBANKDI014359	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases	-	Congenital Abnormality	group
TCMBANKDI015336	-	-	Disease or Syndrome	phenotype
TCMBANKDI015485	Mental Disorders	Abnormality of the nervous system	Mental or Behavioral Dysfunction	disease
TCMBANKDI015870	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases	-	Congenital Abnormality	disease
TCMBANKDI016330	Mental Disorders	-	Mental or Behavioral Dysfunction	disease
TCMBANKDI017024	Neoplasms; Respiratory Tract Diseases	-	Neoplastic Process	disease
TCMBANKDI017856	Infections	-	Disease or Syndrome	disease
TCMBANKDI019143	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms; Musculoskeletal Diseases; Nervous System Diseases	-	Disease or Syndrome	disease
TCMBANKDI023697	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Nervous System Diseases	-	Disease or Syndrome	disease
TCMBANKDI023751	Pathological Conditions, Signs and Symptoms; Nervous System Diseases	Abnormality of the musculature	Finding	phenotype
TCMBANKDI024535	Neoplasms; Respiratory Tract Diseases	Neoplasm; Abnormality of the respiratory system	Neoplastic Process	disease
TCMBANKDI025420	Digestive System Diseases; Neoplasms	Abnormality of the digestive system; Neoplasm	Neoplastic Process	disease
TCMBANKDI030837	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases	Abnormality of limbs; Abnormality of the skeletal system	Congenital Abnormality	disease