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Plant Summary

Plant Information

TCMBank_ID:	TCMBANKHE004674
YEM_ID:	YEM-476
ID:	TCMBANKHE004674/YEM-476
植物拉丁名:	Cocculus laurifolius\|Cocculus laurifolius DC.
功能与主治:	To normalize qi and loosen chest, dispel wind and relieve pain./Hypertension, headache, mounting qi, abdominal pain, rheumatic pain in legs.
药用植物名:	衡州乌药\|樟叶木防已
药名:	樟叶木防已
来源:	云南民族药物志：第三卷
药用部位:	root or whole herb
使用民族:	傣族
TCM_ID_id:	7486

植物对应的化合物

化合物ID	化合物名	别名	分子式	分子质量	Smiles

TCMBANKIN001958	cocculolidine		C15H19NO3	261.32	COC1CC=C2CCN3C2(C1)C4=C(CC3)COC4=O
TCMBANKIN012791	Trilobine	trilobine; 6138-73-4; C09669; Oxyacanthan, 6',7-epoxy-6,12'-dimethoxy-2'-methyl-, (1'alpha)-	C35H34N2O5	562.65	CN1CCC2=CC3=C4C=C2C1CC5=CC(=C(C=C5)OC)OC6=CC=C(CC7C8=C(O4)C(=C(C=C8CCN7)OC)O3)C=C6
TCMBANKIN013343	isococculidine	2,12-dimethoxy-2,4a,5,6,8,9-hexahydro-1H-indolo[7a,1-a]isoquinoline; isococculidine ; AC1MR6LL	C18H23NO2	285.4 g/mol	COC1CC23C(CCN2CCC4=C3C=C(C=C4)OC)C=C1
TCMBANKIN014163	cocculine		C17H21NO2	271.35	COC1CC=C2CCN3C2(C1)C4=C(CC3)C=CC(=C4)O
TCMBANKIN016137	isoconessimine		C23H38N2	342.6 g/mol	CC1C2CCC3C2(CCC4C3CC=C5C4(CCC(C5)NC)C)CN1C
TCMBANKIN022910	cocculidine		C18H23NO2	285.4 g/mol	COC1CC=C2CCN3C2(C1)C4=C(CC3)C=CC(=C4)OC
TCMBANKIN023716	Laurifoline	(+)-Laurifoline; AKOS032962360; 7224-61-5; CHEMBL235429; MolPort-039-052-582; laurifoline; ZINC2007968	C20H24NO4+	342.4 g/mol	C[N+]1(CCC2=CC(=C(C3=C2C1CC4=CC(=C(C=C43)OC)O)O)OC)C
TCMBANKIN028295	retrorsine	.beta.-Longilobine; BCJMNZRQJAVDLD-XRVQXMHSSA-N; RETRORSINE	C18H25NO6	351.4 g/mol	CC=C1CC(C(C(=O)OCC2=CCN3C2C(CC3)OC1=O)(CO)O)C
TCMBANKIN032077	Erythroculine	erythroculine; AC1NSV8C; methyl 2,11-dimethoxy-2,3,5,6,8,9-hexahydro-1H-indolo[7a,1-a]isoquinoline-12-carboxylate	C20H25NO4	343.42	COC1CC=C2CCN3C2(C1)C4=C(CC3)C=C(C(=C4)C(=O)OC)OC
TCMBANKIN036800	erythrodiol	AKOS032948355; (3S,4aR,6aR,6bS,8aS,12aS,14aR,14bR)-8a-(hydroxymethyl)-4,4,6a,6b,11,11,14b-heptamethyl-1,2,3,4a,5,6,7,8,9,10,12,12a,14,14a-tetradecahydropicen-3-ol; Olean-12-ene-3beta,28-diol; erythro-diol; (3beta)-Olean-12-ene-3,28-diol; erythrodiol ; (4aR,6aR,6bS,8aS,12aS,14aR,14bR)-8a-(hydroxymethyl)-4,4,6a,6b,11,11,14b-heptamethyl-1,2,3,4a,5,6,7,8,9,10,12,12a,14,14a-tetradecahydropicen-3-ol; A830234; 545-48-2; EINECS 208-890-4; Erythrodiol; (3S,4aR,6aR,6bS,8aS,12aS,14aR,14bR)-4,4,6a,6b,11,11,14b-heptamethyl-8a-methylol-1,2,3,4a,5,6,7,8,9,10,12,12a,14,14a-tetradecahydropicen-3-ol; 09258_FLUKA	C30H50O2	443	C1([H])([H])C([H])([H])[C@](C([H])([H])[H])([C@@]([H])(C([H])([H])C([H])=C([C@@]([H])(C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C2([H])[H])[C@@]2(C([H])([H])O[H])C([H])([H])C3([H])[H])[C@ @]34C([H])([H])[H])[C@@]4(C([H])([H])[H])C([H])([H])C5([H])[H])[C@@]5([H])C(C([H])([H])[H])(C([H])([H])[H])[C@]1([H])O[H]
TCMBANKIN037989	trilobolide		C27H38O10	522.6 g/mol	CCC(C)C(=O)OC1CC(C2CC(C(=C2C3C1(C(C(=O)O3)(C)O)O)C)OC(=O)C(=CC)C)(C)OC(=O)C
TCMBANKIN048336	6-methylcryptoacetalide		C19H24O3	300.4 g/mol	CC1CC2(C3=C(C4=C(C(=C3)C)C(CCC4)(C)C)C(=O)O2)OC1
TCMBANKIN061324	d-reticuline	(S)-(+)-reticuline; (1S)-1-[(3-hydroxy-4-methoxy-phenyl)methyl]-6-methoxy-2-methyl-3,4-dihydro-1H-isoquinolin-7-ol; CHEBI:16718; 485-19-8; (1S)-1-(3-hydroxy-4-methoxy-benzyl)-6-methoxy-2-methyl-3,4-dihydro-1H-isoquinolin-7-ol; (+)-Reticuline; (1S)-1-(3-hydroxy-4-methoxybenzyl)-6-methoxy-2-methyl-1,2,3,4-tetrahydroisoquinolin-7-ol; (1S)-1-[(3-hydroxy-4-methoxyphenyl)methyl]-6-methoxy-2-methyl-3,4-dihydro-1H-isoquinolin-7-ol; C02105;CHEBI:17428; AC1L99KR; (R)-(-)-reticuline; (1R)-1,2,3,4-Tetrahydro-1-[(3-hydroxy-4-methoxyphenyl)methyl]-6-methoxy-2-methyl-7-isoquinolinol; AK552295; (1R)-1-(3-hydroxy-4-methoxybenzyl)-6-methoxy-2-methyl-1,2,3,4-tetrahydroisoquinolin-7-ol; C05178; FT-0699770; MFCD28556897; ZINC901258; DTXSID80331501; L-Reticuline; CHEMBL401501; AKOS030242061; (1R)-1-[(3-hydroxy-4-methoxyphenyl)methyl]-6-methoxy-2-methyl-3,4-dihydro-1H-isoquinolin-7-ol; (R)-Reticuline; (-)-reticuline; SCHEMBL9587509; NCGC00247617-01; 3968-19-2; (R)-Reticuline (>80% ee); CTK1C2641; (S)-Reticuline;reticuline;reticulin	C19H23NO4	329.4 g/mol	CN1CCC2=CC(=C(C=C2C1CC3=CC(=C(C=C3)OC)O)O)OC
TCMBANKIN061326	(R)-N-Methylcoclaurine	7-Isoquinolinol, 1,2,3,4-tetrahydro-1-[(4-hydroxyphenyl)methyl]-6-methoxy-2-methyl-, (1R)-; 1betaH-Coclaurine, 2-methyl-; 5096-70-8; AIDS-226940; (1R)-1-(4-hydroxybenzyl)-6-methoxy-2-methyl-3,4-dihydro-1H-isoquinolin-7-ol; 7-Isoquinolinol, 1,2,3,4-tetrahydro-1-((4-hydroxyphenyl)methyl)-6-methoxy-2-methyl-, (R)-; (1R)-1-[(4-hydroxyphenyl)methyl]-6-methoxy-2-methyl-3,4-dihydro-1H-isoquinolin-7-ol; (R)-1,2,3,4-Tetrahydro-1-[(4-hydroxyphenyl)methyl]-6-methoxy-2-methyl-7-isoquinolinol; C05243; (-)-1(R)-N-Methylcoclaurine; AIDS226940; d-n-methyl coclaurine	C18H21NO3	299.36	CN1CCC2=CC(=C(C=C2C1CC3=CC=C(C=C3)O)O)OC
TCMBANKIN061550	Machiline	6-Methoxy-7-hydroxy-(1R)-[(4-hydroxyphenyl)methyl]-1,2,3,4-tetrahydroisoquinoline; (1R)-1-(4-hydroxybenzyl)-6-methoxy-1,2,3,4-tetrahydroisoquinolin-7-ol; D-Coclaurine; 7-Isoquinolinol, 1,2,3,4-tetrahydro-1-[(4-hydroxyphenyl)methyl]-6-methoxy-, (1R)-; AIDS226939; CHEBI:27482; (R)-1,2,3,4-Tetrahydro-1-[(4-hydroxyphenyl)methyl]-6-methoxy-7-isoquinolinol; (+)-1(R)-Coclaurine; (R)-Coclaurine; (+)-Coclaurine; (1R)-1-[(4-hydroxyphenyl)methyl]-6-methoxy-1,2,3,4-tetrahydroisoquinolin-7-ol; 7-Isoquinolinol, 1,2,3,4-tetrahydro-1-((4-hydroxyphenyl)methyl)-6-methoxy-, (R)-; AIDS-226939; 2196-60-3; C06349; d-coclaurine	C17H19NO3	285.34 g/mol	COC1=C(C=C2C(NCCC2=C1)CC3=CC=C(C=C3)O)O
TCMBANKIN061558	laurolitsine	(+)-Norboldine; CHEMBL487388; AC1L2JVN; 568-39-8; LS-97013; Dimethoxy-1,10 dihydroxy-2,9 nor-aporphine; Laurolistine; [(+)-norboldine]; MFCD06809897; UNII-5MT88IS14F; 6a-alpha-NORAPORPHINE-2,9-DIOL, 1,10-DIMETHOXY-; 890L186; (S)-1,10-Dimethoxy-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-2,9-diol; API0008028; Norboldine; Dimethoxy-1,10 dihydroxy-2,9 nor-aporphine [French]; 4H-Dibenzo[de,g]quinoline-2,9-diol, 5,6,6a,7-tetrahydro-1,10-dimethoxy-, (6aS)-; DTXSID30207641; C16984; 4H-Dibenzo(de,g)quinoline-2,9-diol, 5,6,6a,7-tetrahydro-1,10-dimethoxy-; Laurolitsine; 5890-18-6; 5MT88IS14F; D09GXL; BDBM50292446; (9S)-4,16-DIMETHOXY-10-AZATETRACYCLO[7.7.1.0(2),?.0(1)(3),(1)?]HEPTADECA-1(17),2(7),3,5,13,15-HEXAENE-5,15-DIOL; CHEBI:66557; ZINC2559362; 1,10-Dimethoxy-6a-alpha-noraporphine-2,9-diol; (6aS)-1,10-dimethoxy-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-2,9-diol; Norboldine; 1,10-Dimethoxy-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-2,9-diol; AIDS161652; 4H-dibenzo[de,g]quinoline-2,9-diol, 5,6,6a,7-tetrahydro-1,10-dimethoxy-; Dimethoxy-1,10 dihydroxy-2,9 nor-aporphine [French]; 4H-Dibenzo[de,g]quinoline-2,9-diol, 5,6,6a,7-tetrahydro-1,10-dimethoxy-, (6aS)-; AIDS-161652; 6a-alpha-NORAPORPHINE-2,9-DIOL, 1,10-DIMETHOXY-; 4H-Dibenzo(de,g)quinoline-2,9-diol, 5,6,6a,7-tetrahydro-1,10-dimethoxy-; Laurolitsine; 5890-18-6; 1,10-Dimethoxy-6a-alpha-noraporphine-2,9-diol; norboldine; InChI=1/C18H19NO4/c1-22-15-8-11-10(7-13(15)20)5-12-16-9(3-4-19-12)6-14(21)18(23-2)17(11)16/h6-8,12,19-21H,3-5H2,1-2H; 568-39-8	C18H19NO4	313.3 g/mol	COC1=C(C=C2CC3C4=C(C2=C1)C(=C(C=C4CCN3)O)OC)O

植物对应的疾病

疾病ID	病名	疾病类型	MeSH	参考文献

植物对应的靶点

靶点ID	基因名	基因别名	描述	染色体位置	Map_Location	基因类型