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疾病ID:TCMBANKDI029081

疾病名:Alveolar Bone Loss

MeSH_Name:Musculoskeletal Diseases; Stomatognathic Diseases

HPO_Name:Abnormality of head or neck

UMLS_Name:Disease or Syndrome

DO_Name:-

疾病类型:disease

DisGeNET_Link:C0002382

MeSH_Link:C05; C07

HPO_Link:HP:0000152

UMLS_Link:T047

DO_Link:-

HERB_ID:-

   疾病对应的植物
ID 拉丁名 药名 药用植物名 功能与主治 来源 药用部位 使用民族
   疾病对应的化合物
化合物ID 化合物名 别名 分子式 分子质量 Smiles
TCMBANKIN036846 Icariin 5-hydroxy-2-(4-methoxyphenyl)-8-(3-methylbut-2-enyl)-7-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]oxy-3-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyl-tetrahydropyran-2-yl]oxy-chromen-4-one; MLS000759413; Spectrum4_001975; ZINC03960893; 5-hydroxy-2-(4-methoxyphenyl)-8-(3-methylbut-2-enyl)-7-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyl-oxan-2-yl]oxy-chromen-4-one; Spectrum2_001695; 5-hydroxy-2-(4-methoxyphenyl)-8-(3-methylbut-2-enyl)-7-[[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)-2-tetrahydropyranyl]oxy]-3-[[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyl-2-tetrahydropyranyl]oxy]-4-chromenone; 5-hydroxy-2-(4-methoxyphenyl)-8-(3-methylbut-2-enyl)-7-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-methylol-tetrahydropyran-2-yl]oxy-3-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyl-tetrahydropyran-2-yl]oxy-chromone; Spectrum3_001130; 5-hydroxy-2-(4-methoxyphenyl)-8-(3-methylbut-2-enyl)-7-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxychromen-4-one; 489-32-7; 2-(4'-methoxyl phenyl)-3-rhamnosido-5-hydroxyl-7-glucosido-8-(3'-methyl-2-butylenyl)-4-chromanone; SPBio_001650; SPECTRUM1505257; KBio3_002099; KBioGR_002475; SDCCGMLS-0066754.P001; SMR000466309; BB_NC-0999; 3-((6-Deoxymannopyranosyl)oxy)-7-(glucopyranosyloxy)-5-hydroxy-2-(4-methoxyphenyl)-8-(3-methyl-2-butenyl)-4H-1-benzopyran-4-one; Spectrum5_000933; icariin; BSPBio_002599; 4H-1-Benzopyran-4-one, 3-((6-deoxy-alpha-L-mannopyranosyl)oxy)-7-(beta-D-glucopyranosyloxy)-5-hydroxy-2-(4-methoxyphenyl)-8-(3-methyl-2-butenyl)-; ICA C33H40O15 677 O1[C@@]([H])(Oc2c(C([H])([H])\C([H])=C(/C([H])([H])[H])\C([H])([H])[H])c(OC(c3c([H])c([H])c(OC([H])([H])[H])c([H])c3[H])=C(O[C@@]4([H])[C@]([H])(O[H])[C@]([H])(O[H])[C@@]([H])(O[H])[C@]([H])(C([H])([H ])[H])O4)C5=O)c5c(O[H])c2[H])[C@]([H])(O[H])[C@@]([H])(O[H])[C@]([H])(O[H])[C@@]1([H])C([H])([H])O[H]
   疾病对应的靶点
靶点ID 基因名 基因别名 描述
TCMBANKGE001811 PTHLH BDE2; HHM; PLP; PTHR; PTHRP parathyroid hormone like hormone
TCMBANKGE000799 AGER RAGE; SCARJ1 advanced glycosylation end-product specific receptor
TCMBANKGE000429 CD36 BDPLT10; CHDS7; FAT; GP3B; GP4; GPIV; PASIV; SCARB3 CD36 molecule
TCMBANKGE012711 SH3BP2 3BP-2; 3BP2; CRBM; CRPM; RES4-23 SH3 domain binding protein 2
TCMBANKGE004814 FBLIM1 CAL; FBLP-1; FBLP1 filamin binding LIM protein 1
TCMBANKGE000857 AHSA1 AHA1; C14orf3; hAha1; p38 activator of HSP90 ATPase activity 1
TCMBANKGE001876 DMP1 ARHP; ARHR; DMP-1 dentin matrix acidic phosphoprotein 1
TCMBANKGE008004 ASPN OS3; PLAP-1; PLAP1; SLRR1C asporin
TCMBANKGE000798 MYD88 MYD88D MYD88 innate immune signal transduction adaptor
TCMBANKGE014577 TIMELESS TIM; TIM1; hTIM timeless circadian regulator
TCMBANKGE003153 DMD BMD; CMD3B; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272; MRX85 dystrophin
TCMBANKGE000752 Il33 9230117N10Rik; Il-33; Il1f11; NF-HEV interleukin 33
TCMBANKGE000162 MMP13 CLG3; MANDP1; MDST; MMP-13 matrix metallopeptidase 13
TCMBANKGE013010 COX2 COII; MTCO2 cytochrome c oxidase subunit II
TCMBANKGE008151 SPARC BM-40; OI17; ON; ONT secreted protein acidic and cysteine rich
TCMBANKGE014985 PTH FIH1; PTH1 parathyroid hormone
TCMBANKGE000229 ACE2 ACEH angiotensin I converting enzyme 2
TCMBANKGE000274 CCL2 GDCF-2; HC11; HSMCR30; MCAF; MCP-1; MCP1; SCYA2; SMC-CF C-C motif chemokine ligand 2
TCMBANKGE006267 CYP27B1 CP2B; CYP1; CYP1alpha; CYP27B; P450c1; PDDR; VDD1; VDDR; VDDRI; VDR cytochrome P450 family 27 subfamily B member 1
TCMBANKGE005314 SOST CDD; DAND6; SOST1; VBCH sclerostin
TCMBANKGE009482 CD40LG CD154; CD40L; HIGM1; IGM; IMD3; T-BAM; TNFSF5; TRAP; gp39; hCD40L CD40 ligand
TCMBANKGE001203 MAPK1 ERK; ERK-2; ERK2; ERT1; MAPK2; P42MAPK; PRKM1; PRKM2; p38; p40; p41; p41mapk; p42-MAPK mitogen-activated protein kinase 1
TCMBANKGE000201 ESR1 ER; ESR; ESRA; ESTRR; Era; NR3A1 estrogen receptor 1
TCMBANKGE000882 SERPINE1 PAI; PAI-1; PAI1; PLANH1 serpin family E member 1
TCMBANKGE013483 TNFSF13 APRIL; CD256; TALL-2; TALL2; TNLG7B; TRDL-1; UNQ383/PRO715; ZTNF2 TNF superfamily member 13
TCMBANKGE007872 TNFSF13B BAFF; BLYS; CD257; DTL; TALL-1; TALL1; THANK; TNFSF20; TNLG7A; ZTNF4 TNF superfamily member 13b
TCMBANKGE000329 STAT6 D12S1644; IL-4-STAT; STAT6B; STAT6C signal transducer and activator of transcription 6
TCMBANKGE003169 EDIL3 DEL1 EGF like repeats and discoidin domains 3
TCMBANKGE009373 MMP8 CLG1; HNC; MMP-8; PMNL-CL matrix metallopeptidase 8
TCMBANKGE000068 VEGFC Flt4-L; LMPH1D; LMPHM4; VRP vascular endothelial growth factor C
TCMBANKGE001034 TLR2 CD282; TIL4 toll like receptor 2
TCMBANKGE004741 TPM3 CAPM1; CFTD; HEL-189; HEL-S-82p; NEM1; OK/SW-cl.5; TM-5; TM3; TM30; TM30nm; TM5; TPM3nu; TPMsk3; TRK; hscp30 tropomyosin 3
TCMBANKGE000331 CALCA CALC1; CGRP; CGRP-I; CGRP-alpha; CGRP1; CT; KC; PCT calcitonin related polypeptide alpha
TCMBANKGE001069 MPO - myeloperoxidase
TCMBANKGE000901 ANGPT1 AGP1; AGPT; ANG1 angiopoietin 1
TCMBANKGE013349 DCSTAMP FIND; TM7SF4; hDC-STAMP dendrocyte expressed seven transmembrane protein
TCMBANKGE000976 TNFSF11 CD254; ODF; OPGL; OPTB2; RANKL; TNLG6B; TRANCE; hRANKL2; sOdf TNF superfamily member 11
TCMBANKGE007023 GOPC CAL; FIG; GOPC1; PIST; dJ94G16.2 golgi associated PDZ and coiled-coil motif containing
TCMBANKGE000687 POLDIP2 PDIP38; POLD4; p38 DNA polymerase delta interacting protein 2
TCMBANKGE001097 HIF1A HIF-1-alpha; HIF-1A; HIF-1alpha; HIF1; HIF1-ALPHA; MOP1; PASD8; bHLHe78 hypoxia inducible factor 1 subunit alpha
TCMBANKGE000346 RPS6KA3 CLS; HU-3; ISPK-1; MAPKAPK1B; MRX19; RSK; RSK2; S6K-alpha3; p90-RSK2; pp90RSK2 ribosomal protein S6 kinase A3
TCMBANKGE000791 DUSP1 CL100; HVH1; MKP-1; MKP1; PTPN10 dual specificity phosphatase 1
TCMBANKGE001202 MAPK14 CSBP; CSBP1; CSBP2; CSPB1; EXIP; Mxi2; PRKM14; PRKM15; RK; SAPK2A; p38; p38ALPHA mitogen-activated protein kinase 14
TCMBANKGE000001 CXCR2 CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB C-X-C motif chemokine receptor 2
TCMBANKGE001182 SIRT1 SIR2; SIR2L1; SIR2alpha sirtuin 1
TCMBANKGE001073 PTGS2 COX-2; COX2; GRIPGHS; PGG/HS; PGHS-2; PHS-2; hCox-2 prostaglandin-endoperoxide synthase 2
TCMBANKGE014252 IL15 IL-15 interleukin 15
TCMBANKGE000681 TNFRSF11B OCIF; OPG; PDB5; TR1 TNF receptor superfamily member 11b
TCMBANKGE006400 PLG - plasminogen
TCMBANKGE012425 TRAP - triiodothyronine receptor auxiliary protein
TCMBANKGE000327 SYK p72-Syk spleen associated tyrosine kinase
TCMBANKGE003030 ZFP36 G0S24; GOS24; NUP475; RNF162A; TIS11; TTP; zfp-36 ZFP36 ring finger protein
TCMBANKGE008490 RNF19A RNF19 ring finger protein 19A, RBR E3 ubiquitin protein ligase
TCMBANKGE000109 ACTB BRWS1; PS1TP5BP1 actin beta
TCMBANKGE001109 ALPP ALP; ALPI; IAP; PALP; PLAP; PLAP-1 alkaline phosphatase, placental
TCMBANKGE001011 TNFSF10 APO2L; Apo-2L; CD253; TL2; TNLG6A; TRAIL TNF superfamily member 10
TCMBANKGE012246 TLR9 CD289 toll like receptor 9
TCMBANKGE009400 GNAS AHO; C20orf45; GNAS1; GPSA; GSA; GSP; NESP; PITA3; POH; SCG6; SgVI GNAS complex locus
TCMBANKGE000856 CRK CRKII; p38 CRK proto-oncogene, adaptor protein
TCMBANKGE009361 GPT AAT1; ALT1; GPT1 glutamic--pyruvic transaminase
TCMBANKGE000679 BTF3P11 BTF3L1; HUMBTFB; OCIF; OPG; TNFRSF11B basic transcription factor 3 pseudogene 11
TCMBANKGE000689 GRAP2 GADS; GRAP-2; GRB2L; GRBLG; GRID; GRPL; GrbX; Grf40; Mona; P38 GRB2 related adaptor protein 2
TCMBANKGE006724 REN HNFJ2 renin
TCMBANKGE007252 IL22 IL-21; IL-22; IL-D110; IL-TIF; ILTIF; TIFIL-23; TIFa; zcyto18 interleukin 22
TCMBANKGE000988 HGF DFNB39; F-TCF; HGFB; HPTA; SF hepatocyte growth factor
TCMBANKGE000240 IL17A CTLA-8; CTLA8; IL-17; IL-17A; IL17 interleukin 17A
TCMBANKGE012402 NTRK1 MTC; TRK; TRK1; TRKA; Trk-A; p140-TrkA neurotrophic receptor tyrosine kinase 1
TCMBANKGE001096 TLR4 ARMD10; CD284; TLR-4; TOLL toll like receptor 4
TCMBANKGE006776 CDK9 C-2k; CDC2L4; CTK1; PITALRE; TAK cyclin dependent kinase 9
TCMBANKGE001732 ITGAL CD11A; LFA-1; LFA1A integrin subunit alpha L
TCMBANKGE001102 MIR21 MIRN21; hsa-mir-21; miR-21; miRNA21 microRNA 21
TCMBANKGE000749 ALOX5 5-LO; 5-LOX; 5LPG; LOG5 arachidonate 5-lipoxygenase
TCMBANKGE003208 DKK1 DKK-1; SK dickkopf WNT signaling pathway inhibitor 1
TCMBANKGE001108 BMP2 BDA2; BMP2A; SSFSC bone morphogenetic protein 2
TCMBANKGE003466 ARHGEF5 GEF5; P60; TIM; TIM1 Rho guanine nucleotide exchange factor 5
TCMBANKGE000725 FOSL1 FRA; FRA1; fra-1 FOS like 1, AP-1 transcription factor subunit
TCMBANKGE000339 TNFRSF11A CD265; FEO; LOH18CR1; ODFR; OFE; OPTB7; OSTS; PDB2; RANK; TRANCER TNF receptor superfamily member 11a
TCMBANKGE014324 HAVCR1 CD365; HAVCR; HAVCR-1; KIM-1; KIM1; TIM; TIM-1; TIM1; TIMD-1; TIMD1 hepatitis A virus cellular receptor 1
TCMBANKGE000688 AIMP2 HLD17; JTV-1; JTV1; P38 aminoacyl tRNA synthetase complex interacting multifunctional protein 2
TCMBANKGE012224 VDR NR1I1; PPP1R163 vitamin D receptor
TCMBANKGE001080 AHR RP85; bHLHe76 aryl hydrocarbon receptor
TCMBANKGE000326 SELP CD62; CD62P; GMP140; GRMP; LECAM3; PADGEM; PSEL selectin P
TCMBANKGE000783 PCSK9 FH3; FHCL3; HCHOLA3; LDLCQ1; NARC-1; NARC1; PC9 proprotein convertase subtilisin/kexin type 9
TCMBANKGE000624 ALPL AP-TNAP; APTNAP; HOPS; TNALP; TNAP; TNSALP alkaline phosphatase, biomineralization associated
TCMBANKGE000548 MFGE8 BA46; EDIL1; HMFG; HsT19888; MFG-E8; MFGM; OAcGD3S; SED1; SPAG10; hP47 milk fat globule EGF and factor V/VIII domain containing
TCMBANKGE006750 IL21 CVID11; IL-21; Za11 interleukin 21
TCMBANKGE011182 ITGB2 CD18; LAD; LCAMB; LFA-1; MAC-1; MF17; MFI7 integrin subunit beta 2
TCMBANKGE003550 PROS1 PROS; PS21; PS22; PS23; PS24; PS25; PSA; THPH5; THPH6 protein S
TCMBANKGE013151 TM7SF2 ANG1; C14SR; DHCR14A; NET47 transmembrane 7 superfamily member 2
TCMBANKGE003305 HBEGF DTR; DTS; DTSF; HEGFL heparin binding EGF like growth factor

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