Compound Summary

  Compound Information

TCMBANKIN000096

药名:	oridonin
别名:	Rub A
分子式:	C20H28O6
Smiles:	CC1(CCC(C23C1C(C(C45C2CCC(C4O)C(=C)C5=O)(OC3)O)O)O)C
成分:	HBIN038254
TCMID_id:	16173
PubChem_id:	138107787

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   化合物对应的植物

植物ID	拉丁名	药用植物名	药名	来源	功能与主治	使用民族

TCMBANKHE002319	Isodon japonica var. glaucocalyx	蓝萼香茶菜
TCMBANKHE002342	Isodon lasiocarpus	迷案毛果香茶菜
TCMBANKHE002613	Isodon rubescens var. lushanensis	庐山香茶菜
TCMBANKHE003637	Parmelia tinctorum				To boost essence, brighten eyes, cool blood and resolve toxin./Dim vision, flooding and spotting, bleeding due to external injury, sore toxin and intractable lichen.
TCMBANKHE004235	Erica umbellata	伞形欧石南
TCMBANKHE004711	Rabdosia rubescens	冬淩草			To clear heat and resolve toxin, quicken blood and relieve pain, anticancer./Swelling pain in throat, common cold with headache, trachitis, chronic hepatitis, pain in joints due to rheumatalgia, snake or insect bites, carcinoma of mammary glands, carcinoma of esophagus.
TCMBANKHE005547	Rabdosia macrophylla	大叶香茶菜
TCMBANKHE005695	Isodon amethystoides;Plectranthus nummularius;Isodon shikokiana var. occidentalis;Isodon latifolia var. reniformis	香茶菜			Aerial parts: To clear heat and disinhibit damp, quicken blood and dissipate stasis, resolve toxin and disperse swelling; Root: To clear heat and resolve toxin, dispel stasis and relieve pain./Aerial parts: Damp-heat jaundice, strangury, edema, swelling pain in throat, impediment pain in joints, menstrual block, mammary welling abscess, hemorrhoids, effusion of back, knocks and falls, poisonous snake bite; Root: Poisonous snake bites, swelling toxin of sore and boil, aching sinews and bones, knocks and falls, burns and scalds.
TCMBANKHE006277	Rabdosia nervosa	显脉香茶菜			To disinhibit damp and harmonize stomach, resolve toxin and close sores./Acute hepatitis, indigestion, pemphigus, eczema, itchy skin, burns and scalds, poisonous snake bites.
TCMBANKHE008458	Isodon japonica [Syn. Rabdosia japonica ]	毛叶香茶菜			To clear heat and resolve toxin, quicken blood and disperse swelling./Hepatitis, gastritis, mastitis, amenorrhea, knocks and falls, pain in joints, snake or insect bites.
TCMBANKHE005995	Isodon trichocarpa	毛果香茶菜
TCMBANKHE006667	Isodon rugosus [Syn. Rabdosia rugosa]	皱叶香茶菜
TCMBANKHE008620	Erica arborea	欧石楠

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   植物对应的疾病

疾病ID	病名	疾病类型	MeSH	参考文献

TCMBANKDI000022	Prostatic Neoplasms	group	Neoplasms; Male Urogenital Diseases	20872277
TCMBANKDI000052	Osteoporosis	disease	Nutritional and Metabolic Diseases; Musculoskeletal Diseases	29091322
TCMBANKDI000053	leukemia	disease	Neoplasms	24872388
TCMBANKDI000055	Peritonitis	disease	Digestive System Diseases; Infections	29959312
TCMBANKDI000061	Esophageal Neoplasms	group	Digestive System Diseases; Neoplasms	28411855
TCMBANKDI000069	Bone neoplasms	group	Neoplasms; Musculoskeletal Diseases	29323103
TCMBANKDI000070	Osteosarcoma	disease	Neoplasms	29323103
TCMBANKDI000085	Inflammation	phenotype	Pathological Conditions, Signs and Symptoms	29959312
TCMBANKDI004976	Cardiotoxicity	disease	Pathological Conditions, Signs and Symptoms; Chemically-Induced Disorders; Cardiovascular Diseases; Wounds and Injuries	31202781
TCMBANKDI009722	Cardiac Hypertrophy	phenotype	Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases	31127082
TCMBANKDI014740	Ascites	phenotype	Pathological Conditions, Signs and Symptoms	20872277
TCMBANKDI015740	Colorectal Neoplasms	group	Digestive System Diseases; Neoplasms	28230866
TCMBANKDI023864	Arthritis, Gouty	disease	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Musculoskeletal Diseases	29959312
TCMBANKDI026887	ovarian neoplasm	disease	Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases	20872277
TCMBANKDI029884	Acute Lung Injury	disease	Respiratory Tract Diseases	31186013

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   化合物对应的靶点

靶点ID	基因名	基因别名	描述

TCMBANKGE000047	AKT1	AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA	AKT serine/threonine kinase 1
TCMBANKGE000053	NFKB1	CVID12; EBP-1; KBF1; NF-kB; NF-kB1; NF-kappa-B1; NF-kappaB; NF-kappabeta; NFKB-p105; NFKB-p50; NFkappaB	nuclear factor kappa B subunit 1
TCMBANKGE000294	CDKN1A	CAP20; CDKN1; CIP1; MDA-6; P21; SDI1; WAF1; p21CIP1	cyclin dependent kinase inhibitor 1A
TCMBANKGE000301	SLC2A1	CSE; DYT17; DYT18; DYT9; EIG12; GLUT; GLUT-1; GLUT1; GLUT1DS; HTLVR; PED; SDCHCN	solute carrier family 2 member 1
TCMBANKGE000330	HMOX1	HMOX1D; HO-1; HSP32; bK286B10	heme oxygenase 1
TCMBANKGE000969	TXN	TRDX; TRX; TRX1	thioredoxin
TCMBANKGE000970	FASN	FAS; OA-519; SDR27X1	fatty acid synthase
TCMBANKGE000971	MIR20A	C13orf25; MIR17HG; MIR20; MIRH1; MIRHG1; MIRN20; MIRN20A; hsa-mir-20; hsa-mir-20a; miR-20; miRNA20A; mir-20a	microRNA 20a
TCMBANKGE000972	MIR17	MIR17-5p; MIR91; MIRN17; MIRN91; hsa-mir-17; miR-17; miR17-3p; miRNA17; miRNA91	microRNA 17
TCMBANKGE000973	EGF	HOMG4; URG	epidermal growth factor
TCMBANKGE000974	SMAD5	DWFC; JV5-1; MADH5	SMAD family member 5
TCMBANKGE000975	IFRD1	PC4; TIS7	interferon related developmental regulator 1
TCMBANKGE000976	TNFSF11	CD254; ODF; OPGL; OPTB2; RANKL; TNLG6B; TRANCE; hRANKL2; sOdf	TNF superfamily member 11
TCMBANKGE000977	SMAD1	BSP-1; BSP1; JV4-1; JV41; MADH1; MADR1	SMAD family member 1
TCMBANKGE000978	GCLM	GLCLR	glutamate-cysteine ligase modifier subunit
TCMBANKGE000979	KDR	CD309; FLK1; VEGFR; VEGFR2	kinase insert domain receptor
TCMBANKGE000987	COL11A2	DFNA13; DFNB53; FBCG2; HKE5; OSMEDA; OSMEDB; PARP; STL3	collagen type XI alpha 2 chain
TCMBANKGE000990	EGFR	ERBB; ERBB1; HER1; NISBD2; PIG61; mENA	epidermal growth factor receptor
TCMBANKGE001013	BIRC5	API4; EPR-1	baculoviral IAP repeat containing 5
TCMBANKGE001052	NLRP3	AGTAVPRL; AII; AVP; C1orf7; CIAS1; CLR1.1; DFNA34; FCAS; FCAS1; FCU; KEFH; MWS; NALP3; PYPAF1	NLR family pyrin domain containing 3
TCMBANKGE001098	NFKBIA	EDAID2; IKBA; MAD-3; NFKBI	NFKB inhibitor alpha
TCMBANKGE001126	NFE2L2	HEBP1; IMDDHH; NRF2; Nrf-2	nuclear factor, erythroid 2 like 2
TCMBANKGE001127	PRKAA1	AMPK; AMPKa1	protein kinase AMP-activated catalytic subunit alpha 1
TCMBANKGE001131	CASP9	APAF-3; APAF3; ICE-LAP6; MCH6; PPP1R56	caspase 9
TCMBANKGE001132	BAX	BCL2L4	BCL2 associated X, apoptosis regulator
TCMBANKGE001135	SREBF1	SREBP1; bHLHd1	sterol regulatory element binding transcription factor 1
TCMBANKGE001156	CASP3	CPP32; CPP32B; SCA-1	caspase 3
TCMBANKGE001166	BCL2	Bcl-2; PPP1R50	BCL2 apoptosis regulator
TCMBANKGE001177	TP53	BCC7; BMFS5; LFS1; P53; TRP53	tumor protein p53
TCMBANKGE001184	RELA	CMCU; NFKB3; p65	RELA proto-oncogene, NF-kB subunit
TCMBANKGE001185	PPARG	CIMT1; GLM1; NR1C3; PPARG1; PPARG2; PPARG5; PPARgamma	peroxisome proliferator activated receptor gamma